130 research outputs found
Strong coupling in massive gravity by direct calculation
We consider four-dimensional massive gravity with the Fierz-Pauli mass term.
The analysis of the scalar sector has revealed recently that this theory
becomes strongly coupled above the energy scale \Lambda = (M_{Pl}^2 m^4)^{1/5}
where m is the mass of the graviton. We confirm this scale by explicit
calculations of the four-graviton scattering amplitude and of the loop
correction to the interaction between conserved sources.Comment: 9 pages, 3 figures, some clarifications adde
Three-State Switching of an Anthracene Extended Bis-thiaxanthylidene with a Highly Stable Diradical State
A multistable molecular switching system based on an anthracene-extended bis-thiaxanthylidene with three individually addressable states that can be interconverted by electrochemical, thermal, and photochemical reactions is reported. Besides reversible switching between an open-shell diradical- and a closed-shell electronic configuration, our findings include a third dicationic state and control by multiple actuators. This dicationic state with an orthogonal conformation can be switched electrochemically with the neutral open-shell triplet state with orthogonal conformation, which was characterized by EPR. The remarkably stable diradical shows kinetic stability as a result of a significant activation barrier for isomerization to a more stable neutral closed-shell folded geometry. We ascribe this activation barrier of ΔG‡(293 K) = 25.7 kcal mol-1 to steric hindrance in the fjord region of the overcrowded alkene structure. The folded closed-shell state can be converted back to the diradical state by irradiation with 385 nm. The folded state can also be oxidized to the dicationic state. These types of molecules with multiple switchable states and in particular stable diradicals show great potential in the design of new functional materials such as memory devices, logic gates, and OFETs. </p
A comment on multiple vacua, particle production and the time dependent AdS/CFT correspondence
We give an explicit formulation of the time dependent AdS/CFT correspondence
when there are multiple vacua present in Lorentzian signature. By computing
sample two point functions we show how different amplitudes are related by
cosmological particle production. We illustrate our methods in two example
spacetimes: (a) a ``bubble of nothing'' in AdS space, and (b) an asymptotically
locally AdS spacetime with a bubble of nothing on the boundary. In both cases
the alpha vacua of de Sitter space make an interesting appearance.Comment: 9 page
Categorizing Different Approaches to the Cosmological Constant Problem
We have found that proposals addressing the old cosmological constant problem
come in various categories. The aim of this paper is to identify as many
different, credible mechanisms as possible and to provide them with a code for
future reference. We find that they all can be classified into five different
schemes of which we indicate the advantages and drawbacks.
Besides, we add a new approach based on a symmetry principle mapping real to
imaginary spacetime.Comment: updated version, accepted for publicatio
On the Holographic RG-flow and the Low-energy, Strong Coupling, Large N Limit
From the AdS/CFT correspondence, we learn that the classical evolution of
supergravity in the bulk can be reduced to a RG-flow equation for the dual
low-energy, strongly coupled and large N gauge theory on the boundary. This
result has been used to obtain interesting relations between the various terms
in the gravitational part of the boundary effective action, in particular the
term that affect the cosmological constant. It is found that once the
cosmological constant is cancelled in the UV theory, the RG-flow symmetry of
the boundary effective action automatically implies the existence of zero
cosmological constant solutions that extend all the way into the IR. Given the
standard (and well founded) contradiction between the RG-flow idea and the
observational evidence of a small cosmological constant, this is considered to
be an important progress, albeit incomplete, towards the final solution.
Motivated by this success, it would be interesting to see whether this
RG-stability extends outside the scope of strong 't Hooft coupling and large N
regime that are implicitly assumed in the de Boer-Verlinde-Verlinde
Hamilton-Jacobi formulation of the holographic RG-flow equations of the
boundary theory. In this paper, we address this question. Taking into account
the leading order corrections in the 1/N and parameters, we
derive new bulk/boundary relations, from which one can read all the local terms
in the boundary effective action. Next, we use the resulting constraints, to
examine whether the RG-stability of the cosmological constant extends to the
new coupling regime. It would be also interesting to use these constraints to
study the Randall-Sundrum scenario in this case.Comment: 27 pages, LateX, no figures, minor changes, typos corrected and added
more reference
Resposta reprodutiva de vacas de corte associada a marcadores moleculares relacionados Ă fertilidade
Explaining the impact of reconfigurable manufacturing systems on environmental performance: The role of top management and organizational culture
This study develops a theoretical model that links reconfigurable manufacturing systems with top management beliefs, participation, and environmental performance, drawing on agency theory and organizational culture. The study takes into account the possible confounding effects of organization size and organizational compatibility. Drawing on responses from 167 top managers, the results of hypothesis testing suggest that (i) higher top management participation, being influenced by top management beliefs, leads to higher chances of RMS becoming adopted by organizations as their manufacturing strategy; (ii) organizational culture moderates the relationship between the level of top management participation and RMS (and manufacturing strategies) adoption; and (iii) higher re-configurability of manufacturing systems leads to better environmental performance. Furthermore, we integrate Agency Theory and organizational culture to explain the role of top management beliefs and participation in achieving environmental performance via RMS. Finally, we offer guidance to those managers who would like to engage in leveraging top management commitment for achieving environmental performance, and outline further research directions
Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma
Genome-wide association studies (GWAS) have transformed our understanding of susceptibility to multiple myeloma (MM), but much of the heritability remains unexplained. We report a new GWAS, a meta-analysis with previous GWAS and a replication series, totalling 9974 MM cases and 247,556 controls of European ancestry. Collectively, these data provide evidence for six new MM risk loci, bringing the total number to 23. Integration of information from gene expression, epigenetic profiling and in situ Hi-C data for the 23 risk loci implicate disruption of developmental transcriptional regulators as a basis of MM susceptibility, compatible with altered B-cell differentiation as a key mechanism. Dysregulation of autophagy/apoptosis and cell cycle signalling feature as recurrently perturbed pathways. Our findings provide further insight
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