Influencia del porrismo en los hábitos de estudio de los adolescentes pertenecientes al grupo cheers xtreme de Armenia Quindío

Maestría en Educación y Desarrollo Humano, Facultad de Ciencias Sociales y Humanas.La presente investigación se realiza con el fin de demostrar que efectos tiene el deporte sobre los hábitos de estudio, la pertinencia de la siguiente es que se cuenta con los deportistas del club para poder llevar a cabo la investigación, así poder dar la importancia que tiene esta práctica y tratar de combatir un problema muy común en la adolescencia que es el bajo rendimiento académico, la falta de motivación por aprender, evitar la medicación en los jóvenes viendo el deporte como alternativa. Hay distintas investigaciones que hacen referencia al deporte como una forma de mediar distintas problemáticas sociales, físicas, mentales y espirituales, lo novedoso de este estudio, es que se investigara con una disciplina deportiva diferente a lo convencional como el porrismo, el cual viene tomando fuerza no solo en el país también en diferentes partes del mundo y se está relacionado con los hábitos de estudi

Métodos de entrenamiento utilizados por los entrenadores de los clubes de natación de la provincia de Imbabura y su relación con la preparación de las pruebas de resistencia en deportistas de 14-18 años en el año 2014.

Determinar los tipos de métodos de entrenamiento utilizados por los entrenadores de los clubes de natación de la provincia de Imbabura y su relación con la preparación de las pruebas de resistencia en deportistas de 14 - 16 años en el año 2014.La presente investigación trata de los métodos que los entrenadores de natación utilizan y su relación con la resistencia en deportistas de 14 a 16 años en la provincia de Imbabura. El propósito del presente trabajo de investigación fue el de precisar cuál es el nivel de conocimientos de los entrenadores de natación acerca de los métodos de entrenamiento con relación a la resistencia, además diagnosticar el grado de preparación en lo que a resistencia se refiere de los deportistas de la provincia. Para la confección del marco teórico se buscó bibliografía actualizada y especializada en libros e internet que contengan información de la resistencia y también a los métodos de entrenamiento. Por la característica de la investigación esta se enmarca en un proyecto factible que se basó en una investigación inductiva, deductiva, analítico y estadístico. Los investigados fueron los entrenadores y los deportistas de la provincia pertenecientes a las diferentes instituciones que practican natación en la provincia de Imbabura. Las técnicas de investigación utilizadas fueron la encuesta y los test que permitieron recabar la información que se encuentra relacionada con el problema de estudio. Una vez obtenida la información se tabuló para conocer los resultados para luego elaborar una guía metodológica del uso correcto de los métodos de entrenamiento para el desarrollo de la resistencia en los deportistas de Imbabura. La guía metodológica contendrá la metodología de secuencia lógica de uso de los métodos con sus características a lo largo de un espacio de tiempo. La resistencia representa un papel importante en la disciplina de la natación y su adecuado desarrollo constituirá una base para la preparación técnica, táctica, física y psicológica del deportista.Licenciatur

Self‐assembling Venturi‐like peptide nanotubes

We describe the design and synthesis of self-assembling peptide nanotubes that have an internal filter area and whose length and internal diameters, at the entrance and in the constricted area, are precisely controlledThis work was supported by the Spanish Ministry of Economy and Competitivity (Mineco) and the ERDF (CTQ2013‐43264‐R), and by the Xunta de Galicia and the ERDF (EM2014/011). A. F. and H. L. O. thank Mineco for their FPU contracts. We also thank the ORFEO‐CINCA network and Mineco (CTQ2014‐ 51912‐REDC). We very much appreciate Dr. Ignacio Alfonso (IQAC‐CSIC) for his help in designing DOSY experimentsNO

Supramolecular functional assemblies: dynamic membrane transporters and peptide nanotubular composites

NOTICE: This is the peer reviewed version of the following article: Fuertes A, Juanes M, Granja J, Montenegro J. Supramolecular functional assemblies: dynamic membrane transporters and peptide nanotubular composites. Chem Commun. 2017;53(56):7861-7871. [doi: 10.1039/C7CC02997G]. This article may be used for non-commercial purposes in accordance with RSC Terms and Conditions for self-archivingThe fabrication of functional molecular devices constitutes one of the most important current challenges for chemical sciences. The complex processes accomplished by living systems continuously demand the assistance of non-covalent interactions between molecular building blocks. Additionally, these building blocks (proteins, membranes, nucleotides) are also constituted by self-assembled structures. Therefore, supramolecular chemistry is the discipline required to understand the properties of the minimal self-assembled building blocks of living systems and to develop new functional smart materials. In the first part of this feature article, we highlight selected examples of the preparation of supramolecular membrane transporters with special emphasis in the application of dynamic covalent bonds. In the second section of the paper we review recent breakthroughs in the preparation of peptide nanotubes hybrids with functional applications. The development of these devices constitutes an exciting process from where we can learn how to understand and manipulate supramolecular functional assembliesWe acknowledge funding from the Spanish Agencia Estatal de Investigación (AEI) (CTQ2014-59646-R and CTQ2016-78423-R), the Xunta de Galicia (ED431G/09 and 2016-AD031) and the ERDF. A. F. and M. J. received F. P. U. and F. P. I. fellowships from MECD and MINECO. J. M. received a Ramon y Cajal Grant (RYC-2013-13784), an ERC Starting Investigator Grant (DYNAP-677786) and a Young Investigator Grant from the Human Frontier Research Program (RGY0066/2017)S

Linking short- to medium-term beach dune dynamics to local features under wave and wind actions: a northern portuguese case study

Many coasts suffer from prevailing erosion, with them being particularly vulnerable to predicted climate change impacts, threatening coastal ecosystems, their services, infrastructures and populations. Understanding coastal morpho-sedimentary dynamics is thus essential for coastal management. However, coastal vulnerability may differ locally, depending on exposure/protection and local geological and morpho-hydrodynamical features, suggesting that a local approach to erosion risk assessment is needed to identify and understand local patterns. Digital elevation models of a 14 km long coastal stretch in northern Portugal that were extracted from aerial surveys obtained between November 2008 and February 2019 were analysed to quantify changes in shoreline position and sediment budgets, both for the whole study area and for distinct beach segments. The observed dynamics were subsequently analysed by considering prevailing wave and wind intensities and directions. Overall and during the decade analysed, the beach–dune system of the studied stretch slightly increased in volume (0.6%), although the shoreline retreated (by 1.6 m on average). Temporal variability in coastal dynamics was observed at all of the temporal scales considered—from seasons to 5-year periods—with them being related to variability in ocean and wind patterns. There was a trend from accretional to erosional conditions, with the first 5-year period showing a mean increase in the beach–dune system’s volume of 0.6% and a mean shoreline progradation of 1.5 m, followed by 5-years with 0.0% volume change and 3.1 m shoreline retreat. Locally, the dynamics were very variable, with shoreline dynamics ranging from 24.0 m regression to 51.5 m progradation, and sediment budgets from 213.8 m3 loss to 417.0 m3 gain, per segment and for the decade. Stretches with relatively stable morphologies and others with erosional or accretional trends were found, depending on the beach type, shoreline orientation and the presence of defence structures. Rocky beaches were the least dynamic and sandy beaches the most dynamic, with mean shoreline position changes of 0.0 m and −3.4 m, respectively, and mean sediment budgets of −1.1 m3 and −2.9 m3 per linear meter of coastline, respectively, for the studied decade. The observed dynamics showed how local conditions interacted with meteo-ocean conditions in shaping local morpho-sedimentary dynamics, stressing the importance of a local approach to coastal erosion monitoring and risk assessment.European Union MarRISK project: Adaptación costera ante el Cambio Climático: conocer los riesgos y aumentar la resiliencia (0262_MarRISK_1_E) through EP INTERREG V A España-Portugal (POCTEP) program and the project INNOVMAR-Innovation and Sustainability in the Management and Exploitation of Marine Resources (NORTE-01-0145-FEDER-000035, within Research Line ECOSERVICES), supported by NORTE 2020, under the PORTUGAL 2020 Partnership Agreement, through the ERD

The Effect of Anisotropic Focusing of Lamb Modes on a Carbon-Epoxy Plain Woven Fabric Composite Plate

10 páginas, 8 figuras, 1 tabla. 6th International Symposium on NDT in Aerospace, 12-14th November 2014, Madrid, SpainThe medium anisotropy give rise to interesting effects in the physics of wave propagation: the angular dependence of the group velocity, the skew angle between pha se and group velocities, and the elastic focusing leading to the concentration of wave energy in dete rminated directions. All these effects are mode dependent and must be taken into account to choose the ad equate propagating mode in NDE or SHM applications. In this article the dispersion curves of p hase and group velocities, and the patterns of wave focusing for the A0 and S0 modes are theoretically obt ained and verified experimentally. The angular dependence of the group velocity and the effect of the anisotropic elastic focusing is studied in a 1.97 mm-thickness multilayer carbon-epoxy plain woven fab ric composite. The time traces are obtained by scanning the plate with the aid of a retro-reflective film st uck to the surface using a laser Doppler vibrometer. A good agreement between the theory and the expe rimental results was obtained. The Maris factor corresponding to the A0 mode shows smoother angular v ariation than that of the S0 mode which depends much more on the direction.The authors wish to thank to the CAPES Foundation, Ministry of Education of Brazil and to the Ministerio de Economía y Competitividad del Gobierno de Esp aña (project FIS2013-46829-R) for partially support the work, and to the Alltec Materiais Compostos for preparing the laminate samples.Peer reviewe

Small harbours risks: lowering for fishery and increasing erosion. The case of Portinho da Aguda (NW Portugal)

The harbour Portinho da Aguda was established between October 2001 and July 2002, at Aguda village. The area presented some rocky outcrops that, in some way, protected the coastal border against direct wave impact, on a coastal stretch where erosion has been a continuing problem. In an attempt to create a protected area for the entrance and way out of the community’s small fishing boats a detached curved breakwater was built. After some months, still during the works, a wedge beach was created against the temporary groin, promoting the enlargement of the beach located updrift and the erosion of the downdrift coastal segment (Granja Beach). To remediate this situation, sand transfer from the updrift area was done, to compensate the accentuated loss of sediments of Granja Beach, a famous old seaside resort. But, due to the very high energetic conditions, sands did not remain on the beach, and new spring to early summer recharges became necessary. Based on results from a comprehensive monitoring program of the coastal border north and south of Aguda between 2001 and 2009 with DGPS, sedimentary budgets were calculated and morphological changes identified, comparing situations before and after breakwater construction. Breakwater impacts on neighbouring areas of the harbour are presented, as are the evolution trends of the harbour itself. Some possible mitigation measures are pointed out and the efficiency and relevance of this kind of coastal structures is discussed

Bibliografía de Manuel Tuñón de Lara

Libros Espagne, París, Éditions du Seuil, 1956, 192 p. (en francés, escrito en colaboración con Dominique Aubier y traducido al español, inglés, italiano y holandés). From Incas to Indios, París, Éditions Delpire, 1956. Antonio Machado, París, Pierre Seghers, 1960, 221 p. (en francés). La España del siglo XIX (1808-1914), París, Librería Española, 1961, 356 p. (varias ediciones). Reediciones: Barcelona, Laia, 1973 (varias ediciones en dos tomos), y Madrid, Akal, 2000, dos tomos. Presentación ..

Effects of histamine H1 receptor signaling on glucocorticoid receptor activity. Role of canonical and non-canonical pathways

Histamine H1 receptor (H1R) antagonists and glucocorticoid receptor (GR) agonists are used to treat inflammatory conditions such as allergic rhinitis, atopic dermatitis and asthma. Consistent with the high morbidity levels of such inflammatory conditions, these receptors are the targets of a vast number of approved drugs, and in many situations their ligands are co-administered. However, this drug association has no clear rationale and has arisen from clinical practice. We hypothesized that H1R signaling could affect GR-mediated activity, impacting on its transcriptional outcome. Indeed, our results show a dual regulation of GR activity by the H1R: a potentiation mediated by G-protein βγ subunits and a parallel inhibitory effect mediated by Gαq-PLC pathway. Activation of the H1R by its full agonists resulted in a composite potentiating effect. Intriguingly, inactivation of the Gαq-PLC pathway by H1R inverse agonists resulted also in a potentiation of GR activity. Moreover, histamine and clinically relevant antihistamines synergized with the GR agonist dexamethasone to induce gene transactivation and transrepression in a gene-specific manner. Our work provides a delineation of molecular mechanisms underlying the widespread clinical association of antihistamines and GR agonists, which may contribute to future dosage optimization and reduction of well-described side effects associated with glucocorticoid administration.Fil: Zappia, Carlos Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Farmacológicas (i); Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Farmacología. Cátedra de Química Medicinal; ArgentinaFil: Granja Galeano, Gina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Farmacológicas (i); Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Farmacología. Cátedra de Química Medicinal; ArgentinaFil: Fernandez, Natalia Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Farmacológicas (i); Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Farmacología. Cátedra de Química Medicinal; ArgentinaFil: Shayo, Carina Claudia. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); ArgentinaFil: Davio, Carlos Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Farmacológicas (i); Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Farmacología. Cátedra de Química Medicinal; ArgentinaFil: Fitzsimons, Carlos P.. University Of Amsterdam; Países BajosFil: Monczor, Federico. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Farmacológicas (i); Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Farmacología. Cátedra de Química Medicinal; Argentin

Effectiveness of Dry Needling versus Placebo on Gait Performance, Spasticity, Electromyographic Activity, Pain, Range-of-Movement and Quality of Life in Patients with Multiple Sclerosis: A Randomized Controlled Trial Protocol

Dry needling (DN) is an emerging technique commonly used in neurological and musculoskeletal pain conditions, but there have been no previous studies in patients with multiple sclerosis (pwMS). This trial aims to assess the efficacy of deep DN, compared with sham placebo DN, on gait performance, spasticity level, pain, electromyographic activity, range-of-movement (ROM) and quality of life in pwMS. Forty adults with MS were randomly assigned to one study group. The DN group will undergo 2 sessions (once per week) using DN over the rectus femoris (RF) and gastrocnemius medialis (GM) muscles at the lower extremity with higher spasticity. The placebo group will receive the same protocol using a sham placebo needle (Dong Bang needle). Outcome measures will include gait performance, using the GaitRite(R) system, spasticity level with the Modified Ashworth Scale, superficial electromyographic activity of RF and GM, pain (pressure algometer), ROM (goniometer), and quality of life (Musiqol). This study is the first investigating the short-term effect of DN, compared with placebo, in pwMS, and taking into account the possible changes in the electromyographic activity of the lower limb. Therefore, the results may help to understand the suitability of using this technique in the clinical setting for this population. Trial registration: ACTRN12619000880145