Characteristics of Venezuelan school refusers toward the development of a high-risk profile

Journal ArticleParent, teacher, and child reports were used to identify situational and personal factors associated with school refusal in 114 3- to 13-year-old Venezuelan children. The sample consisted of 57 school refusers and 57 nonrefusers matched on age, school, and sex. As compared with nonrefusers, the refusers had changed schools more often, were rated as more dependent, had more school-related fears, and were perceived by their parents as more difficult to manage

Molecular and metabolic mechanisms associated with fleshy fruit quality

Funding to AF was provided by the Portuguese Foundation for Science and Technology (FCT Investigator IF/00169/2015, PEst-OE/BIA/UI4046/2014). Research in the AG lab was supported by the EC H2020 Program:TRADITOM-634561 and TOMGEM679796 and networking activities by COST FA1106.Fortes, AM.; Granell Richart, A.; Pezzotti, M.; Bouzayen, M. (2017). Molecular and metabolic mechanisms associated with fleshy fruit quality. Frontiers in Plant Science. 8:6-10. https://doi.org/10.3389/fpls.2017.01236S6108Agudelo-Romero, P., Erban, A., Sousa, L., Pais, M. S., Kopka, J., & Fortes, A. M. (2013). Search for Transcriptional and Metabolic Markers of Grape Pre-Ripening and Ripening and Insights into Specific Aroma Development in Three Portuguese Cultivars. PLoS ONE, 8(4), e60422. doi:10.1371/journal.pone.0060422Fortes, A. M., & Gallusci, P. (2017). Plant Stress Responses and Phenotypic Plasticity in the Epigenomics Era: Perspectives on the Grapevine Scenario, a Model for Perennial Crop Plants. Frontiers in Plant Science, 08. doi:10.3389/fpls.2017.00082Fortes, A., Teixeira, R., & Agudelo-Romero, P. (2015). Complex Interplay of Hormonal Signals during Grape Berry Ripening. Molecules, 20(5), 9326-9343. doi:10.3390/molecules20059326Liu, R., How-Kit, A., Stammitti, L., Teyssier, E., Rolin, D., Mortain-Bertrand, A., … Gallusci, P. (2015). A DEMETER-like DNA demethylase governs tomato fruit ripening. Proceedings of the National Academy of Sciences, 112(34), 10804-10809. doi:10.1073/pnas.150336211

Tucumanin, a β-hydroxy-γ-lactone bistetrahydrofuranic acetogenin from Annona cherimolia, is a potent inhibitor of mitochondrial complex I

A new β-hydroxy-γ-methyl-γ-lactone bistetrahydrofuranic acetogenin, tucumanin, with the infrequent symmetrical threo/trans/threo/trans/ threo relative configuration at the tetrahydrofuran rings was isolated from Annona cherimolia (Annonaceae) seeds. The inhibitory potency on the mitochondrial complex I of acetogenins with this relative configuration (tucumanin and asimicin) was compared with that shown by the corresponding pairs with an asymmetrical threo/trans/threo/trans/erythro relative configuration (laherradurin/rolliniastatin-2, and itrabin/molvizarin). All these compounds act as selective inhibitors of mitochondrial complex 1 in the 0.18 - 1.55 nM range.Fil: Barrachina, Isabel. Universidad de Valencia; EspañaFil: Neske, Adriana. Universidad Nacional de Tucumán; ArgentinaFil: Granell, Susana. Universidad de Valencia; EspañaFil: Bermejo, Almudena. Universidad de Valencia; EspañaFil: Chahboune, Nadia. Universidad de Valencia; EspañaFil: El Aouad, Noureddine. Universidad de Valencia; EspañaFil: Alvarez, Olga. Universidad Nacional de Tucumán; ArgentinaFil: Bardon, Alicia del Valle. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Química del Noroeste. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia. Instituto de Química del Noroeste; Argentina. Universidad Nacional de Tucumán; ArgentinaFil: Zafra Polo, M. Carmen. Universidad de Valencia; Españ

Innovations to Improve Lung Isolation Training for Thoracic Anesthesia: A Narrative Review.

A double-lumen tube or bronchial blocker positioning using flexible bronchoscopy for lung isolation and one-lung ventilation requires specific technical competencies. Training to acquire and retain such skills remains a challenge in thoracic anesthesia. Recent technological and innovative developments in the field of simulation have opened up exciting new horizons and possibilities. In this narrative review, we examine the latest development of existing training modalities while investigating, in particular, the use of emergent techniques such as virtual reality bronchoscopy simulation, virtual airway endoscopy, or the preoperative 3D printing of airways. The goal of this article is, therefore, to summarize the role of existing and future applications of training models/simulators and virtual reality simulators for training flexible bronchoscopy and lung isolation for thoracic anesthesia