Reduced model for the thermo-fluid dynamic analysis of a power transformer radiator working in ONAF mode

This work introduces an extension of the semi-analytical reduced model presented in G. Ríos Rodriguez et.al., App Thermal Eng, 112:1271–1280 (2016); with the aim of analyzing the thermo-fluid dynamic behavior of a power transformer radiator working in ONAF (Oil Natural Air Forced) mode, considering vertical blowing of the fans. The objective of this research paper is the development of a numerical tool to be used during the design process of power transformers in order to obtain more detailed information about the radiators performance, either they are working in ONAF or ONAN (Oil Natural Air Natural) mode. Since it is observed both in the experimental measurements and in the numerical simulations that not all the radiator panels are blown by a single fan, the reduced model here presented considers a mixed situation wherein the heat is removed by natural convection in a fraction of the radiator while in the rest the heat is removed by forced convection. As a consequence, besides adding to the set of conservation equations introduced in G. Ríos Rodriguez et.al., App Thermal Eng, 112:1271– 1280 (2016); those corresponding to the momentum and energy balance for considering forced heat convection transfer, there appears the need of introducing additional equations for coupling the natural and forced heat convection transfer models. The reduced model developed in this work is applied to estimate different characteristic parameters of a power transformer radiator working in ONAF mode, like the oil flow rate, dissipated power, outlet and inlet oil temperatures, among others. The computed results are compared to those obtained by CFD simulations and experimental measurements carried out on an ad-hoc workbench for validation purposes. It is found that the reduced model reproduces with acceptable accuracy the values of the most important design variables at a very low computation cost. In this manner, it can be considered as a reliable and valuable tool in the design of power transformers, allowing to carry out parametric studies.Publicado en: Mecánica Computacional vol. XXXV, no. 4Facultad de Ingenierí

Reduced model for the thermo-fluid dynamic analysis of a power transformer radiator working in ONAF mode

This work introduces an extension of the semi-analytical reduced model presented in G. Ríos Rodriguez et.al., App Thermal Eng, 112:1271–1280 (2016); with the aim of analyzing the thermo-fluid dynamic behavior of a power transformer radiator working in ONAF (Oil Natural Air Forced) mode, considering vertical blowing of the fans. The objective of this research paper is the development of a numerical tool to be used during the design process of power transformers in order to obtain more detailed information about the radiators performance, either they are working in ONAF or ONAN (Oil Natural Air Natural) mode. Since it is observed both in the experimental measurements and in the numerical simulations that not all the radiator panels are blown by a single fan, the reduced model here presented considers a mixed situation wherein the heat is removed by natural convection in a fraction of the radiator while in the rest the heat is removed by forced convection. As a consequence, besides adding to the set of conservation equations introduced in G. Ríos Rodriguez et.al., App Thermal Eng, 112:1271– 1280 (2016); those corresponding to the momentum and energy balance for considering forced heat convection transfer, there appears the need of introducing additional equations for coupling the natural and forced heat convection transfer models. The reduced model developed in this work is applied to estimate different characteristic parameters of a power transformer radiator working in ONAF mode, like the oil flow rate, dissipated power, outlet and inlet oil temperatures, among others. The computed results are compared to those obtained by CFD simulations and experimental measurements carried out on an ad-hoc workbench for validation purposes. It is found that the reduced model reproduces with acceptable accuracy the values of the most important design variables at a very low computation cost. In this manner, it can be considered as a reliable and valuable tool in the design of power transformers, allowing to carry out parametric studies.Publicado en: Mecánica Computacional vol. XXXV, no. 4Facultad de Ingenierí

Magnetotransport of dirty-limit van Hove singularity quasiparticles

Tuning of electronic density-of-states singularities is a common route to unconventional metal physics. Conceptually, van Hove singularities are realized only in clean two-dimensional systems. Little attention has therefore been given to the disordered (dirty) limit. Here, we provide a magnetotransport study of the dirty metamagnetic system calcium-doped strontium ruthenate. Fermi liquid properties persist across the metamagnetic transition, but with an unusually strong variation of the Kadowaki-Woods ratio. This is revealed by a strong decoupling of inelastic electron scattering and electronic mass inferred from density-of-state probes. We discuss this Fermi liquid behavior in terms of a magnetic field tunable van Hove singularity in the presence of disorder. More generally, we show how dimensionality and disorder control the fate of transport properties across metamagnetic transitions

Risk factors of anterior cruciate ligament tears: Neuromuscular status

Peer reviewe

Thermal analysis of 8.5 MVA disk-type power transformer cooled by biodegradable ester oil working in ONAN mode by using advanced EMAG–CFD–CFD coupling

Power transformers are the first devices used to transfer the electrical energy produced in power plants to the grid to supply the industrial and individual receivers with electricity. The heat generation in windings and core, being an effect of the power losses, is usually dissipated in large units by using mineral oils, which are harmful to the environment. Nowadays, the industry and global society seek environmentally-friendly alternatives. One of the most promising substitute for their high biodegradability, safety in operation, and favourable thermo-physical properties are natural ester oils. For this reason, a numerical study of 8.5 MVA disk-type power transformer cooled using conventional mineral oil and a commercially used rapeseed ester oil is presented in this paper. Moreover, due to different thermal behaviour of the considered oils, the comparison was made for the unit working in different seasons of hot and moderate climate zones (Argentina and Poland). In the numerical approach, electromagnetic (EMAG) and computational fluid dynamics (CFD) models were used for a detailed study of the selected device. In particular, a novel and very efficient EMAG–CFD–CFD coupling procedure was developed to assess the cooling of the large power transformer. Such a coupled computational procedure allowed for the detailed investigation of the power loss, oil flow characteristics, and temperatures with a satisfying computational effort. The results showed that the average windings temperatures are higher by 2–9 K when the ester oil is used, dependent on the ambient conditions. The hotspot temperature in the low voltage windings increased by up to 9 K and up to 18 K in the high voltage windings using ester oil. According to the results, the oil duct construction requires modification in the high voltage region for transformers cooled using mineral oil in cold climate conditions.Fil: Stebel, Michal. Silesian University Of Technology; PoloniaFil: Kubiczek, Krzysztof. Silesian University Of Technology; PoloniaFil: Rios Rodriguez, Gustavo Adolfo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Centro de Investigaciones en Métodos Computacionales. Universidad Nacional del Litoral. Centro de Investigaciones en Métodos Computacionales; ArgentinaFil: Palacz, Michal. Silesian University Of Technology; PoloniaFil: Garelli, Luciano. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Centro de Investigaciones en Métodos Computacionales. Universidad Nacional del Litoral. Centro de Investigaciones en Métodos Computacionales; ArgentinaFil: Melka, Bartlomiej. Silesian University Of Technology; PoloniaFil: Haida, Michal. Silesian University Of Technology; PoloniaFil: Bodys, Jakub. Silesian University Of Technology; PoloniaFil: Nowak, Andrzej J.. Silesian University Of Technology; PoloniaFil: Lasek, Pawel. Silesian University Of Technology; PoloniaFil: Stepien, Mariusz. Silesian University Of Technology; PoloniaFil: Pessolani, Francisco. Tadeo Czerweny S.a.; ArgentinaFil: Amadei, Mauro. Tadeo Czerweny S.a.; ArgentinaFil: Granata, Daniel. Tadeo Czerweny S.a.; ArgentinaFil: Storti, Mario Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Centro de Investigaciones en Métodos Computacionales. Universidad Nacional del Litoral. Centro de Investigaciones en Métodos Computacionales; ArgentinaFil: Smolka, Jacek. Silesian University Of Technology; Poloni

Spin-orbit coupling induced Van Hove singularity in proximity to a Lifshitz transition in Sr4Ru3O10

Funding: CAM, MN and PW gratefully acknowledge funding from the Engineering and Physical Sciences Research Council through EP/R031924/1 and EP/S005005/1, IB through the International Max Planck Research School for Chemistry and Physics of Quantum Materials and LCR from a fellowship from the Royal Commission of the Exhibition of 1851. RA, RF and AV thank the EU’s Horizon 2020 research and innovation program under Grant Agreement No. 964398 (SUPERGATE).Van Hove singularities (VHss) in the vicinity of the Fermi energy often play a dramatic role in the physics of strongly correlated electron materials. The divergence of the density of states generated by VHss can trigger the emergence of new phases such as superconductivity, ferromagnetism, metamagnetism, and density wave orders. A detailed understanding of the electronic structure of these VHss is therefore essential for an accurate description of such instabilities. Here, we study the low-energy electronic structure of the trilayer strontium ruthenate Sr4Ru3O10, identifying a rich hierarchy of VHss using angle-resolved photoemission spectroscopy and millikelvin scanning tunneling microscopy. Comparison of k-resolved electron spectroscopy and quasiparticle interference allows us to determine the structure of the VHss and demonstrate the crucial role of spin-orbit coupling in shaping them. We use this to develop a minimal model from which we identify a new mechanism for driving a field-induced Lifshitz transition in ferromagnetic metals.Peer reviewe

The Effect of Osmolytes on Protein Fibrillation

Osmolytes are small molecules that are exploited by cells as a protective system against stress conditions. They favour compact protein states which makes them stabilize globular proteins in vitro and promote folding. Conversely, this preference for compact states promotes aggregation of unstructured proteins. Here we combine a brief review of the effect of osmolytes on protein fibrillation with a report of the effect of osmolytes on the unstructured peptide hormone glucagon. Our results show that osmolytes either accelerate the fibrillation kinetics or leave them unaffected, with the exception of the osmolyte taurine. Furthermore, the osmolytes that affected the shape of the fibrillation time profile led to fibrils with different structure as revealed by CD. The structural changes induced by Pro, Ser and choline-O-sulfate could be due to specific osmolytes binding to the peptides, stabilizing an otherwise labile fibrillation intermediate

Ghrelin Attenuates the Osteoblastic Differentiation of Vascular Smooth Muscle Cells through the ERK Pathway

Vascular calcification results from osteoblastic differentiation of vascular smooth muscle cells (VSMCs) and is a major risk factor for cardiovascular events. Ghrelin is a newly discovered bioactive peptide that acts as a natural endogenous ligand of the growth hormone secretagog receptor (GHSR). Several studies have identified the protective effects of ghrelin on the cardiovascular system, however research on the effects and mechanisms of ghrelin on vascular calcification is still quite rare. In this study, we determined the effect of ghrelin on osteoblastic differentiation of VSMCs and investigated the mechanism involved using the two universally accepted calcifying models of calcifying vascular smooth muscle cells (CVSMCs) and beta-glycerophosphate (beta-GP)-induced VSMCs. Our data demonstrated that ghrelin inhibits osteoblastic differentiation and mineralization of VSMCs due to decreased alkaline phosphatase (ALP) activity, Runx2 expression, bone morphogenetic protein-2 (BMP-2) expression and calcium content. Further study demonstrated that ghrelin exerted this suppression effect via an extracellular signal-related kinase (ERK)-dependent pathway and that the suppression effect of ghrelin was time dependent and dose dependent. Furthermore, inhibition of the growth hormone secretagog receptor (GHSR), the ghrelin receptor, by siRNA significantly reversed the activation of ERK by ghrelin. In conclusion, our study suggests that ghrelin may inhibit osteoblastic differentiation of VSMCs through the GHSR/ERK pathway

The genetic architecture of membranous nephropathy and its potential to improve non-invasive diagnosis

Membranous Nephropathy (MN) is a rare autoimmune cause of kidney failure. Here we report a genome-wide association study (GWAS) for primary MN in 3,782 cases and 9,038 controls of East Asian and European ancestries. We discover two previously unreported loci, NFKB1 (rs230540, OR = 1.25, P = 3.4 × 10-12) and IRF4 (rs9405192, OR = 1.29, P = 1.4 × 10-14), fine-map the PLA2R1 locus (rs17831251, OR = 2.25, P = 4.7 × 10-103) and report ancestry-specific effects of three classical HLA alleles: DRB1*1501 in East Asians (OR = 3.81, P = 2.0 × 10-49), DQA1*0501 in Europeans (OR = 2.88, P = 5.7 × 10-93), and DRB1*0301 in both ethnicities (OR = 3.50, P = 9.2 × 10-23 and OR = 3.39, P = 5.2 × 10-82, respectively). GWAS loci explain 32% of disease risk in East Asians and 25% in Europeans, and correctly re-classify 20-37% of the cases in validation cohorts that are antibody-negative by the serum anti-PLA2R ELISA diagnostic test. Our findings highlight an unusual genetic architecture of MN, with four loci and their interactions accounting for nearly one-third of the disease risk