4,984 research outputs found
An Ontario Libraries' Network, or Cooperative Entanglement
While I
accepted the invitation to discuss the College Bibliocentre at
this Clinic, I cannot
say that I did so with equanimity. Quite apart from many
organizational difficulties, the systems both in operation and in varying stages
of
development at the College Bibliocentre, have evolved from practical emersion
without the benefit of the finite
planning or initial test and research proce-
dures from
grant aids that many others have experienced. This is why I
adopted the latter part of my title for this paper.
I was asked
particularly to discuss the techniques we are using to
acquire the necessary input to the various systems. However, if I was asked to
underline what I considered to be the
major problems facing the development
of a central technical service unit, the technicalities of how to
input would be
the least concern. The
major problems are those beyond the technological
requirements how to achieve the degree of coordination required and, in
particular, how to overcome the financial hazards which face such an organiza-
tion.published or submitted for publicatio
Analysis of the Brinkman-Forchheimer equations with slip boundary conditions
In this work, we study the Brinkman-Forchheimer equations driven under slip
boundary conditions of friction type. We prove the existence and uniqueness of
weak solutions by means of regularization combined with the Faedo-Galerkin
approach. Next we discuss the continuity of the solution with respect to
Brinkman's and Forchheimer's coefficients. Finally, we show that the weak
solution of the corresponding stationary problem is stable
By-Pass Diode Temperature Tests of a Solar Array Coupon Under Space Thermal Environment Conditions
Tests were performed on a 56-cell Advanced Triple Junction solar array coupon whose purpose was to determine margin available for bypass diodes integrated with new, large multi-junction solar cells that are manufactured from a 4-inch wafer. The tests were performed under high vacuum with cold and ambient coupon back-side. The bypass diodes were subjected to a sequence of increasing discrete current steps from 0 Amp to 2.0 Amp in steps of 0.25 Amp. At each current step, a temperature measurement was obtained via remote viewing by an infrared camera. This paper discusses the experimental methodology, including the calibration of the thermal imaging system, and the results
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Summary of Prior Work on Joining of Oxide Dispersion-Strengthened Alloys
There is a range of joining techniques available for use with ODS alloys, but care should be exercised in matching the technique to the final duty requirements of the joint. The goal for joining ODS alloys is a joint with no local disruption of the distribution of the oxide dispersion, and no significant change in the size and orientation of the alloy microstructure. Not surprisingly, the fusion welding processes typically employed with wrought alloys produce the least satisfactory results with ODS alloys, but some versions, such as fusion spot welding, and the laser and electron-beam welding technologies, have demonstrated potential for producing sound joints. Welds made using solid-state spot welding reportedly have exhibited parent metal properties. Thus, it is possible to employ processes that result in significant disruption of the alloy microstructure, as long as the processing parameters are adjustment to minimize the extent of or influence of the changes in the alloy microstructure. Selection among these joining approaches largely depends on the particular application and component configuration, and an understanding of the relationships among processing, alloy microstructure, and final properties is key. Recent developments have resulted in friction welding evolving to be a prime method for joining ODS sheet products, and variants of brazing/diffusion bonding have shown excellent promise for use with tubes and pipes. The techniques that come closest to the goal defined above involve solid-state diffusion bonding and, in particular, it has been found that secondary recrystallization of joints made by pulsed plasma-assisted diffusion can produce the desired, continuous, large alloy grain structure through the joint. Such joints have exhibited creep rupture failure at >82% of the load needed to fail the monolithic parent alloy at 1000 C
On Perturbations in Warm Inflation
Warm inflation is an interesting possibility of describing the early
universe, whose basic feature is the absence, at least in principle, of a
preheating or reheating phase. Here we analyze the dynamics of warm inflation
generalizing the usual slow-roll parameters that are useful for characterizing
the inflationary phase. We study the evolution of entropy and adiabatic
perturbations, where the main result is that for a very small amount of
dissipation the entropy perturbations can be neglected and the purely adiabatic
perturbations will be responsible for the primordial spectrum of
inhomogeneities. Taking into account the COBE-DMR data of the cosmic microwave
background anisotropy as well as the fact that the interval of inflation for
which the scales of astrophysical interest cross outside the Hubble radius is
about 50 e-folds before the end of inflation, we could estimate the magnitude
of the dissipation term. It was also possible to show that at the end of
inflation the universe is hot enough to provide a smooth transition to the
radiation era.Comment: 12 pages, no figures, requires revtex4. Further explanation on the
origin of the entropy perturbation, reference added and minor notation
change. Version accepted for publication in Phys. Rev.
IRAC Imaging of Lockman Hole
IRAC imaging of a 4'7x4'7 area in the Lockman Hole detected over 400 galaxies
in the IRAC 3.6 micron and 4.5 micron bands, 120 in the 5.8 micron, and 80 in
the 8 micron bandin 30 minutes of observing time. Color-color diagrams suggest
that about half of these galaxies are at redshifts 0.6<z<1.3 with about a
quarter at higher redshifts (z>1.3). We also detect IRAC counterparts for 6 of
the 7 SCUBA sources and all 9 XMM sources in this area. The detection of the
counterparts of the SCUBA sources and galaxies at z>1.3 demonstrates the
ability of IRAC to probe the universe at very high redshifts.Comment: 11 pages, 2 figures. accepted by ApJS, Spizter Special Issu
The Mid-Infrared Instrument for the James Webb Space Telescope, III: MIRIM, The MIRI Imager
In this article, we describe the MIRI Imager module (MIRIM), which provides
broad-band imaging in the 5 - 27 microns wavelength range for the James Webb
Space Telescope. The imager has a 0"11 pixel scale and a total unobstructed
view of 74"x113". The remainder of its nominal 113"x113" field is occupied by
the coronagraphs and the low resolution spectrometer. We present the instrument
optical and mechanical design. We show that the test data, as measured during
the test campaigns undertaken at CEA-Saclay, at the Rutherford Appleton
Laboratory, and at the NASA Goddard Space Flight Center, indicate that the
instrument complies with its design requirements and goals. We also discuss the
operational requirements (multiple dithers and exposures) needed for optimal
scientific utilization of the MIRIM.Comment: 29 pages, 9 figure
Update to the Vitamin C, Thiamine and Steroids in Sepsis (VICTAS) protocol: statistical analysis plan for a prospective, multicenter, double-blind, adaptive sample size, randomized, placebo-controlled, clinical trial.
BACKGROUND: Observational research suggests that combined therapy with Vitamin C, thiamine and hydrocortisone may reduce mortality in patients with septic shock.
METHODS AND DESIGN: The Vitamin C, Thiamine and Steroids in Sepsis (VICTAS) trial is a multicenter, double-blind, adaptive sample size, randomized, placebo-controlled trial designed to test the efficacy of combination therapy with vitamin C (1.5 g), thiamine (100 mg), and hydrocortisone (50 mg) given every 6 h for up to 16 doses in patients with respiratory or circulatory dysfunction (or both) resulting from sepsis. The primary outcome is ventilator- and vasopressor-free days with mortality as the key secondary outcome. Recruitment began in August 2018 and is ongoing; 501 participants have been enrolled to date, with a planned maximum sample size of 2000. The Data and Safety Monitoring Board reviewed interim results at N = 200, 300, 400 and 500, and has recommended continuing recruitment. The next interim analysis will occur when N = 1000. This update presents the statistical analysis plan. Specifically, we provide definitions for key treatment and outcome variables, and for intent-to-treat, per-protocol, and safety analysis datasets. We describe the planned descriptive analyses, the main analysis of the primary end point, our approach to secondary and exploratory analyses, and handling of missing data. Our goal is to provide enough detail that our approach could be replicated by an independent study group, thereby enhancing the transparency of the study.
TRIAL REGISTRATION: ClinicalTrials.gov, NCT03509350. Registered on 26 April 2018
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