Mental health of UK university business students: Relationship with shame, motivation and self-compassion

There is growing awareness of mental health problems among UK business students, which appears to be exacerbated by students’ attitudes of shame toward mental health. This study recruited 138 UK business students and examined the relationship between mental health and shame, and mental health and potential protective factors such as self-compassion and motivation. A significant correlation between each of the constructs was observed and self-compassion was identified as an explanatory variable for mental health. Shame moderated the relationship between self-compassion and mental health. Integrating self-compassion training into business study programs may help to improve the mental health of this student group.N/

A Vision for the CGIAR: Sustainable Agriculture for a Food Secure World

A statement by an external panel appointed by the CGIAR Oversight Committee, and chaired by Gordon Conway. The need for a new, crisp fifteen page statement pointing the way to the future was identified at MTM92. A draft was discussed at MTM94. The completed version was available at ICW94, and was presented to the Ministerial-Level Meeting at Lucerne in January 1995

On the Photometric Accuracy of RHESSI Imaging and Spectrosocopy

We compare the photometric accuracy of spectra and images in flares observed with the Ramaty High Energy Solar Spectroscopic Imager (RHESSI)}spacecraft. We test the accuracy of the photometry by comparing the photon fluxes obtained in different energy ranges from the spectral-fitting software SPEX with those fluxes contained in the images reconstructed with the Clean, MEM, MEM-Vis, Pixon, and Forward-fit algorithms. We quantify also the background fluxes, the fidelity of source geometries, and spatial spectra reconstructed with the five image reconstruction algorithms. We investigate the effects of grid selection, pixel size, field-of-view, and time intervals on the quality of image reconstruction. The detailed parameters and statistics are provided in an accompanying CD-ROM and web page. We find that Forward-fit, Pixon, and Clean have a robust convergence behavior and a photometric accuracy in the order of a few percents, while MEM does not converge optimally for large degrees of freedom (for large field-of-views and/or small pixel sizes), and MEM-Vis suffers in the case of time-variable sources. This comparative study documents the current status of the RHESSI spectral and imaging software, one year after launch.Comment: 2 Figures, full version on http://www.lmsal.com/~aschwand/eprints/2003_photo/index.htm

Knots with unknotting number 1 and essential Conway spheres

For a knot K in S^3, let T(K) be the characteristic toric sub-orbifold of the orbifold (S^3,K) as defined by Bonahon and Siebenmann. If K has unknotting number one, we show that an unknotting arc for K can always be found which is disjoint from T(K), unless either K is an EM-knot (of Eudave-Munoz) or (S^3,K) contains an EM-tangle after cutting along T(K). As a consequence, we describe exactly which large algebraic knots (ie algebraic in the sense of Conway and containing an essential Conway sphere) have unknotting number one and give a practical procedure for deciding this (as well as determining an unknotting crossing). Among the knots up to 11 crossings in Conway's table which are obviously large algebraic by virtue of their description in the Conway notation, we determine which have unknotting number one. Combined with the work of Ozsvath-Szabo, this determines the knots with 10 or fewer crossings that have unknotting number one. We show that an alternating, large algebraic knot with unknotting number one can always be unknotted in an alternating diagram. As part of the above work, we determine the hyperbolic knots in a solid torus which admit a non-integral, toroidal Dehn surgery. Finally, we show that having unknotting number one is invariant under mutation.Comment: This is the version published by Algebraic & Geometric Topology on 19 November 200

The concordance genus of knots

In knot concordance three genera arise naturally, g(K), g_4(K), and g_c(K): these are the classical genus, the 4-ball genus, and the concordance genus, defined to be the minimum genus among all knots concordant to K. Clearly 0 <= g_4(K) <= g_c(K) <= g(K). Casson and Nakanishi gave examples to show that g_4(K) need not equal g_c(K). We begin by reviewing and extending their results. For knots representing elements in A, the concordance group of algebraically slice knots, the relationships between these genera are less clear. Casson and Gordon's result that A is nontrivial implies that g_4(K) can be nonzero for knots in A. Gilmer proved that g_4(K) can be arbitrarily large for knots in A. We will prove that there are knots K in A with g_4(K) = 1 and g_c(K) arbitrarily large. Finally, we tabulate g_c for all prime knots with 10 crossings and, with two exceptions, all prime knots with fewer than 10 crossings. This requires the description of previously unnoticed concordances.Comment: Published by Algebraic and Geometric Topology at http://www.maths.warwick.ac.uk/agt/AGTVol4/agt-4-1.abs.htm

User Experiences of an Electronic Personal Health Record for Diabetes

Background: My Diabetes My Way (MDMW) is an electronic personal health record (ePHR) that provides access to educational resources and clinical data to people with diabetes in Scotland. This questionnaire study aims to assess user experience, barriers to access, and inform future development.Methods: All active MDMW users (n = 3797) were invited to complete an online questionnaire in May 2015, surveying usage patterns and system utility. A “utility score” was calculated, based on responses to Likert-scale questions and used as the dependent variable within regression analysis, with demographic features as independent predictors. Free-text responses were analyzed thematically and presented using descriptive statistics.Results: A total of 1095/3797 (27.5%) active users completed the survey. Of them, 690/1095 (63%) were male. There was representation of all age and socioeconomic groups. Respondents were positive regarding the system utility, which met expectations. The majority of respondents believed that online access to diabetes information has the potential to improve diabetes self-care within the population. The most valued features were personal clinical data associated visualizations. The main problems cited were data accuracy and system access (ie, log-in procedure). Perceived usefulness of the system was inversely associated with duration of diabetes, which was the only significant predictor of utility score.Conclusions: This study has demonstrated that MDMW users find the system useful in supporting diabetes self-management. The system was found to have greatest utility among those most recently diagnosed with diabetes. This study has informed further development of the service, including enhancing data visualization and the need to improve access to the system

My Diabetes My Way:supporting online diabetes self-management: progress and analysis from 2016

Abstract Background My Diabetes My Way (MDMW) is the National Health Service (NHS) Scotland website for people with diabetes and their carers. It consists of an interactive information website and an electronic personal health record (ePHR) available to the 291,981 people with diabetes in Scotland. We aimed to analyse the demographic characteristics of current registrants and system usage and activity during 2016. Methods We analysed system audit trails to monitor user activity and page accesses on the information website, and logins and activity within the ePHR. The ePHR contains data from SCI-Diabetes, NHS Scotland’s flagship diabetes record, sourcing data from primary and secondary care, specialist screening services and laboratory systems. We reviewed patient registration characteristics to collate demographic data for the MWDH cohort, then compared this to aggregate data published in the 2016 Scottish Diabetes Survey. The Scottish Diabetes Survey is an annual population-based report detailing diabetes statistics for the whole diabetes population in NHS Scotland. Results The MDMW information website received an average of 101,382 page accesses per month during 2016 (56.9% increase from 2015; n = 64,607). ePHR registrants were more likely to be younger (p < 0.001) and have an ethnicity of “white” (p < 0.001) than the background diabetes population. At the end of 2016, 11,840 people with diabetes had accessed their personal clinical information (58.6% increase since end 2015; n = 7464). During 2016, an average of 1907 people accessed their records each month (48.3% increase from 2015; n = 1286). Conclusion My Diabetes My Way is a useful tool aid to diabetes self-management. The service is unique in offering records access to a national population, providing information from all relevant diabetes-related sources, rather than a single silo. MDMW supports the diabetes improvement, self-management, healthcare quality and eHealth strategies of the Scottish Government. The service also has potential to be adapted to work with other clinical systems and conditions

Water for small-scale biogas digesters in sub-Saharan Africa

Acknowledgements This work was part-funded by the UK Natural Environment Research Council funded ESPA project, NE/K010441/1 ‘ALTER – Alternative Carbon Investments in Ecosystems for Poverty Alleviation’. We are also grateful to the AUC for funding part of this work under the Afri-Flame project on ‘Adapta- tion of small-scale biogas digesters for use in rural households in sub-Saharan AfricaPeer reviewedPublisher PD

Comparison of genomic signatures of selection on Plasmodium falciparum between different regions of a country with high malaria endemicity.

BACKGROUND: Genome wide sequence analyses of malaria parasites from widely separated areas of the world have identified contrasting population structures and signatures of selection. To compare relatively closely situated but ecologically contrasting regions within an endemic African country, population samples of Plasmodium falciparum clinical isolates were collected in Ghana from Kintampo in the central forest-savannah area, and Navrongo in a drier savannah area ~350 km to the north with more seasonally-restricted transmission. Parasite DNA was sequenced and paired-end reads mapped to the P. falciparum reference genome. RESULTS: High coverage genome wide sequence data for 85 different clinical isolates enabled analysis of 121,712 single nucleotide polymorphisms (SNPs). The local populations had similar proportions of mixed genotype infections, similar SNP allele frequency distributions, and eleven chromosomal regions had elevated integrated haplotype scores (|iHS|) in both. A between-population Rsb metric comparing extended haplotype homozygosity indicated a stronger signal within Kintampo for one of these regions (on chromosome 14) and in Navrongo for two of these regions (on chromosomes 10 and 13). At least one gene in each of these identified regions is a potential target of locally varying selection. The candidates include genes involved in parasite development in mosquitoes, members of variant-expressed multigene families, and a leading vaccine-candidate target of immunity. CONCLUSIONS: Against a background of very similar population structure and selection signatures in the P. falciparum populations of Ghana, three narrow genomic regions showed evidence indicating local differences in historical timing or intensity of selection. Sampling of closely situated populations across heterogeneous environments has potential to refine the mapping of important loci under temporally or spatially varying selection