Efficient Quantum Circuits for Schur and Clebsch-Gordan Transforms

The Schur basis on n d-dimensional quantum systems is a generalization of the total angular momentum basis that is useful for exploiting symmetry under permutations or collective unitary rotations. We present efficient (size poly(n,d,log(1/\epsilon)) for accuracy \epsilon) quantum circuits for the Schur transform, which is the change of basis between the computational and the Schur bases. These circuits are based on efficient circuits for the Clebsch-Gordan transformation. We also present an efficient circuit for a limited version of the Schur transform in which one needs only to project onto different Schur subspaces. This second circuit is based on a generalization of phase estimation to any nonabelian finite group for which there exists a fast quantum Fourier transform.Comment: 4 pages, 3 figure

Symmetric coupling of four spin-1/2 systems

We address the non-binary coupling of identical angular momenta based upon the representation theory for the symmetric group. A correspondence is pointed out between the complete set of commuting operators and the reference-frame-free subsystems. We provide a detailed analysis of the coupling of three and four spin-1/2 systems and discuss a symmetric coupling of four spin-1/2 systems.Comment: 20 pages, no figure

Lensless Fourier-Transform Ghost Imaging with Classical Incoherent Light

The Fourier-Transform ghost imaging of both amplitude-only and pure-phase objects was experimentally observed with classical incoherent light at Fresnel distance by a new lensless scheme. The experimental results are in good agreement with the standard Fourier-transform of the corresponding objects. This scheme provides a new route towards aberration-free diffraction-limited 3D images with classically incoherent thermal light, which have no resolution and depth-of-field limitations of lens-based tomographic systems.Comment: 14 pages, 4 figures, comments are welcom

Modelling Collision Products of Triple-Star Mergers

In dense stellar clusters, binary-single and binary-binary encounters can ultimately lead to collisions involving two or more stars. A comprehensive survey of multi-star collisions would need to explore an enormous amount of parameter space, but here we focus on a number of representative cases involving low-mass main-sequence stars. Using both Smoothed Particle Hydrodynamics (SPH) calculations and a much faster fluid sorting software package (MMAS), we study scenarios in which a newly formed product from an initial collision collides with a third parent star. By varying the order in which the parent stars collide, as well as the orbital parameters of the collision trajectories, we investigate how factors such as shock heating affect the chemical composition and structure profiles of the collision product. Our simulations and models indicate that the distribution of most chemical elements within the final product is not significantly affected by the order in which the stars collide, the direction of approach of the third parent star, or the periastron separations of the collisions. We find that the sizes of the products, and hence their collisional cross sections for subsequent encounters, are sensitive to the order and geometry of the collisions. For the cases that we consider, the radius of the product formed in the first (single-single star) collision ranges anywhere from roughly 2 to 30 times the sum of the radii of its parent stars. The final product formed in our triple-star collisions can easily be as large or larger than a typical red giant. We therefore expect the collisional cross section of a newly formed product to be greatly enhanced over that of a thermally relaxed star of the same mass.Comment: 20 pages, submitted to MNRA

Boceprevir for untreated chronic HCV genotype 1 infection.

International audienceBACKGROUND: Peginterferon-ribavirin therapy is the current standard of care for chronic infection with hepatitis C virus (HCV). The rate of sustained virologic response has been below 50% in cases of HCV genotype 1 infection. Boceprevir, a potent oral HCV-protease inhibitor, has been evaluated as an additional treatment in phase 1 and phase 2 studies. METHODS: We conducted a double-blind study in which previously untreated adults with HCV genotype 1 infection were randomly assigned to one of three groups. In all three groups, peginterferon alfa-2b and ribavirin were administered for 4 weeks (the lead-in period). Subsequently, group 1 (the control group) received placebo plus peginterferon-ribavirin for 44 weeks; group 2 received boceprevir plus peginterferon-ribavirin for 24 weeks, and those with a detectable HCV RNA level between weeks 8 and 24 received placebo plus peginterferon-ribavirin for an additional 20 weeks; and group 3 received boceprevir plus peginterferon-ribavirin for 44 weeks. Nonblack patients and black patients were enrolled and analyzed separately. RESULTS: A total of 938 nonblack and 159 black patients were treated. In the nonblack cohort, a sustained virologic response was achieved in 125 of the 311 patients (40%) in group 1, in 211 of the 316 patients (67%) in group 2 (P<0.001), and in 213 of the 311 patients (68%) in group 3 (P<0.001). In the black cohort, a sustained virologic response was achieved in 12 of the 52 patients (23%) in group 1, in 22 of the 52 patients (42%) in group 2 (P=0.04), and in 29 of the 55 patients (53%) in group 3 (P=0.004). In group 2, a total of 44% of patients received peginterferon-ribavirin for 28 weeks. Anemia led to dose reductions in 13% of controls and 21% of boceprevir recipients, with discontinuations in 1% and 2%, respectively. CONCLUSIONS: The addition of boceprevir to standard therapy with peginterferon-ribavirin, as compared with standard therapy alone, significantly increased the rates of sustained virologic response in previously untreated adults with chronic HCV genotype 1 infection. The rates were similar with 24 weeks and 44 weeks of boceprevir

Dynamical Processes in Globular Clusters

Globular clusters are among the most congested stellar systems in the Universe. Internal dynamical evolution drives them toward states of high central density, while simultaneously concentrating the most massive stars and binary systems in their cores. As a result, these clusters are expected to be sites of frequent close encounters and physical collisions between stars and binaries, making them efficient factories for the production of interesting and observable astrophysical exotica. I describe some elements of the competition among stellar dynamics, stellar evolution, and other processes that control globular cluster dynamics, with particular emphasis on pathways that may lead to the formation of blue stragglers.Comment: Chapter 10, in Ecology of Blue Straggler Stars, H.M.J. Boffin, G. Carraro & G. Beccari (Eds), Astrophysics and Space Science Library, Springe

Effect of insulin on carbon dioxide production in adipose tissue from immature rats

Es wurde der Einfluss von Insulin auf die CO 2 -Produktion im Fettgewebe unreifer Ratten mit einem Gewicht zwischen 35 und 90 g manometrisch bestimmt, wobei mit zunehmendem Gewicht bis zu 90 g eine vermehrte CO 2 -Produktion festgestellt werden konnte.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/42239/1/18_2005_Article_BF02142277.pd

Positive and negative evaluation of caregiving among three different types of informal care relationships

Based on the caregiver stress model, we examined how care demands, caregiver motivation, coping style and external support are associated with positive evaluation and caregiver burden among spousal, adult child and other types of care relations. Data from a sample of Dutch informal caregivers of 1,685 older persons (55 and older) were analyzed employing multivariate linear regression analyses for each of the care relationship types. Spouses (N = 206) report high positive evaluation and high burden, adult children (N = 1,093) report low positive evaluation, and other caregivers (N = 386) report high positive evaluation and a low burden. Multivariate linear regression analyses showed that motives and external support were important for positive evaluation but the impact varied among types of caregivers, whereas care demands and not asking for help were associated with burden for all types. Only among 'other' caregiver relationships, positive evaluation was negatively associated with burden. It is concluded that results confirm the dual nature of caregiving among spouses and children. The care context and motivation of the different types of caregivers explain their differences in care evaluation. Various interventions for types of caregivers are discussed. © 2013 Springer-Verlag Berlin Heidelberg

Materiality, health informatics and the limits of knowledge production

© IFIP International Federation for Information Processing 2014 Contemporary societies increasingly rely on complex and sophisticated information systems for a wide variety of tasks and, ultimately, knowledge about the world in which we live. Those systems are central to the kinds of problems our systems and sub-systems face such as health and medical diagnosis, treatment and care. While health information systems represent a continuously expanding field of knowledge production, we suggest that they carry forward significant limitations, particularly in their claims to represent human beings as living creatures and in their capacity to critically reflect on the social, cultural and political origins of many forms of data ‘representation’. In this paper we take these ideas and explore them in relation to the way we see healthcare information systems currently functioning. We offer some examples from our own experience in healthcare settings to illustrate how unexamined ideas about individuals, groups and social categories of people continue to influence health information systems and practices as well as their resulting knowledge production. We suggest some ideas for better understanding how and why this still happens and look to a future where the reflexivity of healthcare administration, the healthcare professions and the information sciences might better engage with these issues. There is no denying the role of health informatics in contemporary healthcare systems but their capacity to represent people in those datascapes has a long way to go if the categories they use to describe and analyse human beings are to produce meaningful knowledge about the social world and not simply to replicate past ideologies of those same categories

Stellar Collisions During Binary-Binary and Binary-Single Star Interactions

Physical collisions between stars occur frequently in dense star clusters, either via close encounters between two single stars, or during strong dynamical interactions involving binary stars. Here we study stellar collisions that occur during binary-single and binary-binary interactions, by performing numerical scattering experiments. Our results include cross sections, branching ratios, and sample distributions of parameters for various outcomes. For interactions of hard binaries containing main-sequence stars, we find that the normalized cross section for at least one collision to occur (between any two of the four stars involved) is essentially unity, and that the probability of collisions involving more than two stars is significant. Hydrodynamic calculations have shown that the effective radius of a collision product can be 2-30 times larger than the normal main-sequence radius for a star of the same total mass. We study the effect of this expansion, and find that it increases the probability of further collisions considerably. We discuss these results in the context of recent observations of blue stragglers in globular clusters with masses exceeding twice the main-sequence turnoff mass. We also present Fewbody, a new, freely available numerical toolkit for simulating small-N gravitational dynamics that is particularly suited to performing scattering experiments.Comment: Accepted for publication in MNRAS; 29 pages, 22 figures, 7 table