Patohistološke lezije u običnog jelena (Cervus elaphus) iz mjesta Idanha-a-Nova i Lousã (Portugal): preliminarni rezultati

The red deer (Cervus elaphus) is a wild ungulate and game species with a broad distribution in Portugal. In Idanha-a-Nova (Castelo Branco) there is a particular interest in studying these populations due to the importance of the hunting industry to the regional economy, and the recognised role of ungulates as reservoirs of infectious agents to livestock and humans. This histopathology survey aimed to compare deer lesions from Idanha-a-Nova (n=16) and Lousã (n=4). Samples from the lung, liver and kidney of animals were collected during the hunting season. The results reveal a high prevalence of parasitic bronchitis (13/20; 65%), especially in Idanha-a-Nova (11/16; 68.8%). Moreover, many animals presented non-purulent nephritis (8/20; 40%). No statistically significant differences were found between regions or genders for any lesion. This survey provides an overview of the health status of the red deer populations in these regions. Further studies are crucial to better know the sanitary situation of these populations and under the One Health perspective, to apply protective measures for animal, hunter and consumer health.Obični je jelen (Cervus elaphus) divlji kopitar i vr- sta divljači koja je vrlo raširena u Portugalu. U mjestu Idanha-a-Nova (Castelo Branco) postoji poseban in- teres za istraživanje ovih populacija uslijed važnosti lovne industrije za regionalnu ekonomiju, uz pre- poznatu ulogu kopitara kao rezervoara uzročnika infekcija stoke i ljudi. Ovaj smo patohistološki pre- gled pisali s ciljem usporedbe lezije jelena iz mjesta Idanha-a-Nova (n=16) i Lousã (n=4). Tijekom sezone lova prikupljeni su uzorci iz pluća, jetre i bubrega svih životinja. Rezultati su otkrili veliku prevalenciju bronhitisa prouzročenog parazitima (13/20; 65 %), posebno u mjestu Idanha-a-Nova (11/16; 68,8 %), a brojne životinje su imale i negnojni nefritis (8/20; 40 %). Nisu otkrivene nikakve statistički značajne raz- like između regija i spolova za bilo koju leziju. Ova studija daje pregled zdravstvenog statusa populacije običnog jelena u tim regijama. Dodatne studije su ključne za bolje poznavanje zdravstvenih prilika tih populacija, iz perspektive Jednog zdravlja, u svrhu poduzimanja mjera zaštite zdravlja potrošča, lovaca i životinja

La válvula cardiaca de Álvarez

[ES] Una válvula de disco para sustitución de la válvula mitral fue diseñada en 1964 por el cirujano cardiovascular español Francisco Alvarez. La prótesis se implantó en España y en Inglaterra hasta 1967. Las complicaciones tromboembólicas surgidas aconsejaron la interrupción de su aplicaciónS

Anatomy and imaging of rat prostate: practical monitoring in experimental cancer-induced protocols

The rat has been frequently used as a model to study several human diseases, including cancer. In many research protocols using cancer models, researchers find it difficult to perform several of the most commonly used techniques and to compare their results. Although the protocols for the study of carcinogenesis are based on the macroscopic and microscopic anatomy of organs, few studies focus on the use of imaging. The use of imaging modalities to monitor the development of cancer avoids the need for intermediate sacrifice to assess the status of induced lesions, thus reducing the number of animals used in experiments. Our work intends to provide a complete and systematic overview of rat prostate anatomy and imaging, facilitating the monitoring of prostate cancer development through different imaging modalities, such as ultrasonography, computed tomography (CT) and magnetic resonance imaging (MRI).publishe

Estudio de los efectos de las lesiones del labrum acetabular en la cadera en un modelo experimental lagomorfo adulto

Objetivo: El cartílago labral es una estructura cartilaginosa que recubre el acetábulo de la cadera. Su lesión es controvertida en cuanto a sus implicaciones debido a que no se conoce bien si es una causa de degeneración articular o sólo un cambio degenerativo más. Hemos diseñado un modelo animal en conejo para estudiar esta lesión. Material y metodología: Se utilizaron tres grupos de 13 animales a los que se lesionó una cadera dejando la otra como control y se les mantuvo estabulados al primer grupo 12 semanas, al segundo 18 y al tercero 30. Posteriormente se les realizó un estudio radiológico, otro por resonancia magnética y, tras su sacrificio, un estudio histológico. Resultados: No encontramos relación en nuestro modelo entre la lesión labral y los cambios degenerativos posteriores en los plazos citados. Tampoco encontramos daños labrales sin cicatrizar en el momento del sacrificio. Conclusión: En el modelo animal lagomorfo, la lesión labral no produce cambios degenerativos artrósicos y el cartílago labral podría presentar cierta capacidad de regeneración

Role of age and comorbidities in mortality of patients with infective endocarditis

[Purpose]: The aim of this study was to analyse the characteristics of patients with IE in three groups of age and to assess the ability of age and the Charlson Comorbidity Index (CCI) to predict mortality. [Methods]: Prospective cohort study of all patients with IE included in the GAMES Spanish database between 2008 and 2015.Patients were stratified into three age groups:<65 years,65 to 80 years,and ≥ 80 years.The area under the receiver-operating characteristic (AUROC) curve was calculated to quantify the diagnostic accuracy of the CCI to predict mortality risk. [Results]: A total of 3120 patients with IE (1327 < 65 years;1291 65-80 years;502 ≥ 80 years) were enrolled.Fever and heart failure were the most common presentations of IE, with no differences among age groups.Patients ≥80 years who underwent surgery were significantly lower compared with other age groups (14.3%,65 years; 20.5%,65-79 years; 31.3%,≥80 years). In-hospital mortality was lower in the <65-year group (20.3%,<65 years;30.1%,65-79 years;34.7%,≥80 years;p < 0.001) as well as 1-year mortality (3.2%, <65 years; 5.5%, 65-80 years;7.6%,≥80 years; p = 0.003).Independent predictors of mortality were age ≥ 80 years (hazard ratio [HR]:2.78;95% confidence interval [CI]:2.32–3.34), CCI ≥ 3 (HR:1.62; 95% CI:1.39–1.88),and non-performed surgery (HR:1.64;95% CI:11.16–1.58).When the three age groups were compared,the AUROC curve for CCI was significantly larger for patients aged <65 years(p < 0.001) for both in-hospital and 1-year mortality. [Conclusion]: There were no differences in the clinical presentation of IE between the groups. Age ≥ 80 years, high comorbidity (measured by CCI),and non-performance of surgery were independent predictors of mortality in patients with IE.CCI could help to identify those patients with IE and surgical indication who present a lower risk of in-hospital and 1-year mortality after surgery, especially in the <65-year group

The Alvarez cardiac prosthesis

A prosthetic disc valve for the mitral position was designed by the Spanish cardiovascular surgeon Francisco Alvarez in 1964. The valve was inserted in Spain and in the United Kingdom until 1967. Multiple thromboembolic complications stopped its application

Wild Boars (<i>Sus scrofa</i>, L. 1758) from Castile and Leon Region (Spain): A Histopathology Survey

Wild boars are wild ungulates with a wide distribution in Europe, with a relevant role in wildlife and public health. In Spain, high (and sometimes artificial) densities of wild boars are responsible for several health problems. Regular surveys, with hunters’ collaboration, are crucial to monitor these diseases. Histological analyses were performed for lung, liver, and kidneys from 72 wild boars (58 from Zamora, 16 from Palencia). Lungs were the most affected organs, mainly revealing parasitic pneumonia (34.7%). Hydropic, vacuolar, and other cellular changes (33.3%) and congestion (16.7%) were found in the liver, and only 30.6% of the wild boars presented no alterations in this organ. Regarding the kidney, non-purulent nephritis (22.2%) was the most common lesion. This study gives an overview of the health status of wild boar populations in Castile and León. Other laboratory analyses are needed to obtain definitive diagnoses of these lesions, reach other conclusions, or apply any mitigation strategies to protect animals’ or consumers’ health

Cross-section topographical anatomy of dolphins and its application for diagnosis imaging techniques

21th Annual Conference of the European Cetacean Society and Associated Workshops, April 23-25, 2007, Donostia-San SebastiánNowadays, the diagnostic imaging techniques: ultrasound, computed tomography (CT) and magnetic resonance (MR) are increasingly being used by veterinary practitioners. Its specific use in marine species has been limited due to a number of factors, particularly the scarcity of bidimensional topographical anatomy studiesN

High Levels of Heavy Metal(loid)s Related to Biliary Hyperplasia in Hedgehogs (<i>Erinaceus europaeus</i>)

Heavy metal(loid) pollution of ecosystems is a current One Health problem. The liver is one of the most affected organs in cases of acute or chronic exposure to abnormal amounts of these substances, inducing histopathologic lesions. In order to assess the influence of heavy metal(loids), forty-five European hedgehogs (Erinaceus europaeus) were submitted to necropsy, and liver samples were collected for a routine histopathology exam and metal(loid)s determination (As, Cd, Co, Cr, Cu and Pb) by ICP-MS. Age was estimated during the necropsy exam. Biliary hyperplasia was the most frequent lesion observed (16/45; 35.56%). No statistically significant associations were found between biliary hyperplasia and age or sex. Metal(loid)s’ concentrations were higher in animals with biliary hyperplasia (except for As). There was a statistically significant difference for both Cd and Co. For As, Cd and Co, cubs and juveniles animals showed significantly lower concentrations than elder individuals. Only for Pb were significant differences found between females and males. As described in the literature, exposure to metal(loid)s may be a cause of biliary hyperplasia, although further research (including the use of biochemical methods) is needed to support these results. To the authors’ knowledge, this is the first report of this association in hedgehogs