337 research outputs found

    Análisis espacial del patio en la vivienda mexicalense

    Get PDF
    Peer Reviewe

    VOCES DE LAS ENFERMERAS AL PERCIBIR EL DOLOR DEL PACIENTE INFANTIL QUEMADO

    Get PDF
    El objetivo del estudio fue revelar la percepción de la enfermera frente al dolor nociceptivo del paciente infantil que sufre quemaduras. Desarrollado en un hospital pediátrico del Distrito Federal, México. Investigación cualitativa, de tipo descriptivo. Para la recolección se aplicó una guía de entrevista semiestructurada a diez enfermeras del área de quemados, siendo los datos analizados mediante análisis de contenido. Como resultados se obtuvieron tres categorías. Se utilizó como referencial teórico la fenomenología. Los resultados muestran las vivencias de las enfermeras, la expresión, del mecanismos de conducta auto-defensiva, en la percepción de sus intervenciones, se destaca la carga humanística que tienen las emociones, pues el hecho de manifestarlas implica un gasto extra de fuerza y energía, resultando que a mayor intensidad de la emoción a la que se enfrentan, más es el trabajo emocional que realizan. En conclusión el sujeto aprende las vivencias del yo por medio de la experiencia

    The nurse’s humanistic functioning in relation to the pain of the child patient with burns

    Get PDF
    El artículo tiene como objetivo reflejar sobre la actuación humanística de la enfermera en la intervención del dolor nociceptivo somático de los niños. Fue realizado un estudio cualitativo descriptivo direccionado y discutido de acuerdo con la fenomenología de Husserl, Se consideraron los aspectos ético-legales, fueron entrevistadas diez enfermeras expertas en área de quemados; los datos relevantes fueron seleccionados por la técnica colorimétrica, para después efectuar un análisis de contenido. Los resultados revelaron que la enfermera es una profesional que actúa afectivamente en situaciones de angustia, tristeza, protegiendo de manera solidaria al paciente infantil, también que las terapias no farmacológicas como la ludoterapia, risoterapia, musicoterapia, ejercicios de relajación, respiración y apoyo psicológico coadyuvan en el combate del dolor. Al concluir se reflejó que la intervención de la enfermera es altamente humanística, y se revela que el dolor requiere ser tratado por profesionales con amplia sensibilidad para brindar cuidado altamente humano.This article aims to reflect on the humanistic functioning of the nurse in the interventions with nociceptive, somatic pain in children. To this end a qualitative descriptive study was undertaken, directed and discussed in accordance with Husserlian phenomenology. Ethical-legal aspects were taken into consideration, interviews being held with 10 nurses who are specialists in the area of burns. The relevant data were selected through the colorimetric technique, so as to later undertake content analysis. The results revealed the nurse to be a professional who acts affectively in situations of distress and sadness, protecting the child patient empathetically. In addition, it is possible to perceive that non-pharmacological therapies, such as play therapy, laughter therapy, music therapy, relaxation exercises, breathing exercises, and psychological support are coadjuvant in combating pain. At the end of the study, it is reflected that the nurse’s intervention is highly humanistic, and it is shown that pain must be treated by professionals with great sensitivity, so as to promote highly humane car

    Sub-micro- and nano-sized polyethylene terephthalate deconstruction with engineered protein nanopores

    Get PDF
    The identification or design of biocatalysts to mitigate the accumulation of plastics, including sub-micro- and nano-sized polyethylene terephthalate (nPET), is becoming a global challenge. Here we computationally incorporated two hydrolytic active sites with geometries similar to that of Idionella sakaiensis PET hydrolase, to fragaceatoxin C (FraC), a membrane pore-forming protein. FraCm1/m2 could be assembled into octameric nanopores (7.0 nm high × 1.6–6.0 nm entry), which deconstructed (40 °C, pH 7.0) nPET from GoodFellow, commodities and plastic bottles. FraCm1 and FraCm2 degrade nPET by endo- and exo-type chain scission. While FraCm1 produces bis(2-hydroxyethyl) terephthalate as the main product, FraCm2 yields a high diversity of oligomers and terephthalic acid. Mechanistic and biochemical differences with benchmark PET hydrolases, along with pore and nPET dynamics, suggest that these pore-forming protein catalytic nanoreactors do not deconstruct macro-PET but are promising in nanotechnology for filtering, capturing and breaking down nPET, for example, in wastewater treatment plants.This study was conducted under the auspices of the FuturEnzyme Project funded by the European Union’s Horizon 2020 Research and Innovation Programme under the auspices of the FuturEnzyme Project (grant agreement no. 101000327) and the PlasticsFatE project (grant agreement no. 95921), and Horizon Europe Research and Innovation Programme under grant agreement no. GA101060625 (Nymphe project). We also acknowledge financial support under grants PID2020-112758RB-I00 (M.F.), PDC2021-121534-I00 (M.F.), TED2021-130544B-I00 (M.F.), PID2019-106370RB-I00 (V.G.) and PID2019-105838RB-C31 (F.J.P.) from the Ministerio de Ciencia e Innovación, Agencia Estatal de Investigación (AEI) (Digital Object Identifier MCIN/AEI/10.13039/501100011033), Fondo Europeo de Desarrollo Regional (ERDF) A way of making Europe and the European Union NextGenerationEU/PRTR, UCM-Banco Santander Grants PR87/19-22556 and PR108/20-26896 and UnaEuropa (Unano) SF2106 (to A.M.P.). S.G.-L. was supported by a Real Colegio Complutense Postdoctoral Fellowship for Distinguished Junior Scholars. S.R. thanks the Spanish Ministry of Science and Innovation for a PhD fellowship (FPU19/00608). D.H.-M. thanks Complutense University of Madrid and Banco Santander for a PhD fellowship (CT82/20/CT83/20). A.R.-M. thanks the Spanish Ministry of Science and Innovation for a PhD fellowship (PRE2020-091825) and the project PID2019-106370RB-I00. We thank M. J. Vicente for the ESI–MS analysis, performed at the Servicio Interdepartamental de Investigación (SIDI) from the Autonomous University of Madrid, Spain.Peer Reviewed"Article signat per 16 autors/es: Ana Robles-Martín, Rafael Amigot-Sánchez, Laura Fernandez-Lopez, Jose L. Gonzalez-Alfonso, Sergi Roda, Víctor Alcolea-Rodriguez, Diego Heras-Márquez, David Almendral, Cristina Coscolín, Francisco J. Plou, Raquel Portela, Miguel A. Bañares, Álvaro Martínez-del-Pozo, Sara García-Linares, Manuel Ferrer & Víctor Guallar"Postprint (published version

    RENTABILIDAD DEL NOGAL PECANERO BAJO SISTEMAS DE PRODUCCIÓN DE MEDIANA TECNOLOGÃA EN DELICIAS, CHIHUAHUA

    Get PDF
    Pecans (Carya Illinoinensis [Wangenh] K. Koch) are a native food of North America and represent a high economic crop value in the north of Mexico, mainly in the state of Chihuahua, the biggest pecan nut producer in this country. The goal of this study was to evaluate the profitability of pecan orchards in the municipality of Delicias, Chihuahua. Some microeconomic and market information from 2008 were collected from pecan growers and specialists through the technique of Experts' Panel. Standard financial analysis and a Monte Carlo simulation model were used to evaluate the probabilities of risk for net cash income (NCI) and return on capital employed (RCE). The NCI obtained was $277,000 and RC 111.7%, indicating that pecan orchards show high profitability when is produced under medium-technology conditions in the municipality of Delicias, Chihuahua.Carya Illinoinensis, production costs, Monte Carlo simulation., Agribusiness,

    Synthesis and characterization of extremely small gold nanoshells, and comparison of their photothermal conversion capacity with gold nanorods

    Get PDF
    The current methods for preparing gold nanoshells (AuNSs) produce shells with a diameter of approximately 40 nm or larger, with a relatively large polydispersity. However, AuNSs with smaller diameters and more monodispersity are better suited for biomedical applications. In this work, we present a modified method for the preparation of AuNSs, based on the use of sacrificial silver nanoparticles (AgNPs). We customized the Lee–Meisel method to prepare small and monodisperse AgNPs that were used as sacrificial nanoparticles to prepare extremely small monodispersed AuNSs with an average diameter from 17 to 25 ± 4 nm. We found that these AuNSs are faceted, and that the oxidized silver likely dissolves out of the nanoparticles through some of the facets on the AuNSs. This leads to a silver oxide plug on the surface of the AuNSs, which has not been reported before. The smaller AuNSs, prepared under the best conditions, absorb in the near infrared region (NIR) that is appropriate for applications, such as photothermal therapy or medical imaging. The AuNSs showed absorption peaks in the NIR similar to those of gold nanorods (AuNRs) but with better photothermal capacity. In addition, because of their negative charge, these AuNSs are more biocompatible than the positively charged AuNRs. The synthesis of small, monodisperse, stable and biocompatible nanoparticles, like the ones presented in this work, is of prime importance in biomedical applications.The current methods for preparing gold nanoshells (AuNSs) produce shells with a diameter of approximately 40 nm or larger, with a relatively large polydispersity. However, AuNSs with smaller diameters and more monodispersity are better suited for biomedical applications. In this work, we present a modified method for the preparation of AuNSs, based on the use of sacrificial silver nanoparticles (AgNPs). We customized the Lee–Meisel method to prepare small and monodisperse AgNPs that were used as sacrificial nanoparticles to prepare extremely small monodispersed AuNSs with an average diameter from 17 to 25 ± 4 nm. We found that these AuNSs are faceted, and that the oxidized silver likely dissolves out of the nanoparticles through some of the facets on the AuNSs. This leads to a silver oxide plug on the surface of the AuNSs, which has not been reported before. The smaller AuNSs, prepared under the best conditions, absorb in the near infrared region (NIR) that is appropriate for applications, such as photothermal therapy or medical imaging. The AuNSs showed absorption peaks in the NIR similar to those of gold nanorods (AuNRs) but with better photothermal capacity. In addition, because of their negative charge, these AuNSs are more biocompatible than the positively charged AuNRs. The synthesis of small, monodisperse, stable and biocompatible nanoparticles, like the ones presented in this work, is of prime importance in biomedical applications

    Dogs Detecting COVID-19 From Sweat and Saliva of Positive People : A Field Experience in Mexico

    Get PDF
    ContextMolecular tests are useful in detecting COVID-19, but they are expensive in developing countries. COVID-19-sniffing dogs are an alternative due to their reported sensitivity (>80%) and specificity (>90%). However, most of the published evidence is experimental, and there is a need to determine the performance of the dogs in field conditions. Hence, we aimed to test the sensitivity and specificity of COVID-19-sniffing dogs in the field. MethodsWe trained four dogs with sweat and three dogs with saliva of COVID-19-positive patients, respectively, for 4.5 months. The samples were obtained from a health center in Hermosillo, Sonora, with the restriction to spend 5 min per patient. We calculated sensitivity, specificity, and their 95% confidence intervals (CI). ResultsTwo sweat-sniffing dogs reached 76 and 80% sensitivity, with the 95% CI not overlapping the random value of 50%, and 75 and 88% specificity, with the 95% CI not overlapping the 50% value. The 95% CI of the sensitivity and specificity of the other two sweat dogs overlapped the 50% value. Two saliva-sniffing dogs had 70 and 78% sensitivity, and the 95% CI of their sensitivity and specificity did not overlap the 50% value. The 95% CI of the third dog's sensitivity and specificity overlapped the 50% value. ConclusionFour of the six dogs were able to detect positive samples of patients with COVID-19, with sensitivity and specificity values significantly different from random in the field. We considered the performance of the dogs promising because it is reasonable to expect that with gauze exposed for a longer time to sweat and saliva of people with COVID-19, their detection capacity would improve. The target is to reach the sensitivity range requested by the World Health Organization for the performance of an antigen test (>= 80% sensitivity, >= 97% specificity). If so, dogs could become important allies for the control of the COVID-19 pandemic, especially in developing countries.Peer reviewe

    Simulation tool for a submersible autonomous system

    Get PDF
    This article explains one of the assignments developed in SIRENA’s project. This project is a collaborative work created and carried out exclusively by students for creating an AUV (Autonomous Underwater Vehicle) powered by solar energy. The following lines summarizes the assignment of simulate the system’s dynamics, using theoretical studies which provides the submersible’s equations.Peer Reviewe

    Aplicaciones de Internet de las Cosas SIPIA6 - Red de Sensores Inalámbricos con IPv6

    Get PDF
    El proyecto consiste en el diseño y validación del comportamiento de una red de sensores inalámbricos en la adquisición de parámetros ambientales de parcelas agrícolas, con acceso de forma nativa a Internet, denominada SIPIA6. Se trata de la continuación de Red SIPIA, actualmente implementada en una parcela agrícola de prueba. La red SIPIA está basada en la norma IEEE 802.15.4, aplicada al entorno agropecuario en el ámbito de agricultura de precisión, con participación de ingenieros e investigadores agrónomos. Gracias a los desarrollos que se han producido en las redes de sensores inalámbricos en los últimos años, especialmente la miniaturización de los dispositivos, han surgido nuevas tendencias en el sector agrícola como la llamada agricultura de precisión. Esta disciplina cubre múltiples prácticas relativas a la múltiple toma de datos para aplicar en la gestión y toma de decisiones de cultivos y animales. Por medio de sensores estratégicamente situados, se realizará un monitoreo de la temperatura y/o la humedad relativa, con el fin de proveer de gran cantidad de datos confiables para la investigación agronómica. La diferencia principal de la Red SIPIA6 es que sus nodos WSN serán visibles desde Internet y accesibles mediante protocolos y procedimientos estándares. El proyecto permitirá, por lo tanto, extender la visibilidad de una red de sensores agrícola y por lo tanto convertir a SIPIA6 en una aplicación de Internet de las CosasEje: Arquitectura, Redes y Sistemas OperativosRed de Universidades con Carreras en Informática (RedUNCI

    Late gadolinium enhancement distribution patterns in non-ischemic dilated cardiomyopathy: Genotype-phenotype correlation.

    Get PDF
    AIMS Late gadolinium enhancement (LGE) is frequently found in patients with dilated cardiomyopathy (DCM), there is little information about its frequency and distribution pattern according to underlying genetic substrate. We sought to describe LGE patterns according to genotype and to analyze the risk of major ventricular arrhythmias (MVA) according to patterns. METHODS AND RESULTS Cardiac magnetic resonance findings and LGE distribution according to genetics was performed in a cohort of 600 DCM patients followed at 20 Spanish centers. After exclusion of individuals with multiple causative gene variants or with variants in infrequent DCM-causing genes, 577 patients (34% females, mean age 53.5 years, LVEF 36.9 ± 13.9%) conformed the final cohort. A causative genetic variant was identified in 219 (38%) patients and 147 (25.5%) had LGE. Significant differences were found comparing LGE patterns between genes (P < 0.001). LGE was absent or rare in patients with variants in TNNT2, RBM20 and MYH7 (0%, 5% and 20%, respectively). Patients with variants in DMD, DSP and FLNC showed predominance of LGE subepicardial pattern (50%, 41% and 18%, respectively) whereas patients with variants in TTN, BAG3, LMNA and MYBPC3 showed unspecific LGE patterns. Genetic yield differed according to LGE pattern. Patients with subepicardial, lineal midwall, transmural, right ventricular insertion points or with combination of LGE patterns showed increased risk of MVA compared with patients without LGE. CONCLUSION LGE patterns in DCM has a specific distribution according to the affected gene. Certain LGE patterns are associated with increased risk of MVA and with increased yield of genetic testing.This study has been funded by Instituto Salud Carlos III (ISCIII) through the projects ‘PI18/0004, PI19/01283, and PI20/0320’ (co-funded by the European Regional Development Fund/European Social Fund ‘A way to make Europe’/‘Investing in your future’). The Hospital Universitario Puerta de Hierro, the Hospital Universitario Vall Hebrón, the Hospital General Universitario Gregorio Marañón, and the Hospital Universitario Virgen de la Arrixaca are members of the European Reference Network for Rare, Low Prevalence, and Complex Diseases of the Heart (ERN GUARD-Heart). F.d.F. receives grant support from ISCIII (CM20/00101). R.B. receives funding from the Obra Social la Caixa Foundation. M.B. receives funding from ISCIII (PI19/01283). The CNIC is supported by the ISCIII, Ministerio de Ciencia e Innovación of the Spanish Government (MCIN), and Pro CNIC Foundation.S
    corecore