353 research outputs found
Self-referencing spectral interferometric probing of the onset time of relativistic transparency in intense laser-foil interactions
Irradiation of an ultrathin foil target by a high intensity laser pulse drives collective electron motion and the generation of strong electrostatic fields, resulting in ultrabright sources of high-order harmonics and energetic ions. The ion energies can be significantly enhanced if the foil undergoes relativistic self-induced transparency during the interaction, with the degree of enhancement depending in part on the onset time of transparency. We report on a simple and effective approach to diagnose the time during the interaction at which the foil becomes transparent to the laser light, providing a route to optically controlling and optimizing ion acceleration and radiation generation. The scheme involves a self-referencing approach to spectral interferometry, in which coherent transition radiation produced at the foil rear interferes with laser light transmitted through the foil. The relative timing of the onset of transmission with respect to the transition radiation generation is determined from spectral fringe spacing and compared to simultaneous frequency-resolved optical gating measurements. The results are in excellent agreement, and are discussed with reference to particle-in-cell simulations of the interaction physics and an analytical model for the onset time of transparency in ultrathin foils
Thermodynamics and dark energy
A significant observational effort has been directed to unveil the nature of
the so-called dark energy. However, given the large number of theoretical
possibilities, it is possible that such a task cannot be performed on the basis
only of the observational data. In this article we discuss some thermodynamic
properties of this energy component by assuming that its constituents are
massless quanta with a general time-dependent equation-of-state parameter
, where and are
constants and may assume different forms. We show that very restrictive
bounds can be placed on the - space when current observational data
are combined with the thermodynamic constraints derived.Comment: 5 pages, 3 figures, LaTe
Validity of the Generalized Second Law of Thermodynamics of the Universe Bounded by the Event Horizon in Holographic Dark Energy Model
In this letter, we investigate the validity of the generalized second law of
thermodynamics of the universe bounded by the event horizon in the holographic
dark energy model. The universe is chosen to be homogeneous and isotropic and
the validity of the first law has been assumed here. The matter in the universe
is taken in the form of non-interacting two fluid system- one component is the
holographic dark energy model and the other component is in the form of dust.Comment: 8 page
High order mode structure of intense light fields generated via a laser-driven relativistic plasma aperture
The spatio-temporal and polarisation properties of intense light is important in wide-ranging topics at the forefront of extreme light-matter interactions, including ultrafast laser-driven particle acceleration, attosecond pulse generation, plasma photonics, high-field physics and laboratory astrophysics. Here, we experimentally demonstrate modifications to the polarisation and temporal properties of intense light measured at the rear of an ultrathin target foil irradiated by a relativistically intense laser pulse. The changes are shown to result from a superposition of coherent radiation, generated by a directly accelerated bipolar electron distribution, and the light transmitted due to the onset of relativistic self-induced transparency. Simulations show that the generated light has a high-order transverse electromagnetic mode structure in both the first and second laser harmonics that can evolve on intra-pulse time-scales. The mode structure and polarisation state vary with the interaction parameters, opening up the possibility of developing this approach to achieve dynamic control of structured light fields at ultrahigh intensities
Observation of Burst Intensification by Singularity Emitting Radiation generated from relativistic plasma with a high-intensity laser
Coherent x-rays via the Burst Intensification by Singularity Emitting Radiation (BISER) mechanism are generated from relativistic plasma in helium gas target. A broad modulation of the BISER spectrum, which is significantly wider than the harmonic order, is observed and characterized. In particular, we found that the modulation period can be as large as 41 eV
Proton acceleration enhanced by a plasma jet in expanding foils undergoing relativistic transparency
Ion acceleration driven by the interaction of an ultraintense (2x10^20 Wcm^-2) laser pulse with an ultrathin (40nm) foil target is experimentally and numerically investigated. Protons accelerated by sheath fields and via laser radiation pressure are angularly separated and identified based on their directionality and signature features (e.g. transverse instabilities) in the measured spatial-intensity distribution. A low divergence, high energy proton component is also detected when the heated target electrons expand and the target becomes relativistically transparent during the interaction. 2D and 3D particle-in-cell (PIC) simulations indicate that under these conditions a plasma jet is formed at the target rear, supported by a self-generated azimuthal magnetic field, which extends into the expanded layer of sheath-accelerated protons. Electrons trapped within this jet are directly accelerated to super-thermal energies by the portion of the laser pulse transmitted through the target. The resulting streaming of the electrons into the ion layers enhances the energy of protons in the vicinity of the jet. Through the addition of a controlled prepulse, the maximum energy of these protons is demonstrated experimentally and numerically to be sensitive to the picosecond rising edge prole of the laser pulse
Dynamical dark energy with a constant vacuum energy density
We present a holographic dark-energy model in which the Newton constant
scales in such a way as to render the vacuum energy density a true
constant. Nevertheless, the model acts as a dynamical dark-energy model since
the scaling of goes at the expense of deviation of concentration of
dark-matter particles from its canonical form and/or of promotion of their mass
to a time-dependent quantity, thereby making the effective equation of state
(EOS) variable and different from -1 at the present epoch. Thus the model has a
potential to naturally underpin Dirac's suggestion for explaining the
large-number hypothesis, which demands a dynamical along with the
creation of matter in the universe. We show that with the aid of observational
bounds on the variation of the gravitational coupling, the effective-field
theory IR cutoff can be strongly restricted, being always closer to the future
event horizon than to the Hubble distance. As for the observational side, the
effective EOS restricted by observation can be made arbitrary close to -1, and
therefore the present model can be considered as a ``minimal'' dynamical
dark-energy scenario. In addition, for nonzero but small curvature
(|\Omega_{k0}| \lsim 0.003), the model easily accommodates a transition
across the phantom line for redshifts z \lsim 0.2 , as mildly favored by the
data. A thermodynamic aspect of the scenario is also discussed.Comment: 14 pages, 2 figures, revised, title modified, references added, to
appear in Phys. Lett.
UK phenomics platform for developing and validating electronic health record phenotypes: CALIBER
Objective: Electronic health records (EHRs) are a rich source of information on human diseases, but the information is variably structured, fragmented, curated using different coding systems, and collected for purposes
other than medical research. We describe an approach for developing, validating, and sharing reproducible
phenotypes from national structured EHR in the United Kingdom with applications for translational research.
Materials and Methods: We implemented a rule-based phenotyping framework, with up to 6 approaches of
validation. We applied our framework to a sample of 15 million individuals in a national EHR data source (population-based primary care, all ages) linked to hospitalization and death records in England. Data comprised continuous measurements (for example, blood pressure; medication information; coded diagnoses, symptoms,
procedures, and referrals), recorded using 5 controlled clinical terminologies: (1) read (primary care, subset of
SNOMED-CT [Systematized Nomenclature of Medicine Clinical Terms]), (2) International Classification of
Diseases–Ninth Revision and Tenth Revision (secondary care diagnoses and cause of mortality), (3) Office of
Population Censuses and Surveys Classification of Surgical Operations and Procedures, Fourth Revision (hospital surgical procedures), and (4) DMþD prescription codes.
Results: Using the CALIBER phenotyping framework, we created algorithms for 51 diseases, syndromes, biomarkers, and lifestyle risk factors and provide up to 6 validation approaches. The EHR phenotypes are curated
in the open-access CALIBER Portal (https://www.caliberresearch.org/portal) and have been used by 40 national
and international research groups in 60 peer-reviewed publications.
Conclusions: We describe a UK EHR phenomics approach within the CALIBER EHR data platform with initial evidence of validity and use, as an important step toward international use of UK EHR data for health research
The utility of the “Arable Weeds and Management in Europe” database: Challenges and opportunities of combining weed survey data at a European scale
Over the last 30 years many studies have surveyed weed vegetation on arable land. The “Arable Weeds and Management in Europe” (AWME) database is a collection of 36 of these surveys and the associated management data. Here we review the challenges associated with combining disparate datasets and explore some of the opportunities for future research that present themselves thanks to the advent of the AWME database.
We present three case studies repeating previously published national scale analyses with data from a larger spatial extent. We demonstrate that i) the standardisation of abundance data to a common measure, prior to the analysis of the combined dataset, has little impact on the outcome of the analyses, ii) the increased length of environmental or management gradients allows for greater confidence in conclusions, iii) the main conclusions of analyses done at different spatial extents remain consistent. These case studies demonstrate the utility of a Europe-wide weed survey database, for clarifying or extending results obtained from studies at smaller scales. This Europe-wide data collection offers many more opportunities for analysis that could not be addressed in smaller datasets; including questions about the effects of climate change, macro-ecological and biogeographical issues related to weed diversity as well as the dominance or rarity of specific weeds in Europe
Annular fast electron transport in silicon arising from low-temperature resistivity
Fast electron transport in Si, driven by ultra-intense laser pulses, is investigated experimentally and via 3D hybrid-PIC simulations. A transition from a Gaussian-like to an annular fast electron beam profile is demonstrated and explained by resistively generated magnetic fields. The results highlight the potential to completely transform the beam transport pattern by tailoring the resistivity-temperature profile at temperatures as low as a few eV
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