6 research outputs found
Tumour-derived extracellular vesicle based vaccines for melanoma treatment
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/05/2023
- Field of study
The interest of extracellular vesicles (EVs) in cancer immunotherapy is increasing every day. EVs are lipid bilayer vesicles released by most cells, which contain the molecular signature of their parent cell. Melanoma-derived EVs present antigens specific to this aggressive type of cancer, but they also exert immunomodulatory and pro- metastatic activity. Until now, most reviews focus on the immunoevasive characteristics of tumour-derived EVs, but do not help to overcome the issues related to them. In this review, we describe isolation methods of EVs from melanoma patients and most interesting markers to oversee their effect if they are used as antigen carriers. We also discuss the methods developed so far to overcome the lack of immunogenicity of melanoma-derived EVs, which includes EV modification or adjuvant co-administration. In summary, we conclude that EVs can be an interesting antigen source for immunotherapy development once EV obtaining is optimised and the understanding of the mechanisms behind their multiple effects is further understood.Open Access funding provided thanks to the CRUE-CSIC agreement with Springer Nature. This work was supported by the Basque Government (ELKARTEK project ONKOtools (KK20/00069), ONKOVAC (2021111042), and Consolidated Groups, IT1448-22). Lorena Gonzalez-Melero thanks the University of the Basque Country (UPV/EHU) for the PhD grant (PIF18-295)
Computational and Experimental Evaluation of the Immune Response of Neoantigens for Personalized Vaccine Design
- Author
- Alonso Alegre Santos
- Asumendi Mallea Aintzane
- Boyano LĂłpez MarĂa Dolores
- Carrasco Pujante José
- GarcĂa MarĂa AsunciĂłn
- GonzĂĄlez Melero Lorena
- HernĂĄndez MartĂn Rosa MarĂa
- Igartua Olaechea Manuela
- Izu Belloso Rosa MarĂa
- Legarreta Solaguren Leire
- Malaina Celada Iker
- Margareto Javier
- MartĂnez de la Fuente MartĂnez Ildefonso Abel
- MartĂnez FernĂĄndez Luis
- PĂ©rez Pinilla MartĂn Blas
- Salvador MartĂnez Aiala
- SĂĄnchez DĂez Ana
- Publication venue
- MDPI
- Publication date
- 26/05/2023
- Field of study
In the last few years, the importance of neoantigens in the development of personalized antitumor vaccines has increased remarkably. In order to study whether bioinformatic tools are effective in detecting neoantigens that generate an immune response, DNA samples from patients with cutaneous melanoma in different stages were obtained, resulting in a total of 6048 potential neoantigens gathered. Thereafter, the immunological responses generated by some of those neoantigens ex vivo were tested, using a vaccine designed by a new optimization approach and encapsulated in nanoparticles. Our bioinformatic analysis indicated that no differences were found between the number of neoantigens and that of non-mutated sequences detected as potential binders by IEDB tools. However, those tools were able to highlight neoantigens over non-mutated peptides in HLA-II recognition (p-value 0.03). However, neither HLA-I binding affinity (p-value 0.08) nor Class I immunogenicity values (p-value 0.96) indicated significant differences for the latter parameters. Subsequently, the new vaccine, using aggregative functions and combinatorial optimization, was designed. The six best neoantigens were selected and formulated into two nanoparticles, with which the immune response ex vivo was evaluated, demonstrating a specific activation of the immune response. This study reinforces the use of bioinformatic tools in vaccine development, as their usefulness is proven both in silico and ex vivo.This work was supported by Basque Government funding (IT456-22; IT1448-22, IT693-22 and IT1524-22; ONKOVAC 2021111042), as well as by the UPV/EHU (GIU20/035; US21/27; US18/21; PIF18/295) and Basque Center of Applied Mathematics (US21/27 and US18/21)
Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries
- Author
- Abad-Motos Ane
- Abbas Ahmed M.
- Abbas Mostafa
- Abbasi Mujeeb
- Abbott Tom
- Abd Karim Muhammad Fairuz Shah
- Abdalaal Ibrahim
- Abdel-Galil Khalid
- Abdelemam Rania
- Abdelgawad Abdalrahman
- Abdelkarim Maryam
- Abdelkhalek Mohamed
- Abdelmageed Abdelfatah
- Abdelmawgoud Sherif
- Abdelmohsen Sarah
- Abdelrahman Ahmed Saber
- Abdelrahman Mostafa
- Abdelwahab Khaled
- Abdou Hossam
- Abdulai Darling Ramatu
- Abdulkhaleq Marwa
- Abdullah Bahiyah
- Abdulsalam Khalifa
- Abdulsalam Shuaib
- Abdur-Rahman Lukman
- Abdus-Salam Rukiyat
- Abdussalam Hameedat Opeyemi
- Abebrese John Tabiri
- Abeldaño Ariel
- Abou-Khalil Jad
- Abou-Taleb Hisham
- Abozid Anwaar
- Abozied Hesham
- Abrate Alberto
- Abu-Zaid Ahmed
- Abubakar Mohammed Kabir
- Abud Burçin
- Abuzaid Mohammed
- Adam Albushra Altayeb
- Adamina Michel
- Adamou Harissou
- Adamu Auwal
- Adamu Kabir Musa
- Adanu Kekeli
- Adebara Idowu
- Adebola Oluwaseyi
- Ademuyiwa Adesoji
- Adeniran Abiodun
- Adepiti Akinfolarin
- Aderogba Adeleke Akeem
- Adesunkanmi Abdulhafiz
- Adeyeye Ademola
- Adisa Adewale
- Adjeso Theophilus Justus Kofi
- Ads Adel Mohamed
- Ads Alaa Mohamed
- Adu-Aryee Nii Armah
- Adumah Collins
- Afzal Irrum
- Agapov Mikhail
- Agarwal Gaurav
- Agarwal Ravi
- Agbeko Anita Eseenam
- Agbeno Evans Kofi
- Agbonrofo Peter
- Agboola Oluseyi
- Aggarwal Gaurav
- Aghadi Ifeanyi
- Aghtarafi Natasha
- Agrawal Amit
- Agresta Ferdinando
- Aguado HĂ©ctor J.
- Aguilera-Arevalo Maria-Lorena
- Aherne Thomas
- Ahmad Aline
- Ahmad Maleeha
- Ahmad Misbahu
- Ahmad Sarwat
- Ahmad Shahzaib
- Ahmad Shoaib
- Ahmed Hayat Tarig Abdelhafiz
- Ahmed Khalid
- Ahmed Sharwany
- Ahmed Shima
- Ahmed Usama
- Aisuodionoe-Shadrach Oseremen
- Aitken Sarah
- Ajenifuja Kayode
- Ajiya Abdulrazak
- Akeel Nouf
- Akin Emrah
- Akinajo Opeyemi
- Akinyemi Tosin
- Akrida Ioanna
- Aktokmakyan Talar Vartanoglu
- Akwaisah Ayoub
- Al Bettar Osama
- Al-Badawi Ismail A.
- Al-Juaifari Maytham
- Al-Khyatt Waleed
- Al-Mallah Abdullah
- Al-Nusairi Ahmed
- Al-Saadi Nina
- Al-Sayaghi Khaled
- Al-Shaiji Tariq
- Al-Shehari Mohammed
- Al-Touny Aiman
- Al-Touny Shimaa A.
- Aladawi Omar
- Aladna Abdallah
- Alali Mahmoud
- Alam Mahmood
- Alam Mohammed Shadrul
- Alarabi Rehab
- Alawneh Yazan
- Alayande Barnabas
- Albanese Erminia
- Albayadi Eslam
- Albdour Maram
- Alconchel Felipe
- Alderazi Amer
- Alegbeleye Bamidele
- Alekberli Tural
- Alemu Misganaw Alemu Adimass
- Alexander Philip
- Alfieri Alex
- Algahtany Khaled
- Algarni Kamal
- Alhamad Ameen
- Alhamid Mohammad
- Alharmi Rawan A. Rahman
- Alharthi Mohammed
- Alhazmi Barrag
- Ali Mohamed Shafi Mahboob
- Ali Stephen
- Alibrahim Hidar
- Aljaaly Hattan
- Aljaiuossi Anas
- Aljanadi Firas
- Aljiffry Murad
- Aljirdabi Noof
- Alkahlan Mohammed
- Alkhalifa Elmustafa
- Alkhatib Sondos
- Alkhatieb Maram
- Allan Anna
- Almarshad Felwa
- Almgla Naser
- Almhimid Ali
- Almiqlash Bushray
- Almoshantaf Mohammad Badr
- Almutairi Abdulmjeed
- Alnsour Abed Alfattah Mahmoud
- Alobied Majd
- Alomar Osama
- Alonso JesĂșs AarĂłn MartĂnez
- Alonso Manuel Diez
- Alonso Nestor Fabian Pedraza
- Alonso Veronica
- Alqallaf Abdullah
- Alqaseer Asma
- Alrayes Bourhan
- Alsefri Maryam
- Alser Osaid
- Alsharif Mohammed
- Alsori Mohamed
- Altaf Abdulmalik
- Altinel Yuksel
- Altiner Saygin
- Altouny Ahmad
- Altun Demet
- Alvarez Natalia
- Alvarez-Lozada Luis Adrian
- Alvi Abdul
- Alwael Athari
- Alwash Mohammed
- Alyami Ziyad
- Alyousef Mohammed
- Alzahrani Saud
- Alzerwi Nasser
- Amin Shivang
- Amir Mohammed
- Ammar Ahmed Siddique
- Ammendola Michele
- Amores Remedios Revilla
- Amrayev Sultan
- Anastasiadou Sofia
- Ancans Guntis
- Anderson Caroline
- Andreani Lorenzo
- Andreotti Dario
- Andreuccetti Jacopo
- Andrianakis Alexandros
- Andro Christophe
- Anesi Alexandre
- Angamuthu Stephen
- Angeles Martina Aida
- Angelico Roberta
- Angelis Fragkiskos
- Angelou Dimitrios
- Angelou Kyveli
- Angulo Victor Pinto
- Anjum Arfa
- Anjum Muhammad Ayyub
- Annicchiarico Alfredo
- Anoldo Pietro
- Ansaloni Luca
- Anthoulakis Christos
- Antonelli Amedeo
- Anwar Mohamed
- Anwar Sumadi Lukman
- Anwer Mariyah
- Anyanwu Lofty-John
- Apostolou Christos
- Apostolou Konstantinos
- Appiah-Kubi Adu
- Aprea Giovanni
- Arbab Hana
- Archer James
- Ardura Francisco
- Aremu Muyiwa
- Arif Tahera
- Arkani Samara
- Armatura Giulia
- Armijos Daniel
- Arnaout Ali
- Arnaoutoglou Eleni
- Arnaud Alexis P.
- Arneja Jugpal
- Arrangoiz Rodrigo
- Arshad Muhammad
- Arthur Joshua
- Ashcroft James
- Ashford Bruce
- Ashraf Fariha
- Asiimwe Daniel
- Asirifi Samuel Amoako
- Asla Amir
- Aslam Ramisha
- Aspide Raffaele
- Ataya Karim
- Ateca Ibabe Villalabeitia
- Atici Semra Demirli
- Atis Gokhan
- Atkins William
- Atkinson Kate
- Attwood Joseph
- Auerkari Aino
- Augestad Knut Magne
- Augustin Goran
- Aujayeb Avinash
- Avella Pasquale
- Awad Ahmed K.
- Awad Hadeel
- Awad Rabih
- Awad Selmy
- Ayad Kusay
- Ayana Birhanu
- Aydin Yener
- Ayeni Funbi
- Aytac Erman
- Azab Ahmed
- Azami Rizwan
- Azize Diallo Abdoul
- Azzam Ahmed Y.
- Azzis Olivier
- Baba Yabasin Iddrisu
- Babis George
- Bacalbasa Nicolae
- Badiani Sarit
- Badran Saif
- Baduell Albert
- Baeesa Saleh
- Baertschiger Reto
- Bafaquh Mohammed
- Bahassan Omar Mohammed
- Bahrami-Hessari Michael
- Baia Marco
- Baidoo Ebikela Ivie
- Bailey Karen
- Baili Efstratia
- Bains Lovenish
- Baiocchi Gian Luca
- Baiocchi Glauco
- Baiyewu Lateef Ayodele
- Bajaj Ankur
- Bajunaid Khalid
- Balagobi Balasingam
- Balasubramanian Ishwarya
- Balduzzi Alberto
- Baldwin Alexander
- Balla Andrea
- Balogh Zsolt J.
- Balogun James A.
- Balogun Simon
- Baloyiannis Ioannis
- Ban Vin Shen
- Bandyopadhyay Samik Kumar
- Bandyopadhyay Soham
- Banerjee Sumit
- Banipal Gurpreet Singh
- Banky Balazs
- Bannone Elisa
- Bansal Sujesh
- Barberis Andrea
- Barbosa-Breda Joao
- Bareka Metaxia
- BariĆĄiÄ Tatjana
- Barlas Aziz Mutlu
- Barlow Ciaran
- Barmayehvar Behrad
- Baroffio Paolo
- Barone Mirko
- Barra Fabio
- Barranquero Alberto G.
- Barugola Giuliano
- Basendowah Mohammed
- Bashir Mahmod
- Basnayake Oshan
- Bass Gary Alan
- Basu Somprakas
- Bateman Antony
- Bateman Kellie
- Batista Sylvia
- Batstone Martin
- Bauer Marlies
- Bauset Juan Carlos CatalĂĄ
- Bawa Ashvind
- Bawa Sayesha
- Bayhan HĂŒseyin
- Bayo Heura Llaquet
- Bazzi Nagham
- Beamish Andrew
- Beasley Nigel
- Beatty Jasmine Winter
- Becerra Angel
- Bedada Alemayehu Ginbo
- Bedzhanyan Arkady
- Begum Farzana
- Beisenov Bekzat
- Bellio Gabriele
- Bello Usman Mohammed
- Bellés Ana Ciscar
- Belzile Etienne
- Benamar Safia
- Bence Matthew
- Benshetrit Guy
- Bensoltane Khadidja
- Bergkvist David JuliĂ
- Beristain-Hernandez Jose-Luis
- Bernante Paolo
- Bernardi Daniele
- Beron Reinaldo Isaacs
- Berselli Bruno
- Berselli Mattia
- Bertelli Giacomo
- Bertoglio Pietro
- Bertolaccini Luca
- Beswick Daniel
- Bette Birgit
- Bezirci Rifat
- Bhangu Aneel
- Bharathan Rasiah
- Bhat Vivek
- Bhatti Khalid
- Bianchi Valentina
- Bianco Francesco
- Bianco Giuseppe
- Bijou Walid
- Bilfaqirah Majed
- Biloslavo Alan
- Bin Alhassan Baba Alhaji
- Binnawara Muhannud
- Bissacco Daniele
- BÄ°ĆGÄ°N TAYFUN
- Blair James
- Blanco Jose
- Blencowe Natalie
- Bloemers Frank
- Board Timothy
- Bobak Peter
- Boccalatte Luis
- Boedo Maria Jesus Maroño
- Bohmer Rob
- Boira Mar Achalandabaso
- Boisson Matthieu
- Boligo Sofia
- Bolton William
- Bombardini Cristina
- Bonavina Luigi
- Bonci Eduard-Alexandru
- Bondurri Andrea
- Bonilla Antonio Ramos
- Bonsaana Gilbert Batieka
- Booth L.
- Borg Elaine
- Borges Miguel FrĂłis
- Borges Nuno
- Bork Ulrich
- Borselle Dominika
- Bortul Marina
- Botelho Pedro
- Bottari Andrea
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- Bouliaris Konstantinos
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- Bowen Joel
- Bozbiyik Osman
- Bracale Umberto
- Brachini Gioia
- Bramis Konstantinos
- Branagan Graham
- Branzan Daniela
- Brasset Camille
- Bratus Dejan
- Bravo Ana Maria Minaya
- Bravo Sybil Lizanne
- Bright Tim
- Brisinda Giuseppe
- Brodkin Edgar
- Broglia Alessandro
- Brolese Alberto
- Browning Rebecca
- Bruzzaniti Placido
- BrzeszczyĆski Filip
- Bsisu Isam
- Bua Emmanuel
- Budd Gabrielle
- Bukhari Syed Imran
- Bulian Dirk Rolf
- Bumbasirevic Uros
- Bumber Boris
- Burgos-Blasco Barbara
- Burlov Nikita
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- BĂ mbina Fabrizio
- Börner Nikolaus
- Böttcher Arne
- Cabeza Leticia
- Cabrera Marino
- Cais Simon
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- Calabretto Francesca
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- Callcut Rachael
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- Campo Flaminia
- Campuzano Nicolas
- Cano-Trigueros Emiliano
- Capella Stefano
- Capitan-Morales Luis-Cristobal
- Capobianco Mattia
- Capolupo Gabriella Teresa
- Capozzi Enrico
- Cappuccio Micaela
- Capuano Marianna
- Carannante Filippo
- Carbone Fabio
- Carbone Ludovico
- Caretto Marta
- Caricato Chiara
- Caricato Marco
- Carpenter Holly
- Carreras-Castañer Anna
- Carretero Manuel Moriche
- Caruana Edward J.
- Carvello Michele
- Casagranda Biagio
- Cassese Gianluca
- Cassinotti Elisa
- Castagnini Francesco
- Castaldi Antonio
- Castaño Mario
- Castaño-Leon Ana M.
- Castillo Dayan Fanery Campino
- Castillo Monica Noguez
- Castro Ernes John
- Catarzi Lisa
- Caubet Maria Mercedes
- Caziuc Alexandra
- Ceelen Wim
- Celik Burak
- Cerovac Anis
- Cerovac Elmedina
- Chamakhi Amine
- Champagne Pierre-Olivier
- Chan Albert
- Chan Linda
- Chan Matthew
- Chaplin Helen
- Charalabopoulos Alexandros
- Chatzikomnitsa Paraskevi
- Chaudhary Muhammad Amjad
- Chaudhary Muhammad Hamid
- Chauhan Govind Singh
- Chauhan Munish
- Chean Chung Shen
- Cheetham Mark
- Cherbanyk Floryn
- Cheung Lok Ka
- Chevallay Mickael
- Chiaradia Angela
- Chin Synn Lynn
- Ching Laine Valerie Kongsun
- Chirca Alexandru
- Chisthi Meer
- Choong Peter
- Chopra Sharat
- Choron Rachel
- Choudhry Asad
- Chouliaras Christos
- Chowdhury Mahbub
- Chowdhury Sharfuddin
- Chowdhury Subhadip Pal
- Christidis Panagiotis
- Christodoulidis Gregory
- Christodoulou Prokopis
- Chrysovitsiotis Georgios
- Chu Michael Jen Jie
- Chukwu Isaac
- Chwat Carina
- Cianci Pasquale
- Cicerchia Pierfranco Maria
- Ciftci Ahmet Burak
- Cil Aylin Pelin
- Cillara Nicola
- Cina Caterina
- Ciniero Valeria
- Cioffi Stefano Piero Bernardo
- Cipolla Calogero
- Cisneros Juan Roberto Torres
- Ciubotaru Cezar
- Claireaux Henry
- Clancy Cillian
- Claret Guillem
- Clegg Rachael
- Clementi Marco
- Clerc Daniel
- Clune Edward
- Coates Amy
- Cobianchi Lorenzo
- Coccolini Federico
- Cockbain Andrew J.
- Cohnert Tina
- Coimbra Fernandez
- Cokan Andrej
- Colak Elif
- Colasanti Roberto
- Cole Simon
- Collins Michelle L.
- Colombari Renan Carlo
- Colombo Francesco
- Colucci Nicola
- ColĂĄs-Ruiz Enrique
- Consani Heitor
- Conso Christel
- Consorti Giuseppe
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- Coppola Federico
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- Costea Radu
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- Coughlin Patrick
- Cox Daniel
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- Crichton Robert
- Critchley Rebecca
- Croghan Stefanie M.
- Cross George W. V.
- Cruz Ricardo Pedrini
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- Cullinane Carolyn
- Cullis Paul
- Cunha Miguel F.
- Cunningham Brian
- CurrĂČ Giuseppe
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- Cutmore Carina
- Czako Ladislav
- CĂĄceres Freud
- D'Acapito Fabrizio
- D'Addino José Luis
- D'Amico Alessia
- D'Amore Anna
- D'Andrea Giancarlo
- D'Archi Sabatino
- D'Oria Mario
- D'Sa Prashanth
- Daddi Niccolo'
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- Dajani Khaled
- Dajti Irida
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- Das Sunit
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- Davies Mark
- Davies Richard Justin
- Davis Amelia
- Dawson Amanda Caroline
- Dawson Jonathon
- Dbouk Samer
- De AlarcĂłn Jaime RodrĂguez
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- De La Infiesta GarcĂa Carlos
- De La Medina Antonio Ramos
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- De Oliveira Gabriel Paiva
- De Pastena Matteo
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- De Zuanni Marco
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- Degarege Dawit
- Degener Stephan
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- Demetrashvili Zaza
- Demetriades Andreas K
- Demetriou Charis
- Demir Sebahattin
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- Dölker Theresa
- Eardley Nicola
- Ebrahim Abdulla
- Echieh Chidiebere Peter
- Edwards John
- Efetov Sergey
- Efremov Sergey
- Egan Richard
- Eiras Miguel Angel Freiria
- Eisa Elamin
- Ekor Oluwayemisi
- Ekwen Gerald
- Ekwunife Okechukwu Hyginus
- El Assaad Hadi
- El Boghdady Michael
- El Tayeb Essam Eldien Abuobaida Banaga Hag
- El-Boghdadly Kariem
- El-Hussuna Alaa
- El-Kassas Mohamed
- Elagili Ahmed
- Elahi Zain
- Elbadawy Merihan A.
- Elbahnasawy Mohamed
- Elbe Peter
- Elboraei Rahma
- Eldabaa Mohamed
- Elebute Olumide
- Elfeki Hossam
- Elfiky Mahmoud
- Elgazar Amr
- Elghadban Hosam
- Elhadi Muhammed
- Elhassan Wael Atif Fadl
- Elkazaz Ahmed
- Ellafi Amera Ali Dakheel
- Elliot R.
- Elnour Moheyaldien Ahmed Elamin
- Elsadek Menan
- Elsahli Saifaleslam
- Elsalhawy Shady
- Elsayem Karam
- Elshahawy Mahmoud Abdelaziz Mohamed
- Elsherbiny Ahmed
- Eltayeb Momin
- Elzwai Suha
- Emara Moataz Maher
- Embarek Hussein
- Emile Sameh
- Emmanuel Muhawenimana
- Enciu Octavian
- English Camilla
- Enodien Bassey
- Enwerem Kenneth
- Erel Serap
- Ergenç Merve
- Ergenç Muhammer
- Erginöz Ergin
- Eroglu Atilla
- Escobar Pedro
- Escobedo Francisco Jose Barbosa
- Escrevente Ricardo
- Eskinazi Diego
- Esposito Sofia
- Eugene Muneza
- Ezanno Anne-Cecile
- Ezeanochie Michael
- Ezeme Constantine
- Ezenwa Ekene
- Ezomike Uchechukwu
- Fadalla Tarig
- Fadel Zahir T
- Fahim Margo Medhat Fouad
- Fahmy Ali
- Faiz Javaria
- Fajardo Rafael Torres
- Fakhradiyev Ildar
- Fallah Jean-Michel
- Familiari Pietro
- Fang Clarissa Ern Hui
- Faponle Folayemi
- Farhan-Alanie Muhamed
- Farid Shahzaib
- Farooq Muhammad
- Fatima Mishal
- Fayad Elsayed A.
- Federer Simon
- Federico Nicoletta Sveva Pipitone
- Feeney Kaylem
- Fehervari Matyas
- Fekaj Enver
- Fernandez Laura Gomez
- FernĂĄndez Julio Domenech
- Ferracci Federica
- Ferrara Francesco
- Ferrari Davide
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- Ingabire J. C. Allen
- Ingallinella Sara
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- Katechia Devvrat
- Katorkin Sergey
- Katsaros Ioannis
- Katsiaras Lykoyrgos
- Katsura Morihiro
- Kauppila Joonas H
- Kaur Amanjot
- Kausar Nabila
- Kavalakat Alfie
- Kavanagh Marcel MarjanoviÄ
- Kazan Ozgur
- Kealey Joshua
- Kebede Ephrem
- Kedwany Ahmed
- Kelly Michael
- Ken-Amoah Sebastian
- Kenington Cleo
- Kennerton A.S.
- Kent Alistair J
- Keramati Mohammad Reza
- Kethy Fagnon
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- Klatte Tobias
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- Koneru Anish
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- Kroon Hidde M.
- Kruse Philippe
- Kryzauskas Marius
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- Kusuma Venkata Ramana Murthy
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- Köglberger Paul
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- Königsrainer Ingmar
- Labib Peter
- Laborde Mario Mella
- Lacorbiniere Karisha
- Ladipo-Ajayi Oluwaseun
- Laeke Tsegazeab
- LaganĂ Antonio Simone
- Laird Alexander
- Lakpriya Sathya
- Lam Yick Ho
- Landaluce-Olavarria Aitor
- Lantone Giuliano
- Lapolla Pierfrancesco
- Laporte Gustavo
- Larabi Khadidja
- Lasithiotakis Konstantinos
- Lasrado Savita
- Latif Ejaz
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- Lawal Taiwo Akeem
- Lazarides Alexander
- Lazarou Lazaros
- Lebe Moritz
- Lechuga Daniel Garay
- Ledda Virginia
- Lederhuber Hans
- Lee Susan
- Lenzi Riccardo
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- Leonard Laura
- Leventoǧlu Sezai
- Lever Gillian
- Li Elizabeth
- Li Zoe
- Liakakos Theodore
- Liang Rhea
- Licari Leo
- Lichman Leonid
- Lieske Bettina
- Lightfoot Nicholas
- Lillywhite Robert
- Lim Yizhe
- Lima Leonardo Santos
- Lin Shuxun
- Lindegger Daniel
- Linero Inmaculada BenĂtez
- Ling Samuel
- Lisi Giorgio
- Litta Francesco
- Litvin Andrey
- Lizzi Vincenzo
- Locatello Luca Giovanni
- Lohmann Tibor Karl
- Lohse Helmut Alfredo Segovia
- Lohsiriwat Varut
- Lombardi Pietro Maria
- Lombardi Raffaele
- Lopez Paloma Rodriguez
- Losada Manuel
- Lostoridis Eftychios
- Lotz Christopher
- Loubani Mahmoud
- Loureiro Luis
- Lowery Aoife
- Luc Jessica
- Lucas Miriam Abellan
- Lucchini Stefano
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- Lumenta David Benjamin
- Lun Elizabeth Weng Yan
- Lunca Sorinel
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- Luzzi Andrea-Pierre
- Lyra Humberto Fenner
- Mabood Waleed
- MacChiavello Roberto
- MacHain V Gustavo Miguel
- MacHairas Nikolaos
- MacĂas Rosa Montero
- Madhuri Thumuluru Kavitha
- Madhvani Kiran
- Maestri Marco
- Maffioli Anna
- Maffuz-Aziz Antonio
- MagalhĂŁes Carlos
- Maggiore Giandomenico
- Magnone Stefano
- Magouliotis Dimitrios
- Maguire Patrick J.
- MaheÄiÄ Tina TomiÄ
- Mahmood Fahad
- Mahmoud Abdelrahman
- Mahmud Ayesha
- Mains Edward
- Maiola Vincenza
- Majbar Anass Mohammed
- Majd Hooman Soleymani
- Majid Haroon Javaid
- Makanjuola Ayomide
- Mako Aleksandro
- Makwe Christian Chigozie
- Malagnino Alessia
- Malek Bouhani
- Malik Aamer
- Malik Awais Amjad
- Malik Muhammad Isfandyar Khan
- Malik Sobia
- Mallick Rebecca
- Mallmann Christoph
- Mallmann Michael R.
- Mambrilla Sara
- Manangi Mallikarjuna
- Manesh Hassan Fatemi
- Manfredelli Simone
- Mangi Ali
- Maniaci Antonino
- Manickavasagam Jaiganesh
- Manigrasso Michele
- Manjula S.
- Mannan Syed
- Mantziari Styliani
- MaquilĂłn Alejandra Jara
- Marafante Chiara
- Marano Luigi
- Marei Mahmoud
- Mariani NicolĂČ Maria
- Marino Fabio
- Marom Gad
- Marra Angelo Alessandro
- Marriott Paul
- Marson Ben
- Martellucci Jacopo
- Martin Benjamin
- Martin Janet
- Martinelli Fabio
- Martinez-Leo Bruno
- Martinez-Mier Gustavo
- Martinez-Perez Carolina
- Martinez-Said Hector
- Martins Ana
- Martins Claudia Pinto
- Martins Paulo N.
- MartĂnez Daniel FernĂĄndez
- MartĂnez Eunate Ganuza
- MartĂnez VerĂłnica MartĂn
- MartĂnez-SĂĄnchez Marta Isabel
- Masciello Fabrizio
- Masri Ruqaya
- Massaguer Clara
- Massoud John
- Mata Javier
- Mateo-Sierra Olga
- Materazzo Marco
- Mathew Ryan
- Matos Leandro
- Matos Philomena Alice Wawer
- Matthews Emily
- Mauriello Claudio
- Maurus Christine
- Mayer Horacio F.
- Mayo-Yåñez Miguel
- Mazzarella Gennaro
- Mbodi Langanani
- Mbwele Bernard
- McAleer Stephen
- McCarthy Claire
- McGrath John
- McKay Joseph
- McLean Aaron Lawson
- McLeish Bethan
- McPherson Duncan
- Meara John G.
- Meead Adullah
- Mehraj Asif
- Meilak Joseph
- Meleiro Hugo
- Melero Alba Vazquez
- Melo Miguel Rocha
- MemiĆoǧlu Ecem
- Memos Nikolaos
- Mendes Tome
- Mendiola Gian
- Mendoza-Moreno Fernando
- Meneghini Simona
- Mengesha Mengistu G.
- Menna Maria Paola
- Menon Arun
- Meola Antonio
- Merayo Marta
- Mercante Giuseppe
- Merghani Safa
- Meriç Serhat
- Mesina Cristian
- Mesli Smain Nabil
- Messner Franka
- Mewafy Mahmoud
- Meyer Jeremy
- Micha Georgia
- Michael Afieharo
- Michael Antony Louis Rex
- Migliore Marcello
- Migliorelli Federico
- Mihanovic Jakov
- Mikalauskas Saulius
- Milana Flavio
- Milanesi Damiano
- Milella Oronzo
- Miller Clemens
- Millward Christopher Paul
- Mingoli Andrea
- Mirica Radu Mihail
- Mishra Brijesh
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- Miskovic Josip
- Mitra Jayanta Kumar
- Mittal Abhishek
- Mittal Rohin
- Mittal Rohin
- Mittal Samarth
- Mittal Yash
- Mittermair Christof
- Mitul Ashrarur Rahman
- Moda Nupur
- Modabber Ali
- Modolo Maria Marta
- Mohamed Ahmed Mohamed Ibrahim
- Mohamed Guleed
- Mohamed Mazin
- Mohamedahmed Ali Yasen Y.
- Mohammed Alhassan Datti
- Mohammed Alsnosy Abdullah Khalefa
- Mohammed-Durosinlorun Amina
- Mohan Helen
- Mohan Rajashekar
- Mok Chi Wei
- Molina-Corbacho Matilde
- Moloo Husein
- Mondi Isabella
- Mongelli Francesco
- Montuori Mauro
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- Moreau Joshua
- Morelli Luca
- Moreno Amabelle
- Moreno Carlos Guijarro
- Morezzi Daniele
- Morgan Eghosa
- Moris Dimitrios
- Moro Alessandro
- Moro Ana MarĂa Gimeno
- Moro-Valdezate David
- Morris Richard
- Mostafa Badr
- Motas Natalia
- Mouawad Nicolas
- Mourmouris Panagiotis
- Mousafeiris Vasileios
- Mousli Alaa
- Moynihan Alice
- Muduly Dillip
- Muhaisen Mo'Nes
- Muhammad Abubakar Bala
- Muhammad Sagir
- Muhammad Saminu
- Mukherjee Dattatreya
- Mulita Francesk
- Munthali James
- Musadaq Muhammad
- Mushtaq Hassan
- Musina Ana-Maria
- Mustafa Hamid
- Muthu Sathish
- Mutlu Ăzgecan Piril Zanbak
- Mutter Didier
- Mvukiyehe Jean Paul
- Mwenda Aruyaru Stanley
- Myrelid Par
- Myriokefalitaki Eva
- MĂ©ndez Patricia Serrano
- Nabil Fatma
- Nachelleh Emmanuel Aadereyir
- Nacion Aeris Jane D.
- Nadi Khaldoun
- Naegele Felix
- Naga Hani
- Nagappa Mahesh
- Naggs Taryn
- Nah Shireen Anne
- Nahm Christopher
- Naimzada Mukhammad David
- Nakano Luis
- Nanjiani Deedar
- Nankivell Paul
- Naranjo Eddy P. Lincango
- Narayanan Vairavan
- Nardo Bruno
- Narvaez-Rojas Alexis Rafael
- Nassar Mahmoud A.
- Nasser Sara
- Nastos Constantinos
- Natale Joseph
- Nataraja Ramesh
- Nathan Arjun
- Naumann David
- Navarrete-PeĂłn Alberto
- Navarro-Barrios Alvaro
- Nazer Ahmed
- Nazimi Abd Jabar
- Ncogoza Isaie
- Neal-Smith Gregory
- Neary Colm
- Negoi Ionut
- Negussie Abraham
- Nemeth Marcus
- Nenna Antonio
- Nepogodiev Dmitri
- Nestor Claire
- Nevins Edward J.
- Newman Samuel
- Ngaserin Sabrina
- Nicholson Gary
- Niewiera Marc
- Nigh Joe
- Nikolouzakis Taxiarchis
- Nikolovska Bisera
- Nikova Alexandrina
- Nissi Evelyn R.
- Nitschke Christine
- Njokanma Iloba
- Noel Colin
- Nolte Peter
- Noureldin Yasser
- Novello Simone
- Novysedlåk René
- Ntalouka Maria P.
- Ntirenganya Faustin
- Nugur Ashwani
- Nuhu Ahmed Mohammed
- Nunes Rafael Leite
- Nuñez Jorge
- Nwafor Ikechuwu
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- O'Connell Robert Michael
- O'Connor Alexander
- O'Dwyer Marliza
- O'Riordan James
- Odai Emeka Danielson
- Odicino Franco
- Ofori Emmanuel Owusu
- Ogu Rosemary
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- Oh Ke En
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- Ojo Owolabi
- Okere Oghenekevwe
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- Okpani Charles
- Oktseloglou Vlasios
- Okunade Kehinde
- Oladimeji Abraham
- Olaogun Julius
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- Olori Samson
- Olson Kristofor A.
- Oludara Mobolaji
- Omar David
- Omar Islam
- Omer Mohammed Eltahier Abdalla
- Ong Chon Sum
- Onyeagwara Ngozi
- Onyemaechi Ndubuisi
- Ooi Rucira
- Orecchia Luca
- Ornaghi Sara
- Orsoo Soyombo
- Ortega Eduardo Nieto
- Osborn Tamara
- Oshodi Yusuf
- Osman Hany
- Osman Osama Saeed
- Osterhoff Georg
- Othman Ahmad Faidzal
- Othman Amani Alsayd Abdulsalam
- Othman Rema
- Otify Esraa
- Otokwala Job
- Oung Thida
- Oyinloye Oluwaseun
- Ozair Ahmad
- Ozkan Omer Faruk
- Ozmen Berk Baris
- Paal Peter
- Pachajoa Diana Alejandra Pantoja
- Pacheco Glenda Marina Falcon
- Pacilio Carlo Alberto
- Pacilli Maurizio
- Padmore Greg
- Page Richard
- Paiella Salvatore
- Palacios Nelson Morales
- Palepa Anna
- Palini Gian Marco
- Palmisano Silvia
- Palomba Giuseppe
- Panahi Pedram
- Panda Bijnya
- Pandey Diwakar
- Panduro-Correa Vicky
- Pang Tony
- Paniagua Ladislao Cayetano
- Panieri Eugenio
- Pantuso Gianni
- Papa Adrian
- Papa Mario Virgilio
- Papadoliopoulou Maria
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- Papalia Rocco
- Papatheodorou Panayiotis
- Papavasiliou Kyriakos
- Paranjape Charudutt
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- Paraskevopoulos Konstantinos
- Parini Sara
- Park James
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- Parker Robert
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- Parwaiz Hammad
- Pascale Angelo
- Pascale Giovanni
- Pascale Marco Maria
- Pascarella Giuseppe
- Paspala Anna
- Pata Francesco
- Patel Panna
- Patel Tapan
- Patkar Shraddha
- Patrone Renato
- Pattacini Gianmaria Casoni
- Payne Rachel
- Pazmiño Patricio Andrés Freile
- Peckham-Cooper Adam
- Pecoraro Felice
- Pedini Domiziana
- Pejkova Sofija
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- Pellini Raul
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- Peltrini Roberto
- Peral Ana
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- Peristeri Dimitra
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- Peros Georgios
- Perra Teresa
- Perrone Gennaro
- Perrotta Gerardo
- Persad Amit
- Pertea Mihaela
- Pessaux Patrick
- Petagna Lorenzo
- Petersen Maria Laura
- Petrone Patrizio
- Petrucciani NiccolĂČ
- Petruzzi Gerardo
- Pettigrove K.L.
- Phillips Jonathan
- Picardi Biagio
- Picchetto Andrea
- Picciariello Arcangelo
- Picciochi Maria
- Pickett Gwynedd
- Picotti Veronica
- Pieteris Linas
- Pigeolet Manon
- Pilkington Isobel
- Pillerstorff Robert
- Pineda Ana MejĂa
- Pinkney Thomas
- Pinney L.
- Pinotti Enrico
- Pinto Romina
- Piozzi Guglielmo NiccolĂČ
- Pira Biagia La
- Pires Robinson Esteves
- Pirola Giacomo Maria
- Pirozzi Brunella Maria
- Pirrello Roberto
- Pirzada Muhammad Taqi
- Pissaridou Maria Katerina
- Pitcher Meron
- Pitoni Sara
- Pizzini Paolo
- Pk Parvathy
- Plata-Bello Julio
- Pockney Peter
- Podda Mauro
- Poillucci Gaetano
- Pollok Joerg Matthias
- Pontecorvi Emanuele
- Porcu Alberto
- Potamianos Spyridon
- Potten Stephanie
- Pournaras Dimitri
- Power Nicholas
- Prada Carlos
- Pradhan Akhilesh
- Pramesh C.S.
- Prats Milagros Carrasco
- Prieto Mikel
- PrijoviÄ NebojĆĄa
- Prodromidou Anastasia
- Proud David
- Prucher Gian Marco
- Prusty Lydia
- Pu Jingya Jane
- Pucher Philip
- Punjabi Prakash P
- Puri Ajay
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- Yusefi Hossein
- Zabaleta Jon
- Zabkiewicz Catheriner
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- Zahid Zahra
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- Zapata Carlos Shiraishi
- Zarif Pierre
- ZarĂĄnd Attila
- Zehnder Philipp
- Zenger Serkan
- Zenha HorĂĄcio
- Zhu Michael Z. L.
- Ziemann Sebastian
- Zimak Danijela Mrazovac
- Zimak Zoran
- Zivkovic Dragana
- Zizzo Maurizio
- Zucker Benjamin
- Zwain Yasir
- Zyskowski Michael
- Ăvila Clara Castro
- ĂlgĂ„ Andreas
- Ăakici Mehmet Ăaǧlar
- Ăelik Enes
- Ăelik Meryem Nur
- Ăzçay Necdet
- Ćevik HĂŒsnĂŒ
- Ć antak Goran
- Ć imko KristiĂĄn
- ĆœateckĂœ Jan
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2023
- Field of study
Abstract
Background
Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres.
Methods
This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and lowâmiddle-income countries.
Results
In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of âsingle-useâ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for lowâmiddle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia.
Conclusion
This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both highâ and lowâmiddleâincome countries
Cribado oportunista cancro colo uterino Âżseguimos os protocolos no CS?
- Author
- Publication venue
- Publication date
- 01/01/2011
- Field of study
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- Arango  Maria Clara Mendoza
- Arbane  Gill
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- Bajaj  Ankur
- Balanta-Melo  Juliån
- Balasubramanya  Supriya
- Bali  Oussama
- Baliarsing  Lipika
- Ball  Alasdair
- Ballouhey  Quentin
- Ban  Vin Shen
- Bankhead-Kendall  Brittany
- Bankhead-Kendall  Brittany
- Barillas  Sabrina
- Barker  John
- Barros  Aldo Vieira
- Basnayake  Oshan
- Bastet  Joaquin
- Basu  Somprakas
- Bateman  Antony
- Bath  Michael
- Batista  Sylvia
- Bauset  Juan Carlos Catalå
- Bayo  Heura Llaquet
- BaĂa  Catarina
- Behzadi  Abdollah
- Bekele  Kebebe
- Bele  Uros
- Bele  Uros
- Bellver  Pedro Palazon
- Ben Amer  Anass
- Benallel  Nassim
- Benson  Ruth
- Berber  Norberto
- Bergeat  Damien
- Bergkvist  David JuliĂ
- Bernal-Sprekelsen  Juan Carlos
- Berndtson  Allison
- Bertrand  Marta
- Bescós  Coro
- Bezabih  Yoseph Solomon
- Bhanderi  Shivam
- Bhangu  Aneel
- Bhangu  Aneel
- Bhat  Dhananjaya
- Bhatti  Abu Bakar Hafeez
- Bhende  Vishal
- Bhutiani  Neal
- Bianco  AgustĂn
- Biccard  Bruce
- Blanco-Colino  Ruth
- Blanco-Colino  Ruth
- Blanco-Colino  Ruth
- Blasco  Laura Sånchez
- Boccalatte  Luis
- Boccalatte  Luis
- Boccalatte  Luis
- Boira  Mar Achalandabaso
- Boisson  Matthieu
- Bolatbekova  Raikhan
- Bolger  Jarlath
- Bollano  Enton
- Bonci  Eduard-Alexandru
- Bonci  Eduard-Alexandru
- Borda-Luque  Giuliano
- Boretto  Jorge G.
- Borges  Filipe Castro
- Bork  Ulrich
- Borowski  David W.
- Botero  Marcela Velez
- Bouaoud  Souad
- Bouche  Pierre-Alban
- Bouchenak  Kamel
- Boucher  Sophie
- Boudou  Rocio
- Bouhuwaish  Ahmad
- Brandariz  Rodrigo
- Branquinho  Rita
- Brar  Amanpreet
- Brar  Amanpreet
- Bravo  Ana Maria Minaya
- Bravo  Ana Maria Minaya
- Breen  Kerry
- Brennan  Caitlin
- Brien  Stephen O.
- Bright  Tim
- Brown  Wendy
- Brunaud  Laurent
- Brunner  Stefan M.
- Buarque  Igor Lima
- Bucyibaruta  Georges
- Bukhari  Syed Imran
- Buljubasich  Martin
- Burchakchi  Arturo
- Burgan  Dania
- Busnelli  Virginia Cano
- Buttaro  Martin
- Butyrskii  Aleksandr
- Bwala  Kefas
- Bywater  Edward P.
- C Â Ricci
- Caiado  André
- Caicedo  Lina
- Cal  Fernando Bonilla
- Callcut  Rachael
- Calvache  Albaro José Nieto
- Calvache  Jose Andres
- Calvache  Jose Andres
- Calvache  Jose Andres
- Calzaretta  Laura Gisela Alvarez
- Campana  Juan Pablo
- Campos  Heloisa Galvão do Amaral
- Capitaine  Daniel
- Cappeliez  Serge
- Cardoso  Paulo
- Carmichael  Heather
- Carminatti  Tomas
- Carrera  Jacqueline
- Carreras-Castañer  Anna
- Caruana  Edward
- Cereghini  Julian
- Cerovac  Anis
- Cerovac  Anis
- Chadi  Sami
- Chakrabortee  Sohini
- Chan  Matthew
- Chandrasinghe  Pramodh
- Chapatwala  Reema
- Charbonneau  Helene
- Charles  Shane
- Chaudhary  Muhammad Hamid
- Chaudhry  Daoud
- Chaudhry  Daoud
- Chaudhry  Navneet Kumar
- Chauhan  Govind Singh
- Chebaro  Alexandre
- Chew  Min Hoe
- Chin  Theresa
- Chinyowa  Simbarashe
- Chiuyari  Jose Rios
- Choong  Peter
- Chowdappa  Raghunandan Gorantlu
- Chowdhury  Sharfuddin
- Christensen  Peter
- Chuan  Alwin
- Chwat  Carina
- Chwat  Carina
- Clancy  Cillian
- Coimbra  Felipe José Fernandez
- Coleman  Julia
- Colmenares  Yahaira Tatiana Carpio
- Colås-Ruiz  Enrique
- Connelly  Tara
- Connor  Clare O.
- Coonar  Aman
- Corbett  Harriet
- Corella  Fernando
- Corripio-Sanchez  Ramon
- Costa  Luciana Cidade
- Costas-Chavarri  Ainhoa
- Costea  Radu
- Cotta  EstefanĂa
- Cox  Daniel
- Cox  Daniel
- Creavin  Ben
- Croattini  Roberto Sebastiån
- Croghan  Stefanie M.
- Crétolle  Célia
- Cukier  Moises
- Cukier  Moises
- Cullinane  Carolyn
- Cunha  Miguel F.
- Cunha  Miguel F.
- Dajti  Irida
- Dajti  Irida
- Dajti  Irida
- Daoud  Hassan
- Das  Rishi
- Davies-Jones  Gareth
- Davis  Niall
- Dawson  Amanda Caroline
- Dawson  Amanda Caroline
- Dawson  Brett E.
- Dbeis  Rachel
- De Andrés-Asenjo  Beatriz
- De Cortazar  Unai Garcia
- de Dieu  Haragirimana Jean
- de LeĂłn  Laura RomĂĄn GarcĂa
- De Simone  Belinda
- Dean  Benjamin
- Degefa  Eyueal
- Del Pilar Paucar Urbina  Arazzelly
- Delibegovic  Samir
- Delisau-Puig  Olga
- Dell  Angela
- Demetrashvili  Zaza
- Demetrashvili  Zaza
- Demetriades  Andreas K.
- Derilo  Habtamu
- Desai  Anant
- Deus  Ana Clåudia
- Dharap  Satish
- Dhondt  Bert
- Dhufera  Hailu
- Di Martino  Marcello
- Di Saverio  Salomone
- Di Vincenzo  Marcela
- Diaz-Couselo  Fernando
- Diehl  Thomas
- Dimofte  Mihail-Gabriel
- DiNome  Maggie
- Djahida  Bahraoui
- Doerner  Johannes
- Domenech  Julio
- Donlon  Noel
- Drake  Frederick
- Drake  Thomas
- Drasovean  Radu
- Duarte  Amalia Barrios
- Duarte  Carolina Lugo
- Dube  Surya Kumar
- Duchalais  Emilie
- Dudi-Venkata  Nagendra
- Duran  Irani
- Duric  Natalie
- Duro  Agustin
- Dwaga  Sumayya Essayah
- Dziakova  Jana
- Déserts  Marc Danguy des
- DĂaz-Feijoo  Berta
- Earley  Helen
- Eberbach  Helge
- Edwards  John
- Edwards  John
- Efetov  Sergey
- Efetov  Sergey
- Egoroff  Natasha
- Eiras  Miguel Angel Freiria
- Ekenze  Sebastian
- El Helw  Amin
- El Kafsi  JihÚne
- El-Boghdadly  Kariem
- El-Boghdadly  Kariem
- El-Hussuna  Alaa
- Elhadi  Muhammed
- Elhadi  Muhammed
- Elhajdawe  Fras
- Elliott  Brodie
- Ellojli  Ibrahim
- Elwahab  Sami Abd
- Emerson  Hannah
- Emile  Sameh
- Emile  Sameh
- Enjuto  Diego
- Escartin  Jorge
- Escudero  DamiĂĄn GarcĂa
- Escudero  Mario I.
- Eskander  Antoine
- Espin-Basany  Eloy
- Espino  Pablo Calvo
- Espinosa-Bravo  Martin
- Esquivel  Carlos
- Estruch  Nuria Montferrer
- Etchill  Eric
- Evans  Jonathan
- Evelyn  Nissi
- Ezanno  Anne-Cecile
- Fahadullah  Muhammad
- Fahmy  Mohamed
- Fakhradiyev  Ildar
- Fakhradiyev  Ildar
- Farfus  Anthony
- Farik  Shebani
- Farooq  Umer
- Faulkner  Gemma
- Faustin  Ntirenganya
- Fernandez  Juan Delgado
- Fernandez  Laura Gomez
- Fernandez  Maria Sol
- Fernåndez  Fåtima Sånchez
- Fernåndez-López  Antonio-José
- Ferrer  Antonio Perez
- Ferry  Jenny
- Figari  Marcelo
- Figueroa  Rodrigo
- Figueroa-Casanova  Rafael
- Filipce  Venko
- Filipescu  Daniela
- Fiore  Marco
- Fisseha  Tigist
- Flamey  Nicolas
- Fleming  Christina
- Flexman  Alana
- Fluegen  Georg
- Flumignan  Ronald
- Ford  Samuel
- Forero-Torres  Alexander
- Forneris  Agustin Albani
- Fotopoulou  Christina
- Fowler  Alexander
- Fraidenraij  Uriel
- Fredon  Fabien
- Fuentes  Marta Alcaraz
- Fuentes  Tyare
- Fujimoto  Yuki
- Futaba  Kaori
- Gagnier  Joel
- Gahwagi  Milad
- Gallegos  Diego
- Gallino  Esteban Sebastian
- Gallo  Gaetano
- Ganly  Ian
- Garcia  Manuel
- Garcia-Adamez  Jorge
- GarcĂa  Lucia Diego
- GarcĂa  Pablo MartĂn
- GarcĂa-Mansilla  AgustĂn Maria
- GarcĂa-Montoya  Oscar-JuliĂĄn
- Gaujoux  Sebastien
- Gauna  Guillermo Hernandez
- Gempt  Jens
- Georgiades  Fanourios
- Gerchunoff  José Ignacio
- Ghani  Muhammad Owais Abdul
- Ghazal  Ahmad
- Ghazwani  Salman
- Ghodke  Rahul
- Ghosh  Dhruva
- Ghosh  Dhruva
- Ghosh  Indranil
- Ghozy  Sherief
- Ghunaim  Mohammed
- Gialamas  Eleftherios
- Gialamas  Eleftherios
- Gigena  Cecilia
- Gil-Sala  Daniel
- Ginghina  Octav
- Giorgakis  Emmanouil
- Girard  Edouard
- Girard  Noémie
- Gishanthan  Shanthamoorthy
- Gjata  Arben
- Gjyli  Kostandin
- Glasbey  James C.
- Glasbey  James C.
- Glass  Nina
- Glowka  Tim R.
- Gohar  Muhammad
- Golet  Marta Roldón
- Gomes  Gustavo Mendonça AtaĂde
- Gomez  Jose Tomas Castell
- Gomez-Fernandez  Hugo
- Gomez-Rosado  Juan-Carlos
- Gonzalez  Diana Samantha
- Gonzalez  Marcos
- Gonzalez  Matias Ignacio
- Gonzalez  Santiago Valderrabano
- Gonzålez  Javier Serrano
- Gonzålez-Gimeno  Maria Jose
- Gonzålez-Suårez  Susana
- Goransky  Jeremias
- Gosain  Ankush
- Gourlay  Ralph
- Gousias  Konstantinos
- Gouvas  Nikolaos
- Gouvas  Nikolaos
- Grama  Florin
- Grassano  Bianca
- Greenhalgh  Michael
- Griffiths  Ewen
- Gronchi  Alessandro
- Groot  Gary
- Gross  Jefferson
- Guillen  Jose Ramon Oliver
- Gujjuri  Rohan R.
- Gujjuri  Rohan R.
- Gulla  Aiste
- Gunawansa  Nalaka
- Gupta  Anand
- Gupta  Rahul
- Gurumeta  Alfredo Abad
- Gut  Anna Eleonora
- Gómez  Mercedes Estaire
- Ha  Jeong
- Habumuremyi  Sosthene
- Hadzibegovic  Ana Danic
- Haidar  Hanan
- Haider  Fayza
- Haif  Assia
- Hailu  Samuel
- Hailu  Samuel
- Hakami  Ibrahim
- Hamad  Faten Reyad Bani
- Hamdun  Intisar Hisham Said
- Hameed  Zeeshan
- Hammed  Ali
- Hammond  John
- Haran  Cheyaanthan
- Hardie  John
- Harper  Luke
- Harrison  Ewen M.
- Harrison  Ewen M.
- Hashimoto  Daisuke
- Hassan  Ramy A.
- Hecker  Andreas
- Henein  Christin
- Heredia  Fernando
- Heriot  Alexander
- Hervieux  Erik
- Herzberg  Jonas
- Higuera  Felipe
- Hilmi  Ahmed
- Hirji  Sameer
- Hirschburger  Markus
- Hodgson  Russell
- Holc  Fernando
- Hollington  Paul
- Hollyman  Marianne
- Horch  Raymund E.
- Horisberger  Karoline
- Hossain  Kamral
- Huang  Abel
- Husain  Shatha
- Hutchinson  Peter
- Hyman  Gabriella Yael
- Höhn  Philipp
- Iascano  Fernando Martinez
- Ikele  Hilary
- Imanishimwe  Alphonsine
- Incorvia  Joseph
- Incorvia  Joseph
- Infante  Antonio Rodriguez
- Ingabire  Jc Allen
- Ionescu  Sebastian
- Isaac  Otolia
- Isik  Arda
- Isik  Arda
- Iskander  Othman
- Jain  Kavitha
- Jain  Ritu
- Jamal  Aiman
- Jamal  Mohammad
- James  Harelimana Grace
- Jauregui  Esteban Gabriel
- Javadpour  Mohsen
- Javed  Saad
- Javed  Saad
- Jaworska  Natalia
- Jayarajah  Umesh
- Jayarajah  Umesh
- Jeandel  Clement
- Jenkinson  Michael
- Jimaale  Elmi Ahmed Mohamed
- Jimenez  Raul
- Jimenez  Virginia
- Jiménez  Pablo Mijahil Avilés
- Jiménez  Pablo Mijahil Avilés
- Jin-Young  Jang
- Jira  Moa
- Jisry  Ghassan
- Jlassi  Haithem
- Johnson  David
- Jones  Conor S.
- Jonker  Pascal
- Jouffret  Lionel
- JĂșnior  Samuel Aguiar
- Kaafarani  Haytham
- Kaafarani  Haytham
- Kaafarani  Haytham
- Kabir  Syed Mohammad Umar
- Kabweru  Wilberforce M.
- Kache  Stephen
- Kacimi  Salah Eddine Oussama
- Kaidarova  Dilyara
- Kaiser  Julia Christina
- Kakeeto  Andrew
- Kaman  Lileswar
- Kamarajah  Sivesh K.
- Kamarajah  Sivesh K.
- Kamphues  Carsten
- Kandevani  Naser Yousefzadeh
- Kannan  Ravi
- Karout  Lina
- Karthigeyan  Madhivanan
- Kassir  Radwan
- Kauppila  Joonas H.
- Kauppila  Joonas H.
- Kaups-Fresno  Krista
- Kavalakat  Alfie
- Keatley  James M.
- Kembuan  Gabriele
- Keppler  Alexander M.
- Keppler  Lena
- Kerawala  Asad Ali
- Kerawala  Cyrus
- Kerpaci  Jola
- Khadidja  Kouidri
- Khalifa  Houda
- Khalil  Kareem S.
- Khamees  Almu'atasim
- Khan  Tabassum
- Khatri  Chetan
- Kherani  Safeena
- Khokhar  Muhammad Imran
- Khosravi  Mohammad
- Khosravi  Mohammad Hossein
- Kieser  David
- King  Jasmin
- Kirov  Mikhail
- Kiweewa  Ronald
- Klat  Jaroslav
- Knight  Stephen Richard
- Kochetkov  Viktor
- Koh  Cherry
- Koh  Frederick
- Koh  Frederick
- Kolias  Angelos
- Komen  Niels
- Konate  Ibrahima
- Konrads  Christian
- Kopetskyi  Slava
- Kopjar  Tomislav
- Kornblith  Lucy
- Kowalski  Luiz Paulo
- Koƥir  Jurij Aleƥ
- Koƥir  Jurij Aleƥ
- Kpangon  Cyrille
- Kronberger  Irmgard
- Kronberger  Irmgard Elisabeth
- Kroon  Hidde M.
- Kruijff  Schelto
- Kudsk-Iversen  SÞren
- Kulimbet  Mukhtar
- Kulkarni  Amruta
- Kumar  Aruna
- Kumar  Ashwani
- Kundra  Rakesh
- Kuroda  Naoto
- Kwan  Tsun Yu
- Königsrainer  Alfred
- la Medina  Antonio Ramos-De
- Laban  Simon
- Lakkis  Zaher
- Lakpriya  Sathya
- Lalmi  Ismahene
- LalĂn  Agustina Florencia Castro
- Lami  Mariam
- Landaluce-Olavarria  Aitor
- Larrañaga  Juan
- Latif  Haider
- Lau  Lorena Fuentes Rivera
- Laudani  Veronica
- Laudani  Veronica
- Laura  Saura GarcĂa
- Lavanya Kannaiyan  R.
- Lawal  Taiwo Akeem
- Lawani  Ismaïl
- Lawani  Ismaïl
- Lawday  Samuel
- Le Bian  Alban Zarzavadjian
- Lederhuber  Hans
- Lekuya  Hervé Monka
- Lekuya  Hervé Monka
- Lekuya  Hervé Monka
- Leung  Elaine
- LeventoÄlu  Sezai
- LeventoÄlu  Sezai
- Lewis-Lloyd  Christopher
- Lewis-Lloyd  Christopher
- Li  Elizabeth
- Li  Elizabeth
- Lidder  Surjit
- Lincango-Naranjo  Eddy
- Lincango-Naranjo  Eddy
- Lindert  Judith
- Linz  Valerie Catherine
- Litvin  Andrey
- Litvin  Andrey
- Liveris  Anna
- Liyo  Juan
- Llano  Lionel
- Lo  Terence
- Loaloa  Mohamed Reda
- Lobos  Pablo
- Lohsiriwat  Varut
- Losada  Manuel
- Lott  Natalie
- Lou  Wenhui
- Lowey  Megan
- Lozada  Jorge Centeno
- LoÌffler  Markus W.
- Lucchini  Sergio Martin
- Lucchini  Sergio Martin
- Lueckel  Stephanie
- Lugones  Ignacio
- Lule  Herman
- Lule  Herman
- Lule  Herman
- Luna  Joaquin
- Luzzi  Emilia
- López  Anna Sånchez
- López  Cristina Barrena
- Mabood  Waleed
- Macchiavello  Roberto
- MacKenzie  Shawn
- Madabhavi  Irappa
- Madkhali  Tariq
- Madrid  Constanza
- Mahakalkar  Chandrashekhar
- Maher  Mark
- Maimbo  Mayaba
- Maji  Suvendu
- Majid  Haroon Javaid
- Major  Piotr
- Major  Piotr
- Makdissi  Fabiana
- Makkai-Popa  Silviu Tiberiu
- Maldonado-Marcos  Eloy
- Maleki  Esmaeil Rezghi
- Malik  Muhammad Usman
- Mallén  Victoria Duque
- Manceau  Gilles
- Mann  Harvinder
- Mann  Harvinder
- Mansour  Ahmed
- Maricic  Maximiliano
- Mariño  Lucia Porteiro
- Marquez  Lucila
- Marson  Ella J.
- Martin  Janet
- Martin  Janet
- Martinez  Antonio Alberto
- Martinez  Eneida Diaz
- Martinez  Laura
- Martins  Paulo
- MartĂn  Maria Teresa FernĂĄndez
- MartĂn-LĂĄez  RubĂ©n
- MartĂnez  Daniel FernĂĄndez
- MartĂnez  MarĂa JosĂ©
- MartĂnez  Mireia Riba
- Marçal  André
- Mashbari  Hassan
- Mashhour  Mohamed
- Mashhour  Mohamed
- Mashhour  Mohamed
- Massoud  John George
- Mastroianni  Gustavo
- Mata-Suarez  Santiago Miguel
- Matai  Anil
- Mateo-Sierra  Olga
- Matovu  Paul
- Mayer  Horacio F.
- Mayol  Julio
- Mazingi  Dennis
- Mc Loughlin  Santiago
- McDonnell  Brendan
- McGuinness  Matthew James
- McIntosh  Nick
- McKay  Siobhan
- Mclean  Kenneth A.
- Mclean  Kenneth A.
- McNestry  Catherine
- Meara  John G.
- Meelad  Ayman
- Mege  Diane
- Megersa  Abebe
- Mehraj  Asif
- MejĂa  Dolores
- Melendez  Robinson Mas
- Melero  Alba Vazquez
- Melo  Miguel Rocha
- Mendes  Filipa
- Mendiola  Gian
- Mendoza  Efrain
- Mendoza  Veronica Alonso
- Mengesha  Mengistu G.
- Mengesha  Mengistu G.
- Mengesha  Mengistu Gebreyohanes
- Mentz  Ricardo Esteban
- Meola  Antonio
- Mercado  Pedro
- Mersich  Tamås
- Metallidis  Symeon
- MeÌvo Romaric Tobome  S.
- Michael  Antony Louis Rex
- Migliorelli  Federico
- Mihanovic  Jakov
- Mihanovic  Jakov
- Milan  Peiman Brouki
- Mills  Emily
- Mimica  Ximena
- Mironescu  Aurel
- Mishra  Tushar
- Misra  Sanjeev
- Misrai  Vincent
- Mittal  Rohin
- Mitul  Ashrarur Rahman
- Mlambo  Busisiwe
- Modabber  Ali
- Modolo  Maria Marta
- Modolo  Maria Marta
- Modolo  Maria Marta
- Modolo  Maria Marta
- Mohamed  Awadelkarim
- Mohammed  Alsnosy Abdullah Khalefa
- Mohammed  Diary
- Mohan  Helen
- Mohsen  Mustafa Abo
- Mohyieldin  Omar
- Moir  John
- Molitvin  Yegor
- Mondino  Jose
- Montal  Silvina
- Montenegro  Emileth
- Morales-Puebla  José Manuel
- Morris  Brian
- Morsy  Amr
- Mosley  Frances
- Moss  Jana-Lee
- Mostafa  Badr
- Motas  Natalia
- Moug  Susan
- Moya-Angeler  Joaquin
- Moyano  Pablo
- Mozafari  Masoud
- Mozel  Michelle
- Mozo  Ana Sånchez
- Msherghi  Ahmed
- Mubezi  Isaac
- Muheilan  Muheilan
- Munyaneza  Emmanuel
- Munyika  Akutu
- Muralidharan  Vijayaragavan
- Muriel  MarĂa Emilia
- Mushiwokufa  Willard
- Muthu  Sathish
- Naem  Antoine
- Nagar  Manoj
- Nakagawa  Suely
- Nappi  Francesco
- Naseem  Muhammad Yasir
- Nashidengo  Pueya Rashid
- Nashidengo  Pueya Rashid
- Naunheim  Matthew
- Nayen  Alejandra
- Ncogoza  Isaie
- Ndayishyigikiye  Marcel Didier
- Ndong  Abdourahmane
- Ndong  Abdourahmane
- Negoi  Ionut
- Negoi  Ionut
- Negussie  Abraham
- Nepogodiev  Dmitri
- Nepogodiev  Dmitri
- Nepogodiev  Dmitri
- Nessim  Carolyn
- Neto  Joao Pedreira Duprat
- Newman  Samuel
- Ng-Kamstra  Joshua
- Ngu  James
- Ngulube  Allan
- Niazi  Sami Ullah
- Nicholson  Kristina
- Nidaw  Melkamu
- Nikolaieva  Karine
- Niquen-Jimenez  Milagros
- Nitschke  Christine
- Nkembi  Armande Subayi
- Nogueiro  Jorge
- Noll  Florencia
- Noltes  Milou
- Noltes  Milou
- Norman  Lisa
- Norman  Lisa
- Nouh  Thamer
- Novysedlåk  René
- Novysedlåk  René
- Nowak  Kai
- Ntirenganya  Faustin
- Nunez  Jade
- Nurgozhin  Talgat
- Nuñez  Jorge
- Nuñez  Jorge
- Nwegbu  Chukwuemeka
- NĂșñez  Bernardo
- Odejinmi  Funlayo
- Odetto  Diego
- Ofori  Bernard
- Ojeda  Ximena Paola Vasquez
- Okereke  Chukwuma
- Okonkwo  Ijeoma
- Okunlola  Abiodun
- Olaogun  Julius
- Olaywah  Noor
- Oliva  Agustina Rene
- Oliveira  João
- Olivos  Maricarmen
- Olivos  Maricarmen
- Olori  Samson
- Olson  Kristofor A.
- Omar  Omar M.
- Omari  Rand Y.
- Oosterlinck  Wouter
- Ortiz  Maria Rosa
- Oscco  Regina Amparo Ugarte
- Osinaike  Babatunde
- Ots  Riinu
- Outani  Oumaima
- Outani  Oumaima
- Outani  Oumaima
- Pablo  Carmignani
- Pachajoa  Diana Alejandra Pantoja
- Pacheco  Glenda Marina Falcon
- Pacilli  Maurizio
- Padmore  Greg
- Palacios  Nelson Morales
- Pallardel  Jenner Betalleluz
- Panyko  Arpåd
- Paranjape  Charu
- Parmar  Chetan
- Passadore  Martin
- Pata  Francesco
- Patel  Akshay
- Patel  Rakesh
- Pawar  Pranay
- Peiper  Christian
- Pejkova  Sofija
- Pejkova  Sofija
- Pellino  Gianluca
- Perdomo  Valentina Gutiérrez
- Pereira  Rita Gonçalves
- Perez Rivera  Carlos J.
- Perez Rivera  Carlos J.
- Perez-Chrzanowska  Hanna
- Perinotti  Roberto
- Pfister  Karin
- Phadnis  Ashish
- Picciochi  Maria
- Picciochi  Maria
- Pigeolet  Manon
- Pilar Tormos PeÌrez  M.
- Pius  Riinu
- Plarre  Philipp
- Pockney  Peter
- Pockney  Peter
- Pockney  Peter
- Pockney  Peter
- Poggi  Catalina
- Police  Andrea
- Ponugoti  Nikhil
- Portilla  Ana LucĂa
- Portilla  Fabian Rojas
- Porumb  Vlad
- Powell  Simon
- Prada  Jorge
- Pramesh  C. S.
- Prat-Ortells  Jordi
- Prats  Milagros Carrasco
- Premoli  Eduardo Jorge
- Prieto  Mikel
- Puiggrós  Laura Cårdenas
- Putnis  Soni
- Pykhteev  Vadim
- Pérez  Beatriz Gómez
- Pérez-Bertólez  Sonia
- Qasem  Abdulrahman
- Qassem  Faisal
- Qassem  Mohamed
- Quante  Markus
- Quintana-Villamandos  Begoña
- Qureshi  Ahmad Uzair
- Qureshi  Ahmad Uzair
- R Â Casadei
- Ra'ed  Hazim
- Radenkovic  Dejan
- Raevskaya  Marianna
- Rahbari  Nuh
- Rahy-MartĂn  Aida Cristina
- Rai  Lajpat
- Rajan  Shiv
- Rajanbabu  Anupama
- Ramallo-SolĂs  Irene
- Rammohan  Ashwin
- Ramos  MarĂa Lourdes
- Ramos-Luengo  Adolfo
- Ranganath  N.
- Rasoaherinomenjanahary  Fanjandrainy
- Rassweiler-Seyfried  Marie-Claire
- Rattan  Rishi
- Rattanasirivilai  Pornjittra
- Raut  Monish
- Recinos  Gustavo
- Recinos  Gustavo
- Regalo  Guillermo
- Reim  Daniel
- Reinhard  Tobias
- Reinke  Caroline
- Reisenauer  Janani
- Ren  Dong-Lin
- Rennie  Sarah
- Rennie  Sarah
- Rice  Henry E.
- Rice  Henry E.
- Rida  Ahmed Hossam Eldin Fouad
- Rio  Javier
- Ripollés-Melchor  Javier
- Rissmann  Anke
- Roberts  Keith
- Rodas  Alejandra
- Rodriguez  Juliana
- Rodriguez-Abreu  Julia
- Rodriquez  Jennifer
- RodrĂguez-Tesouro  Ana
- Rogers  Luke
- Rokohl  Alexander Christopher
- Roman  Igor Alberdi San
- Romera  Susana Bella
- Ronellenfitsch  Ulrich
- Rosas  Patricio
- Roslani  April Camilla
- Roslani  April Camilla
- Roslani  April Camilla
- Rossi  Gustavo
- Rossi  Luciano
- Rosso  Andres
- Roth  Andreas
- Rubio-Palau  Josep
- Ruiz  Alitza Gutiérrez
- Ruiz-MarĂn  Miguel
- Russell  Crispin
- RutegÄrd  Martin
- Ruzgar  Nensi Melissa
- Ryan  Ăanna
- Saad  Mahmoud M.
- Saadi  Jose
- Sacdalan  Marie Dione
- Sacdalan  Marie Dione
- Sacras  Maria LuĂs
- Saenz  Dinimo Bolivar
- Safieddine  Najib
- Sagar  Jayesh
- Saier  Tim
- Salazar  Esteban Gonzalez
- Salazar  Ivana Ines Pedraza
- Sale  Danjuma
- Saleh  Ismail Ali
- Salem  Marwa
- Saliev  Timur
- Saliev  Timur
- Sallam  Asser
- Samadov  Elgun
- Samaka  Rehab
- Samison  Luc Hervé
- Sampaio-Alves  Mafalda
- Sancho-Muriel  Jorge
- Sandoval  Danilo Alfonso Arévalo
- Sandoval  Danilo Alfonso Arévalo
- Santos  IrÚne
- Santos  IrÚne
- Santos-Costa  Paulo
- Sanz-Gonzalez  Rosa
- Sarjanoja  Elise
- Sarwar  Muhammad Zeeshan
- Satoi  Sohei
- Satoi  Sohei
- Sauvain  Marc-Olivier
- Sayyed  Raza
- Scalabre  Aurélien
- Schache  Andrew
- Scher  Pablo
- Scherñuk  Jordån
- Schlager  Daniel
- Schmedding  Andrea
- Schnitzbauer  Andreas
- Schoneveld  Martijn
- Seegert  Sara
- Seeliger  Barbara
- Seguin-Givelet  Agathe
- Sekar  Arunkumar
- Serralheiro  Pedro
- Seyi-Olajide  Justina
- Seyi-Olajide  Justina
- Shah  Rakesh
- Shaikh  Shafaque
- Shanthanna  Harsha
- Sharma  Abhishek
- Sharma  Rahul Deo
- Sharma  Shilpa
- Shaw  Catherine
- Shaw  Catherine
- Shaw  Richard
- Shehata  Sameh
- Shehta  Ahmed
- Sherif  Ahmed Elshawadfy
- Shih  Emily
- Shrestha  Ashish Lal
- Shumbash  Kibruyisfaw
- Siamuchembu  Maphios
- Siddique  Haleema
- Sieira-Gil  Ramon
- Sigamoney  Kohila
- Sikakulya  Franck K.
- Silva  Camilo Ortiz
- Silva  Nelson
- Silva-Igua  Liliana
- Simoes  Joana Ff
- Simoes  Joana Ff
- Simoes  Joana Ff
- Sin  MÂȘPilar Canals
- Singh  Harvinder
- Singisetti  Kiran
- Sinnerton  Robert
- Sisay  Silamlak
- Slavchev  Mihail
- Slavchev  Mihail
- Slim  Karem
- Slullitel  Pablo
- Smart  Neil
- Soares  Ana
- Sodhai  Vivek
- Sole  Oriol Martin
- SolĂ©  MisericĂČrdia JordĂ
- Soni  Rajesh
- Sonksen  Julian
- Sooriyabandara  Charitha
- Soria  Vanesa Garcia
- Soto-Darias  Ivån
- Soualili  Zineddine
- Spelsberg  Fritz
- Squiers  John
- Srishankar  Selvaratnam
- St-Germain  Pascal
- Stadler  Josef
- Stang  MarĂa Verona
- Stavridis  Sotir
- Stavrou  Gregor A.
- Steinkamp  Pieter
- Steinkamp  Pieter
- Stephens  Matthew
- Stevens  Sean
- Stewart  Grant D.
- Stewart  Grant D.
- Stijns  Jasper
- Stoleriu  Mircea Gabriel
- Suarez  Marcelo Moreno
- Subbian  Anbukkani
- Suliaman  Taha
- Sultan  Rizwan
- Sultana  Asma
- Sumadi  Adnan
- Sund  Malin
- Surendran  Arthika
- Suroy  Atul
- Szakmany  Tamas
- Sånchez  Alberto Cabañero
- Sånchez  Iran Irani Durån
- SĂĄnchez-CabĂșs  Santiago
- Tabiri  Stephen
- Taboada  MarĂa Victoria
- Tachella  Sofia
- Tadesse  Anteneh
- Talat  Nabila
- Talib  Ahmar Iftikhar
- Talwar  Rishi
- Tamoos  Khalil
- Tampaki  Ekaterini Christina
- Tan  Lorwai
- Tariq  Aiman
- Tariq  Muhammad
- Tarrado  Xavier
- Taylor  Elliott H.
- Teague  Rebecca
- Teasdale  Ella
- Tefera  Teshome
- Tejero-Pintor  Francisco J.
- Tendeng  Jacques
- Teo  Nan Zun
- Teresa GavaldaÌ PelliceÌ Â M.
- Testelin  Sylvie
- Thakar  Sumit
- Thereska  Dariel
- Thereska  Dariel
- Thies  Cristina Ojeda
- Thyavihally  Yuvaraja
- Tirapegui  Sebastian
- Todorovic  Lazar
- Tojal  André
- Tolani  Musliu Adetola
- Toma  Elena Adelina
- Tornini  Alejandra
- Toro  Carlos Andres Marulanda
- Torres  Martha Luz
- Toscano  Marta Jimenez
- Totty  Joshua
- Townend  Philip
- Traeger  Luke
- Traverso  Rogelio
- Tripathi  Manjul
- Trout  Isobel M.
- Trujillo  Lina MarĂa
- Tsegaye  Bereket
- Tsoulfas  Georgios
- Tudela  Kiara
- Turinawe  Gaston
- Turner  Paul
- Turrado-Rodriguez  Victor
- Uffelmann  Constanza
- Ugarte-Sierra  Bakarne
- Usang  Usang
- Vaccaro  Carlos
- Vagni  Roberto
- Vaishnav  Dhaivat
- Valcarcel  Cristina Rey
- Valdez  Pedro
- Valerio  Ana Clara
- Vallam  Karthik Chandra
- Vallve-Bernal  Marc
- van Ramshorst  Gabrielle
- van Ramshorst  Gabrielle
- Vargas  Lara
- Varghese  Chris
- Varghese  Chris
- Varghese  Chris
- Varghese  Chris
- Vartanian  Jose Guilherme
- Vaughan-Shaw  Peter
- Vayoth  Sudheer Othiyil
- Vaysburg  Dennis
- Vaysse  Charlotte
- Velasco  Jorge Caño
- Velasquez  Enrique Jose Ruiz
- Venkatappa  Sunil Kumar
- Venn  Mary L.
- Verhaeghe  Romain
- Verhaeghe  Romain
- Vidal  Rafael Perez
- Vidya  Raghavan
- Vijayakumar Vijayakumar  M.
- Villanueva  Julio
- Vimalakanthan  Thanusan
- Vita  Diana Crego
- Vivancos  Patricia Caja
- Viveiros  Octavio
- Vives  Inmaculada
- Vives  Josep Maria Muñoz
- Vo  Uyen Giao
- von Pusch  Silke
- Vrapi  Enxhi
- Våzquez  Irene Ortega
- Wafi  Omar
- Wagner  Arthur
- Waissbluth  Sofia
- Waqar  Shahzad Hussain
- Watson  David
- Watson  Eleanor
- Watters  David
- Weeraddana  Prabuth Dulanjan
- Wells  Cameron
- Welter  Stefan
- Wettstein  Dåniel
- Wickramasinghe  Dakshitha
- Wickramasinghe  Dakshitha
- Wiegering  Armin
- Wijeysundera  Duminda
- Williams  Emmanuel
- Williams  Omolara
- Williams  Omolara
- Wilson  Michael
- Wolf  Sebastian
- Wolfer  Susanne
- Wong  Enoch
- Wright  Deborah
- Wright  Deborah
- Wright  Naomi
- Wuraola  Funmilola
- Wuraola  Funmilola
- Xaviour  Okedi Francis
- Xu  William
- Yadev  I.
- Yagoub  Ghozlan
- Yaqoob  Eesha
- Yaqoob  Hassan Nawaz
- Yasin  Seid Mohammed
- Yazbek  Guilherme
- Yebes  Alvaro
- Yeung  Justin
- Yip  Sebastian Shu
- Youssef  Mina
- Zabaleta  Jon
- Zahid  Imdad Ahmad
- Zanoni  Gerardo
- Zapardiel  Ignacio
- Zapata  Carlos Shiraishi
- Zarnescu  Narcis Octavian
- Zarour  Ahmad
- Zarour  Ahmad
- Zarour  Ahmad
- Zarratea  Celeste Soledad
- Zegarra  Sergio
- Zequi  Stenio C.
- Zezular  Damaris Idara Anabel
- Zhou  Xuanyu
- Zhussupov  Baurzhan
- Zijaj  Lorena
- Zimmelman  Natalie
- Zmora  Oded
- Zmora  Oded
- Zohra  Belabbes Fatima
- Publication venue
- HAL CCSD
- Publication date
- 01/11/2021
- Field of study
We aimed to determine the impact of pre-operative isolation on postoperative pulmonary complications after elective surgery during the global SARS-CoV-2 pandemic. We performed an international prospective cohort study including patients undergoing elective surgery in October 2020. Isolation was defined as the period before surgery during which patients did not leave their house or receive visitors from outside their household. The primary outcome was postoperative pulmonary complications, adjusted in multivariable models for measured confounders. Pre-defined sub-group analyses were performed for the primary outcome. A total of 96,454 patients from 114 countries were included and overall, 26,948 (27.9%) patients isolated before surgery. Postoperative pulmonary complications were recorded in 1947 (2.0%) patients of which 227 (11.7%) were associated with SARS-CoV-2 infection. Patients who isolated pre-operatively were older, had more respiratory comorbidities and were more commonly from areas of high SARS-CoV-2 incidence and high-income countries. Although the overall rates of postoperative pulmonary complications were similar in those that isolated and those that did not (2.1% vs 2.0%, respectively), isolation was associated with higher rates of postoperative pulmonary complications after adjustment (adjusted OR 1.20, 95%CI 1.05â1.36, p = 0.005). Sensitivity analyses revealed no further differences when patients were categorised by: pre-operative testing; use of COVID-19-free pathways; or community SARS-CoV-2 prevalence. The rate of postoperative pulmonary complications increased with periods of isolation longer than 3 days, with an OR (95%CI) at 4â7 days or â„ 8 days of 1.25 (1.04â1.48), p = 0.015 and 1.31 (1.11â1.55), p = 0.001, respectively. Isolation before elective surgery might be associated with a small but clinically important increased risk of postoperative pulmonary complications. Longer periods of isolation showed no reduction in the risk of postoperative pulmonary complications. These findings have significant implications for global provision of elective surgical care. We aimed to determine the impact of pre-operative isolation on postoperative pulmonary complications after elective surgery during the global SARS-CoV-2 pandemic. We performed an international prospective cohort study including patients undergoing elective surgery in October 2020. Isolation was defined as the period before surgery during which patients did not leave their house or receive visitors from outside their household. The primary outcome was postoperative pulmonary complications, adjusted in multivariable models for measured confounders. Pre-defined sub-group analyses were performed for the primary outcome. A total of 96,454 patients from 114 countries were included and overall, 26,948 (27.9%) patients isolated before surgery. Postoperative pulmonary complications were recorded in 1947 (2.0%) patients of which 227 (11.7%) were associated with SARS-CoV-2 infection. Patients who isolated pre-operatively were older, had more respiratory comorbidities and were more commonly from areas of high SARS-CoV-2 incidence and high-income countries. Although the overall rates of postoperative pulmonary complications were similar in those that isolated and those that did not (2.1% vs 2.0%, respectively), isolation was associated with higher rates of postoperative pulmonary complications after adjustment (adjusted OR 1.20, 95%CI 1.05â1.36, p = 0.005). Sensitivity analyses revealed no further differences when patients were categorised by: pre-operative testing; use of COVID-19-free pathways; or community SARS-CoV-2 prevalence. The rate of postoperative pulmonary complications increased with periods of isolation longer than 3 days, with an OR (95%CI) at 4â7 days or â„ 8 days of 1.25 (1.04â1.48), p = 0.015 and 1.31 (1.11â1.55), p = 0.001, respectively. Isolation before elective surgery might be associated with a small but clinically important increased risk of postoperative pulmonary complications. Longer periods of isolation showed no reduction in the risk of postoperative pulmonary complications. These findings have significant implications for global provision of elective surgical care
Evaluation of a quality improvement intervention to reduce anastomotic leak following right colectomy (EAGLE): pragmatic, batched stepped-wedge, cluster-randomized trial in 64 countries
- Author
- Aarts Frits
- Ababneh Hazim
- Abad-Motos Ane
- Abaidalla Ahmed
- Abbakar Malaz
- Abd El Aal Ahmed
- Abd-Errazik Mohammad Ahmad
- Abdalradiy Abdalrahmman G
- Abdelkhalek Mohamed
- Abdelkhalek Mostafa
- Abdellatif Ahmed
- Abdellatif Mohamed
- Abdelsaid Kirolas
- Abdou Khaled
- Abdulfatah Mustapha
- Abdullah Mohammad Amer
- Abdullahi Mustapha Miko Mohammed
- AbellĂĄn Antonio Melero
- Abeysinghe Nayana
- Abiyere Henry
- Achimas-Cadariu Patriciu Andrei
- Adakaya Sıla
- Adam Nicolas
- Adams Benita
- Adams Ferdinand
- Adegboye Kazeem
- Adeyeye Ademola
- Adra Lama
- Adu-Poku Patricia
- Afuwape Oludolapo
- Afzal Ameer
- Afzal Muhammad Farooq
- Agapov Mihail
- Agara Daniel
- Aggarwal Manisha
- Agger Erika
- Aghadi Ifeanyi Kene
- Ahmed Amjed Yassir
- Ahmed Haleemasahdia
- Ahmed Khalil
- Ahmed Manar
- Ahmed Masood
- Ahmed Safia
- Ahn Hong Min
- Aibe Raquel
- Aigner Felix
- Aissat Abdenour
- Aitbaeva Arai
- Akay Omer
- Akbar Ali
- Akbas Ahmet
- Akere Abidemi
- Akesen Selcan
- Akgun Erhan
- Akhtar Naseem
- Akın Emrah
- Akova Elif
- Aktas Serhat
- Akçay Ăzlem
- Al Masri Mahmoud
- Al-Alnsi Ahmed
- Al-Hutheifi Roqia'A
- Al-Jarrah Amar
- Al-Naggar Hamza
- Al-Shehari Mohammed
- Alamin Nadeen
- Alawi Raneen
- Alawlaqi Dina
- Alawneh Fade
- Alberola Maria José
- Albers Michael
- Alcolea Natalia GonzĂĄlez
- Aleem Muhammad
- Alegre InĂȘs
- Alegre Javier Martinez
- Alexandre Flavia
- Alexandrescu Corina
- Alexnder Abelevich
- Alexopoulou Kalliopi
- Alfonso Beatriz AmorĂłs
- Ali Ahmed
- Ali Che Saniati Che
- Ali Danish
- Ali Madeeha
- Ali Mahmoud Abdelwahab
- Ali Manhal Hashim
- Ali Noura Al
- Alikhanli Jhale
- Aliyeva Zumrud
- Aliyu Mohammed
- Aljawder Hasan
- Allen Kate
- Almahmeed Ebrahim
- Alonso Alfredo
- Alonso Javier Etreros
- Alsamneh Muneer
- Alsayadi Ramzi
- Altinel Yuksel
- Altintoprak Fatih
- Altomare Donato F
- Alvarenga Isabella
- Alvarez Laura Jimenez
- Alvarez-Bautista Francisco Emmanuel
- Alvarez-DĂez Marcos
- Alves Brenda Chayanny
- Amadigwe Rita
- Amado Andreia
- Amado FabĂola
- Amador Cristina GarcĂa
- Amanullah Nazli
- Amaral HĂ©lida Aline Tomacheski
- Amaral Luis
- Amin-Tai Hizami
- Aminu Bashiru
- Amir Ahmad Suhaimi
- Ammar Ahmed Siddique
- Ammar Mona Ahmed
- Ammendola Michele
- Ammerata Giorgio
- Amorim Edgar
- Ancans Guntis
- Anderson Tom
- Andrade Diogo
- Andrejevic Predrag
- AndrĂ©s Beatriz DĂaz San
- Anestiadou Elissavet
- Ang Chin Wee
- Angelo Franceschi
- Anokhin Evgeny
- Anoldo Pietro
- Antakia Ramez
- Anton Majd
- Antonelli Serena
- Antropoli Carmine
- Anula Rocio
- Anwar Jamal
- Anyadike Florence
- Apostolakidou Magda
- Apostolidi Eirini
- Aprea Giovanni
- Arabadzhiev Angel
- Arakawa Satoshi
- Arauz Jazmin
- Aravindan U
- Aremu Abdurrahman
- Aremu Isiaka
- Argawy Osama
- Arican Can
- Arida Zahed Abu
- Armellin Claudia
- Arnaoutoglou Eleni
- Arreguy-Borges Kanthya
- Artigot Mariano
- Arturi Alessandro
- Arulappan Nirupama
- Arya Shobhit
- Arynov Ardak
- Asaad Peter
- Asano Yukio
- Ascari Francesca
- Asgarov Mohsum
- Ashmawy Soad
- Aslam Muhammad Imran
- Assimakopoulou Elena
- Assis Ana
- Astilleta Romina
- Atanasov Boyko
- Atendido Tiffany
- Athanasakis Elias
- Atici Semra Demirli
- Avellaneda Nicholas
- Avellaneda Nicolas
- Avseren Goksu
- Awead Marwa
- Ayandipo Omobolaji
- Aybar Engin
- Aydin Funda
- Aydin Gaye
- Ayoub Kusay
- Aytac Erman
- Aytaç Erman
- Azevedo Jose
- Azevedo Patricia
- Azhar Najia
- Aziz Gowhar
- Azman Zairul Azwan Mohd
- AĆkar Ahmet
- Babatunde Olanrewaju
- Badawi Marwa
- Baek Jeong-Heum
- Baez Noelia FernĂĄndez
- Baeza-Murcia Melody
- Bagnardi Francesco
- Baharom Salahudin
- Baik Seung Hyuk
- Baimakhanov Abylai
- Bains Lovenish
- Baker Aleksandra
- Bakmaz Bernarda
- Bala Abubakar Muhammad
- Balaban Vladimir
- Balalis Dimitrios
- Balasubramaniam Dinesh
- Balathayalan Yathev
- Baldi Claudio
- Balestri Riccardo
- Balfour James
- Ballah Abubakar
- Ballian Nikiforos
- Balooshi Iman Al
- Baloyiannis Ioannis
- Bamford Richard
- Bandar Mahdi Al
- Banham Gail
- Bannoud Mohammad Hassan
- Baptista Victor
- Baral Jörg
- Barbalace Nicolas
- Barbato Giuseppe
- Barbosa Anderson
- Bareka Metaxia
- Baris Baver
- Barradas Renato
- Barreda Sara Castillo
- Barrena-Blazquez Silvestra
- Barton Jess
- Bartosiak Katarzyna
- Bashilkina Olga
- Bashir Mohammed
- Basile Raffaele
- Basnyat Pradeep
- Batool Sana
- Bautista Wilson Manuel SĂĄnchez
- Bayhan ZĂŒlfĂŒ
- Bayo José Manuel Muros
- BayĂłn Raquel Ălvaro
- Baños Pedro Antonio Parra
- Beard David
- Bedzhanyan Arkady
- Behilil Chakib
- Bekele Kebebe
- Belarmino Armin
- Belay Million
- Belev Nikolay
- Bellato Vittoria
- BeltrĂĄn de Heredia Juan
- Belvedere Angela
- Benetti Emilio
- Benetti Sara
- Bengueddach Aicha
- Benjelloun El Bachir
- Benkabbou Amine
- Bennett James
- Bensafir Salim
- Bergamini Carlo
- Bernotaite Vlada
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- Zain Wan Zainira Wan
- Zainy Rhendra Hardy Mohamad
- Zakaria Andee Dzulkarnaen
- Zakaria Maheen
- Zakaria Zaidi
- Zamudio-Bautista Jorge Luis
- Zanc Loredana
- Zanoni Andrea
- Zanus Giacomo
- Zapparoli Alessandro
- Zappone Anna
- Zarzava Eirini
- Zatari Dirar
- Zawadzki Marek
- Zayakov Georgi
- Zaycev Andrey
- Zazo Aya
- Zazo Rama
- Zdravkovic Maja
- Zengin Abdullah KaÄan
- Zeringa Georgia
- Zimmerman David D E
- Zuhdy Mohammad
- Zvirych Vitalii
- Zywicka Ewa
- Ălvarez-Llano Laura
- Ăngelo Miguel Duarte
- ĂSullivan Sara Nuñez
- Ăzçelik Mehmet Faik
- Äoza Ivo
- Ćanlı Ahmet Necati
- Publication venue
- Publication date
- 01/01/2023
- Field of study
Background
Anastomotic leak affects 8 per cent of patients after right colectomy with a 10-fold increased risk of postoperative death. The EAGLE study aimed to develop and test whether an international, standardized quality improvement intervention could reduce anastomotic leaks.
Methods
The internationally intended protocol, iteratively co-developed by a multistage Delphi process, comprised an online educational module introducing risk stratification, an intraoperative checklist, and harmonized surgical techniques. Clusters (hospital teams) were randomized to one of three arms with varied sequences of intervention/data collection by a derived stepped-wedge batch design (at least 18 hospital teams per batch). Patients were blinded to the study allocation. Low- and middle-income country enrolment was encouraged. The primary outcome (assessed by intention to treat) was anastomotic leak rate, and subgroup analyses by module completion (at least 80 per cent of surgeons, high engagement; less than 50 per cent, low engagement) were preplanned.
Results
A total 355 hospital teams registered, with 332 from 64 countries (39.2 per cent low and middle income) included in the final analysis. The online modules were completed by half of the surgeons (2143 of 4411). The primary analysis included 3039 of the 3268 patients recruited (206 patients had no anastomosis and 23 were lost to follow-up), with anastomotic leaks arising before and after the intervention in 10.1 and 9.6 per cent respectively (adjusted OR 0.87, 95 per cent c.i. 0.59 to 1.30; P = 0.498). The proportion of surgeons completing the educational modules was an influence: the leak rate decreased from 12.2 per cent (61 of 500) before intervention to 5.1 per cent (24 of 473) after intervention in high-engagement centres (adjusted OR 0.36, 0.20 to 0.64; P < 0.001), but this was not observed in low-engagement hospitals (8.3 per cent (59 of 714) and 13.8 per cent (61 of 443) respectively; adjusted OR 2.09, 1.31 to 3.31).
Conclusion
Completion of globally available digital training by engaged teams can alter anastomotic leak rates. Registration number: NCT04270721 (http://www.clinicaltrials.gov)