39 research outputs found
Albumin Is a Component of the Esterase Status of Human Blood Plasma
open access articleThe esterase status of blood plasma can claim to be one of the universal markers of various
diseases; therefore, it deserves attention when searching for markers of the severity of COVID-19
and other infectious and non-infectious pathologies. When analyzing the esterase status of blood
plasma, the esterase activity of serum albumin, which is the major protein in the blood of mammals,
should not be ignored. The purpose of this study is to expand understanding of the esterase status
of blood plasma and to evaluate the relationship of the esterase status, which includes information
on the amount and enzymatic activity of human serum albumin (HSA), with other biochemical
parameters of human blood, using the example of surviving and deceased patients with confirmed
COVID-19. In experiments in vitro and in silico, the activity of human plasma and pure HSA towards
various substrates was studied, and the effect of various inhibitors on this activity was tested. Then,
a comparative analysis of the esterase status and a number of basic biochemical parameters of the
blood plasma of healthy subjects and patients with confirmed COVID-19 was performed. Statistically
significant differences have been found in esterase status and biochemical indices (including albumin
levels) between healthy subjects and patients with COVID-19, as well as between surviving and
deceased patients. Additional evidence has been obtained for the importance of albumin as a
diagnostic marker. Of particular interest is a new index, [Urea] x [MDA] x 1000/(BChEb x [ALB]),
which in the group of deceased patients was 10 times higher than in the group of survivors and
26 times higher than the value in the group of apparently healthy elderly subjects
Production Asymmetry Measurement of High Xt Hadrons in pp Collisions at 40 GeV
Single-spin asymmetries for hadrons have been measured in collisions of
transversely-polarized 40 GeV/c proton beam with an unpolarized liquid hydrogen
target. The asymmetries were measured for pi+-, K+-, protons and antiprotons,
produced in the central region (0.02 < Xf < 0.10 and 0.7 < Pt < 3.4 GeV/c).
Asymmetries for pi+-, K+- and antiprotons show within measurement errors the
linear dependence on Xt and change a sign near 0.37. For protons negative
asymmetry, independent of Xt has been found. The results are compared with
those of other experiments and SU(6) model predictions.Comment: 25 pages (Latex), 12 Postscript figure
Studies of the Response of the Prototype CMS Hadron Calorimeter, Including Magnetic Field Effects, to Pion, Electron, and Muon Beams
We report on the response of a prototype CMS hadron calorimeter module to
charged particle beams of pions, muons, and electrons with momenta up to 375
GeV/c. The data were taken at the H2 and H4 beamlines at CERN in 1995 and 1996.
The prototype sampling calorimeter used copper absorber plates and scintillator
tiles with wavelength shifting fibers for readout. The effects of a magnetic
field of up to 3 Tesla on the response of the calorimeter to muons, electrons,
and pions are presented, and the effects of an upstream lead tungstate crystal
electromagnetic calorimeter on the linearity and energy resolution of the
combined calorimetric system to hadrons are evaluated. The results are compared
with Monte Carlo simulations and are used to optimize the choice of total
absorber depth, sampling frequency, and longitudinal readout segmentation.Comment: 89 pages, 41 figures, to be published in NIM, corresponding author: P
de Barbaro, [email protected]
Evidence of Color Coherence Effects in W+jets Events from ppbar Collisions at sqrt(s) = 1.8 TeV
We report the results of a study of color coherence effects in ppbar
collisions based on data collected by the D0 detector during the 1994-1995 run
of the Fermilab Tevatron Collider, at a center of mass energy sqrt(s) = 1.8
TeV. Initial-to-final state color interference effects are studied by examining
particle distribution patterns in events with a W boson and at least one jet.
The data are compared to Monte Carlo simulations with different color coherence
implementations and to an analytic modified-leading-logarithm perturbative
calculation based on the local parton-hadron duality hypothesis.Comment: 13 pages, 6 figures. Submitted to Physics Letters
Search for electroweak production of single top quarks in collisions.
We present a search for electroweak production of single top quarks in the electron+jets and muon+jets decay channels. The measurements use ~90 pb^-1 of data from Run 1 of the Fermilab Tevatron collider, collected at 1.8 TeV with the DZero detector between 1992 and 1995. We use events that include a tagging muon, implying the presence of a b jet, to set an upper limit at the 95% confidence level on the cross section for the s-channel process ppbar->tb+X of 39 pb. The upper limit for the t-channel process ppbar->tqb+X is 58 pb. (arXiv
Helicity of the W Boson in Lepton+Jets ttbar Events
We examine properties of ttbar candidates events in lepton+jets final states
to establish the helicities of the W bosons in t->W+b decays. Our analysis is
based on a direct calculation of a probability that each event corresponds to a
ttbar final state, as a function of the helicity of the W boson. We use the 125
events/pb sample of data collected by the DO experiment during Run I of the
Fermilab Tevatron collider at sqrt{s}=1.8 TeV, and obtain a longitudinal
helicity fraction of F_0=0.56+/-0.31, which is consistent with the prediction
of F_0=0.70 from the standard model
Hard Single Diffraction in pbarp Collisions at root-s = 630 and 1800 GeV
Using the D0 detector, we have studied events produced in proton-antiproton
collisions that contain large forward regions with very little energy
deposition (``rapidity gaps'') and concurrent jet production at center-of-mass
energies of root-s = 630 and 1800 Gev. The fractions of forward and central jet
events associated with such rapidity gaps are measured and compared to
predictions from Monte Carlo models. For hard diffractive candidate events, we
use the calorimeter to extract the fractional momentum loss of the scattered
protons.Comment: 11 pages 4 figures. submitted to PR