Catálisis en el Centro Conjunto de Investigación en Química Sustentable, uaem-unam*

Describimos aquí las actividades de investigación en el área de catálisis realizadas por algunas investigadoras de la Facultad de Química de la Universidad Autónoma del Estado de México, adscritas al Centro Conjunto de Investigación en Química Sustentable, uaem-unam. Se incluyen las líneas de investigación que desarrollan, las contribuciones que han generado y los logros en este campo obtenidos en los últimos años. También se presenta información sobre la infraestructura con que se cuenta en el cciqs y en la Facultad de Química para llevar a cabo investigación sobre catálisis; la importancia que tienen los trabajos de colaboración nacional e internacional, así como, la formación de recursos humanos altamente especializados en esta área. Por último, presentamos las perspectivas de investigación y desarrollo planteadas para el campo de la catálisis

Intervención breve en mujeres con discapacidad: em-poderándose ante el dolor

El dolor crónico suele ser de difícil tratamiento dado que después de un consumo prolongado analgésicos estos suelen dejar de funcionar como al principio, generando problemas secundarios como afecciones del sistema digestivo, dependencia e incluso aumento del dolor. Además de ello, suele ser una condición limitante para la vida y suele reducir su calidad significativamente. Muchas personas incluso terminan diseñando su vida alrededor del dolor para evitarlo o sentirlo lo menos posible, lo cual termina siendo una trampa pues el dolor crónico usualmente nunca se desaparece. En los últimos años se ha empezado introducir otro tipo de tratamientos que ayuden a manejar el dolor crónico como la fisioterapia, la medicina alternativa, la actividad física y las terapias psicológicas; las dos últimas han demostrado ser bastante efectivas en el manejo del dolor y más aun si se utilizan de manera combinada. Esta investigación pretendió mediante una intervención breve con la Terapia de Aceptación y Compromiso (ACT) mantener o aumentar la actividad física de mujeres con discapacidad y dolor crónico. Para ello se trabajó con 4 mujeres, 2 fueron asignadas al grupo experimental y las otras 2 al grupo control. Se hizo una medición pre-pos y de seguimiento al mes de finalizada la intervención de la aceptación del dolor crónico y las estrategias de afrontamiento y se registró la actividad física que realizaron durante toda la investigación. Se observan algunos cambios en las tres variables medidas que pueden sugerir que ACT influyó positivamente en su cambio. Sugerencias para próximas investigaciones son discutida

Discovery of Infection Associated Metabolic Markers in Human African Trypanosomiasis

Peer reviewedPublisher PD

Metabolic risk score indexes validation in overweight healthy people

The constellation of adverse cardiovascular disease (CVD) and metabolic risk factors, including elevated abdominal obesity, blood pressure (BP), glucose, and triglycerides (TG) and lowered high-density lipoprotein-cholesterol (HDL-C), has been termed the metabolic syndrome (MetSyn) [1]. A number of different definitions have been developed by the World Health Organization (WHO) [2], the National Cholesterol Education Program Adult Treatment Panel III (ATP III) [3], the European Group for the Study of Insulin Resistance (EGIR) [4] and, most recently, the International Diabetes Federation (IDF) [5]. Since there is no universal definition of the Metabolic Syndrome, several authors have derived different risk scores to represent the clustering of its components [6-11]

Do You Have Social Profile? Users And Non-Users Of Social Networking Sites In The Web 2.0

In light of the increasing importance of Social Networking Sites (SNSs) for both personal and professional relationships, the aim of this work is to contribute to the knowledge framework regarding the interactive behaviour of Internet users, particularly within Web 2.0, describing its evolution from Web 1.0. Moreover, this paper analyses the different behaviours on the Web by people who use or not use SNSs, as well as to determine whether any such differences are significant in order to discover the reasons why these people participate. As results, initial characterization of the users themselves is followed by an analysis of the main differences between users and non-users of these applications. With this information, companies can play an active role in this Social Web by becoming company 2.0 and participating actively in already existing SNSs or creating their own social network service

Paracetamol mineralization by Photo Fenton process catalyzed by a Cu/Fe- PILC under circumneutral pH conditions

This study presents an iron-pillared clay (Fe-PILC) ion-exchanged with copper (Cu/Fe-PILC), as an efficient catalyst to conduct the mineralization of paracetamol through photo-Fenton process at near to neutral pH without precipitation of Fe complexes and without adding any chemicals to modify the initial pH. The specific surface area of the catalyst was of 110m2 g−1 and with the following phases FeO, Fe3O4, Cu2O, CuO determined by XPS analyses. Around 80% of mineralization was reached either by conducting the process at acidic and circumneutral pH conditions, and the efficiency was not significantly higher at pH=2.7. The intermediate reaction products generated at both pH conditions essayed and detected by LC–MS were hydroquinone, acetamide and oxamic acid. Catalyst Cu/Fe-PILC showed an iron leaching of about 3% after reaction while the reusability of the catalyst involved a decrease in mineralization of only 3% under circumneutral conditions. The final TOC of about 20% can be ascribed to the presence of acetamide that was found to be the most reluctant towards oxidation.CONACYT 269093 PRODEP (511-6/178590) CONACYT (Estancia sabática) 26614

Plan de optimización de los procesos de abastecimiento y gestión de estrategias financieras en la empresa isuzu remanufactura de Colombia SAS

Esta monografía está compuesta por cuatro capítulos, en el primero se dan a conocer aspectos generales de la compañía Isuzu Remanufactura de Colombia S.A.S (IRC), partiendo de sus inicios, su portafolio de productos, sus clientes, sus principales proveedores, competencia, entorno económico y su manera de operar. El segundo capítulo expone la situación financiera de IRC, a través de un análisis cuantitativo de los estados financieros, el cual pondrá en evidencia los aspectos a gestionar para lograr la optimización de los recursos. En el tercero mostrará un análisis cualitativo y se establecerá un procedimiento para el proceso de abastecimiento de IRC, definiendo el rol y alcance de cada una de las áreas que participan en la cadena de suministro de la compañía. En una cuarta sección se desarrollarán las estrategias financieras diseñadas a partir del diagnóstico hecho de la situación financiera actual de la compañía, dichas estrategias serán proyectadas a cinco años. En el quinto capítulo, se evaluará la rentabilidad y conveniencia de incluir un nuevo producto en el portafolio, que impulse el crecimiento en ventas y rentabilidad de la organización. En el último capítulo, se plasmara el análisis cuantitativo de los estados Financieros con estrategias, definiendo así la valoración de IRC con esta implementación y sus efectos en el Price Book Value

Web 2.0 Tools In Retailing: Benefits Of Their Use And Reasons For Not Using Them

The term Web 2.0 was introduced by O’Reilly (2005) as the new stage in the Internet evolution referring to a collection of online applications sharing a number of common characteristics: “The Web as a platform, Harnessing of the Collective Intelligence, Data is the Next Intel Inside, End of the Software Release Cycle, Lightweight Programming Models, Rich User Experiences”. The term Web 2.0 or Social Media refers to applications enabling the creation, editing and dissemination of user-generated content. These applications are one of the main components of the current Internet environment commonly called Web 2.0. The importance and popularity of the Social Media as marketing tools and communication channels is growing and field studies provide evidence that these can strongly affect consumer behavior. An increasing number of studies suggest that corporate interest on the Web 2.0 domain keeps growing and more and more firms are introducing different social media tools into their daily business routines as well as into their marketing strategies. Despite the fact that thousands of corporations are already seriously engaged or experimenting with the Social Media as marketing tools there is also a high amount of retailers that do not use them. The objective of this study is to analyze the reasons why retailers do not use Web 2.0 tools and the main barriers that they consider to not adopt them, comparing with the retailers that use these tools

Mitochondrial dysfunction, lipids metabolism, and amino acid biosynthesis are key pathways for COVID-19 recovery

Biological sciences; Human metabolismCiències biològiques; Metabolisme humàCiencias biológicas; Metabolismo humanoThe metabolic alterations caused by SARS-CoV-2 infection reflect disease progression. To analyze molecules involved in these metabolic changes, a multiomics study was performed using plasma from 103 patients with different degrees of COVID-19 severity during the evolution of the infection. With the increased severity of COVID-19, changes in circulating proteomic, metabolomic, and lipidomic profiles increased. Notably, the group of severe and critical patients with high HRG and ChoE (20:3) and low alpha-ketoglutaric acid levels had a high chance of unfavorable disease evolution (AUC = 0.925). Consequently, patients with the worst prognosis presented alterations in the TCA cycle (mitochondrial dysfunction), lipid metabolism, amino acid biosynthesis, and coagulation. Our findings increase knowledge regarding how SARS-CoV-2 infection affects different metabolic pathways and help in understanding the future consequences of COVID-19 to identify potential therapeutic targets.This work has been developed in the framework of the COVIDOMICS’ project supported by Direcció General de Recerca i Innovació en Salut (DGRIS), Departament de Salut, Generalitat de Catalunya (PoC-6-17 and PoC1-5). The research was also supported by the Programa de Suport als Grups de Recerca AGAUR (2021SGR01404), the SPANISH AIDS Research Network [RD16/0025/0006]-ISCIII-FEDER (Spain) and the CIBER -Consorcio Centro de Investigación Biomédica en Red- (CB21/13/00020 and CB07/08/0012), Instituto de Salud Carlos III, Ministerio de Ciencia e Innovación and Unión Europea – NextGenerationEU. FV is supported by grants from the Programa de Intensificación de Investigadores (INT20/00031)-ISCIII and by “Premi a la Trajectòria Investigadora dels Hospitals de l’ICS 2018”. AR is supported by a grant from IISPV through the project “2019/IISPV/05” (Boosting Young Talent), by GeSIDA through the “III Premio para Jóvenes Investigadores 2019” and by the Instituto de Salud Carlos III (ISCIII) under grant agreement “CP19/00146” through the Miguel Servet Program. Finally, this study would not have been possible without the generous collaboration of all the patients and their families and medical and nursing staff who have taken part in the project. We particularly acknowledge the collaboration of the Departments of Preventive Medicine and Epidemiology, Internal Medicine, Critical Care, Emergency, Occupational Health, Laboratory Medicine and Molecular Biology, and BioBank-IISPV (B.0000853 + B.0000854) integrated into the Spanish National Biobanks Platform (PT20/00197), CERCA Program (Generalitat de Catalunya) and IISPV, for their collaboration

Selective production of Dihydroxyacetone and Glyceraldehyde by Photo-assisted Oxidation of Glycerol

Glycerol is a by-product during biodiesel production and represents a potential low-cost raw material for obtaining high-cost products like Dihydroxyacetone (DHA) and glyceraldehyde (GCD) amongst others. In this work, Fe-Pillared clay (Fe-PILC) was assessed as catalyst of the selective photo-oxidation of glycerol to obtain DHA and GCD at moderate conditions (298 K and atmospheric pressure). This was conducted in a 100 mL Pyrex glass batch reactor where a Pen-Ray lamp of mercury of 5.5 Watts UV light (UVP) was placed at the centre. The Fe-PILC was prepared by ion exchange. The pillaring was confirmed by XRD, and a 17% w/w of Fe was determined by Atomic Absorption Spectroscopy. The active phases were established by XPS and found to be FeO and Fe3O4. The specific surface area of the clay (bentonite), determined by N2 physisorption, increased from 34 m2/g to 227 m2/g and the pore volume increased from 0.058 cm3/g to 0.106 cm3/g. The studied variables were catalyst loading and glycerol initial concentration. An experiment with TiO2 Degussa P25 was also performed as reference. It was found that by adding Fe-PILC to the glycerol oxidation system, selectivity towards DHA or GCD can be tuned. A selectivity towards DHA was found to be 87% with 0.1 g/L of Fe-Pillared after 8 h reaction. The in situ production ofH2O2 was observed and therefore concluded that the glycerol oxidation occurs via a Fenton process, i.e. via free radicals.CONAYCT project 269093 UAEM project 437