Memory portraits: analysis of documentary photographs of families of femicide victims (Jujuy-Argentina)

El artículo se sitúa en la confluencia disciplinar entre antropología, estudios de género y de memoria. Se busca recuperar diversas historias en clave fotográfica, de familiares de víctimas de femicidio de la provincia de Jujuy, situada al extremo norte de Argentina. De tal manera, el uso de la imagen marca el derrotero del análisis etnográfico y se transforma en el medio propicio para evidenciar las memorias de dolor de las familias de las víctimas. Se analizaron cincuenta fotografías de campo y veinte fotografías obtenidas en portales web de diarios locales y nacionales. Por tanto no se usa la fotografía en clave de objeto artístico sino documental. Entre las conclusiones principales se destaca la centralidad de comprender a las y los familiares de víctimas de femicidio como víctimas colaterales. El uso de las fotografías, como fuente de conocimiento antropológico, permitió observar la consecuencia colectiva que la violencia patriarcal tiene en el entorno más directo de la víctima así como las trayectorias vitales que transforman su capacidad de comunicar(se) el dolorThis article is situated at the disciplinary crossroads among anthropology, gender and memory studies. It seeks to recover, through the use of photographs, various stories of relatives of victims of femicide in the province of Jujuy, located in the north of Argentina. In doing so, the incorporation of images leads the ethnographic analysis, and becomes the conducive means whereby the memories of pain of the families of the victims are highlighted. Fifty fieldwork photographs and twenty photographs obtained online from local and national newspapers were analyzed. Therefore, photography is not used as an artistic object but as a documentary one. Among the main conclusions, the centrality of understanding the relatives of victims of femicide as collateral victims stands out. The use of photographs as a source of anthropological knowledge allowed observing the collective consequences that patriarchal violence has in the most direct environment of the victim is stated as well as vital trajectories that transform their ability to communicate their pain.Fil: Gomez, Carina Elizabeth. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Unidad Ejecutora en Ciencias Sociales Regionales y Humanidades. Universidad Nacional de Jujuy. Unidad Ejecutora en Ciencias Sociales Regionales y Humanidades; Argentin

“The conditions of/on my sex”: Argentina women scientists against masculinised memory

Este trabajo tiene como fin presentar el panorama social que rodeó el ingreso de las mujeres al ámbito académico universitario argentino en tanto acontecimiento histórico mediado por las relaciones de género. Se describe el contexto social en las postrimerías del siglo XIX y principios del XX en Argentina a partir de la configuración normativa así como la descripción de sucesos que buscaron irrumpir con el encierro doméstico femenino. Se examina el acceso femenino a la educación universitaria y los estudios científicos en el contexto argentino de principio del siglo XX cuando se registran los primeros trabajos de investigación de mujeres en las publicaciones científicas. Entramado a este contexto se describe la vida de Prosperina Paraván, una estudiante figura clave femenina en los sucesos de la Reforma Universitaria. Estos acontecimientos históricos son recordados desde la óptica masculina, subvalorando y relegando al olvido la insumisión de aquellas mujeres en las universidades argentinas.This work aims to present the social atmosphere surrounding women´s admission to Argentinian university academic sphere as a historical event mediated by gender relations. The social context in late 20th and early 21st centuries in Argentina is also described, as regards its normative frame as well as the events which broke into female domestic confinement and women´s difficulties to access education. Furthermore, women's access to university education and scientific studies is examined in the Argentinian historical context of early 20th century, when the first women's research papers are registered. Within this context Prosperina Paravarán´s life is described. She was a Santafecina student of the Dentistry programme at the National University of Córdoba who actively participated in the events during the University Reform, thus becoming a prominent female figure. Even after women's admission to universities, the University Reform was redrafted from a male perspective, underestimating those pioneer women´s unsubmitting attitude in Argentinian universities and consigning them to oblivion.Fil: Gomez, Carina Elizabeth. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Unidad Ejecutora en Ciencias Sociales Regionales y Humanidades. Universidad Nacional de Jujuy. Unidad Ejecutora en Ciencias Sociales Regionales y Humanidades; Argentin

“Las condiciones de mi sexo”: Mujeres científicas argentinas frente a la memoria masculinizada

Este trabajo tiene como fin presentar el panorama social que rodeó el ingreso de las mujeres al ámbito académico universitario argentino en tanto acontecimiento histórico mediado por las relaciones de género. Se describe el contexto social en las postrimerías del siglo XIX y principios del XX en Argentina a partir de la configuración normativa así como la descripción de sucesos que buscaron irrumpir con el encierro doméstico femenino. Se examina el acceso femenino a la educación universitaria y los estudios científicos en el contexto argentino de principio del siglo XX cuando se registran los primeros trabajos de investigación de mujeres en las publicaciones científicas. Entramado a este contexto se describe la vida de Prosperina Paraván, una estudiante figura clave femenina en los sucesos de la Reforma Universitaria. Estos acontecimientos históricos son recordados desde la óptica masculina, subvalorando y relegando al olvido la insumisión de aquellas mujeres en las universidades argentinas.Fil: Gomez, Carina Elizabeth. CONICET. Unidad Ejecutora en Ciencias Sociales Regionales y Humanidades; Argentina

“Myth-Busting”: On reflexivity as a bridge between research and extension

En este texto reflexionamos sobre nuestros inicios como grupo extensionista de la Universidad Nacional de Jujuy. Exponemos cómo, tras participar en un evento de vinculación basado en una lógica de transferencia y no de intercambio, nos propusimos lanzar un proyecto que superara dicho razonamiento desde una perspectiva extensionista crítica. Identificando la reflexividad como aquel puente que nos permitiría atravesar las distancias entre cada una de nuestras investigaciones y el campo de la extensión: (1) presentamos el proceso colectivo e institucional que seguimos para poner en marcha el proyecto que denominamos ?Cazando mitos: acercando la investigación en ciencias sociales a escuelas secundarias de San Salvador de Jujuy?, (2) contrastamos las experiencias que tuvimos en las aulas de tres centros educativos, y (3) evaluamos los logros y las limitaciones de la que fuera nuestra primera propuesta extensionista conjunta.In this paper we reflect on our beginnings as an extensionist group at the National University of Jujuy. We expose how, after participating in a university extension event based on a logic of transfer and not of exchange, we decided to create a project with which to overcome this rationale from a critical extensionist perspective. Identifying reflexivity as that bridge that would allow us to cross the distances between each of our researches and the field of extension: (1) we present the collective and institutional process we followed to launch “Myth-Busting: Bringing social sciences research closer to secondary schools in San Salvador de Jujuy”, (2) we contrast the experiences we had in the classrooms of three educational centers, and (3) we evaluate the achievements and limitations of that which was our first joint extension proposal.Fil: Gomez, Carina Elizabeth. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Unidad Ejecutora en Ciencias Sociales Regionales y Humanidades. Universidad Nacional de Jujuy. Unidad Ejecutora en Ciencias Sociales Regionales y Humanidades; ArgentinaFil: Patagua, Patricia Evangelina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Unidad Ejecutora en Ciencias Sociales Regionales y Humanidades. Universidad Nacional de Jujuy. Unidad Ejecutora en Ciencias Sociales Regionales y Humanidades; ArgentinaFil: Rovetta Cortes, Ana Irene. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Unidad Ejecutora en Ciencias Sociales Regionales y Humanidades. Universidad Nacional de Jujuy. Unidad Ejecutora en Ciencias Sociales Regionales y Humanidades; ArgentinaFil: Yufra, Laura Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Unidad Ejecutora en Ciencias Sociales Regionales y Humanidades. Universidad Nacional de Jujuy. Unidad Ejecutora en Ciencias Sociales Regionales y Humanidades; Argentin

Study of the B−→Λc+Λˉc−K−B^{-} \to \Lambda_{c}^{+} \bar{\Lambda}_{c}^{-} K^{-} decay

The decay $B^{-} \to \Lambda_{c}^{+} \bar{\Lambda}_{c}^{-} K^{-}$ is studied in proton-proton collisions at a center-of-mass energy of $\sqrt{s}=13$ TeV using data corresponding to an integrated luminosity of 5 $\mathrm{fb}^{-1}$ collected by the LHCb experiment. In the $\Lambda_{c}^+ K^{-}$ system, the $\Xi_{c}(2930)^{0}$ state observed at the BaBar and Belle experiments is resolved into two narrower states, $\Xi_{c}(2923)^{0}$ and $\Xi_{c}(2939)^{0}$, whose masses and widths are measured to be $$m(\Xi_{c}(2923)^{0}) = 2924.5 \pm 0.4 \pm 1.1 \,\mathrm{MeV}, \\ m(\Xi_{c}(2939)^{0}) = 2938.5 \pm 0.9 \pm 2.3 \,\mathrm{MeV}, \\ \Gamma(\Xi_{c}(2923)^{0}) = \phantom{000}4.8 \pm 0.9 \pm 1.5 \,\mathrm{MeV},\\ \Gamma(\Xi_{c}(2939)^{0}) = \phantom{00}11.0 \pm 1.9 \pm 7.5 \,\mathrm{MeV},$$ where the first uncertainties are statistical and the second systematic. The results are consistent with a previous LHCb measurement using a prompt $\Lambda_{c}^{+} K^{-}$ sample. Evidence of a new $\Xi_{c}(2880)^{0}$ state is found with a local significance of $3.8\,\sigma$, whose mass and width are measured to be $2881.8 \pm 3.1 \pm 8.5\,\mathrm{MeV}$ and $12.4 \pm 5.3 \pm 5.8 \,\mathrm{MeV}$, respectively. In addition, evidence of a new decay mode $\Xi_{c}(2790)^{0} \to \Lambda_{c}^{+} K^{-}$ is found with a significance of $3.7\,\sigma$. The relative branching fraction of $B^{-} \to \Lambda_{c}^{+} \bar{\Lambda}_{c}^{-} K^{-}$ with respect to the $B^{-} \to D^{+} D^{-} K^{-}$ decay is measured to be $2.36 \pm 0.11 \pm 0.22 \pm 0.25$, where the first uncertainty is statistical, the second systematic and the third originates from the branching fractions of charm hadron decays.Comment: All figures and tables, along with any supplementary material and additional information, are available at https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-028.html (LHCb public pages

Measurement of the ratios of branching fractions R(D∗)\mathcal{R}(D^{*}) and R(D0)\mathcal{R}(D^{0})

The ratios of branching fractions $\mathcal{R}(D^{*})\equiv\mathcal{B}(\bar{B}\to D^{*}\tau^{-}\bar{\nu}_{\tau})/\mathcal{B}(\bar{B}\to D^{*}\mu^{-}\bar{\nu}_{\mu})$ and $\mathcal{R}(D^{0})\equiv\mathcal{B}(B^{-}\to D^{0}\tau^{-}\bar{\nu}_{\tau})/\mathcal{B}(B^{-}\to D^{0}\mu^{-}\bar{\nu}_{\mu})$ are measured, assuming isospin symmetry, using a sample of proton-proton collision data corresponding to 3.0 fb${ }^{-1}$ of integrated luminosity recorded by the LHCb experiment during 2011 and 2012. The tau lepton is identified in the decay mode $\tau^{-}\to\mu^{-}\nu_{\tau}\bar{\nu}_{\mu}$. The measured values are $\mathcal{R}(D^{*})=0.281\pm0.018\pm0.024$ and $\mathcal{R}(D^{0})=0.441\pm0.060\pm0.066$, where the first uncertainty is statistical and the second is systematic. The correlation between these measurements is $\rho=-0.43$. Results are consistent with the current average of these quantities and are at a combined 1.9 standard deviations from the predictions based on lepton flavor universality in the Standard Model.Comment: All figures and tables, along with any supplementary material and additional information, are available at https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-039.html (LHCb public pages

Multidifferential study of identified charged hadron distributions in ZZ-tagged jets in proton-proton collisions at s=\sqrt{s}=13 TeV

Jet fragmentation functions are measured for the first time in proton-proton collisions for charged pions, kaons, and protons within jets recoiling against a $Z$ boson. The charged-hadron distributions are studied longitudinally and transversely to the jet direction for jets with transverse momentum 20 $< p_{\textrm{T}} < 100$ GeV and in the pseudorapidity range $2.5 < \eta < 4$. The data sample was collected with the LHCb experiment at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 1.64 fb$^{-1}$. Triple differential distributions as a function of the hadron longitudinal momentum fraction, hadron transverse momentum, and jet transverse momentum are also measured for the first time. This helps constrain transverse-momentum-dependent fragmentation functions. Differences in the shapes and magnitudes of the measured distributions for the different hadron species provide insights into the hadronization process for jets predominantly initiated by light quarks.Comment: All figures and tables, along with machine-readable versions and any supplementary material and additional information, are available at https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-013.html (LHCb public pages

Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial

Background: Glucagon-like peptide 1 receptor agonists differ in chemical structure, duration of action, and in their effects on clinical outcomes. The cardiovascular effects of once-weekly albiglutide in type 2 diabetes are unknown. We aimed to determine the safety and efficacy of albiglutide in preventing cardiovascular death, myocardial infarction, or stroke. Methods: We did a double-blind, randomised, placebo-controlled trial in 610 sites across 28 countries. We randomly assigned patients aged 40 years and older with type 2 diabetes and cardiovascular disease (at a 1:1 ratio) to groups that either received a subcutaneous injection of albiglutide (30–50 mg, based on glycaemic response and tolerability) or of a matched volume of placebo once a week, in addition to their standard care. Investigators used an interactive voice or web response system to obtain treatment assignment, and patients and all study investigators were masked to their treatment allocation. We hypothesised that albiglutide would be non-inferior to placebo for the primary outcome of the first occurrence of cardiovascular death, myocardial infarction, or stroke, which was assessed in the intention-to-treat population. If non-inferiority was confirmed by an upper limit of the 95% CI for a hazard ratio of less than 1·30, closed testing for superiority was prespecified. This study is registered with ClinicalTrials.gov, number NCT02465515. Findings: Patients were screened between July 1, 2015, and Nov 24, 2016. 10 793 patients were screened and 9463 participants were enrolled and randomly assigned to groups: 4731 patients were assigned to receive albiglutide and 4732 patients to receive placebo. On Nov 8, 2017, it was determined that 611 primary endpoints and a median follow-up of at least 1·5 years had accrued, and participants returned for a final visit and discontinuation from study treatment; the last patient visit was on March 12, 2018. These 9463 patients, the intention-to-treat population, were evaluated for a median duration of 1·6 years and were assessed for the primary outcome. The primary composite outcome occurred in 338 (7%) of 4731 patients at an incidence rate of 4·6 events per 100 person-years in the albiglutide group and in 428 (9%) of 4732 patients at an incidence rate of 5·9 events per 100 person-years in the placebo group (hazard ratio 0·78, 95% CI 0·68–0·90), which indicated that albiglutide was superior to placebo (p&lt;0·0001 for non-inferiority; p=0·0006 for superiority). The incidence of acute pancreatitis (ten patients in the albiglutide group and seven patients in the placebo group), pancreatic cancer (six patients in the albiglutide group and five patients in the placebo group), medullary thyroid carcinoma (zero patients in both groups), and other serious adverse events did not differ between the two groups. There were three (&lt;1%) deaths in the placebo group that were assessed by investigators, who were masked to study drug assignment, to be treatment-related and two (&lt;1%) deaths in the albiglutide group. Interpretation: In patients with type 2 diabetes and cardiovascular disease, albiglutide was superior to placebo with respect to major adverse cardiovascular events. Evidence-based glucagon-like peptide 1 receptor agonists should therefore be considered as part of a comprehensive strategy to reduce the risk of cardiovascular events in patients with type 2 diabetes. Funding: GlaxoSmithKline

Bi-allelic Loss-of-Function CACNA1B Mutations in Progressive Epilepsy-Dyskinesia.

The occurrence of non-epileptic hyperkinetic movements in the context of developmental epileptic encephalopathies is an increasingly recognized phenomenon. Identification of causative mutations provides an important insight into common pathogenic mechanisms that cause both seizures and abnormal motor control. We report bi-allelic loss-of-function CACNA1B variants in six children from three unrelated families whose affected members present with a complex and progressive neurological syndrome. All affected individuals presented with epileptic encephalopathy, severe neurodevelopmental delay (often with regression), and a hyperkinetic movement disorder. Additional neurological features included postnatal microcephaly and hypotonia. Five children died in childhood or adolescence (mean age of death: 9 years), mainly as a result of secondary respiratory complications. CACNA1B encodes the pore-forming subunit of the pre-synaptic neuronal voltage-gated calcium channel Cav2.2/N-type, crucial for SNARE-mediated neurotransmission, particularly in the early postnatal period. Bi-allelic loss-of-function variants in CACNA1B are predicted to cause disruption of Ca2+ influx, leading to impaired synaptic neurotransmission. The resultant effect on neuronal function is likely to be important in the development of involuntary movements and epilepsy. Overall, our findings provide further evidence for the key role of Cav2.2 in normal human neurodevelopment.MAK is funded by an NIHR Research Professorship and receives funding from the Wellcome Trust, Great Ormond Street Children's Hospital Charity, and Rosetrees Trust. E.M. received funding from the Rosetrees Trust (CD-A53) and Great Ormond Street Hospital Children's Charity. K.G. received funding from Temple Street Foundation. A.M. is funded by Great Ormond Street Hospital, the National Institute for Health Research (NIHR), and Biomedical Research Centre. F.L.R. and D.G. are funded by Cambridge Biomedical Research Centre. K.C. and A.S.J. are funded by NIHR Bioresource for Rare Diseases. The DDD Study presents independent research commissioned by the Health Innovation Challenge Fund (grant number HICF-1009-003), a parallel funding partnership between the Wellcome Trust and the Department of Health, and the Wellcome Trust Sanger Institute (grant number WT098051). We acknowledge support from the UK Department of Health via the NIHR comprehensive Biomedical Research Centre award to Guy's and St. Thomas' National Health Service (NHS) Foundation Trust in partnership with King's College London. This research was also supported by the NIHR Great Ormond Street Hospital Biomedical Research Centre. J.H.C. is in receipt of an NIHR Senior Investigator Award. The research team acknowledges the support of the NIHR through the Comprehensive Clinical Research Network. The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR, Department of Health, or Wellcome Trust. E.R.M. acknowledges support from NIHR Cambridge Biomedical Research Centre, an NIHR Senior Investigator Award, and the University of Cambridge has received salary support in respect of E.R.M. from the NHS in the East of England through the Clinical Academic Reserve. I.E.S. is supported by the National Health and Medical Research Council of Australia (Program Grant and Practitioner Fellowship)