127 research outputs found
Education and Entrepreneurship: Best Learning from Helm Project at Cenderawasih University
In 2013, as part of the Higher Education Leadership and Management national initiative sponsored by US AID, Universitas Cenderawasih proposed an action research project to address the under-employment of UNCEN graduates through purposeful entrepreneurship education. Although entrepreneurship education had been introduced previously at UNCEN, it had never been custom designed to integrate theory and practice appropriate to Papua as part of the formal curriculum. This paper focuses on the use of core principles of the action research process (ARP) to develop and implement a locally effective curriculum for students enrolled in UNCEN’s Faculty of Economics. A central value underlying the project was the development of a curriculum that could address social inequalities in Papua, specifically the significant under-representation of Papuan native peoples in the entrepreneurship sector.Through a mixed methods approach that used demographic, attitudinal and outcome data as well as observational, interview and focus group data, the ARP team designed an experientially-based learning module, documented implementation of thepilot learning module, evaluated its effectiveness, and developed proposals for improvement and institutionalization. As a result of its action research project, the ARP team suggests that future iterations of the entrepreneurship curriculum at UNCEN should adopt a culturally responsive pedagogy (Gay, 2010; Ladson-Billings, 1995) that addresses the disparities in cultural and social capital shown to be significant in the ARP to entrepreneurship education
Simultaneous evaluation of myocardial function, viability, and microvascular dysfunction by a new magnetic resonance technique
LSST: from Science Drivers to Reference Design and Anticipated Data Products
(Abridged) We describe here the most ambitious survey currently planned in
the optical, the Large Synoptic Survey Telescope (LSST). A vast array of
science will be enabled by a single wide-deep-fast sky survey, and LSST will
have unique survey capability in the faint time domain. The LSST design is
driven by four main science themes: probing dark energy and dark matter, taking
an inventory of the Solar System, exploring the transient optical sky, and
mapping the Milky Way. LSST will be a wide-field ground-based system sited at
Cerro Pach\'{o}n in northern Chile. The telescope will have an 8.4 m (6.5 m
effective) primary mirror, a 9.6 deg field of view, and a 3.2 Gigapixel
camera. The standard observing sequence will consist of pairs of 15-second
exposures in a given field, with two such visits in each pointing in a given
night. With these repeats, the LSST system is capable of imaging about 10,000
square degrees of sky in a single filter in three nights. The typical 5
point-source depth in a single visit in will be (AB). The
project is in the construction phase and will begin regular survey operations
by 2022. The survey area will be contained within 30,000 deg with
, and will be imaged multiple times in six bands, ,
covering the wavelength range 320--1050 nm. About 90\% of the observing time
will be devoted to a deep-wide-fast survey mode which will uniformly observe a
18,000 deg region about 800 times (summed over all six bands) during the
anticipated 10 years of operations, and yield a coadded map to . The
remaining 10\% of the observing time will be allocated to projects such as a
Very Deep and Fast time domain survey. The goal is to make LSST data products,
including a relational database of about 32 trillion observations of 40 billion
objects, available to the public and scientists around the world.Comment: 57 pages, 32 color figures, version with high-resolution figures
available from https://www.lsst.org/overvie
Aging Alters Functionally Human Dermal Papillary Fibroblasts but Not Reticular Fibroblasts: A New View of Skin Morphogenesis and Aging
Understanding the contribution of the dermis in skin aging is a key question, since this tissue is particularly important for skin integrity, and because its properties can affect the epidermis. Characteristics of matched pairs of dermal papillary and reticular fibroblasts (Fp and Fr) were investigated throughout aging, comparing morphology, secretion of cytokines, MMPs/TIMPs, growth potential, and interaction with epidermal keratinocytes. We observed that Fp populations were characterized by a higher proportion of small cells with low granularity and a higher growth potential than Fr populations. However, these differences became less marked with increasing age of donors. Aging was also associated with changes in the secretion activity of both Fp and Fr. Using a reconstructed skin model, we evidenced that Fp and Fr cells do not possess equivalent capacities to sustain keratinopoiesis. Comparing Fp and Fr from young donors, we noticed that dermal equivalents containing Fp were more potent to promote epidermal morphogenesis than those containing Fr. These data emphasize the complexity of dermal fibroblast biology and document the specific functional properties of Fp and Fr. Our results suggest a new model of skin aging in which marked alterations of Fp may affect the histological characteristics of skin
Copy Number Variation of KIR Genes Influences HIV-1 Control
The authors that the number of activating and inhibitory KIR genes varies between individuals and plays a role in the regulation of immune mechanisms that determine HIV-1 control
Impact of large-scale distribution and subsequent use of free nicotine patches on primary care physician interaction
Decision making under time pressure: An independent test of sequential sampling models
Association of Type 1 Diabetes vs Type 2 Diabetes Diagnosed During Childhood and Adolescence With Complications During Teenage Years and Young Adulthood
The burden and determinants of complications and comorbidities in contemporary youth-onset diabetes are unknown
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