17 research outputs found
Antihyperglycemic effect of casearia sylvestris leaves extract in streptozotocin induced diabetic rats
The antihyperglycaemic effect of Casearia sylvestris aqueous extract (CS) and its flavonoidic fraction using in vivo models in streptozotocin-induced diabetic rats was evaluated. CS (500 mg/kg) reduced blood glucose in rats three weeks after a single oral dose. The blood glucose significantly decreased in a test of tolerance to insulin. Phytochemical investigation on TLC, HPLC-DAD and NMR spectral analysis of extract and fractions confirmed the presence of flavonoids. These results direct the hypothesis that CS improves glucose metabolism by reducing insulin resistance, and it may be useful for the treatment of type 2 diabetes.Colegio de Farmacéuticos de la Provincia de Buenos Aire
Antihyperglycemic effect of casearia sylvestris leaves extract in streptozotocin induced diabetic rats
The antihyperglycaemic effect of Casearia sylvestris aqueous extract (CS) and its flavonoidic fraction using in vivo models in streptozotocin-induced diabetic rats was evaluated. CS (500 mg/kg) reduced blood glucose in rats three weeks after a single oral dose. The blood glucose significantly decreased in a test of tolerance to insulin. Phytochemical investigation on TLC, HPLC-DAD and NMR spectral analysis of extract and fractions confirmed the presence of flavonoids. These results direct the hypothesis that CS improves glucose metabolism by reducing insulin resistance, and it may be useful for the treatment of type 2 diabetes.Colegio de Farmacéuticos de la Provincia de Buenos Aire
Synthesis, characterization, and photocatalytic activity of pure and N-, B-, or Ag- Doped TiO2
This article reports the synthesis and characterization of pure and N-, B-, and Ag-doped TiO2 and the ability of these oxides to photodegrade methylene blue (MB) under sunlight or UV-ABC radiation. The compounds were synthesized using the sol-gel method and characterized by scanning electron microscopy, X-ray diffraction, diffuse reflectance spectroscopy, Fourier transform infrared spectroscopy, thermogravimetric analysis, and X-ray photoelectron spectroscopy. Photocatalytic efficiency was significantly increased by N-doping, resulting in 98% MB decomposition under UV-ABC irradiation for 180 min. Ag- and B-doped TiO2 lowered MB degradation rates to 52 and 73%, respectively, compared with pure TiO2. The same behavior was observed with exposure to UV-Vis, with 88, 65, 60, and 42% MB removal with N-doped, pure, B-doped, and Ag-doped TiO2, respectively. Under visible light alone, N-doped TiO2 exhibited higher photocatalytic efficiency than commercial P25-type TiO2. Photocatalysis with N-doped TiO2 proved to be a promising alternative for MB degradation, given the potential of employing solar energy, thus minimizing operating costs
Antihyperglycemic effect of casearia sylvestris leaves extract in streptozotocin induced diabetic rats
The antihyperglycaemic effect of Casearia sylvestris aqueous extract (CS) and its flavonoidic fraction using in vivo models in streptozotocin-induced diabetic rats was evaluated. CS (500 mg/kg) reduced blood glucose in rats three weeks after a single oral dose. The blood glucose significantly decreased in a test of tolerance to insulin. Phytochemical investigation on TLC, HPLC-DAD and NMR spectral analysis of extract and fractions confirmed the presence of flavonoids. These results direct the hypothesis that CS improves glucose metabolism by reducing insulin resistance, and it may be useful for the treatment of type 2 diabetes.Colegio de Farmacéuticos de la Provincia de Buenos Aire
Pervasive gaps in Amazonian ecological research
Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4
While the increasing availability of global databases on ecological communities has advanced our knowledge
of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In
the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of
Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus
crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced
environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian
Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by
2050. This means that unless we take immediate action, we will not be able to establish their current status,
much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio
Pervasive gaps in Amazonian ecological research
Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5,6,7 vast areas of the tropics remain understudied.8,9,10,11 In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepresented in biodiversity databases.13,14,15 To worsen this situation, human-induced modifications16,17 may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%–18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost
Caracterização e comportamento higroscópico do pó da polpa de cajá liofilizada
A higroscopicidade de um alimento desidratado está ligada Ă sua estabilidade fĂsica, quĂmica e microbiolĂłgica. Este trabalho teve como objetivos a caracterização fĂsico-quĂmica e o comportamento higroscĂłpico dos pĂłs da polpa de cajá liofilizada contendo maltodextrina (DE20). Foram feitas as análises de umidade, pH, sĂłlidos solĂşveis, acidez total titulável, ácido ascĂłrbico, açúcares, cor, higroscopicidade e o grau de caking. Para obtenção das isotermas os modelos de BET, GAB, Henderson e Oswin na temperatura de 25 ÂşC foram ajustados e avaliados. A adição de maltodextrina Ă polpa de cajá resultou em um pĂł com menor higroscopicidade e grau de caking. AlĂ©m disto, os resultados demonstraram que a adição da maltodextrina confere um pĂł estatisticamente diferente (p < 0,05) do pĂł sem adição de maltodextrina com relação ao teor de umidade, sĂłlidos solĂşveis, acidez total titulável, ácido ascĂłrbico, açúcares e cor. As isotermas dos pĂłs apresentaram comportamento do tipo III, caracterĂstico de materiais ricos em carboidratos. Os resultados mostraram que os melhores ajustes para as isotermas foram os modelos de BET e Henderson para o pĂł da polpa de cajá integral e o pĂł adicionado de maltodextrina, respectivamente