CFD Modelling of the Condensation Inside a Supersonic Ejector Working with R134a

Abstract The present work is about CFD modelling of condensing flow inside a supersonic ejector. The geometry used for the simulations reproduces a small-scale prototype ejector chiller built at Georgia Institute of Technology (Atlanta). The working fluid is R134a, whose expansion inside the primary nozzle and mixing chamber can lead to non-equilibrium condensation phenomena. These alter the pressure and Mach profiles along the ejector, thus generating severe thermodynamic losses. The numerical analysis of non-equilibrium condensation requires modelling of the microscopic behaviour of the fluid with a high level of fidelity. In this study, the condensation of R134a is simulated by means of two in-house developed numerical models. The first considers equilibrium conditions between the phases whereas the latter reproduces the non-equilibrium behaviour of the phase transition. Comparisons are made to understand the limitations and advantages of both approaches

CFD Modeling of the Supersonic Condensation Inside a Steam Ejector

Abstract Supersonic steam ejectors are commonly used in many applications, for example suction of non-condensable gases in steam power plants or heat-powered chillers. In the specific case of ejector chillers, CFD studies of the ejector are necessary for optimization of this device because ejector performances have a direct impact on the COP of the chiller. The complex ejector flow and the high Mach numbers make characterization of the phase change inside this component difficult. Metastability effects also have to be accounted for and some CFD commercial software provide built-in wet-steam models for this purpose. A simpler approach for numerical modeling of multiphase ejector is the Homogeneous Equilibrium Model (HEM) in which the phase change occurs in equilibrium conditions, i.e. metastability is neglected. These second kinds of models are still important tools for preliminary analysis of condensing ejectors. In the present paper a comparison between commercial software wet-steam models and an in-house developed model based on HEM is presented

P Systems with Endosomes

P Systems are computing devices inspired by the structure and the func- tioning of a living cell. A P System consists of a hierarchy of membranes, each of them containing a multiset of objects, a set of evolution rules, and possibly other membranes. Evolution rules are applied to the objects of the same membrane with maximal parallelism. In this paper we present an extension of P Systems, called P Systems with Endosomes (PE Systems), in which endosomes can be explicitly modeled. We show that PE Systems are universal even if only the simplest form of evolution rules is considered, and we give one application examples

On the Interpretation of Delays in Delay Stochastic Simulation of Biological Systems

Delays in biological systems may be used to model events for which the underlying dynamics cannot be precisely observed. Mathematical modeling of biological systems with delays is usually based on Delay Differential Equations (DDEs), a kind of differential equations in which the derivative of the unknown function at a certain time is given in terms of the values of the function at previous times. In the literature, delay stochastic simulation algorithms have been proposed. These algorithms follow a "delay as duration" approach, namely they are based on an interpretation of a delay as the elapsing time between the start and the termination of a chemical reaction. This interpretation is not suitable for some classes of biological systems in which species involved in a delayed interaction can be involved at the same time in other interactions. We show on a DDE model of tumor growth that the delay as duration approach for stochastic simulation is not precise, and we propose a simulation algorithm based on a ``purely delayed'' interpretation of delays which provides better results on the considered model

Aspects of multiscale modelling in a process algebra for biological systems

We propose a variant of the CCS process algebra with new features aiming at allowing multiscale modelling of biological systems. In the usual semantics of process algebras for modelling biological systems actions are instantaneous. When different scale levels of biological systems are considered in a single model, one should take into account that actions at a level may take much more time than actions at a lower level. Moreover, it might happen that while a component is involved in one long lasting high level action, it is involved also in several faster lower level actions. Hence, we propose a process algebra with operations and with a semantics aimed at dealing with these aspects of multiscale modelling. We study behavioural equivalences for such an algebra and give some examples

Tumorigenic Potential of Olfactory Bulb-Derived Human Adult Neural Stem Cells Associates with Activation of TERT and NOTCH1

BACKGROUND: Multipotent neural stem cells (NSCs) have been isolated from neurogenic regions of the adult brain. Reportedly, these cells can be expanded in vitro under prolonged mitogen stimulation without propensity to transform. However, the constitutive activation of the cellular machinery required to bypass apoptosis and senescence places these cells at risk for malignant transformation. METHODOLOGY/PRINCIPAL FINDINGS: Using serum-free medium supplemented with epidermal growth factor (EGF) and basic fibroblast growth factor (bFGF), we established clonally derived NS/progenitor cell (NS/PC) cultures from the olfactory bulb (OB) of five adult patients. The NS/PC cultures obtained from one OB specimen lost growth factor dependence and neuronal differentiation at early passage. These cells developed glioblastoma tumors upon xenografting in immunosuppressed mice. The remaining NS/PC cultures were propagated either as floating neurospheres or as adherent monolayers with maintenance of growth factor dependence and multipotentiality at late passage. These cells were engrafted onto the CNS of immunosuppressed rodents. Overall, the grafted NS/PCs homed in the host parenchyma showing ramified morphology and neuronal marker expression. However, a group of animals transplanted with NS/PCs obtained from an adherent culture developed fast growing tumors histologically resembling neuroesthesioblastoma. Cytogenetic and molecular analyses showed that the NS/PC undergo chromosomal changes with repeated in vitro passages under mitogen stimulation, and that up-regulation of hTERT and NOTCH1 associates with in vivo tumorigenicity. CONCLUSIONS/SIGNIFICANCE: Using culturing techniques described in current literature, NS/PCs arise from the OB of adult patients which in vivo either integrate in the CNS parenchyma showing neuron-like features or initiate tumor formation. Extensive xenografting studies on each human derived NS cell line appear mandatory before any use of these cells in the clinical setting

Définition de la tension standard non isotherme

The authors propose a definition of the non-isothermic standard electric tension. The temperature coefficient of this tension is equal to that of the absolute electric tension of the electrode, and is thus connected with the electrode reaction of the metal concerned, independently of the reaction occurring at the other electrode of the tensiometric cell. The adoption of this non-isothermic tension makes it possible to draw up simple tables. The authors discuss the possibilities of determining it experimentally. © 1961.SCOPUS: ar.jinfo:eu-repo/semantics/publishe

N° 117. — Spectres de para-, méta- et ortho-terphényle dans l’ultraviolet lointain

On a étudié les spectres d’absorption dans l’ultraviolet lointain jusqu’à 1 700 Å des trois terphényle méta-, para- et ortho-, à l’état solide en couche mince polycrystalline à la température de l’air liquide. Un appareillage et une technique spéciales ont été développées pour l’obtention des spectres qui montrent pour le p-terphényle seulement deux bandes d’absorption très larges et très mal définies à 1 900 et 1 700-1 750 Å environ et pour les deux autres terphényles une absorption pratiquement continue dans le même domaine, probablement due à la superposition non résolue de deux transitions électroniques comme pour le p-terphényle. L’absence totale de structure de vibration et la séparation énergétique entre les deux bandes indiquent que les spectres observés doivent être attribués à deux excitations électroniques différentes, immédiatement suivies par la dissociation des molécules excitées avec production de fragments se trouvant eux-mêmes dans un état électronique excité