A la juventud hispana de Unamuno: A Key Project in the Creative Process of Del sentimiento trágico de la vida

Este trabajo examina uno de los textos más significativos dentro del proceso creativo que condujo a Del sentimiento trágico de la vida: A la juventud hispana, un ensayo sobre el erostratismo y otros temas que, filtrado a través del Tratado del amor de Dios, desemboca finalmente en la obra filosófica más representativa de Unamuno. Aporta además nuevos datos sobre la filiación de los manuscritos que forman parte del antetexto de Del sentimiento trágico de la vida.This work analyses one of the most relevant texts in the creative process that brought to Del sentimiento trágico de la vida: A la juventud hispana, an essay about the herostratism and other themes that, re-elaborated in the Tratado del amor de Dios, resulted in the most important philosophical book by Unamuno. It also provides new data about the filiation of the various manuscripts that compose the avantext of Del sentimiento trágico de la vida

Le Noches de Placer di Alonso de Castillo Solorzano. Edizione critica e studio

El trabajo que presento es la edición crítica de las Noches de placer, colección de novelas cortas de Alonso de Castillo Solórzano, publicada en Barcelona en 1631 en la tipografía de Sebastián de Cormellas. La introducción al texto crítico brinda un estado de la cuestión que se centra en la vida y la producción narrativa de Castillo Solórzano. Estudio el importante papel de los paratextos (introducción, prólogo, etc.) en la estructura global de la obra. La parte introductoria se centra además en las fuentes italianas y españolas utilizadas por el autor, analizando la estrecha relación con el teatro contemporáneo –que «resucita» en la misma estructura de la colección– y las técnicas de reescritura de los relatos de los novellieri: gracias a la aplicación de estrategias “moralizantes”, el autor puede tratar temas escabrosos que se consideraban inadecuados (a veces hasta prohibidos) en la literatura española post-conciliar. Se examinan también dos de los personajes recurrentes en la producción solorzaniana, es decir, el cautivo y el figurón-celoso, y se proporciona un detallado resumen de cada cuento de la colección. El texto de las doce novelas se ha fijado siguiendo criterios editoriales rigurosos y se ha anotado convenientemente: las notas al texto ofrecen aclaraciones lexicales y gramaticales, especifican las alusiones literarias, históricas y mitológicas y dan razón de los loci critici más relevantes

Le Noches de Placer di Alonso de Castillo Solórzano. Edizione critica e studio

The study I present is the critical edition of Noches de placer, a collection of novelas cortas by Alonso de Castillo Solórzano, published in Barcelona in 1631 by the typographer Sebastián Cormellas. The introduction reconstructs the status quaestionis about Castillo Solórzano’s life ad narrative production, it studies the role of the preliminary texts (introduction, prologue, etc) and, in particular, analyses their structural function along the book. It also focuses on the Italian and Spanish sources used by the author, and on the connections with the dramatic literature of the period (which are clearly reflected in the same structure of the book). Furthermore, it investigates the techniques of re-writing of the Italian novelle: through the application of moralizing strategies, the writer is able to face thorny topics which were considered inadequate (sometimes even forbidden) in the Counter- Reformation Spain. Two of the most recurrent characters in Castillo Solórzano’s production are examined: the cautivo and the figurón-celoso. The introduction provides also a thorough synopsis of each short novel. The text of the novel has been fixed through meticulous philological rules and it has been annotated: the notes give lexical and grammatical explanations, points out the literary, historical and mythological references and explain the editorial choices

El «Lisardo enamorado» de Alonso de Castillo Solórzano: dobles redacciones, problemas textuales y cuestiones lingüísticas

The following article aims to analyse the editorial history of Lisardo enamorado by Alonso de Castillo Solórzano (Valencia, 1629) and of its first version, Escarmientos de amor moralizados (Seville, 1628), studying the discrepant linguistic and idiological elements and identifying the re-elaboration techniques used by its autor.El presente trabajo se propone estudiar las vicisitudes editoriales del Lisardo enamorado de Alonso de Castillo Solórzano (Valencia, 1629) y de su primera versión, los Escarmientos de amor moralizados (Sevilla, 1628), pasando revista a los elementos lingüísticos e ideológicos que los distinguen e identificando las modalidades de reelaboración empleadas por su autor

Traumatic buccal fat pad herniation in an infant

Traumatic herniation of buccal fat pad (BFP) is very rare, usually seen in young children, from 5 months to 12 years of age. A minor injury or perforation of the buccinator muscle and buccal mucosa can cause the extrusion of the buccal fat pad into the oral cavity. A differential diagnosis is very important but a history of trauma, an absence of masses before the accident, anatomical site and fatty appearance should suggest the correct diagnosis. The treatment options are usually excision or repositioning of the herniated fat. For the present case report, a 7 month-old boy, diagnosed with traumatic buccal fat pad herniation, was successfully treated with surgical excision

Pharmacokinetics and antinociceptive effects of tramadol and its metabolite O-desmethyltramadol following intravenous administration in sheep

Although sheep are widely used as an experimental model for various surgical procedures there is a paucity of data on the pharmacokinetics and efficacy of analgesic drugs in this species. The aims of this study were to investigate the pharmacokinetics of intravenously (IV) administered tramadol and its active metabolite O-desmethyltramadol (M1) and to assess the mechanical antinociceptive effects in sheep. In a prospective, randomized, blinded study, six healthy adult sheep were given 4 and 6\u2009mg/kg tramadol and saline IV in a cross-over design with a 2-week wash-out period. At predetermined time points blood samples were collected and physiological parameters and mechanical nociceptive threshold (MNT) values were recorded. The analytical determination of tramadol and M1 was performed using high performance liquid chromatography. Pharmacokinetic parameters fitted a two- and a non-compartmental model for tramadol and M1, respectively. Normally distributed data were analysed by a repeated mixed linear model. Plasma concentration vs. time profiles of tramadol and M1 were similar after the two doses. Tramadol and M1 plasma levels decreased rapidly in the systemic circulation, with both undetectable after 6\u2009h following drug administration. Physiological parameters did not differ between groups; MNT values were not statistically significant between groups at any time point. It was concluded that although tramadol and M1 concentrations in plasma were above the human minimum analgesic concentration after both treatments, no mechanical antinociceptive effects of tramadol were reported. Further studies are warranted to assess the analgesic efficacy of tramadol in sheep

Big Data e Assicurazioni. Regolamentazione dei Mercati e Tutela Giuridica

In questo contributo presenteremo un'analisi sul tema del trattamento dei dati personali in ambito assicurativo. In particolare, nell'articolo verranno analizzati i risvolti giuridici dell'utilizzo dei Big Data e il loro impiego per la risoluzione di asimmetrie informative, da qualificare come inefficienze di mercato

Quality traits of saffron produced in Italy: geographical area effect and good practices

Saffron (Crocus sativus L.) is the most expensive spice in the world and is used in food, cosmetic and dyeing industries. Considering that the production of saffron is increasingly widespread in medium-small Italian farms as well as the scarceness of information and studies regarding the quality of the saffron produced in Italy, the principal aim of this study was to investigate the quality of Italian saffron. Qualitative analysis was conducted in accordance with ISO 3632 1,2:2010-2011 considering 484 samples collected over four years (2015-2018). In particular, moisture content, aroma strength (safranal), colouring strength (crocin) and flavour strength (picrocrocin) were assessed for each sample, and whether spice quality varied according to the geographical area where the spice was produced was also investigated. Qualitative analysis showed that the majority (84-93%) of the samples analysed are of the first quality category, regardless of the year of production. Moisture content and colouring strength are the factors that influence the quality of the spice most. Principal component analysis showed that quality is not influenced by the geographical area where the spice was produced. Finally, some best agricultural practices to obtain a high quality saffron spice are reported

Techno-Economic Optimisation for a Wave Energy Converter via Genetic Algorithm

Although sea and ocean waves have been widely acknowledged to have the potential of providing sustainable and renewable energy, the emergence of a self-sufficient and mature industry is still lacking. An essential condition for reaching economic viability is to minimise the cost of electricity, as opposed to simply maximising the converted energy at the early design stages. One of the tools empowering developers to follow such a virtuous design pathway is the techno-economic optimisation. The purpose of this paper is to perform a holistic optimisation of the PeWEC (pendulum wave energy converter), which is a pitching platform converting energy from the oscillation of a pendulum contained in a sealed hull. Optimised parameters comprise shape; dimensions; mass properties and ballast; power take-off control torque and constraints; number and characteristics of the pendulum; and other subcomponents. Cost functions are included and the objective function is the ratio between the delivered power and the capital expenditure. Due to its ability to effectively deal with a large multi-dimensional design space, a genetic algorithm is implemented, with a specific modification to handle unfeasible design candidate and improve convergence. Results show that the device minimising the cost of energy and the one maximising the capture width ratio are substantially different, so the economically-oriented metric should be preferred