145 research outputs found
Women's experiences of the policing of domestic violence : a thesis presented in partial fulfillment of the requirements for the degree of Masters of Arts in Psychology at Massey University
Domestic Violence is a pervasive crime. It weaves itself into the network of our society. In Aotearoa/New Zealand the Government has introduced legislation designed to reduce and prevent violence in the home and has seen an increase in reported domestic violence since its introduction. Despite some evidence to the contrary, when all types of violence are taken into account the majority of victims are women and children. Domestic violence can be best understood in terms of power and control in relationships, and gender relations in our society, and our socio-cultural-historical context. Given our current legislative context, policing is a critical dimension of effective intervention to reduce and prevent domestic violence. This research explores women's experiences of the policing of domestic violence in a rural, South Island locality. Alongside professional and university ethics, feminist research principles guided the researcher's engagement with women participants in semi-structured interviews. A narrative approach to research was used as a framework to gather, analyze and write up the accounts of nine women's experiences of the policing of domestic violence. Through this narrative approach a co-creative, fluid and dynamic relationship between the researcher and participants produced hybrid accounts and new insights and understandings in relation to domestic violence and the policing of this crime. Findings are presented as themes related to three clearly identified phases in the women's stories of policing: making contact, police responses and their impact, referrals and follow up. The research suggests there are still substantial problems for women's safety in relation to effective policing of domestic violence in Aotearoa/New Zealand from the standpoints of these women
Conceptual Metaphors as Interpretive Tools in Qualitative Research: A Re-Examination of College Studentsâ Diversity Discussions
In this contribution to the growing literature on conceptual metaphor as a fruitful heuristic for qualitative analysis, the authors re-analyzed transcripts of college student discussions of problematic situations involving cultural diversity and interpersonal conflict. The authors show how they identified metaphorical linguistic expressions and from them derived three conceptual metaphors (life is a journey, the problem is a barrier/maze, and the self is divided) that in turn formed patterns or constellations of meanings in studentsâ problem-solving strategies. As an interpretive tool, conceptual metaphors link certain isolated individual metaphors to these larger patterns of meaning, including ideological frameworks readily available in US culture
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Adapting Urban Water Systems to Manage Scarcity in the 21st Century: The Case of Los Angeles.
Acute water shortages for large metropolitan regions are likely to become more frequent as climate changes impact historic precipitation levels and urban population grows. California and Los Angeles County have just experienced a severe four year drought followed by a year of high precipitation, and likely drought conditions again in Southern California. We show how the embedded preferences for distant sources, and their local manifestations, have created and/or exacerbated fluctuations in local water availability and suboptimal management. As a socio technical system, water management in the Los Angeles metropolitan region has created a kind of scarcity lock-in in years of low rainfall. We come to this through a decade of coupled research examining landscapes and water use, the development of the complex institutional water management infrastructure, hydrology and a systems network model. Such integrated research is a model for other regions to unpack and understand the actual water resources of a metropolitan region, how it is managed and potential ability to become more water self reliant if the institutions collaborate and manage the resource both parsimoniously, but also in an integrated and conjunctive manner. The Los Angeles County metropolitan region, we find, could transition to a nearly water self sufficient system
Is it beneficial to increase the provision of thrombolysis? - a discrete-event simulation model
Background: Although Thrombolysis has been
licensed in the UK since 2003, it is still administered
only to a small percentage of eligible patients.
Aim: We consider the impact of investing the impact
of thrombolysis on important acute stroke services,
and the effect on quality of life. The concept is illustrated using data from the Northern Ireland Stroke
Service.
Design: Retrospective study.
Methods: We first present results of survival analysis
utilizing length of stay (LOS) for discharge destinations, based on data from the Belfast City
Hospital (BCH). None of these patients actually
received thrombolysis but from those who would
have been eligible, we created two initial groups,
the first representing a scenario where they received
thrombolysis and the second comprising those who
do not receive thrombolysis. On the basis of the
survival analysis, we created several subgroups
based on discharge destination. We then developed
a discrete event simulation (DES) model, where each
group is a patient pathway within the simulation.
Coxian phase type distributions were used to
model the group LOS. Various scenarios were
explored focusing on cost-effectiveness across hospital, community and social services had thrombolysis been administered to these patients, and the
possible improvement in quality of life, should the
proportion of patients who are administered thrombolysis be increased. Our aim in simulating various
scenarios for this historical group of patients is to
assess what the cost-effectiveness of thrombolysis
would have been under different scenarios; from
this we can infer the likely cost-effectiveness of
future policies.
Results: The cost of thrombolysis is offset by
reduction in hospital, community rehabilitation
and institutional care costs, with a corresponding
improvement in quality of life.
Conclusion: Our model suggests that provision of
thrombolysis would produce moderate overall improvement to the service assuming current levels
of funding.peer-reviewe
Drp2 and Periaxin Form Cajal Bands with Dystroglycan But Have Distinct Roles in Schwann Cell Growth
Cajal bands are cytoplasmic channels flanked by appositions where the abaxonal surface of Schwann cell myelin apposes and adheres to the overlying plasma membrane. These appositions contain a dystroglycan complex that includes periaxin and dystrophin-related protein 2 (Drp2). Loss of periaxin disrupts appositions and Cajal bands in Schwann cells and causes a severe demyelinating neuropathy in mouse and man. Here we have investigated the role of mouse Drp2 in apposition assembly and Cajal band function and compared it to periaxin. We show that Periaxin and Drp2 are not only both required to form appositions, but they must also interact. Periaxin-Drp2 interaction is also required for Drp2 phosphorylation but phosphorylation is not required for the assembly of appositions. Drp2 loss causes corresponding increases in Dystrophin family members, utrophin and dystrophin Dp116 though dystroglycan remains unchanged. We also show that all dystroglycan complexes in Schwann cells utilise the uncleaved form of β-dystroglycan. Drp2-null Schwann cells have disrupted appositions and Cajal bands, and they undergoe focal hypermyelination and concomitant demyelination. Nevertheless, they do not have the short internodal lengths and associated reduced nerve conduction velocity seen in the absence of periaxin, showing that periaxin regulates Schwann cell elongation independent of its role in the dystroglycan complex. We conclude that the primary role of the dystroglycan complex in appositions is to stabilize and limit the radial growth of myelin
A Cross-Taxonomic Comparison of Insect Responses to Grassland Management and Land-Use Legacies
Many species of plants and animals associated with grasslands are rare or declining due to habitat loss and degradation. Although grassland plants and insects evolved in the context of both grazing and fire, the appropriate use of grazing and fire has been debated among those concerned with protecting insect communities. We established an experiment to test insect responses to three grassland management treatments: (1) patch-burn graze (burning of spatially distinct patches and free access by cattle), (2) grazeand- burn (burning of entire tract with free access by cattle), and (3) burn-only. Because we expected that land-use legacies could also affect insect abundance and diversity, we evaluated effects of time since fire, grazing history, remnant history (remnant or reconstructed grassland) and pre-treatment vegetation characteristics, which were assumed to be a legacy of prior land-use. Butterflies (Lepidoptera), ants (Hymenoptera: Formicidae), and leaf beetles (Coleoptera: Chrysomelidae) were surveyed for three years to compare their responses to each of these treatments as measured by abundance, richness and species diversity. Each of these taxa is relatively diverse and was expected to have the potential to have strong negative responses to grazing and burning, but we predicted more positive responses to patch-burn grazing. Our results showed that land-use legacies affected insect abundance, richness and diversity, but treatments did not. Ant abundance was lower in tracts with a history of heavy grazing. Ant species richness was positively associated with pre-treatment time since fire and vegetation height and negatively associated with pre-treatment proportion native plant cover. Butterfly abundance was positively associated with pre-treatment litter cover. Leaf beetle diversity was positively associated with pre-treatment native plant cover, and leaf beetle abundance was negatively associated with time since fire. Our results indicate that land-use legacies can exert more influence on grassland insect community composition than current management, but the particular aspects of these land-use legacies that are important vary across insect taxa. The implications of these finding are that (1) land-use legacies should garner more attention in grassland management and (2) conservation of grassland insect communities will be improved by taxonspecific analysis of land-use legacy variables
Report of the panel on the land surface: Process of change, section 5
The panel defined three main areas of study that are central to the Solid Earth Science (SES) program: climate interactions with the Earth's surface, tectonism as it affects the Earth's surface and climate, and human activities that modify the Earth's surface. Four foci of research are envisioned: process studies with an emphasis on modern processes in transitional areas; integrated studies with an emphasis on long term continental climate change; climate-tectonic interactions; and studies of human activities that modify the Earth's surface, with an emphasis on soil degradation. The panel concluded that there is a clear requirement for global coverage by high resolution stereoscopic images and a pressing need for global topographic data in support of studies of the land surface
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Writ(h)ing Images: Imagination, the Human Form, and the Divine in William Blake, Salman Rushdie, and Simon Louvish
In this paper, we address issues in segmentation Of remotely sensed LIDAR (LIght Detection And Ranging) data. The LIDAR data, which were captured by airborne laser scanner, contain 2.5 dimensional (2.5D) terrain surface height information, e.g. houses, vegetation, flat field, river, basin, etc. Our aim in this paper is to segment ground (flat field)from non-ground (houses and high vegetation) in hilly urban areas. By projecting the 2.5D data onto a surface, we obtain a texture map as a grey-level image. Based on the image, Gabor wavelet filters are applied to generate Gabor wavelet features. These features are then grouped into various windows. Among these windows, a combination of their first and second order of statistics is used as a measure to determine the surface properties. The test results have shown that ground areas can successfully be segmented from LIDAR data. Most buildings and high vegetation can be detected. In addition, Gabor wavelet transform can partially remove hill or slope effects in the original data by tuning Gabor parameters
Increasing Internodal Distance in Myelinated Nerves Accelerates Nerve Conduction to a Flat Maximum
SummaryPredictions that conduction velocities are sensitive to the distance between nodes of Ranvier in myelinated axons have implications for nervous system function during growth and repair [1â3]. Internodal lengths defined by Schwann cells in hindlimb nerves, for example, can undergo a 4-fold increase during mouse development, and regenerated nerves have internodes that are uniformly short [4, 5]. Nevertheless, the influence of internodal length on conduction speed has limited experimental support. Here, we examined this problem in mice expressing a mutant version of periaxin, a protein required for Schwann cell elongation [4]. Importantly, elongation of mutant Schwann cells was retarded without significant derangements to myelination or axon caliber. In young mice with short mutant Schwann cells, nerve conduction velocity was reduced and motor function was impaired. This demonstrates a functional relationship between internodal distance and conduction speed. Moreover, as internodes lengthened during postnatal growth, conduction velocities recovered to normal values and mutant mice exhibited normal motor and sensory behavior. This restoration of function confirms a further prediction by Huxley and Stämpfli that conduction speeds should increase as internodal distances lengthen until a âflat maximumâ is reached, beyond which no further gains in conduction velocity accrue [6]
Transcriptome analysis of pigeon milk production - role of cornification and triglyceride synthesis genes
BACKGROUND : The pigeon crop is specially adapted to produce milk that is fed to newly hatched young. The process of pigeon milk production begins when the germinal cell layer of the crop rapidly proliferates in response to prolactin, which results in a mass of epithelial cells that are sloughed from the crop and regurgitated to the young. We proposed that the evolution of pigeon milk built upon the ability of avian keratinocytes to accumulate intracellular neutral lipids during the cornification of the epidermis. However, this cornification process in the pigeon crop has not been characterised. RESULTS: We identified the epidermal differentiation complex in the draft pigeon genome scaffold and found that, like the chicken, it contained beta-keratin genes. These beta-keratin genes can be classified, based on sequence similarity, into several clusters including feather, scale and claw keratins. The cornified cells of the pigeon crop express several cornification-associated genes including cornulin, S100-A9 and A16-like, transglutaminase 6-like and the pigeon \u27lactating\u27 crop-specific annexin cp35. Beta-keratins play an important role in \u27lactating\u27 crop, with several claw and scale keratins up-regulated. Additionally, transglutaminase 5 and differential splice variants of transglutaminase 4 are up-regulated along with S100-A10. CONCLUSIONS: This study of global gene expression in the crop has expanded our knowledge of pigeon milk production, in particular, the mechanism of cornification and lipid production. It is a highly specialised process that utilises the normal keratinocyte cellular processes to produce a targeted nutrient solution for the young at a very high turnover
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