Fascitis necrotizante fulminante tras inyección intramuscular glútea

La fascitis necrotizante es una infección grave que afecta a la fascia y al tejido celular circundante, de diagnóstico complejo y que asocia una mortalidad elevada. Se han descrito múltiples factores de riesgo, siendo controvertida su asociación con la administración intramuscular de antiinflamatorios no esteroideos. Se presenta una serie de 3 casos clínicos documentados en nuestro departamento de fascitis necrotizante glútea tras inyección intramuscular, adjuntando una revisión de literatura.Necrotizing fasciitis is a serious infection that affects the fascia and the surrounding soft tissues, its diagnosis is complex and it associates with a high mortality. Despite being described many risk factors, the as - sociation with non-steroidal anti-inflammatory drugs remains controversial. We report a serie of 3 clinical cases of necrotizing fasciitis after muscle gluteal injection registered in our department. A medical literature review is presented as well

Strength design optimization of structural steel members according to Eurocode3

In order to design a steel member subjected to a bending moment and an axial load, there are an infinite number of possible solutions of I- or H‐steel cross-sections, the doubly-symmetric solution being just one of them. This paper presents a procedure to obtain the optimal steel cross-section from the infinite number of possible solutions. The process is based on the Reinforcement Sizing Diagrams employed in reinforced concrete strength design. The procedure looks for any type of solution regarding compact or non-compact steel sections. All aspects related to local instabilities are taken into account, as well as some special considerations in order to address the global instabilities associated with the slenderness of the steel element.The present work was financed by the Spanish Ministry of Education. The first author is a Spanish Government PhD fellow (FPU grant AP 2010‐3707)

Optimization of structural steel members with non-compact sections according to EC3

Para el diseño de un elemento estructural tipo viga-columna se suelen seleccionar secciones doblemente simétricas, generalemente secciones laminadas tipo H o I. Sin embargo, ésta es sólo una de las muchas soluciones posibles y, por lo general, no será la sección óptima. Hernández-Montes et al. 2004, y Hernández-Montes et al. 2005, proponen los diagramas RSD (Reinforcement Sizing Diagrams) como un método para obtener la solución óptima para el armado longitudinal de una sección de hormigón sometida a flexión uniaxial y a compresión. Esta metodología ha sido extendida para secciones de acero compactas según el Eurocódigo 3 (EC3) por Gil-Martín et al. 2008, y esta comunicación procederá de manera similar para buscar soluciones no compactas, esto es, soluciones en clases 3 ó 4 según EC3, considerando todos los aspectos relacionados con la aparición de inestabilidades locales. Además, se introducirán las consideraciones especiales para tener en cuenta las inestabilidades globales relacionadas con la esbeltez del miembro.In a designed structure, the chosen section for a member as a steel beam-column will be doubly-symmetric and it will correspond to one provided by a standard rolled steel section as H or I. However, this solution is just one of the big number of possible solutions and the optimal one may correspond to other section different from the symmetric one. Hernandez-Montes et al. 2004, and Hernández-Montes et al. 2005, proposed the Reinforcement Sizing Diagrams (RSD) as an approach for getting the optimal solution for the longitudinal reinforcing steel of a concrete section subjected to uniaxial bending and compression This methodology is extended for compact steel sections according to Eurocode 3 (EC3) by Gil-Martín et al. 2008 and this communication will proceed similarly for seeking non compact solutions, this is, sections corresponding to Class 3 or 4 according to EC3, considering all the aspects related with the appearance of local instabilities. Furthermore, special considerations are introduced to address the global instabilities associated with the slenderness of the steel element.TEP-19

Octahedron family: the double-expanded octahedron tensegrity

Es un preprintThe octahedron family of tensegrity structures is presented in this research. The octahedron and the expanded octahedron (well-known tensegrities in the literature) are the first and second components of the family. A new tensegrity is presented: the double-expanded octahedron. This new tensegrity form was obtained following the connectivity pattern of the octahedron family presented in this work. The values of the force densities or force:length ratios that satisfy the minimum required rank deficiency of the force density matrix were computed analytically. Two types of solutions are obtained: full and folded forms. Results show that each lower member of the octahedron family is a folded form of a superior member of this family. Several examples are shown.Grupo de Investigación TEP-19

Clinical Profile and Determinants of Mortality in Patients with Interstitial Lung Disease Admitted for COVID-19

COVID-19; Interstitial lung diseases; MortalityCOVID-19; Malalties pulmonars intersticials; MortalitatCOVID-19; Enfermedades pulmonares intersticiales; MortalidadBackground: Concern has risen about the effects of COVID-19 in interstitial lung disease (ILD) patients. The aim of our study was to determine clinical characteristics and prognostic factors of ILD patients admitted for COVID-19. Methods: Ancillary analysis of an international, multicenter COVID-19 registry (HOPE: Health Outcome Predictive Evaluation) was performed. The subgroup of ILD patients was selected and compared with the rest of the cohort. Results: A total of 114 patients with ILDs were evaluated. Mean ± SD age was 72.4 ± 13.6 years, and 65.8% were men. ILD patients were older, had more comorbidities, received more home oxygen therapy and more frequently had respiratory failure upon admission than non-ILD patients (all p < 0.05). In laboratory findings, ILD patients more frequently had elevated LDH, C-reactive protein, and D-dimer levels (all p < 0.05). A multivariate analysis showed that chronic kidney disease and respiratory insufficiency on admission were predictors of ventilatory support, and that older age, kidney disease and elevated LDH were predictors of death. Conclusions: Our data show that ILD patients admitted for COVID-19 are older, have more comorbidities, more frequently require ventilatory support and have higher mortality than those without ILDs. Older age, kidney disease and LDH were independent predictors of mortality in this population

Mindfulness-Based Program Plus Amygdala and Insula Retraining (MAIR) for the Treatment of Women with Fibromyalgia : a Pilot Randomized Controlled Trial

The lack of highly effective treatments for fibromyalgia (FM) represents a great challenge for public health. The objective of this parallel, pilot randomized controlled trial (RCT) was two-fold: (1) to analyze the clinical effects of mindfulness plus amygdala and insula retraining (MAIR) compared to a structurally equivalent active control group of relaxation therapy (RT) in the treatment of FM; and (2) to evaluate its impact on immune-inflammatory markers and brain-derived neurotrophic factor (BDNF)in serum. A total of 41 FM patients were randomized into two study arms: MAIR (intervention group)and RT (active control group), both as add-ons of treatment as usual. MAIR demonstrated significantly greater reductions in functional impairment, anxiety, and depression, as well as higher improvements in mindfulness, and self-compassion at post-treatment and follow-up, with moderate to large effectsizes. Significant decreases in pain catastrophizing and psychological inflexibility and improvementsin clinical severity and health-related quality of life were found at follow-up, but not at post-treatment,showing large effect sizes. The number needed to treat was three based on the criteria of ≥50% Fibromyalgia Impact Questionnaire (FIQ) reduction post-treatment. Compared to RT, the MAIRshowed significant decreases in BDNF. No effect of MAIR was observed in immune-inflammatorybiomarkers (i.e., TNF-α, IL-6, IL-10, and hs-CRP). In conclusion, these results suggest that MAIR, as an adjuvant of treatment-as-usual (TAU), appears to be effective for the management of FM symptomsand for reducing BDNF levels in serum

Reflection Seismic Imaging for Mineral Exploration in the Sotiel-Coronada Area, Southwest Spain

Near Surface Geoscience Conference & Exhibition Online 2020This work explores the first results of the seismic data acquired in the Sotiel-Coronada mine as part of the SIT4ME (Seismic Imaging Techniques for Mineral Exploration) project. In this experiment, a multi-source seismic data-set was acquired at the end of 2018 in the Sotiel- Coronada area of the Iberian Pyrite Belt (IPB) (southwest Spain). In the seismic experiment presented, 653 seismic receivers were deployed distributed in a pseudo 3D grid and six crooked lines across the study area. The sensors recorded c. 900 vibration points produced by a 32 Tn vibrotruck. Here, we present the stack results of the 2D seismic sections. Data from over 100 wells have been incorporating to aid in the structural interpretation. The preliminary interpretation reveals the complexity of this highly faulted ore-bearing area. Correlations between well log data information and 2D seismic profiles, suggest the location of a potentially mineralized area. The SIT4ME project has been funded by EIT Raw Materials (17024)

Symmetry preserving in Topological Mapping for tension structures

When using Topological Mapping (TM) together with the Force Density Method (FDM) in order to find a first form of equilibrium for a tension structure whose fixed nodes coincide in plan view with the vertices of a regular polygon, it has been observed that the symmetry may be lost. The problem is related to the mapping procedure that is introduced in the process. However, if some rules are followed in constructing the topology for the mesh, the symmetry can be preserved. With a symmetric mesh, the later cutting pattern generation process becomes simpler, easier, and cheaper. This paper will provide one simple algorithm that has been proved to work effectively in preserving the symmetry in the cited type of tension structures. Several examples are presented in order to better illustrate the applicability of these easy prescriptions.Grupo TEP 190This research work was carried out under the financial support provided by Spanish Ministry of Education and Science as part of the Research Projects BIA 2007-62595. The first author is a Spanish Government PhD fellow (FPU Grant AP 2010-3707)

Establecimiento de las bases biotecnológicas y ecológicas en la mejora genética de Vanilla planifolia Jacqs. (Orchidaceae)

Vanilla planifolia Jacks is a genetic resource of socio-economic importance to the State of Veracruz, México. However, in recent years, this culture is facing a serious problem due to the fall of its fruits. To contribute to the conservation, improvement and management of V. planifolia, it has been developed a network project for the strengthening of academic bodies sponsored by the Secretariat of public education. This paper presents some of the progress made in this context

Initiation and Single Dispensing in Cardiovascular and Insulin Medications: Prevalence and Explanatory Factors

: Background: Adherence problems have negative effects on health, but there is little information on the magnitude of non-initiation and single dispensing. Objective: The aim of this study was to estimate the prevalence of non-initiation and single dispensation and identify associated predictive factors for the main treatments prescribed in Primary Care (PC) for cardiovascular disease (CVD) and diabetes. Methods: Cohort study with real-world data. Patients who received a first prescription (2013-2014) for insulins, platelet aggregation inhibitors, angiotensin-converting enzyme inhibitors (ACEI) or statins in Catalan PC were included. The prevalence of non-initiation and single dispensation was calculated. Factors that explained these behaviours were explored. Results: At three months, between 5.7% (ACEI) and 9.1% (antiplatelets) of patients did not initiate their treatment and between 10.6% (statins) and 18.4% (ACEI) filled a single prescription. Body mass index, previous CVD, place of origin and having a substitute prescriber, among others, influenced the risk of non-initiation and single dispensation. Conclusions: The prevalence of non-initiation and single dispensation of CVD medications and insulin prescribed in PC in is high. Patient and health-system factors, such as place of origin and type of prescriber, should be taken into consideration when prescribing new medications for CVD and diabetes