74 research outputs found
Ridge Formation and De-Spinning of Iapetus via an Impact-Generated Satellite
We present a scenario for building the equatorial ridge and de-spinning
Iapetus through an impact-generated disk and satellite. This impact puts debris
into orbit, forming a ring inside the Roche limit and a satellite outside. This
satellite rapidly pushes the ring material down to the surface of Iapetus, and
then itself tidally evolves outward, thereby helping to de-spin Iapetus. This
scenario can de-spin Iapetus an order of magnitude faster than when tides due
to Saturn act alone, almost independently of its interior geophysical
evolution. Eventually, the satellite is stripped from its orbit by Saturn. The
range of satellite and impactor masses required is compatible with the
estimated impact history of Iapetus.Comment: 19 pages, 3 figures; Icarus, in pres
Impacto da degradação sobre o estoque total de carbono de florestas ripárias na Amazônia Oriental, Brasil
Effets d'un je�ne de courte dur�e sur les principaux constituants biochimiques de l'oursin Arbacia lixula. I. Stade de repos sexuel
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The identity of proteins associated with a small heat shock protein during heat stress in vivo indicates these chaperones protect a wide range of cellular functions.
The small heat shock proteins (sHSPs) are a ubiquitous class of ATP-independent chaperones believed to prevent irreversible protein aggregation and to facilitate subsequent protein renaturation in cooperation with ATP-dependent chaperones. Although sHSP chaperone activity has been studied extensively in vitro, understanding the mechanism of sHSP function requires identification of proteins that are sHSP substrates in vivo. We have used both immunoprecipitation and affinity chromatography to recover 42 proteins that specifically interact with Synechocystis Hsp16.6 in vivo during heat treatment. These proteins can all be released from Hsp16.6 by the ATP-dependent activity of DnaK and co-chaperones and are heat-labile. Thirteen of the putative substrate proteins were identified by mass spectrometry and reveal the potential for sHSPs to protect cellular functions as diverse as transcription, translation, cell signaling, and secondary metabolism. One of the putative substrates, serine esterase, was purified and tested directly for interaction with purified Hsp16.6. Hsp16.6 effectively formed soluble complexes with serine esterase in a heat-dependent fashion, thereby preventing formation of insoluble serine esterase aggregates. These data offer critical insights into the characteristics of native sHSP substrates and extend and provide in vivo support for the chaperone model of sHSP function
Bromophycolides C-I from the Fijian red alga Callophycus serratu
Bromophycolides C-I (1-7) were isolated from extracts of the Fijian red alga Callophycus serratus and identified by NMR and mass spectral techniques. These novel natural products share a carbon skeleton and biosynthetic origin with previously identified bromophycolides A (8) and B (9), which form a rare group of diterpene-benzoate macrolides. Bromophycolides C-I (1-7) displayed modest antineoplastic activity against a range of human tumor cell lines
Seasonal changes in body component indices and chemical composition in the pismo clam Tivela stultorum
Biochemical changes during reproduction and starvation in the sipunculid worm Phascolosoma agassizii
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