183 research outputs found
Affective Polarization in Multiparty Systems? Comparing Affective Polarization Towards Voters and Parties in Norway and the United States
A growing body of comparative studies on partisan hostility â a phenomenon known as affective polarization â is providing evidence that partisan affective polarization is generally no greater in the United States than it is in many European multiparty systems. This article takes the comparative literature on affective polarization one step further by presenting the first comparative study on affective polarization that simultaneously uses, compares and combines a direct measure of affective polarization towards voters (using the inter-party marriage measure) and an indirect measure of affective polarization towards parties (using the like/dislike of party measure) while accounting for the fact that multiparty systems have numerous political parties. This is done by comparing the levels of affective polarization in the United States and Norway. The results show greater affective polarization in the United States relating to parties, but the differences between these two countries are indistinguishable from chance when focusing on the affect relating to voters. This provides empirical evidence that comparative evidence of negative affect towards parties cannot necessarily be generalized to suggest that there is comparative evidence of negative affect towards voters. Yet the results also suggest that negative feelings towards out-parties move to some extent to the personal level in terms of negative feelings towards voters of these out-parties.publishedVersio
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Imagined Journalists: New Framework for Studying MediaâAudiences Relationship in Populist Times
These are challenging times for journalistsâ relationship with their audiences. Attacks against âthe mediaâ and the increasing weaponization of social media to harass journalists have drawn the attention of scholars worldwide. In the current climate, journalists are not only distrusted but also hated, which creates a series of distinct ramifications. In this article, we suggest a new framework to study journalistsâaudiences relationship, particularly in times of hostile populism: the imagined journalists approach. A mirror image of the much-studied concept of imagined audiences, imagined journalists refers to the entirety of ideas, feelings, stereotypes, and imaginaries that audiences hold regarding their imagined news producers. It brings together the research on media trust, audiencesâ perceptions, antimedia populism, and the emotional turn in journalismâto generate a comprehensive understanding of peopleâs criticisms, narratives, and priorities. We demonstrate the potential of this approach by analyzing 1,215 responses to an open-ended question regarding journalistsâ traits in Israel in 2021. Employing qualitative and quantitative analyses, we find that: (a) right-wing and pro-populist voters hold more negative views of journalists, as expected; (b) voters express three different types of criticism of journalists (professional, personal, and national)âonly one of which directly relates to their professional conduct; (c) different types of voters express different types of criticism; and (d) while objectivity and bias remain main concerns, democracy is not a dominant factor in respondentsâ thinking on journalists. These findings contribute theoretically and methodologically to future research in the field, as well as to urgent attempts to improve our information environment
Moving beyond European and Latin American Typologies:The Peculiarities of AKPâs Populism in Turkey
Despite the growing literature on Turkish populism, there is yet no consensus on how best to categorise the Justice and Development Party (Adalet ve Kalkınma Partisi or AKP). This article argues that this lack of consensus is due to a selective focus on the attributes of AKPâs populism. Indeed, when the partyâs features are examined holistically, it does not neatly conform to the dominant typologies of populism, which were conceived mostly for European and Latin American examples. For historical reasons, AKPâs populist discourse defines âthe peopleâ versus âthe eliteâ in civilisational terms and combines this with strategies of neo-liberalism, strong party organisation and grassroots mobilisation. This blend of populism distinguishes the AKP case from the exclusionary/inclusionary and classical/neo-liberal/radical typologies previously identified by the literature. However, the Bharatiya Janata Party in India and the Thai Rak Thai Party in Thailand have similar attributes to the AKP, drawing attention to the need to move beyond the existing ideological and strategic approaches to populism and towards a more comprehensive socio-cultural approach. The article contributes to the literature on populism by highlighting possible avenues for further research based on such a comprehensive understanding of populism based also on cases from Asia
Something âOldâ, Something âNewâ? The UK Space of Political Attitudes After the Brexit Referendum
This study focuses on the political attitudes of UK citizens in the aftermath of the âBrexitâ vote. It has been argued that differences within electorates across Europe are found in disputes over taxes, redistribution of wealth and social welfare, as much as in divergent ideas on how to deal with globalisation, migration, and climate change. This article uses the 2016â2017 round of the European Social Survey (Nâ=â1959) to shed light on two important issues in regard to the relationship between âoldâ and ânewâ politics. By using multiple correspondence analysis, we first consider the structure, or dimensionality, of the space of political attitudes in contemporary UK society. Contrary to a prevailing discourse that forwards the argument that postmaterial values constitute an altogether separate political dimension in late modernity, we observe that such values collapse into traditional left/right standpoints. Second, we discuss the connection between class (economic capital, cultural capital, and occupational class) and position-takings in the space of political attitudes. We show that class retains a limited effect on political position-takings, where educational capital plays the most important role. The divisions between the politically interestedâuninterested, oldâyoung, menâwomen, and ruralâurban are more clearly demarcated than differences between people of different social class positions. Furthermore, polarisation is most prevalent between a highly opinionated, relatively resourceful, small minority of the population
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âBirds of a featherâ? Assessing the prevalence of anti-immigration attitudes among the far right electorate
This article focuses on the prevalence of anti-immigration attitudes among the far-right electorate. Drawing on the distinction between the predictive power of immigration concerns, and the question of how widespread these concerns are among the far-right voter pool, we proceed in two steps. First, we assess the extent to which anti-immigration attitudes are a necessary condition for voting far right; and second we examine whether far right voters with different levels of anti-immigration attitudes exhibit similar individual and attitudinal characteristics. Using data from the 8th wave of the European Social Survey (ESS) we find that, surprisingly, anti-immigration attitudes are not a necessary condition for voting for the far right as approximately one third of far-right voters have no concerns over immigration. We further show that far-right voters with different levels of immigration concerns have different profiles when it comes to other predictors of the far right-vote including ideological affinity, attachment to the EU and government satisfaction. Our contribution is significant as we suggest that there are different routes to voting for the far right by groups with different grievances, including non- immigration related
Loneliness, social support and cardiovascular reactivity to laboratory stress
Self-reported or explicit loneliness and social support have been inconsistently associated with cardiovascular reactivity (CVR) to stress. The present study aimed to adapt an implicit measure of loneliness, and use it alongside the measures of explicit loneliness and social support, to investigate their correlations with CVR to laboratory stress. Twenty-five female volunteers aged between 18 and 39 years completed self-reported measures of loneliness and social support, and an Implicit Association Test (IAT) of loneliness. The systolic blood pressure (SBP), diastolic blood pressure (DBP) and heart rate (HR) reactivity indices were measured in response to psychosocial stress induced in the laboratory. Functional support indices of social support were significantly correlated with CVR reactivity to stress. Interestingly, implicit, but not explicit, loneliness was significantly correlated with DBP reactivity after one of the stressors. No associations were found between structural support and CVR indices. Results are discussed in terms of validity of implicit versus explicit measures and possible factors that affect physiological outcomes
Party activism in the populist radical right: The case of the UK Independence Party
Recent decades have seen an upsurge of interest in populist radical right (PRR) parties. Yet despite a large body of research on PRR voters, there are few studies of the internal life of these parties. In particular, there is a dearth of research about why people are active in them. This article uses data from a unique large-scale survey of United Kingdom Independence Party (UKIP) members to investigate if drivers of voting support for these parties are also important for explaining party activism. Analyses show that traditional models of party activism are important for understanding engagement in UKIP, but macro-level forces captured in an expanded relative deprivation model also stimulate participation in the party. That said macro-level forces are not the dominant driver of activism
New Developments in Understanding Cardiovascular Disease and the Implications for Social Work
Cardiovascular disease is now viewed as an inflammatory disease. An index of chronic inflammation (viz., C-Reactive Protein) is as good a predictor of heart attacks as are fats in blood. The data suggest that stressful events are so closely associated with chronic inflammatory states, that the bodyâs stress response can be viewed as an inflammatory state. This paper summarizes and explains the link between stress and cardiovascular disease. Negative health outcomes, particularly for cardiovascular diseases, are higher among those of lower socio-economic status. Differential stress among socio-economic tiers is considered as an explanation for the disparities. The literature linking cardiovascular risk factors to the stressors of workplace unfairness and lack of control over working conditions is reviewed. The role of the stressor of racism in explaining the higher rates of cardiovascular mortality in African Americans is discussed. Finally, for societies with wider gaps in income between the rich and the poor, increased stress is explored as a possible explanation for the diminished health outcomes found across all socio-economic tiers. The implications for social work direct practice and macro-practice are considered
Therapeutic potential of cladribine in combination with STAT3 inhibitor against multiple myeloma
<p>Abstract</p> <p>Background</p> <p>Cladribine or 2-chlorodeoxyadenosine (2-CDA) is a well-known purine nucleoside analog with particular activity against lymphoproliferative disorders, such as hairy cell leukemia (HCL). Its benefits in multiple myeloma (MM) remain unclear. Here we report the inhibitory effects of cladribine on MM cell lines (U266, RPMI8226, MM1.S), and its therapeutic potential in combination with a specific inhibitor of the signal transducer and activator of transcription 3 (STAT3).</p> <p>Methods</p> <p>MTS-based proliferation assays were used to determine cell viability in response to cladribine. Cell cycle progression was examined by flow cytometry analysis. Cells undergoing apoptosis were evaluated with Annexin V staining and a specific ELISA to quantitatively measure cytoplasmic histone-associated DNA fragments. Western blot analyses were performed to determine the protein expression levels and activation.</p> <p>Results</p> <p>Cladribine inhibited cell proliferation of MM cells in a dose-dependent manner, although the three MM cell lines exhibited a remarkably different responsiveness to cladribine. The IC50 of cladribine for U266, RPMI8226, or MM1.S cells was approximately 2.43, 0.75, or 0.18 ÎŒmol/L, respectively. Treatment with cladribine resulted in a significant G1 arrest in U266 and RPMI8226 cells, but only a minor increase in the G1 phase for MM1.S cells. Apoptosis assays with Annexin V-FITC/PI double staining indicated that cladribine induced apoptosis of U266 cells in a dose-dependent manner. Similar results were obtained with an apoptotic-ELISA showing that cladribine dramatically promoted MM1.S and RPMA8226 cells undergoing apoptosis. On the molecular level, cladribine induced PARP cleavage and activation of caspase-8 and caspase-3. Meanwhile, treatment with cladribine led to a remarkable reduction of the phosphorylated STAT3 (P-STAT3), but had little effect on STAT3 protein levels. The combinations of cladribine and a specific STAT3 inhibitor as compared to either agent alone significantly induced apoptosis in all three MM cell lines.</p> <p>Conclusions</p> <p>Cladribine exhibited inhibitory effects on MM cells <it>in vitro</it>. MM1.S is the only cell line showing significant response to the clinically achievable concentrations of cladribine-induced apoptosis and inactivation of STAT3. Our data suggest that MM patients with the features of MM1.S cells may particularly benefit from cladribine monotherapy, whereas cladribine in combination with STAT3 inhibitor exerts a broader therapeutic potential against MM.</p
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