The Effect of Social Networking on Grief

Death and loss are complicated issues. They are further complicated by the Internet and the increased usage of social media; however, there is little research on the effects of social media on grief. This project\u27s goal was to gather information about grieving via online social networking sites. Data was collected from 20 in memoriam profile webpages on Facebook and MySpace. The deceased were between the ages of six months and 32 years. Results indicate that society is using social media as a form of support and comfort in times of loss

Sultones and Sultines via a Julia-Kocienski Reaction of Epoxides

We thank the EPSRC/Syngenta for a CASE Ph.D. Studentship (to G.M.T.S. under grant EP/J50029X/1), the EPSRC UK National Mass Spectrometry Facility at Swansea University and the EPSRC UK National Crystallography Service Facility at Southampton University.37 We are indebted to Andrew Plant and Janice Black (Syngenta) for the initial suggestion of using the combination of LiN(SiMe3)2/CH2Cl2 and Matthew Reid (Syngenta) for NMR assistance

Technology Use and Its Association With Romantic Relationships

The present study explored the demographics and associations between the use of technology and romantic relationships among 171 young adults. Participants completed a self-administered anonymous, online survey that included 66 questions assessing demographic information, use of technology, sexting activity, and sexual behaviors. Crosstabs were performed between demographic factors and questions assessing online engagement with romantic partners. A chi-square test for independence (with Yates Continuity Correction) was done among the remaining questions on Internet use and demographic variables, with the exception of age. Independent-samples t-tests were conducted to compare age with the questions posed on how technology influences romantic relationships. The authors used Bronfenbrenner’s bioecological model and Johnson’s addition of the technosubsystem to examine the influence of the Internet on relationships. Results showed variation with the Internet’s impact on close relationships by ethnicity; Caucasians were more likely to see the Internet as increasing their relationship while African Americans saw it as negatively impacting it. In addition, men were more likely to use technology to maintain long-distance relationships, as well as search for a partner, flirt, and ask a partner out online. As relational scientists, it is particularly important to understand if and how interpersonal relationships are affected by the use of technology. Suggestions are provided on how to guide partners toward healthy relationships by managing the impact of technology. Studying the current trends in technology to better understand modern relationships is critical to future social scientists and relationship helpers

Direct synthesis of fluorinated heteroarylether bioisosteres

(Bioiso)steering in a new direction: A modular synthesis of reagents (e.g. sodium difluoroethylsulfinate) that can be used for the direct incorporation of difluoroalkyl groups onto heterocycles is reported. The scope and generality of the incorporation of difluoroalkyl groups is exemplified with the difluoroethyl group and a proof of principle is shown for a general synthesis of fluorinated heteroarylether bioisosteres

Alkyl and Aryl Thiol Addition to [1.1.1]Propellane : Scope and Limitations of a Fast Conjugation Reaction

Herein the addition of different thiols to the strained carbon-carbon bond of [1.1.1]propellane (1) is reported. The reaction pathway was investigated, addition reactions with substituted thiols, hydrogen sulfide and protected cysteine were performed, and further modifications of the products were verified. The clean reaction proceeds by a radical chain process, which was confirmed by different deuterium labelling experiments. It shows high functional-group tolerance, since halo-, hydroxy-, methoxy-, carboxy-, amino- and nitro-substituted thiols could be added to 1 with few by-products in 16-90% yield. Oxidation of the products allows tuning of the polarity and subsequent reactions of the products. The click-type reaction proceeds even faster with selenols, as was shown in a proof of concept. Thiol addition to 1 offers a facile tool for surface modification, conjugation and tuning of hydrophilicity in bio- and medicinal chemistry.Peer reviewe

Synthesis and indole coupling reactions of azetidine and oxetane sulfinate salts

Azetidine and oxetane sulfinate salts are easily prepared from commercially available 3-iodoheterocycle precursors in a three-step sequence. They undergo smooth coupling reactions thereby providing an expedient route for the introduction of these four-membered heterocycles into indoles