Çevik yöntemlerde cosmic i̇şlev puanı ve hikaye puanının birlikte kullanımı

Hikaye Puanı (SP: Story Point), Scrum ve Kanban gibi çevik yöntemlerde kullanılan en yaygın metriklerden birisidir. Subjektif bir metrik olsa da kullanışlı ve basit olması nedeniyle çevik ekiplerin birikim listelerinde bulunan kullanıcı hikayelerinin uygun bölümlere ayrılmasında, maliyet tahminlemesinde ve ekiplerin hız ve kapasitelerinin hesaplanmasında yaygın bir şekilde kullanılmaktadır. Cosmic işlev puanı (CFP: Cosmic Function Point) ise yazılım işlevsel kapsam büyüklüğünün ölçümünde kullanılan ve aynı zamanda bir ISO standardı da (ISO 19761) olan objektif bir metriktir. Bu çalışmada Türkiye’nin en büyük teknoloji ve iletişim hizmetleri sağlayıcı firmalarından birinin çevik yazılım geliştirme prensiplerine göre çalışırken hem Hikaye Puanı hem de CFP metriklerini birlikte kullanım deneyimleri paylaşılmış; iki metriğin benzerlikleri ve farklılıkları irdelenmiştir. Sonuç olarak SP metriğinin kapsam boyutlandırma toplantıları sırasında kullanıcı hikayelerinin çevik mantıkla uygun kapsam büyüklüğüne bölünmesinde daha etkin bir araç olduğu, CFP’nin ise çevik ekiplerin ürettiği çıktıların miktarının ve kalitesinin zaman içindeki trendinin ölçülmesinde ve yine çevik ortamlarda dış kaynak hak edişlerinin belirlenmesinde daha başarılı sonuçlar verdiği sonucuna varılmıştır. Ek olarak CFP’nin Efor tahminlemesinde kullanılıp kullanılamayacağı yönünde bir doğrusal regresyon modeli için ön analiz yapılmış ve ilk sonuçlar paylaşılmıştır.Story Point (SP) is one of the most common metric in agile frameworks such as Scrum and Kanban. Although being subjective, story point is very useful for grooming and sizing of the backlog items, cost, squad velocity and capacity estimation. Cosmic Functional Points (CFP) is an objective metric used for estimating the functional scope of the software and it is an ISO standard (ISO 19761). This study investigates the use, similarities and differences of boh SP and CFP in agile software development practices in the largest technology and communications provider of Turkey. As a result, SP is an effective tool for grooming the user stories whereas CFP provides successful results for measuring output of the squad, quality trend and outsource contracts. Also, a preanalysis for a linear regression model of CFP versus effort estimation is conducted in this paper and the initial results are shared.Publisher versio

Çevik yöntemlerde cosmic i̇şlev puanı ve hikaye puanının birlikte kullanımı

Hikaye Puanı (SP: Story Point), Scrum ve Kanban gibi çevik yöntemlerde kullanılan en yaygın metriklerden birisidir. Subjektif bir metrik olsa da kullanışlı ve basit olması nedeniyle çevik ekiplerin birikim listelerinde bulunan kullanıcı hikayelerinin uygun bölümlere ayrılmasında, maliyet tahminlemesinde ve ekiplerin hız ve kapasitelerinin hesaplanmasında yaygın bir şekilde kullanılmaktadır. Cosmic işlev puanı (CFP: Cosmic Function Point) ise yazılım işlevsel kapsam büyüklüğünün ölçümünde kullanılan ve aynı zamanda bir ISO standardı da (ISO 19761) olan objektif bir metriktir. Bu çalışmada Türkiye’nin en büyük teknoloji ve iletişim hizmetleri sağlayıcı firmalarından birinin çevik yazılım geliştirme prensiplerine göre çalışırken hem Hikaye Puanı hem de CFP metriklerini birlikte kullanım deneyimleri paylaşılmış; iki metriğin benzerlikleri ve farklılıkları irdelenmiştir. Sonuç olarak SP metriğinin kapsam boyutlandırma toplantıları sırasında kullanıcı hikayelerinin çevik mantıkla uygun kapsam büyüklüğüne bölünmesinde daha etkin bir araç olduğu, CFP’nin ise çevik ekiplerin ürettiği çıktıların miktarının ve kalitesinin zaman içindeki trendinin ölçülmesinde ve yine çevik ortamlarda dış kaynak hak edişlerinin belirlenmesinde daha başarılı sonuçlar verdiği sonucuna varılmıştır. Ek olarak CFP’nin Efor tahminlemesinde kullanılıp kullanılamayacağı yönünde bir doğrusal regresyon modeli için ön analiz yapılmış ve ilk sonuçlar paylaşılmıştır.Story Point (SP) is one of the most common metric in agile frameworks such as Scrum and Kanban. Although being subjective, story point is very useful for grooming and sizing of the backlog items, cost, squad velocity and capacity estimation. Cosmic Functional Points (CFP) is an objective metric used for estimating the functional scope of the software and it is an ISO standard (ISO 19761). This study investigates the use, similarities and differences of boh SP and CFP in agile software development practices in the largest technology and communications provider of Turkey. As a result, SP is an effective tool for grooming the user stories whereas CFP provides successful results for measuring output of the squad, quality trend and outsource contracts. Also, a preanalysis for a linear regression model of CFP versus effort estimation is conducted in this paper and the initial results are shared.Publisher versio

Towards a novel framework of barriers and drivers for digital transformation in industrial supply chains

© 2019 PICMET. Businesses across all sectors are facing the complexity of an increasingly digital economy. Digital transformation offers vast opportunities to businesses and entire supply chains. While many investments are targeted at the organization level, the supply chain perspective can lead to even greater impacts on business performance. However, as supply chains involve interconnections between multiple actors, comprehensive digitalization initiatives at this level are very complex. Several strategic factors affect decision-making around digital investments. For this reason, a framework that categorizes all these factors is needed in order to help managers build digitalization strategies for their supply chains. In this paper, based on a review of existing literature, we give indications for a framework encompassing barriers to and drivers for digital transformation in the context of industrial supply chains. Our framework preliminarily allocates these factors by using two dimensions. The first one classifies them using several categories: financial, knowledge and skills, regulatory, technological, market, organizational, and cultural. The second dimension classifies determinants at the level on which actions can be made, i.e. market, supply chain, or organization. The framework can support organizations to exploit the opportunities provided by digitalization of supply chains and will help managers understand the complexity involved

Diversity in Secondary Metabolites Including Mycotoxins from Strains of <i>Aspergillus </i>Section <i>Nigri </i>Isolated from Raw Cashew Nuts from Benin, West Africa

<p>In a previous study, raw cashew kernels were assayed for the fungal contamination focusin on strains belonging to the genus Aspergillus and on aflatoxins producers. These sample showed high contamination with Aspergillus section Nigri species and absence o aflatoxins. To investigate the diversity of secondary metabolites, including mycotoxins, th species of A. section Nigri may produce and thus threaten to contaminate the raw cashe kernels, 150 strains were isolated from cashew samples and assayed for their productio of secondary metabolites using liquid chromatography high resolution mass spectrometr (LC-HRMS). Seven species of black Aspergilli were isolated based on morphological an chemical identification: A.Tubingensis (44%), A. niger (32%), A. brasiliensis (10%), A. carbonariu (8.7%), A. luchuensis (2.7%), A. aculeatus (2%) and A. aculeatinus (0.7%). Fro these, 45 metabolites and their isomers were identified. Aurasperone and pyranonigrin A produced by all species excluding A. aculeatus and A. aculeatinus, were most prevalen and were encountered in 146 (97.3%) and 145 (95.7%) isolates, respectively. Three mycotoxin groups were detected: fumonisins (B2 and B4) (2.7%) ochratoxin A (13.3%), an secalonic acids (2%), indicating that these mycotoxins could occur in raw cashew nuts Thirty strains of black Aspergilli were randomly sampled for verification of species identit based on sequences of β-Tubulin and calmodulin genes. Among them, 27 isolates wer positive to the primers used and 11 were identified as A. niger, 7 as A.Tubingensis, 6 as A carbonarius, 2 as A. luchuensis and 1 as A. welwitschiae confirming the species names a based on morphology and chemical features. These strains clustered in 5 clades in A. sectio Nigri. Chemical profile clustering also showed also 5 groups confirming the speciespecific metabolites production.</p

Oxidative stress responses in watermelon (Citrullus lanatus) as influenced by boron toxicity and drought

This study aimed to investigate the effect of different boron (B) treatments on drought tolerance of watermelon plants. Drought tolerant Citrullus lanatus (Thunb.) Matsum. et Nakai genotype ‘Kar 98’ was grown in controlled greenhouse conditions hydroponically and exposed to drought stress by applying PEG 6000 (polyethylene glycol) in the presence of three boron dosages: 0.05, 0.25 and 1.25 mM. Growth parameters (fresh weight, dry weight and lengths of shoot and roots), leaf relative water content, boron accumulation, lipid peroxidation level and activities of superoxide dismutase (SOD), catalase (CAT) and glutathione reductase (GR) enzymes were determined as well as the accumulation of hydrogen peroxide (H2O2) and hydroxyl (•OH)-scavenging activity were assayed. Increasing dosages of boron alone caused more severe growth reduction than combined with PEG 6000-induced drought stress. Induced drought stress caused less accumulation of boron in leaves and roots. B concentration of 1.25 mM caused lipid peroxidation in a reactive oxygen species-independent manner and drought stress-induced lipid peroxidation was alleviated by increasing B dosages. Induced glutathione reductase activity under the combination of 1.25 mM B and PEG 6000-induced drought stress seemed an important physiological response in ‘Kar 98’ plants against multiple stresses

The Effects of Post-Surgical Administration of Goserelin Plus Anastrozole Compared to Goserelin Alone in Patients with Severe Endometriosis: A Prospective Randomized Trial

BACKGROUND: Among patients using GnRH analogues for endometriosis it has been postulated that peripheral and inflammation-induced in-situ aromatization of adrenal androgens are probably the main reasons for the high rates of failure during follow-up. We hypothesized that in cases with premenopausal severe endometriosis, use of a combination of anastrozole and goserelin to achieve almost maximal endocrine blockade of estrogen synthesis after conservative surgery may increase the pain-free interval and reduce the recurrence rates as compared to goserelin alone. METHODS: In a prospective randomized trial, we evaluated the efficacy of using either a combination of anastrozole and goserelin for 6 months or goserelin alone for 6 months after conservative surgery for severe endometriosis. The primary outcome measures were the symptom recurrence rates and the impact of treatment on endometriosis-related multidimensional score. The secondary outcome measures were the impact of allocated treatment regimens on menopausal quality of life and on lumbar spine bone mineral density (BMD). RESULTS: When we analyzed the Kaplan-Meier survival curves, we detected a statistically significant advantage of goserelin plus anastrozole as compared to goserelin only, in terms of the median time to detect symptom recurrence (>2.4 versus 1.7 months; log-rank test; P = 0.0089). This statistically significant advantage occurred with a relative risk of 4.3 [95% confidence interval (CI) 1.3-9.8]. Three cases out of 40 recurred in the goserelin plus anastrozole arm (7.5%), whereas we detected recurrences in 14 cases out of 40 cases in the goserelin-only arm (35%) during the follow-up period of 24 months. Based on these data, the interpretation of Kaplan-Meier curves indicates that at the end of follow-up, 54.7 versus 10.4%, respectively, of the patients were free of recurrence. The mean of the differences in terms of Deltabaseline-24 months post-medical therapy multidimensional score were statistically significant in favour of goserelin and anastrozole (9.2 +/- 2.1 versus 6.7 +/- 2.8; paired t-test; P < 0.0001; 95% CI 1.5-4.0). We observed a statistically significant difference in suppression of estradiol concentrations and a significantly greater BMD loss at the end of treatment in the goserelin and anastrozole arm as compared to goserelin-only arm. However, this did not elicit deterioration in menopausal quality of life and the observed bone loss was not significant in terms of &UDelta;BMD between the groups at 2 years of treatment withdrawal. CONCLUSIONS: Six months of treatment with anastrozole and goserelin as compared to goserelin alone increased the pain-free interval and decreased symptom recurrence rates in patients following surgery for severe endometriosis. Furthermore, menopausal quality of life and BMD at 2 years after medical therapy remained unaffectedWoSScopu

The effects of post-surgical administration of goserelin plus anastrozole compared to goserelin alone in patients with severe endometriosis: a prospective randomized trial.

BACKGROUND: Among patients using GnRH analogues for endometriosis it has been postulated that peripheral and inflammation-induced in-situ aromatization of adrenal androgens are probably the main reasons for the high rates of failure during follow-up. We hypothesized that in cases with premenopausal severe endometriosis, use of a combination of anastrozole and goserelin to achieve almost maximal endocrine blockade of estrogen synthesis after conservative surgery may increase the pain-free interval and reduce the recurrence rates as compared to goserelin alone. METHODS: In a prospective randomized trial, we evaluated the efficacy of using either a combination of anastrozole and goserelin for 6 months or goserelin alone for 6 months after conservative surgery for severe endometriosis. The primary outcome measures were the symptom recurrence rates and the impact of treatment on endometriosis-related multidimensional score. The secondary outcome measures were the impact of allocated treatment regimens on menopausal quality of life and on lumbar spine bone mineral density (BMD). RESULTS: When we analyzed the Kaplan-Meier survival curves, we detected a statistically significant advantage of goserelin plus anastrozole as compared to goserelin only, in terms of the median time to detect symptom recurrence (>2.4 versus 1.7 months; log-rank test; P=0.0089). This statistically significant advantage occurred with a relative risk of 4.3 [95% confidence interval (CI) 1.3-9.8]. Three cases out of 40 recurred in the goserelin plus anastrozole arm (7.5%), whereas we detected recurrences in 14 cases out of 40 cases in the goserelin-only arm (35%) during the follow-up period of 24 months. Based on these data, the interpretation of Kaplan-Meier curves indicates that at the end of follow-up, 54.7 versus 10.4%, respectively, of the patients were free of recurrence. The mean of the differences in terms of Deltabaseline-24 months post-medical therapy multidimensional score were statistically significant in favour of goserelin and anastrozole (9.2 +/- 2.1 versus 6.7 +/- 2.8; paired t-test; P<0.0001; 95% CI 1.5-4.0). We observed a statistically significant difference in suppression of estradiol concentrations and a significantly greater BMD loss at the end of treatment in the goserelin and anastrozole arm as compared to goserelin-only arm. However, this did not elicit deterioration in menopausal quality of life and the observed bone loss was not significant in terms of DeltaBMD between the groups at 2 years of treatment withdrawal. CONCLUSIONS: Six months of treatment with anastrozole and goserelin as compared to goserelin alone increased the pain-free interval and decreased symptom recurrence rates in patients following surgery for severe endometriosis. Furthermore, menopausal quality of life and BMD at 2 years after medical therapy remained unaffected

Response of common bean (Phaseolus vulgaris L.) cultivars to foliar and soil applied boron in borondeficient calcareous soils

Yield losses in common bean (Phaseolus vulgaris L.) may occur due to boron (B) deficiency when the susceptible cultivars are grown in calcareous boron deficient soils. The study was therefore aimed atinvestigating the effects of three B doses: control (0.0 kg ha-1), soil application (3.0 kg ha-1) and foliar fertilization (0.3 kg ha-1) on yield and some yield components of six common bean genotypes in the Bdeficient soil (with available 0.19 mg B kg-1). Plant height, pods per plant, seeds per pod, seed yield, protein content, 100-seed weight and B concentration in leaf were studied. Yield was obtained higher Bapplied genotypes than those of check. Applications both of soil and foliar B increased yield average of 10 and 20%, respectively. Genotypes had the highest seed yield when B was foliar applied indicating that soil factors affected available B. The highest seed yield was obtained from Karacaehir-90 with 4078.2 kg ha-1. Yunus-90 was found to be B tolerant, while the other genotypes appeared to be highly B sensitive. The result showed that B deficiency in common bean might lead to significant yield losses and foliar application should be advised