The effect of hypodynamia on the structure of the intraorganic blood vessels and the capacity of the blood stream in the diaphragm of white rats

The effect of hypodynamia on the vascular system of white rats with diaphragm deprivation was investigated. Morphological changes in the intraorganic blood stream of the diaphragm were determined. The capacity of the intraorganic vascular flow within the diaphragm muscles was established

Managing Illness through Creative Engagement: Women, HIV, and the Stitches Doll Project

The Stitches Doll Project is a community-based initiative that enables women and girls to express their feelings about living with HIV/AIDS through creating a doll that speaks for them. In a very personal and powerful way, women and girls are able to tell their stories both visually, through their dolls, and verbally/non-verbally, through their dolls’ monographs. The completed dolls become part of an online and traveling oral history exhibit. Based on an analysis of the dolls and their monographs, interviews with doll contributors and project coordinators, and archived Stitches materials, this paper explores the meaning making and identity work/repair articulated through textile creation and the cultural transmission of oral histories. Our analysis reveals four recurrent message themes: making sense of infection, the impact of HIV, the role of social support and connection, and educating others. These themes speak to the nature of the oral history the artists transmit via their dolls. As they design their contribution to the project at Stitches workshops, the healing benefits of creative engagement through textile artwork is made available to them. It is these two components of the project in combination that afford doll makers a unique opportunity to engage in a process of meaning making and identity work/repair. In the process they help advance public education efforts by challenging cultural beliefs regarding “the face of AIDS,” the experience of living with HIV/AIDS, and ultimately who is at risk for acquiring the virus and by poignantly calling attention to the variety of social factors (e.g., poverty, domestic violence, and sexual abuse and assault) that put women at risk for contracting HIV

Properties of Nanoscale Carbon Coatings Obtained by the Pulsed Vacuum-Arc Method on Silicon

The complex of properties including the structure, adhesive strength, internal stresses, tribological properties, microhardness and crack-resistance of nanoscale carbon coatings obtained by the pulsed vacuum-arc method on single-crystal silicon substrates was investigated. Two types of samples of the carbon coating: type (i) formed at the normal location of the substrate relative to the geometric axis of the plasma flow (θ = 0°); type (ii) obtained at an angle θ = 70° were studied. The analysis of the experimental results showed, that the angle of plasma flow incidence relative to the substrate drastically affects the properties of carbon coatings. The structure, adhesion, internal stresses, wear resistance, crack resistance are interrelated and determined by the radiation-diffusion sealing during the process of carbon coating deposition from the carbon plasma flow. Nanoscale carbon coatings can significantly improve the strength and tribological properties of different tools, parts and products. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/3530

A Study of Public Accounting and Related Economic Concepts

This thesis consists of several case studies relating to different topics within the world of accounting. These cases were completed as assignments within the thesis practicum class taught by Dr. Victoria Dickinson. Each case pertains to a different accounting-related topic, and topics include the fundamentals of accounting as well as recent events in the business world. The thesis also includes a five-week long case competition in which students were put into groups to present Audit, Tax, and Advisory strategies for companies headquartered in the United States. Each of these cases were completed during the course of the Fall 2020 and Spring 2021 semesters. Because each case is independent from the others, cases in which outside sources were cited contain their own bibliographies. In addition to assigned cases, summaries of presentations given by accounting professionals invited to speak to the class are included as well

Tibiofemoral Contact Forces in the Anterior Cruciate Ligament-Reconstructed Knee.

PURPOSE: To investigate differences in ACL reconstructed (ACLR) and healthy individuals in terms of the magnitude of the tibiofemoral contact forces, as well as the relative muscle and external load contributions to those contact forces, during walking, running and sidestepping gait tasks. METHODS: A computational electromyography-driven neuromusculoskeletal model was used to estimate the muscle and tibiofemoral contact forces in those with combined semitendinosus and gracilis tendon autograft ACLR (n=104, 29.7±6.5 years, 78.1±14.4 kg) and healthy controls (n=60, 27.5±5.4 years, 67.8±14.0 kg) during walking (1.4±0.2 ms), running (4.5±0.5 ms) and sidestepping (3.7±0.6 ms). Within the computational model, the semitendinosus of ACLR participants was adjusted to account for literature reported strength deficits and morphological changes subsequent to autograft harvesting. RESULTS: ACLRs had smaller maximum total and medial tibiofemoral contact forces (~80% of control values, scaled to bodyweight) during the different gait tasks. Compared to controls, ACLRs were found to have a smaller maximum knee flexion moment, which explained the smaller tibiofemoral contact forces. Similarly, compared to controls, ACLRs had both a smaller maximum knee flexion angle and knee flexion excursion during running and sidestepping, which may have concentrated the articular contact forces to smaller areas within the tibiofemoral joint. Mean relative muscle and external load contributions to the tibiofemoral contact forces were not significantly different between ACLRs and controls. CONCLUSION: ACLRs had lower bodyweight-scaled tibiofemoral contact forces during walking, running and sidestepping, likely due to lower knee flexion moments and straighter knee during the different gait tasks. The relative contributions of muscles and external loads to the contact forces were equivalent between groups

The local crystallization in nanoscale diamond-like carbon films during annealing

The local crystallization during annealing at 600° C in nanoscale diamond-like carbon coatings films grown by pulsed vacuum-arc deposition method was observed using modern techniques of high-resolution transmission electron microscopy. The crystallites formed by annealing have a face-centred cubic crystal structure and grow in the direction [011] as a normal to the film surface. The number and size of the crystallites depend on the initial values of the intrinsic stresses before annealing, which in turn depend on the conditions of film growth. The sizes of crystallites are 10 nm for films with initial compressive stresses of 3 GPa and 17 nm for films with initial compres- sive stresses of 12 GPa. Areas of local crystallization arising during annealing have a structure dif- ferent from the graphit

Електрофільні реакції 7-(трифлуорометил)-2,3-дигідро-1H-піролізину – шлях до нових будівельних блоків

Aim. To synthesize new fluoro-containing building blocks for medicinal chemistry purposes using electrophilic reactions of 7-(trifluoromethyl)-2,3-dihydro-1H-pyrrolizine.Results and discussion. Synthetic approaches to 5-halogeno- and 5-acyl-7-(trifluoromethyl)-2,3-dihydro-1H-pyrrolizines have been developed. The obtained new trifluoromethyl-containing pyrrolyzines are promising building blocks for medicinal chemistry.Experimental part. The synthesis of the target compounds began with known 7-(trifluoromethyl)-2,3-dihydro-1H-pyrrolizine and included halogenation and acylation reactions using N-halogen succinimides and acylating reagents.Conclusions. New synthetic approaches to a number of 7-(trifluoromethyl)-2,3-dihydro-1H-pyrrolizines with various substituents, such as halogen atoms or acyl groups, at the position 5 of the pyrrole ring have been developed. This opens the door to the use of such promising trifluoromethyl-containing building blocks for medicinal chemistry needs.Мета. Синтезувати нові флуоровмісні будівельні блоки для потреб медичної хімії за допомогою електрофільних реакцій 7-(трифлуорометил)-2,3-дигідро-1H-піролізину.Результати та їх обговорення. Було розроблено синтетичні підходи до 5-галогено- та 5-ацил-7-(трифлуорометил)-2,3-дигідро-1H-піролізинів. Отримані нові трифлуорометил-вмісні піролізини є перспективними будівельними блокамидля медичної хімії.Експериментальна частина. Синтез цільових сполук було здійснено на основі відомого 7-(трифлуорометил)-2,3-дигідро-1H-піролізину з використанням реакцій галогенування та ацилювання дією N-галогеносукцинімідів і ацилювальних реагентів.Висновки. Розроблено нові синтетичні підходи до одержання ряду 7-(трифлуорометил)-2,3-дигідро-1H-піролізинів з різноманітними замісниками: атомами галогенів або ацильними групами в положенні 5 пірольного циклу. Це дозволяє використовувати синтезовані речовини як перспективні трифлуорометилвмісні будівельні блоки в дослідженнях у царині медичної хімії