Modified Recycled Glass as an Additive in Coatings Applications

The feasibility of using chemically modified, finely pulverized recycled glass as an additive in coatings was investigated. The ground glass was added as partial replacement for the conventional pigment titanium dioxide (TiO2). The loss of TiO2 pigment was compensated with an optical brightening agent (OB agents). OB agents can help contribute to a coating’s hiding capacity by absorbing light in the UV range, releasing light of a lower energy in the visible spectrum. Glass supplemented coatings were formulated and common paint tests were performed. The glass changed the optical and physical properties of the coating formulations. The results of the project demonstrated the feasibility of using recycled glass as an additive in coatings

Jet Fractions in e+e- Annihilation

The jet fractions expected in e+e- annihilation are calculated analytically in the leading log approximation up to 6 jet order for both the JADE and Durham algorithms.Comment: 19 pages, 2 figure

Constituting neoliberal subjects? ‘Aspiration’ as technology of government in UK policy discourse

Since the 2000s, successive governments in the United Kingdom and elsewhere have embraced the idea of ‘raising aspiration’ among young people as a solution to persisting educational and socio-economic inequalities. Previous analyses have argued that these policies tend to individualise structural disadvantage and promote a ‘deficit’ view of working-class youth. This paper adopts a novel approach to analysing aspiration discourses combining Michel Foucault’s four dimensions of ‘ethics’ and Mitchell Dean’s notion of ‘formation of identities’. Applying Foucault’s and Dean’s work in this way provides a new lens that enables an examination of how policy encourages particular forms of subjectivation, and, therefore, seeks to govern individuals. The findings presented in the paper complicate previous research by showing that raising aspiration strategies portray disadvantaged youth both in terms of ‘deficit’ and ‘potential’, resulting in a requirement for inner transformation and mobility through attitudinal change. The paper concludes with a discussion of the implications for the identity formation of young people and for conceptualising contemporary forms of governmentality

Preparation of ordered nanocomposites in polymeric templates swollen by supercritical carbon dioxide.

Nanocomposites are of interest for numerous applications such as catalysis, photonic band gap materials, and waveguides. Ionomers and diblock copolymers have previously been used as templates for ordered nanocomposites. However, these processes have been limited to reactions within thin films or coprecipitation methods from solution due to mass transport limitations of ceramic and metallic precursors within the solid templates. This issue has been addressed by fabricating ordered nanocomposites using phase selective deposition of precursors into supercritical carbon dioxide (SC-CO2) swollen polymeric templates. SCCO2 is an effective plasticizing agent for most polymers and enhances mass transport of the precursors into polymeric templates while preserving the initial template morphology. By proper choice of template material, the precursor can be selectively bound within one phase of the template and reacted to produce the desired material. The resulting composite contains nanoparticles arranged in an ordered morphology dictated by the template over bulk dimensions. Polymer/ceramic and polymer/metal nanocomposites have been successfully synthesized using this technique

A Mixed-Method Multiple Case Study of Three Business Models for Local Healthy Food Delivery Systems in Underprivileged Urban Areas

Define a USDA food desert Analyze the three business models for benefits and deficiencies Identify methods for starting a sustainable mobile farmers market program. Over 40% of Berrien County Michigan land use is agricultural. Many products are fruits and vegetables. Yet, the county has six identified USDA defined Food Deserts. Past research, based on a mobile farmers market, confirmed local trends and deficits. The purpose for this research is to define a sustainable business model that delivers healthy local food options to USDA Food Deserts combating food inequity. A mixed method multiple case study was created to test three business models in one of the local Food Deserts. Results identify a sustainable model that provides local healthy food options. Model One developed lunchtime stops serving robust local businesses and community epicenters, with a goal of creating lunchtime profit, focusing evenings on service stops at a potential loss. Model Two required local farmers to provide produce at no cost to the market. Market locations were service stops embedded inside the residential community and stops increased to 15 per week. Model Three purchased local produce and focused stops on work and shopping locals, targeting the ALICE poverty segment. Models were tested for two weeks each with data collected for correlational comparison. Results show a high demand for lunch hour food options. Labor at such stops was increased over service stops. Model Two proved willingness from local farmers to support neighboring Food Deserts, yet sales didn’t equal market costs. Model Three demonstrated increased demand from ALICE segments. Conclusions indicate that sustainability could be reached with a hybrid model with limited volunteer intern positions. A three to five-year plan should be built with funding support ebbing with market growth

Protocol for expansion of an existing national monthly survey of smoking behaviour and alcohol use in England to Scotland and Wales:The Smoking and Alcohol Toolkit Study

Background The Smoking and Alcohol Toolkit Study (STS/ATS) in England has delivered timely insights to inform and evaluate strategies aimed at reducing tobacco smoking- and alcohol-related harm. From the end of 2020 until at least 2024 the STS/ATS is expanding to Scotland and Wales to include all constituent nations in Great Britain. Expanding data collection to Scotland and Wales will permit the evaluation of how smoking and alcohol related behaviours respond to divergent policy scenarios across the devolved nations. Methods The STS/ATS consists of monthly cross-sectional household interviews (computer or telephone assisted) of representative samples of adults in Great Britain aged 16+ years. Commencing in October 2020 each month a new sample of approximately 1700 adults in England, 450 adults in Scotland and 300 adults in Wales complete the survey (~n = 29,400 per year). The expansion of the survey to Scotland and Wales has been funded for the collection of at least 48 waves of data across four years. The data collected cover a broad range of smoking and alcohol-related parameters (including but not limited to smoking status, cigarette/nicotine dependence, route to quit smoking, prevalence and frequency of hazardous drinking, attempts and motivation to reduce alcohol consumption, help sought and motives for attempts to reduce alcohol intake) and socio-demographic characteristics (including but not limited to age, gender, region, socio-economic position) and will be reviewed monthly and refined in response to evolving policy needs and public interests. All data analyses will be pre-specified and available on a free online platform. A dedicated website will publish descriptive data on important trends each month. Discussion The Smoking and Alcohol Toolkit Study will provide timely monitoring of smoking and alcohol related behaviours to inform and evaluate national policies across Great Britain

Quantification of recombinant and platelet P2Y1 receptors utilizing a [125I]-labeled high-affinity antagonist 2-iodo-N6-methyl-(N)-methanocarba-2′-deoxyadenosine-3′,5′-bisphosphate ([125I]MRS2500)

The ADP-activated P2Y1 receptor is broadly expressed and plays a crucial role in ADP-promoted platelet aggregation. We previously synthesized 2-iodo-N6-methyl–(N)-methanocarba-2′-deoxyadenosine 3′,5′-bisphosphate (MRS2500), as a selective, high affinity, competitive antagonist of this receptor. Here we report utilization of a trimethylstannyl precursor molecule for the multistep radiochemical synthesis of a [125I]-labeled form of MRS2500. [125I]MRS2500 bound selectively to Sf9 insect cell membranes expressing the human P2Y1 receptor but did not specifically bind to membranes isolated from empty vector-infected cells. Binding of [125I]MRS2500 to P2Y1 receptors was saturable with a Kd of 1.2 nM. Known agonists and antagonists of the P2Y1 receptor inhibited [125I]MRS2500 binding to P2Y1 receptor-expressing membranes with potencies in agreement with those previously observed in functional assays of this receptor. A high-affinity binding site for [125I]MRS2500 also was observed on intact human platelets (Kd = 0.61 nM) and mouse platelets (Kd = 1.20 nM) that exhibited the pharmacological selectivity of the P2Y1 receptor. The densities of sites observed were 151 sites/platelet and 229 sites/platelet in human and mouse platelets, respectively. In contrast, specific binding was not observed in platelets isolated from P2Y1 receptor (−/−) mice. Taken together, these data illustrate the synthesis and characterization of a novel P2Y1 receptor radioligand and its utility for examining P2Y1 receptors natively expressed on human and mouse platelets

The Star Formation Rate-Density Relation at 0.6<z<0.9 and the Role of Star Forming Galaxies

We study the star formation rates (SFRs) of galaxies as a function of local galaxy density at 0.6<z<0.9. We used a low-dispersion prism in IMACS on the 6.5-m Baade (Magellan I) telescope to obtain spectra and measured redshifts to a precision of sigma_z/(1+z)=1% for galaxies with z<23.3 AB mag. We utilized a stellar mass-limited sample of 977 galaxies above M>1.8x10^{10} Msun to conduct our main analysis. With three different SFR indicators, (1) Spitzer MIPS 24-micron imaging, (2) SED fitting, and (3) [OII]3727 emission, we find the median specific SFR (SSFR) and SFR to decline from the low-density field to the cores of groups and a rich cluster. For the SED and [OII] based SFRs, the decline in SSFR is roughly an order of magnitude while for the MIPS based SFRs, the decline is a factor of ~4. We find approximately the same magnitude of decline in SSFR even after removing the sample of galaxies near the cluster. Galaxies in groups and a cluster at these redshifts therefore have lower star formation (SF) activity than galaxies in the field, as is the case at z~0. We investigated whether the decline in SFR with increasing density is caused by a change in the proportion of quiescent and star forming galaxies (SFGs) or by a decline in the SFRs of SFGs. Using the rest-frame U-V and V-J colors to distinguish quiescent galaxies from SFGs we find the fraction of quiescent galaxies increases from ~32% to 79% from low to high density. In addition, we find the SSFRs of SFGs, selected based on U-V and V-J colors, to decline with increasing density by factors of ~5-6 for the SED and [OII] based SFRs. The MIPS based SSFRs for SFGs decline with a shallower slope. The order of magnitude decline in the SSFR-density relation at 0.6<z<0.9 is therefore driven by both a combination of declining SFRs of SFGs as well as a changing mix of SFGs and quiescent galaxies [ABRIDGED].Comment: 21 pages, 15 figures, 2 tables, resubmitted to ApJ after addressing referee comment

The Growth of Massive Galaxies Since z=2

We study the growth of massive galaxies from z=2 to the present using data from the NEWFIRM Medium Band Survey. The sample is selected at a constant number density of n=2x10^-4 Mpc^-3, so that galaxies at different epochs can be compared in a meaningful way. We show that the stellar mass of galaxies at this number density has increased by a factor of ~2 since z=2, following the relation log(M)=11.45-0.15z. In order to determine at what physical radii this mass growth occurred we construct very deep stacked rest-frame R-band images at redshifts z=0.6, 1.1, 1.6, and 2.0. These image stacks of typically 70-80 galaxies enable us to characterize the stellar distribution to surface brightness limits of ~28.5 mag/arcsec^2. We find that massive galaxies gradually built up their outer regions over the past 10 Gyr. The mass within a radius of r=5 kpc is nearly constant with redshift whereas the mass at 5-75 kpc has increased by a factor of ~4 since z=2. Parameterizing the surface brightness profiles we find that the effective radius and Sersic n parameter evolve as r_e~(1+z)^-1.3 and n~(1+z)^-1.0 respectively. The data demonstrate that massive galaxies have grown mostly inside-out, assembling their extended stellar halos around compact, dense cores with possibly exponential radial density distributions. Comparing the observed mass evolution to the average star formation rates of the galaxies we find that the growth is likely dominated by mergers, as in-situ star formation can only account for ~20% of the mass build-up from z=2 to z=0. The main uncertainties in this study are possible redshift-dependent systematic errors in the total stellar masses and the conversion from light-weighted to mass-weighted radial profiles.Comment: Accepted for publication in the Astrophysical Journal. 26 pages, 13 figures in main tex

Creatinine and myoglobin are poor predictors of anaerobic threshold in colorectal cancer and health

Aims Myoglobin is a haem protein produced in skeletal muscles. Serum concentrations of myoglobin have been proposed as a surrogate marker of muscle mass and function in both cachectic cancer patients and healthy non-cancer individuals. Creatinine, a metabolite of creatine phosphate, an energy store found in skeletal muscle, is produced at a constant rate from skeletal muscle. Urinary and plasma creatinine have been used in clinical practice as indicators of skeletal muscle mass in health and disease. Our study aimed to test the hypothesis that plasma myoglobin and creatinine concentration could accurately predict skeletal muscle mass and aerobic capacity in colorectal cancer (CRC) patients and matched healthy controls and thereby an indicative of aerobic performance. Methods We recruited 47 patients with CRC and matching number of healthy volunteers for this study. All participants had their body composition measured by dual-energy X-ray absorptiometry scan, aerobic capacity measured to anaerobic threshold (AT) by cardiopulmonary exercise testing and filled in objective questionnaires to assess the qualitative functions. This study was carried out in accordance with the Declaration of Helsinki, after approval by the local National Health Service (NHS) Research Ethics Committee. Results Age-matched groups had similar serum myoglobin and creatinine concentrations in spite of differences in their aerobic capacity. AT was significantly lower in the CRC group compared with matched controls (1.18 ± 0.44 vs. 1.41 ± 0.71 L/min; P < 0.01). AT had significant correlation with lean muscle mass (LMM) among these groups, but myoglobin and creatinine had poor correlation with LMM and AT. Conclusions Serum myoglobin is a poor predictor of muscle mass, and serum myoglobin and creatinine concentrations do not predict aerobic performance in CRC patients or healthy matched controls