Economic growth and the dynamic efficiency theory

Esta investigación analiza el crecimiento económico desde la teoría de la eficiencia dinámica, utilizando un indicador global de competitividad y uno de libertad económica global, partiendo de la hipótesis de que mayor libertad económica se traduce en mayor competitividad y crecimiento económico. La eficiencia dinámica sustentada en autores de la economía austriaca pretende explicar cómo el incremento en la rentabilidad y productividad en la producción de bienes y servicios, depende principalmente de la creatividad empresarial. Desde el punto de vista metodológico, el estudio es descriptivo, correlacional y prospectivo, se empleó datos de panel de las 20 economías más grandes del continente americano; también analiza los principales indicadores macroeconómicos, la calidad de las instituciones, salud, educación primaria, infraestructura y el grado de innovación empresarial, correlacionado con variables que miden el nivel de libertad para hacer negocios, presión fiscal, tamaño del gobierno, seguridad jurídica; se mide la competitividad por medio de los factores que determinan la productividad de una economía. Entre los principales resultados se encontró que el índice de libertad económica y el PIB per cápita, muestran una relación causal bidireccional en el sentido de Granger, develando con ello una relación de endogeneidad entre ambas variables. Se demostró el grado de cointegración, causalidad y explicación de la competitividad y la libertad económica con el crecimiento económico.This research analyzes economic growth from the theory of dynamic efficiency, using a global indicator of competitiveness and one of global economic freedom, starting from the hypothesis that greater economic freedom translates into greater competitiveness and economic growth. The dynamic efficiency supported by authors of the Austrian economy aims to explain how the increase in profitability and productivity in the production of goods and services depends mainly on business creativity. From the methodological point of view, the study is descriptive, correlational and prospective, using panel data from the 20 largest economies in the American continent. The study analyzes the main macroeconomic indicators, the quality of institutions, health, primary education, infrastructure and the degree of business innovation, correlated with variables that measure the level of freedom to do business, fiscal pressure, size of government, security Legal, competitiveness is measured through the factors that determine the productivity of an economy. Among the main results, it was found that the index of economic freedom and the GDP per capita show a bidirectional causal relationship in the Granger sense, thus revealing an endogenity relationship between both variables. The degree of cointegration, causality and explanation of competitiveness and economic freedom with economic growth was demonstrated

Challenges for the multilingual Web of Data

Garcia J, Montiel-Ponsoda E, Cimiano P, Gómez-Pérez A, Buitelaar P, McCrae J. Challenges for the multilingual Web of Data. Journal of Web Semantics: Science, Services and Agents on the World Wide Web. 2012;11:63-71

MANUAL PARA PRÁCTICAS DE EXPRESIÓN ESCRITA Y VOCABULARIO EN INGLÉS 3 DENTRO DEL CENTRO DE AUTO-ACCESO (CAA)

MANUAL PARA PRÁCTICAS DE LABORATORIO, TALLER U OTRA ÁREA DE APOYO A LA DOCENCI

Rituximab therapy for chonic and refractory immune thrombocytopenic purpura: a long-term follow-up analysis

The aim of this study was to evaluate the long-term response to rituximab in patients with chronic and refractory immune thrombocytopenic purpura (ITP). Adults with ITP fail to respond to conventional therapies in almost 30% of cases, developing a refractory disease. Rituximab has been successfully used in these patients. We used rituximab at 375 mg/m2, IV, weekly for a total of four doses in 18 adult patients. Complete remission (CR) was considered if the platelet count was >100 × 109/l, partial remission (PR) if platelets were >50 × 109/l, minimal response (MR) if the platelet count was >30 × 109/l and <50 × 109/l, and no response if platelet count remained unchanged. Response was classified as sustained (SR) when it was stable for a minimum of 6 months. Median age was 43.5 years (range, 17 to 70). Median platelet count at baseline was 12.5 × 109/l (range, 3.0 to 26.3). CR was achieved in five patients (28%), PR in five (28%), MR in four (22%), and two patients were classified as therapeutic failures (11%). Two additional patients were lost to follow-up. The median time between rituximab therapy and response was 14 weeks (range, 4 to 32). SR was achieved in 12 patients (67%). There were no severe adverse events during rituximab therapy. During follow-up (median, 26 months; range, 12 to 59), no other immunosuppressive drugs were used. In conclusion, rituximab therapy is effective and safe in adult patients with chronic and refractory ITP. Overall response rate achieved is high, long term, and with no risk of adverse events

Intestinal Dysbiosis and Rheumatoid Arthritis: A Link between Gut Microbiota and the Pathogenesis of Rheumatoid Arthritis

Characterization and understanding of gut microbiota has recently increased representing a wide research eld, especially in autoimmune diseases. Gut microbiota is the major source of microbes which might exert benecial as well as pathogenic effects on human health. Intestinal microbiome’s role as mediator of inammation has only recently emerged. Microbiota has been observed to differ in subjects with early rheumatoid arthritis compared to controls, and this nding has commanded this study as a possible autoimmune process. Studies with intestinal microbiota have shown that rheumatoid arthritis is characterized by an expansion and/or decrease of bacterial groups as compared to controls. In this review, we present evidence linking intestinal dysbiosis with the autoimmune mechanisms involved in the development of rheumatoid arthritis

Analysis of the impact of pronation maneuver in patients on mechanical ventilation with diagnosis of pneumonia by Covid-19 and acute respiratory distress syndrome: Análise do impacto da manobra de pronação em pacientes em ventilação mecânica com diagnóstico de pneumonia por Covid-19 e síndrome do desconforto respiratório agudo

Objective: To analyze the profile of patients on invasive mechanical ventilation with SARS-CoV-2 pneumonia who were pronated and who developed acute respiratory distress syndrome. Methods: Historical cohort study through the analysis of a database containing 282 patients hospitalized in a large university hospital in the city of Porto Alegre, Brazil. The population studied included individuals infected with SARS-CoV-2 and with a clinical course marked by severe pneumonia and, mainly, by acute respiratory distress syndrome, submitted to mechanical ventilation and invasive pronation maneuver. Results: Database analysis showed a high mortality rate for all patient groups and a high case fatality rate, especially in elderly patients and in individuals with active oncologic disease or with chronic kidney disease. Conclusions: The high overall mortality rate, as well as the high lethality, especially in elderly patients and in individuals with active oncologic disease or with chronic kidney disease, suggests that, for certain specific population groups, the prone maneuver is not effective in reducing high. mortality caused by acute respiratory distress syndrome associated with COVID-19

Metabolic Responses of Two Assisted CPR Devices Versus Manual CPR during 1-Person CPR

Prolonged, one-person CPR is exhausting and associated with decayed CPR quality over time. Active compression-decompression-CPR (ACD-CPR) requires the rescuer to actively work during both phases of CPR. We evaluated the metabolic cost of manual CPR (M-CPR), ACD-CPR1, and ACD-CPR2 (with adhesive pad) during a 10-min resuscitation period. We hypothesized that the metabolic cost for the devices would be similar to M-CPR. Twenty (10 female) participants (23.5±3.5y, 165.8±25.6cm, 72.5±12.2kg) completed 3 randomized trials with performance feedback by investigators. Expired air was analyzed for estimations of metabolic cost via indirect calorimetry. Participants rested for 10 minutes before the baseline data collection followed by 10 min of CPR to simulate one-person CPR. Treatment effects were observed for VO2, METS, VCO2, HR, RR, blood lactate, and RPE. No such effect was observed for RQ, SBP, or DBP. VO2 (ml/kgBW/min) was significantly higher with ACD-CPR1 (17.8±1.4) vs. MCPR and ACD-CPR2 (15.9±0.9 and 14.2±1.1, respectively). Metabolic equivalent (MET) was significantly lower with ACD-CPR2 (4.1±0.3) vs. MCPR and ACD-CPR1 (4.7±0.3 and 5.1±0.4, respectively). All three groups’ blood lactate data differed significantly with ACD-CPR1 \u3e M-CPR \u3e ACD-CPR2. The RR required by the ACD-CPR1 during a 10 min CPR simulation is significantly higher than the ACD-CPR2 and M-CPR. No group differences were observed for RQ, SBP, or DBP. CPR performance metrics were averaged over the 10-min resuscitation period. RPE was significantly higher following ACD-CPR1 compared to both M-CPR and ACD-CPR2. The metabolic work required by the ACD-CPR2 during 10-min simulated one-person resuscitation (80/min) is far less than the ACD-CPR1. However, the ACD-CPR2 metabolic cost is similar to that of M-CPR, despite the latter method’s higher rate of compressions (110/min) and passive decompressions