Creación de una empresa de neurorehabilitación.

Administración y Dirección de Empresa

La Activación del Proyecto de Vida. Un acercamiento a la realidad de las personas usuarias y profesionales de las Unidades de Convivencia de San Juan de Dios (Palencia)

La esperanza de vida es uno de los factores estudiados a la hora de analizar el desarrollo de una sociedad. En la actualidad, las políticas sociales, económicas y sanitarias se están adaptando a la sociedad en la que vivimos, una sociedad envejecida. Las personas mayores presentan una serie de características y particularidades sobre las cuales hay que intervenir de forma específica, a través de planes, programas y/o recursos y servicios adaptados a ello. A su vez, es importante tener en cuenta que, dentro de este gran grupo, surgen subgrupos como son las personas mayores con discapacidad y/o enfermedad mental, quienes en ocasiones requieren de su ingreso en recursos como son las Unidades de Convivencia pertenecientes al Centro Asistencial San Juan de Dios de Palencia, lugar donde se contextualiza el presente análisis. La Junta de Castilla y León propone un cambio de paradigma a través del Modelo “En Mi Casa” y La Activación del Proyecto de Vida, estrategias que apuestan por un nuevo modelo de derechos, donde toda intervención gire sobre el principio de autodeterminación de las personas usuarias. En este trabajo se analiza la situación de los usuarios/as y su calidad de vida a través de una triangulación concurrente, metodología empleada para el presente análisis.Departamento de Sociología y Trabajo SocialMáster en Formación e Intervención Sociocomunitari

G2C2 - IV: A novel approach to study the radial distributions of multiple populations in Galactic globular clusters

We use the HB morphology of 48 Galactic GCs to study the radial distributions of the different stellar populations known to exist in globular clusters. Assuming that the (extremely) blue HB stars correspond to stars enriched in Helium and light elements, we compare the radial distributions of stars selected according to colour on the HB to trace the distribution of the secondary stellar populations in globular clusters. Unlike other cases, our data show that the populations are well mixed in 80% of the cases studied. This provides some constraints on the mechanisms proposed to pollute the interstellar medium in young globular clusters.Comment: 8 pages, 6 figures. The complete table of the KS statistics and figures for all the sample clusters showing the cumulative radial distributions can be found in the online appendix. Accepted for publication in MNRA

Petrological Study as a Tool to Evaluate the Degradation of Speleothems in Touristic Caves, Castafiar de Ibor Cave, Caceres, Spain

In Castafiar cave the surface of most of the speleothems present dissolution and corrosion features. In touristic caves, this process has usually been related to the acidification of the atmospheric moisture caused by C02 from the breath of visitors. However, in Castafiar cave the process of corrosion has been also observed in rooms that are not visited by tourists. Petrological studies were carried out in the speleothems affected by surface corrosion in Castafiar cave. The results indicate that this process occurs not only at present time, but over a period of thousands of years, as evidenced by the presence of corrosion lines inside and on the surface of the speleothems. All this and the fact that Castafiar cave recovers very quickly from changes in the environmental parameters, indicates that the dissolution-corrosion process is slow and hence it is not related to the presence of visitors

Micritización de espeleotemas en ambiente meteórico vadoso (Cueva de Castañar de Ibor, Cáceres)

The aragonite and calcite speleothems of the Castañar de Ibor Cave show white and matt coatings that formed by micritization and dissolution of the initial crystals. These processes are also recognised in the inner part of the speleothems. Either in the inner or outher parts the result is the lost of brightness and transparency of the speleothems. Petrographically these coatings are seen as lines of micrite liked to dissolution processes that probably occurred because of the circulation of undersaturated fluids within the cave. At the moment no organic structures have been recognised in relation to the micritizated areas, indicating very probably that the process was inorganically driven

La cueva está viva y es un laboratorio natural

Peer reviewe

The Synthetic Cannabinoid URB447 Exerts Antitumor and Antimetastatic Effect in Melanoma and Colon Cancer

The endocannabinoid system is widespread through the body and carries out a wide variety of functions. However, its involvement in other pathologies, such as cancer, still needs further attention. We aim to investigate the role of CB2 receptor during melanoma and colorectal cancer (CRC) aggressiveness and metastatic growth in the liver. We used the synthetic cannabinoid URB447, a known CB2 agonist and CB1 antagonist drug, and studied prometastatic ability of mouse B16 melanoma and MCA38 CRC cells, by means of proliferation, apoptosis, cell cycle, migration and matrix degradation in vitro upon URB447 treatment. We reported a dose-dependent viability decrease in both tumor types. This result is partly mediated by apoptotic cell death and cell cycle arrest in G1/G0 phase, as observed through flow cytometry. Melanoma and CRC cell migration was affected in a dose-dependent fashion as observed through scratch assay, whereas the secretion of matrix degrading proteins metalloprotease 2 (MMP2) and 9 (MMP9) in tumor cells did not significantly change. Moreover, daily treatment of tumor bearing mice with URB447 decreased the development of liver metastasis in a melanoma model in vivo. This proof of concept study points out to the synthetic cannabinoid URB447 as a potential candidate for deeper studies to confirm its potential as antitumor therapy and liver metastasis treatment for CRC and melanoma.This research was funded by EITB Maratoia-BIOEF (BIO18/IC/003), and the Spanish Ministry of Science and Innovation (MINECOR20/P66/AEI/10.13039/501100011033)

Reportaje multimedia. Una mirada social al estigma de las enfermedades mentales

Alrededor de 450 millones de personas padecen un trastorno mental en todo el mundo. Una cifra que irá en aumento en los próximos años, puesto que la Organización Mundial de la Salud (OMS) alerta del déficit en salud mental a nivel global, y advierte de que menos de la mitad de las personas que sufren algún trastorno mental recibe atención médica. Las cuatro causas principales de discapacidad entre las personas mayores de 5 años corresponden a trastornos mentales, siendo la depresión la primera causa por enfermedad. Aunque se han logrado grandes avances en la comprensión y el tratamiento de las enfermedades mentales, el estigma que las rodea aún persiste. Bajo el titular Deconstruyéndonos, se presenta un reportaje multimedia donde, se ha dado voz a enfermedades como la ansiedad, la depresión, la esquizofrenia y la bipolaridad, trastornos que afectan a más de un 10% de toda la población mundial, a través de diferentes historias de vida que necesitan ser escuchadas. Este TGF tiene como objetivo romper con los estigmas asociados a las enfermedades mentales y acabar con la desinformación existente en torno a la salud mental, a través de la elaboración de diferentes elementos como entrevistas audiovisuales, infografías, encuestas, audios y declaraciones de expertosAround 450 million people suffer from a mental disorder worldwide. A figure that will increase in the coming years, since the World Health Organization (WHO) has already warned of the mental health deficit on a global scale, as less than half of the people suffering from a mental disorder receive medical care. The four leading causes of disability among people over 5 years of age are mental disorders, being depression the main reason of disability due to illness. Although great advances have been reached in the understanding and the treatment of mental illnesses, the stigma surrounding them persists. Under the headline Deconstructing Us, diseases such as anxiety, depression, schizophrenia and bipolar, disorders, which affect more than 10% of the world's population, have been given a voice through different life stories that need to be heard. This multimedia report aims to break up with the stigmas related to mental illnesses and to put an end to the existing misinformation about mental health, through the elaboration of different elements such as audiovisual interviews, infographics, surveys, audios and experts claims.Departamento de Historia Moderna, Contemporánea y de América, Periodismo y Comunicación Audiovisual y PublicidadGrado en Periodism

Ontogeny versus environmental forcing off the Southwest Atlantic Ocean: Nutritional condition of Fuegian sprat (Sprattus fuegensis) early stages

The Fuegian sprat, Sprattus fuegensis, plays a key trophic role in the Southwest Atlantic Ocean. Growth and survival of small pelagic fishes like sprat are strongly affected by environmental variability and can determine recruitment success. We estimated the nucleic acid composition and assessed with a standardized RNA/DNA index (sRD) the nutritional condition of 273 larvae, metamorphosing, and juvenile Fuegian sprat from two environmentally distinct habitats: the waters off Tierra del Fuego (TDF) and the Marine Protected Area Namuncurá/Burdwood Bank (MPAN/BB). A similar ontogenetic pattern, in which nucleic acid concentrations decreased and sRD increased with increasing standard length (SL) among larval stages was observed in both habitats. A higher percentage of preflexion larvae were under the sRD threshold for growth and optimal growth performance, with sRD values being significantly higher in TDF. Postflexion larvae in both habitats showed maximum sRD values, suggesting that both habitats are suitable nursery grounds. In contrast, metamorphosing and juvenile sprat (only captured in TDF) had consistently low nucleic acid concentrations and sRD values despite increasing SL. Environmental forcing (temperature, salinity, and station depth) was assessed over size-corrected larval sRD. The best model included a negative response to station depth, and the effect of processes associated with this factor are discussed. Although further analyses are needed to reveal underlying dynamics determining early development, these results comprise a baseline for future monitoring approaches on Fuegian sprat life traits and factors affecting their recruitment in this region.Fil: García Alonso, Virginia Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Biodiversidad y Biología Experimental y Aplicada. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Biodiversidad y Biología Experimental y Aplicada; ArgentinaFil: Diaz, Marina Vera. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Biodiversidad y Biología Experimental; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones Marinas y Costeras. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales. Instituto de Investigaciones Marinas y Costeras; ArgentinaFil: Pajaro, Marcelo. Instituto Nacional de Investigaciones y Desarrollo Pesquero; ArgentinaFil: Capitanio, Fabiana Lia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Biodiversidad y Biología Experimental y Aplicada. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Biodiversidad y Biología Experimental y Aplicada; Argentin

Growing Up Down South: Spatial and Temporal Variability in Early Growth of Fuegian Sprat Sprattus fuegensis From the Southwest Atlantic Ocean

The Fuegian sprat Sprattus fuegensis represents one of the most important pelagic resources in the Southwest Atlantic Ocean (SWAO), exerting a crucial ecological role as an intermediary link in Patagonian food webs. Otolith microstructure of 217 age-0 sprats were analyzed aiming to characterize growth patterns and possible environmental effects over them. Samples were gathered during three oceanographic surveys (spring 2014; autumns 2016, 2017) in Tierra del Fuego (TDF) and the Marine Protected Area Namuncurá-Burdwood Bank (MPAN-BB), the first Argentinian open-sea marine protected area. Daily growths (DG) of larvae and post-larvae were estimated by individually modeling size and otolith radius relationships through back-calculation procedures using potential and linear functions, respectively. Increment widths (IW) and DG values and trajectories were assessed for older sprats (i.e., survivors) sampled in the autumn surveys considering the habitat, year sampled and sprats’ hatching seasons, and were additionally evaluated in relation to sea-surface temperature (SST). IW and DG trajectories differed primarily according to the habitat sampled and sprats’ hatching seasons. Overall, strong coupling was detected between IW and DG trajectories with SST in both habitats. However, statistical assessment on particular comparisons showed that this general trend is not strictly invariant. Even though several results pinpointed a positive correlation between IW and DG with SST, the highest DG were estimated for summer- and autumn-born sprats sampled in 2016 in the MPAN-BB, period and habitat with the lowest SST values. These results unveil a complex relationship between spatial and temporal variability during early growth of Fuegian sprats, supplying relevant information that could be used in the creation of adequate ecosystem based management strategies in the SWAO.Fil: García Alonso, Virginia Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Biodiversidad y Biología Experimental y Aplicada. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Biodiversidad y Biología Experimental y Aplicada; ArgentinaFil: Brown, Daniel Roberto. Instituto Nacional de Investigaciones y Desarrollo Pesquero; ArgentinaFil: Pájaro, Marcelo. Instituto Nacional de Investigaciones y Desarrollo Pesquero; ArgentinaFil: Capitanio, Fabiana Lia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Biodiversidad y Biología Experimental y Aplicada. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Biodiversidad y Biología Experimental y Aplicada; Argentin