9 research outputs found
Diagnosis and treatment in chronic pancreatitis: an international survey and case vignette study
- Author
- Abiola So
- Aghdassi Aa
- Altonbary Ay
- Andersson R
- Andrianov A
- Anten Mp
- Antonucci A
- Archibugi L
- Ariffin Ac
- Awajdarip Mu
- Azam M
- Balzano G
- Barbu St
- Barreto Sg
- Bedin
- Beilman G
- Berger Z
- Beristain Hernandez Jl
- Berrevoet F
- Bertrand C
- Besselink
- Bettschart V
- Bhalerao Ss
- Boadas J
- Boermeester
- Bollen
- Bong Jj
- Bora D
- Boraschi P
- Bouali R
- Braat H
- Bradley EL 3rd
- Bruno
- Carter R
- Casadei R
- Chang Yt
- Chapa Azuela O
- Chinthakindi M
- Chooklin S
- Coker A
- Conneely Jb
- Cosen Binker L
- Crippa S
- Czak\uf3 L
- de Madaria E
- de Resende Ap
- Deeprasertvit A
- Del Chiaro M
- Desai R
- Donati M
- Dumitrascu T
- Egorov V
- Egorov V
- Ermolaev I
- Erwan B
- Falconi M
- Fedaruk A
- Figueras J
- Fink Ma
- Fockens
- Freeman Ml
- French J
- Frossard Jl
- Frulloni Luca
- Gaia E
- Galeev S
- Garc\ueda Cano J
- Gardner Tb
- Gouma Dj
- Gress Fg
- Guillermo Ead
- Gy\uf6keres T
- Habbe N
- Hackert T
- Han S
- Hjalmar C
- Hlinnik A
- Horvath M
- I\u307nce At
- Ibrahim Mma
- Issa
- Ivanecz A
- Johnson C
- Johnstone M
- Joshi R
- Jovani M
- Juan \uc1
- Kacar S
- Kawabata Y
- Keith Rg
- Kelemen D
- Kimura Y
- Klaase Jm
- Knowles B
- Kostov Dv
- Kuiken S
- Kumar A
- L\ue9vy P
- Lai Pb
- Lara Lf
- Layer P
- Lazuchiewicz Kot M
- Lee Jk
- Lemmers A
- Li Zf
- Lohr M
- Louren\ue7o Lc
- Lykoudis P
- Mahir G
- Malecka Panas E
- Malleo Giuseppe
- Manzelli A
- Marangoni G
- Marc G
- Marco J
- Marja A
- Marra Lopez C
- Marsteller I
- Mart\uedn Rj
- Mart\uednez Moneo E
- Masamune A
- Mayerle J
- Meier Pn
- Meining A
- Melki Z
- Modi S
- Molinari M
- Moody Fg
- Morandi E
- Morioka Cy
- Morris Stiff G
- Mosquera Ja
- Muscarella P. 2nd
- Nakache R
- Napoleon B
- Nealon Wh
- Neri V
- Nikfarjam M
- Oana B
- Omoshoro Jones Jao
- Oppong K
- Orloff Sl
- Oruc N
- Pagano N
- Palermo J. j.
- Papachristou G
- Park W
- Partecke Li
- Paul
- Pereira Pnvr
- Pezzilli R
- Plaudis H
- Pokrotnieks J
- Prifti S
- Rabotyagova Y
- Ramesh H
- Raptis Da
- Rauws Eaj
- Rimbas M
- Rummo O
- Ryska M
- Saatov Z
- Sabu Kg
- Saito T
- Schmitt M
- Schoefl R
- Schwartz Mp
- Shcherba A
- Shcherba A
- Shetty S
- Siatkouski A
- Sikora Ss
- Singh Vk
- Smith Jp
- Smith Kd
- Soreide K
- Sousa Silva D
- Spanier Bwm
- Steer M
- Sulpice L
- Takeyama Y
- Talukdar R
- Thomas L
- Tihanyi B
- Tsoulfas G
- Valeri S
- van der Schaar P
- van Dullemen Hm
- van Geenen E
- van Lander A
- Van Santvoort
- Vasavada B
- Velayutham V
- Venneman Ng
- Verdonk Rc
- Vitali F
- Vladimir V
- Vrochides D
- Wallstabe I
- Wilcox Cm
- Winiarski M
- Yama
- Yasuda T
- Yeaton P
- Yu Yd
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2017
- Field of study
Background: The aim of the study was to evaluate the current opinion and clinical decision-making process of international pancreatologists, and to systematically identify key study questions regarding the diagnosis and treatment of chronic pancreatitis (CP) for future research.Methods: An online survey, including questions regarding the diagnosis and treatment of CP and several controversial clinical case vignettes, was send by e-mail to members of various international pancreatic associations: IHPBA, APA, EPC, ESGE and DPSG.Results: A total of 288 pancreatologists, 56% surgeons and 44% gastroenterologists, from at least 47 countries, participated in the survey. About half (48%) of the specialists used a classification tool for the diagnosis of CP, including the Mayo Clinic (28%), Mannheim (25%), or Buchler (25%) tools. Overall, CT was the preferred imaging modality for evaluation of an enlarged pancreatic head (59%), pseudocyst (55%), calcifications (75%), and peripancreatic fat infiltration (68%). MRI was preferred for assessment of main pancreatic duct (MPD) abnormalities (60%). Total pancreatectomy with auto-islet transplantation was the preferred treatment in patients with parenchymal calcifications without MPD abnormalities and in patients with refractory pain despite maximal medical, endoscopic, and surgical treatment. In patients with an enlarged pancreatic head, 58% preferred initial surgery (PPPD) versus 42% initial endoscopy. In patients with a dilated MPD and intraductal stones 56% preferred initial endoscopic +/- ESWL treatment and 29% preferred initial surgical treatment.Conclusion: Worldwide, clinical decision-making in CP is largely based on local expertise, beliefs and disbeliefs. Further development of evidence-based guidelines based on well designed (randomized) studies is strongly encouraged
Outcomes from elective colorectal cancer surgery during the SARS‐CoV‐2 pandemic
- Author
- 6\u11f\ufcc\ufc H
- 6fner D
- 6hlberger L
- \u106oza I
- \uc2ngelo M
- \uc4lg\ue5 A
- \uc7elebi F
- \uc7olak E
- Aawsaj Y
- Abad Gurumeta A
- Abad\u2010Motos A
- Abate E
- Abbott D
- Abdalla M
- Abdeldayem H
- Abdelkader Salama I
- Abdelkarim M
- Abdur\u2010Rahman L
- Abel MK
- Aboelkassem Ibrahim A
- Abou Chaar MK
- Abou Chaar Mohamad K.
- Abreu da Silva A
- Abubakar A
- Acebes Garc\ueda F
- Achalandabaso Boira M
- Acher A
- Acrich E
- Adamina M
- Adamina Michel
- Ademuyiwa Adesoji O
- Aderombi A
- Adeyeye A
- Adiamah A
- Afonso J
- Agapov M
- Agarwal Arnav
- Aghayeva A
- Agilinko J
- Agnes A
- Agostini C
- Agresta F
- Aguado H
- Aguilar Gonzalez M
- Aguilera Lorena Maria
- Ahmed Z
- Ahmeidat A
- Ahn JH
- Aiken T
- Aim\ue9 A
- Akalin M
- Akaydin E
- Akhtar MA
- Akhter Rahman MM
- Akin E
- Al Abdallah M
- Al Awwad S
- Al Habes H
- Al Maadany FS
- AL Sayed M
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- Alaa S
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- Alawneh F
- Albertsmeier M
- Albertsmeiers Markus
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- Alderson Derek
- Aldokali N
- Aleksi\u107 L
- Alemanno G
- Alfieri S
- Alghamdi M
- Alhamed A
- Alharthi M
- Alhassan N
- Ali Adil AK
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- Alurralde C
- Alvarez E
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- Amaral MJ
- Amin Sahid N
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- Zourntou S
- Zubaidi AM
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2020
- Field of study
Aim
This study aimed to describe the change in surgical practice and the impact of SARS-CoV-2 on mortality after surgical resection of colorectal cancer during the initial phases of the SARS-CoV-2 pandemic.
Method
This was an international cohort study of patients undergoing elective resection of colon or rectal cancer without preoperative suspicion of SARS-CoV-2. Centres entered data from their first recorded case of COVID-19 until 19 April 2020. The primary outcome was 30-day mortality. Secondary outcomes included anastomotic leak, postoperative SARS-CoV-2 and a comparison with prepandemic European Society of Coloproctology cohort data.
Results
From 2073 patients in 40 countries, 1.3% (27/2073) had a defunctioning stoma and 3.0% (63/2073) had an end stoma instead of an anastomosis only. Thirty-day mortality was 1.8% (38/2073), the incidence of postoperative SARS-CoV-2 was 3.8% (78/2073) and the anastomotic leak rate was 4.9% (86/1738). Mortality was lowest in patients without a leak or SARS-CoV-2 (14/1601, 0.9%) and highest in patients with both a leak and SARS-CoV-2 (5/13, 38.5%). Mortality was independently associated with anastomotic leak (adjusted odds ratio 6.01, 95% confidence interval 2.58–14.06), postoperative SARS-CoV-2 (16.90, 7.86–36.38), male sex (2.46, 1.01–5.93), age >70 years (2.87, 1.32–6.20) and advanced cancer stage (3.43, 1.16–10.21). Compared with prepandemic data, there were fewer anastomotic leaks (4.9% versus 7.7%) and an overall shorter length of stay (6 versus 7 days) but higher mortality (1.7% versus 1.1%).
Conclusion
Surgeons need to further mitigate against both SARS-CoV-2 and anastomotic leak when offering surgery during current and future COVID-19 waves based on patient, operative and organizational risks
Cardiovascular disease, chronic kidney disease, and diabetes mortality burden of cardiometabolic risk factors from 1980 to 2010: a comparative risk assessment.
- Author
- 6nal AE
- Aamodt G
- Abdeen Z
- Abdella NA
- Addo J
- Aekplakorn W
- Afifi MM
- Agabiti-Rosei E
- Agyemang C
- Al-Nsour M
- Al-Nuaim AR
- Ali MK
- Ali MM
- Ambady R
- Aro P
- Azizi F
- Babu BV
- Bahalim AN
- Barbagallo CM
- Barbieri MA
- Barcel\uf3 A
- Barreto SM
- Barros H
- Bautista LE
- Benetos A
- Bj\uf6rkelund C
- Bjerregaard P
- Bo S
- Bobak M
- Bonora E
- Botana MA
- Bovet P
- Breckenkamp J
- Breteler MM
- Broda G
- Brown IJ
- Bursztyn M
- C\uedfkov\ue1 R
- Campos H
- Cappuccio FP
- Capuano V
- Carnahan E
- Carvajal RG
- Casiglia E
- Castellano M
- Castetbon K
- Cea L
- Chang CJ
- Chaouki N
- Chatterji S
- Chen CJ
- Chen Z
- Choi JS
- Chua L
- Cobiac LJ
- Cooper RS
- Corsi AM
- Costanza MC
- Cowan MJ
- Craig CL
- Danaei G
- Dankner RS
- Dastgiri S
- de Le\uf3n AC
- Delgado E
- Di Angelantonio E
- Dinc G
- Doi Y
- Dong GH
- Dorsi E
- Dragano N
- Drewnowski A
- Eggertsen R
- Elliott P
- Engeland A
- Erem C
- Esteghamati A
- Ezzati M
- Fall CH
- Fan JG
- Farzadfar F
- Ferreccio C
- Fezeu L
- Finucane MM
- Firmo JO
- Florez HJ
- Forn\ue9s NS
- Fowkes FG
- Franceschini G
- Frisk F
- Frisman GH
- Fuchs FD
- Fuller EL
- G\uf3mez LF
- Getz L
- Giampaoli S
- Gomez-Zumaquero JM
- Graff-Iversen S
- Grant JF
- Gulliford MC
- Gupta PC
- Gupta R
- Gureje O
- Gutierrez HR
- Hansen TW
- Hata J
- He J
- Heim N
- Heinrich J
- Hemmingsson T
- Hennis A
- Herman WH
- Herrera VM
- Ho S
- Holdsworth M
- Hoorn SV
- Hopman WM
- Hussain A
- Husseini A
- Ibrahim MM
- Ikeda N
- Jacobsen BK
- Jaddou HY
- Jafar TH
- Janghorbani M
- Jasienska G
- Joffres MR
- Jonas JB
- Kadiki OA
- Kalter-Leibovici O
- Kamadjeu RM
- Kaptoge S
- Karalis I
- Kastarinen MJ
- Katz J
- Keinan-Boker L
- Kelly P
- Khalilzadeh O
- Khang YH
- Kiechl S
- Kim KW
- Kiyohara Y
- Kobayashi J
- Krause MP
- Kub\uednov\ue1 R
- Kurjata P
- Kusuma YS
- L\ue9vy-Marchal C
- Lam TH
- Langhammer A
- Lawes CM
- Le C
- Lee J
- Lewington S
- Li Y
- Li Y
- Lim SS
- Lim TO
- Lin CC
- Lin HH
- Lin JK
- Lin X
- Lind L
- Lissner L
- Liu X
- Lopez-Jaramillo P
- Lorbeer R
- Lu Y
- Ma G
- Ma S
- Maci\ue0 F
- MacLean DR
- Maggi S
- Magliano DJ
- Makdisse M
- Mancia G
- Mannami T
- Marques-Vidal P
- Mbanya JC
- McFarlane-Anderson N
- Miccoli R
- Miettola J
- Minh HV
- Miquel JF
- Miranda JJ
- Mohamed MK
- Mohan V
- Mohanna S
- Mokdad A
- Mollentze WF
- Morales DD
- Morgan K
- Mozaffarian D
- Muiesan LM
- Muntoni S
- Nabipour I
- Nakagami T
- Nangia V
- Nemesure B
- Neovius M
- Nerhus KA
- Nervi F
- Neuhauser H
- Nguyen M
- Ninomiya T
- Noale M
- Oh SW
- Ohkubo T
- Olivieri O
- Onat A
- Or\uf3stegui M
- Ouedraogo H
- P\ue9rez C
- P\ue9rez-Fern\ue1ndez R
- Pan WH
- Panagiotakos DB
- Panza F
- Park Y
- Passos VM
- Pednekar MS
- Pelizzari PM
- Peres MA
- Phua HP
- Pichardo R
- Pistelli F
- Plans P
- Polakowska M
- Poulter N
- Prabhakaran D
- Qiao Q
- Rafiei M
- Rahim HF
- Raitakari OT
- Ramos LR
- Rampal L
- Rampal S
- Rao M
- Rasmussen F
- Reddy KK
- Redon J
- Revilla L
- Reyes-Garc\ueda V
- Riley LM
- Roaeid RB
- Robinson CA
- Rodriguez-Artalejo F
- Rojas-Martinez R
- Ronkainen K
- Rosero-Bixby L
- Roth GA
- S\ue1nchez JR
- S\uf6derberg S
- Sachdev HS
- Salinas CA
- Sanisoglu SY
- Sans S
- Sarraf-Zadegan N
- Scazufca M
- Schaan BD
- Schapochnik N
- Schelleman H
- Schneider IJ
- Schooling CM
- Schwarz B
- Sekuri C
- Sereday MS
- Serra-Majem L
- Shaw J
- Shera AS
- Shi Z
- Shiri R
- Shu XO
- Silva DA
- Silva E
- Simons LA
- Singh GM
- Smith M
- Soebardi S
- Solfrizzi V
- Sonestedt E
- Soysal A
- Stattin P
- Stein AD
- Stergiou GS
- Stessman J
- Stevens GA
- Sudo A
- Suka M
- Sundh V
- Sundquist K
- Sundstr\uf6m J
- Swai AB
- Tai ES
- Tambs K
- Tesfaye F
- Thomas GN
- Thorogood M
- Tilvis RS
- Tobias M
- Torheim LE
- Trenkwalder P
- Tuomilehto JO
- Tur JA
- Tzourio C
- Uhernik AI
- Ukoli FA
- Unwin N
- Vanderpump MP
- Varo JJ
- Veier\uf8d MB
- Vel\ue1squez-Mel\ue9ndez G
- Verschuren M
- Viet L
- Villalpando S
- Vioque J
- Vollenweider P
- Volpato S
- Wang N
- Wang YX
- Ward M
- Ward M.
- Waspadji S
- Welin LX
- Whitlock G
- Wilhelmsen L
- Willeit J
- Woodward M
- Wormser D
- Xavier AJ
- Xu F
- Xu L
- Yamamoto A
- Yang G
- Yang X
- Yeh LC
- Yoon JS
- You Q
- Yu Z
- Zhang J
- Zhang L
- Zheng W
- Zhou M
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2014
- Field of study
Background: High blood pressure, blood glucose, serum cholesterol, and BMI are risk factors for cardiovascular diseases and some of these factors also increase the risk of chronic kidney disease and diabetes. We estimated mortality from cardiovascular diseases, chronic kidney disease, and diabetes that was attributable to these four cardiometabolic risk factors for all countries and regions from 1980 to 2010.
Methods: We used data for exposure to risk factors by country, age group, and sex from pooled analyses of populationbased health surveys. We obtained relative risks for the eff ects of risk factors on cause-specific mortality from metaanalyses of large prospective studies. We calculated the population attributable fractions for- each risk factor alone,
and for the combination of all risk factors, accounting for multicausality and for mediation of the eff ects of BMI by the other three risks. We calculated attributable deaths by multiplying the cause-specifi c population attributable fractions by the number of disease-specifi c deaths. We obtained cause-specifi c mortality from the Global Burden of
Diseases, Injuries, and Risk Factors 2010 Study. We propagated the uncertainties of all the inputs to the fi nal estimates.
Findings: In 2010, high blood pressure was the leading risk factor for deaths due to cardiovascular diseases, chronic kidney disease, and diabetes in every region, causing more than 40% of worldwide deaths from these diseases; high BMI and glucose were each responsible for about 15% of deaths, and high cholesterol for more than 10%. After
accounting for multicausality, 63% (10\ub78 million deaths, 95% CI 10\ub71\u201311\ub75) of deaths from these diseases in 2010 were attributable to the combined eff ect of these four metabolic risk factors, compared with 67% (7\ub71 million deaths, 6\ub76\u20137\ub76) in 1980. The mortality burden of high BMI and glucose nearly doubled from 1980 to 2010. At the country level, age-standardised death rates from these diseases attributable to the combined eff ects of these four risk factors surpassed 925 deaths per 100 000 for men in Belarus, Kazakhstan, and Mongolia, but were less than 130 deaths per 100 000 for women and less than 200 for men in some high-income countries including Australia, Canada, France, Japan, the Netherlands, Singapore, South Korea, and Spain.
Interpretation: The salient features of the cardiometabolic disease and risk factor epidemic at the beginning of the 21st century are high blood pressure and an increasing eff ect of obesity and diabetes. The mortality burden
of cardiometabolic risk factors has shifted from high-income to low-income and middle-income countries. Lowering cardiometabolic risks through dietary, behavioural, and pharmacological interventions should be a part of the global response to non-communicable diseases
Suicidal ideation in a European Huntington's disease population
- Author
- 't Hart EP
- 8kland E
- \u160a\u161inkov\ue1 P
- \uc5man J
- Aaserud O
- Abbruzzese G
- Akhtar S
- Albanese A
- Alberti S
- Alberti S
- Alegre J
- Allain P
- Alonso-Frech F
- Amico E
- Amico E
- Ammendola S
- Ammendola S
- Andrade C
- Andrews T
- Andrews T
- Andrich J
- Anna A.M. Hubers
- Antczak J
- Armstrong R
- Arques PN
- Arran N
- Artiga MJ
- Avarvarei LD
- Azulay JP
- B\ue1rcenas AH
- B\ufcrk K
- Babiloni B
- Banaszkiewicz K
- Bandmann O
- Barbera MA
- Barker RA
- Barrero F
- Barth K
- Barth K
- Bas J
- Bascu\uf1ana M
- Bastida AM
- Bek J
- Bellonet M
- Bentivoglio AR
- Bentivoglio AR
- Bentivoglio AR
- Berrissoul H
- Bertini E
- Betz S
- Bisson J
- Biunno I
- Bj\uf8rgo K
- Blaszcyk M
- Bo\u107wi\u144ska D
- Boczarska-Jedynak M
- Boelmans K
- Bohlen S
- Bolwijn J
- Bonelli RM
- Bonelli RM
- Bonelli RM
- Boogaerts A
- Bos R
- Bos R
- Bosca M
- Bosredon C
- Bost M
- Bradbury A
- Braunwarth EM
- Brockie P
- Brugada FC
- Brugger F
- Bruno S
- Bryl A
- Buck A
- Buratti L
- Burguera JA
- Burgunder JM
- Burgunder JM
- Burn J
- Burrows L
- Busquets N
- Busse M
- Butcher C
- C\ue0rdenas RP
- C\ue1ceres MT
- Cabaret M
- Caldentey JG
- Callaghan J
- Callaghan J
- Callaghan J
- Calopa M
- Calvas F
- Capellari S
- Capetian P
- Carette AS
- Carrillo F
- Carruesco GT
- Casado AG
- Catalli C
- Catalli C
- Catena JL
- Cavaco S
- Cheriet S
- Chiara P
- Chiara P
- Chu C
- Chu E
- Ciach-Wysocka E
- Ciesielska A
- Clayton C
- Clenaghan C
- Coelho M
- Coleman C
- Connemann J
- Constantinescu R
- Cormio C
- Correia-Guedes L
- Correia-Guedes L
- Cortelli P
- Costa C
- Courtin F
- Craufurd D
- Crooks J
- Cubillo PT
- Cubillo PT
- Cubo E
- Curtis A
- D\ue9monet JF
- D\uedez-AjaL\uf3pez C
- da Silva WV
- Dam\ue1sio J
- David Craufurd
- Davidson J
- De Bruycker C
- De Michele G
- de Raedt S
- Debruxelles S
- Dec M
- Decorte E
- Defebvre L
- Defebvre L
- Dekker M
- Delfini M
- Delliaux M
- Delval A
- Descals AM
- Destee A
- Di Giacopo R
- Di Bella D
- Di Donato S
- Di Giacopo R
- Di Maio L
- Di Maria E
- Di Pardo A
- Di Pietro A
- di Poggio MB
- Diercks G
- Dipple H
- Doherty K
- Dose M
- Dougherty A
- Downie L
- Dressler D
- Duch\ue9 C
- Dujardin K
- Dumas EM
- Dunnett S
- Dunnett SB
- Duru C
- Dziadkiewicz A
- Ecker D
- Ecker D
- Edwards M
- Ekwall C
- Elifani F
- Elifani F
- Ellrichmann G
- Elorza MD
- Erik J. Giltay REGISTRY investigators of the European Huntington's Disease Network. Collaborators: Bachoud-L\ue9vi AC
- Erik van Duijn
- Eschenbach C
- Esmaeilzadeh M
- Eusebio A
- Fairtlough H
- Fannemel M
- Fasano A
- Fasano A
- Fasquel V
- Fenollar M
- Ferrandes G
- Ferreira JJ
- Ferreira JJ
- Ferrer PQ
- Fillingham K
- Finisterra AM
- Fisher K
- Flamez A
- Fletcher A
- Fluch\ue8re F
- Fortuna L
- Foster J
- Foustanos I
- Fredlund G
- Freire-Patino D
- Frich J
- Frontali M
- Frontali M
- Fullam R
- Fullam R
- Fullam R
- G. Bernhard Landwehrmeyer
- G\uf6ller ML
- G\uf8rvell P
- Gago M
- Gallantrae D
- Gallassi R
- Ganos C
- Garc\ueda RG
- Garc\ueda Ru\uedz PJ
- Garc\ueda SS
- Garcia AC
- Garcia PM
- Garde MB
- Garrett C
- Gaston I
- Gelderblom H
- Gellera C
- Genitrini S
- Ghelli E
- Gill P
- Ginestroni A
- Godefroy O
- Goerendt I
- Gogol A
- Gohier B
- Goizet C
- Golding C
- Golding C
- Gonz\ue1lez M
- Gonz\ue1lez SG
- Gorospe A
- Gorzkowska A
- Gorzolla H
- Griguoli A
- Griguoli A
- Gu\ue9rid MA
- Guerra MR
- Guerrero R
- Guia DB
- Guidubaldi A
- Guidubaldi A
- Guisasola LM
- Guzman
- H\uf6glund A
- H\uf6lzner E
- H\uf8sterey-Ugander U
- Haider S
- Hamer S
- Hametner EM
- Hametner EM
- Handley O
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- Harding A
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- Harrison D
- Hartikainen P
- Hauge E
- Hayward B
- Hecht K
- Heiberg A
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- Heinicke W
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- Hepperger C
- Hernanz LC
- Herranhof B
- Herrera CD
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- Hoffmann R
- Holas C
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- Horta SM
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- Hugh Rickards
- Hughes A
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- Hussl A
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- Idiago JM
- ielewska AW
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- Jack R
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- Jacopini G
- Jameau L
- Jamieson S
- Jamrozik Z
- Janik P
- Janu\ue1rio C
- Jaremek KB
- Jasinska-Myga B
- Johansson A
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- Johnson L
- Johnstone C
- Jones L
- Jones M
- Jones U
- K\u142odowska-Duda G
- K\ue4rpp\ue4 M
- Kaelin A
- Kajula O
- Kaminska A
- Kaminski B
- Kapfhammer HP
- Kavalier F
- Kazoka M
- Khalil H
- Klemp\ued\u159 J
- Klimberg A
- Kohl Z
- Koivisto SP
- Komati S
- Koppers K
- Koppitz M
- Kosinski CM
- Kraus A
- Krawczyk M
- Kremer HP
- Krysa W
- Krystkowiak P
- Kwiecinski H
- L\uf3pez-Send\uf3n Moreno JL
- Ladurner G
- Lafoucri\ue8re D
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- Laing H
- Lambeck J
- Landwehrmeyer B
- Landwehrmeyer GB
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- Lashwood A
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- Legarda I
- Lemaire MH
- Levey J
- Lewerenz J
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- Leythaeuser G
- Lezius F
- lhagen SE
- Lilek S
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- Llesoy JR
- llmann TI
- Longato N
- Longinus B
- Longthorpe M
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- Loria G
- Loria G
- Loureiro R
- Loutfi G
- M\uf6ller JC
- M\ufchlau M
- M\ufcller C
- M\ufcller N
- M\ufcnchau A
- M\ufctze L
- Maass A
- Magalh\ue3es M
- Maglione V
- Maglione V
- Magnet M
- Majerov\ue1 V
- Mandich P
- Manouvrier S
- Mantaux B
- Manuel J
- Marcel C
- Marchese R
- Marcinkowski J
- Mariotti C
- Mariscal N
- Markova I
- Marquard R
- Mart\uednez IH
- Mart\uednez LM
- Mart\uednez-Descals A
- Martikainen K
- Martinez-Jaurrieta MD
- Martino T
- Martino T
- Martirio M
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- Massano J
- Massarelli M
- Massarelli M
- Massaro F
- Matheson K
- McGill M
- McKenzie S
- Mechi C
- Meireles J
- Mendes T
- Mestre T
- Mestre T
- Middleton J
- Miedzybrodzka Z
- Milkereit E
- Miller J
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- Minster S
- Mir P
- Monza D
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- Moreau LV
- Moreno G
- Morez V
- Morgan K
- Mundler L
- Murphy H
- Musgrave H
- Mustonen A
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- Neleborn-Lingefj\ue4rd L
- Nemeth AH
- Nepper S
- Nielsen JE
- Nielsen MG
- Niess A
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- Nowak M
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- O'Keefe D
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- Olivier A
- Olofsson C
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- Overland T
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- P\ue5lhagen S
- Padieu H
- Paganini M
- Painold A
- Paridi D
- Pariente J
- Parkinson A
- Partington-Jones L
- Patel A
- Paterski L
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- Paucar M
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- Pe\uf1a JC
- Pearson P
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- Sprenger F
- Spruth EJ
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- St\u119pniak I
- St\ue4dtler M
- Staffen W
- Stamm C
- Stattin EL
- Stebler Y
- Steinmetz G
- Stenwak A
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- Stompel D
- Stopford C
- Storch A
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- Su\u142ek A
- Suarez MJ
- Summers F
- Sundblom J
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- Svenningsson P
- Swain R
- Szczudlik A
- Szczygie\u142 E
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- Tacik P
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- Tim\uf3teo \uc2
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- Tommaso M
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- Torres Rodr\uedguez MJ
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- Trender-Gerhard I
- Tuuha K
- Tyvoll H
- Uhrova T
- Ullah J
- Ure A
- Val JL
- Valadas A
- Valentine R
- Valle N
- van den Bogaard SJ
- van Duijn E
- van Hout MS
- van Reijen D
- van Vugt JP
- Vandenberghe W
- Vandenberghe W
- Ventura MF
- Verellen- Dumoulin C
- Verg\ue9 LR
- Vergara MR
- Verny C
- Verstraelen N
- Viladrich CM
- Villanueva C
- Vives B
- Vuillaume I
- W\uf3jcik M
- Wagner C
- Wahlstr\uf6m J
- Wahlstr\uf6m J
- Walleczek AM
- Walsem MR
- Walsem MR
- Wannepain S
- Warner T
- Weber S
- Weert A
- Wehus R
- Weindl A
- Wenning G
- Werner CJ
- Westman L
- Westmoreland L
- Weydt P
- Whaite A
- Wi\u15bniewski B
- Widner H
- Wiklund L
- Wikstr\uf6m B
- Wild E
- Wild S
- Wild S
- Winkelmann J
- Winkler J
- Winnberg E
- Witjes-An\ue9 MN
- Witkowski G
- Wolz M
- Wright A
- Wright A
- Wright J
- Y\ue9benes JG
- Yarduiman P
- Yardumian P
- Yates S
- Yudina E
- Zaremba J
- Zaremba J
- Zdzienicka E
- Ziegler C
- Zielonka D
- Zielonka D
- Zielonka E
- Zieora-Jakutowicz K
- Zimmermann M
- Zinzi P
- Zinzi P
- Zinzi P
- Zittel S
- Zucker B
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2013
- Field of study
Previous studies indicate increased prevalences of suicidal ideation,
suicide attempts, and completed suicide in Huntington's disease (HD) compared
with the general population. This study investigates correlates and predictors of
suicidal ideation in HD.
METHODS: The study cohort consisted of 2106 HD mutation carriers, all
participating in the REGISTRY study of the European Huntington's Disease Network.
Of the 1937 participants without suicidal ideation at baseline, 945 had one or
more follow-up measurements. Participants were assessed for suicidal ideation by
the behavioural subscale of the Unified Huntington's Disease Rating Scale
(UHDRS). Correlates of suicidal ideation were analyzed using logistic regression
analysis and predictors were analyzed using Cox regression analysis.
RESULTS: At baseline, 169 (8.0%) mutation carriers endorsed suicidal ideation.
Disease duration (odds ratio [OR]=0.96; 95% confidence interval [CI]: 0.9-1.0),
anxiety (OR=2.14; 95%CI: 1.4-3.3), aggression (OR=2.41; 95%CI: 1.5-3.8), a
previous suicide attempt (OR=3.95; 95%CI: 2.4-6.6), and a depressed mood
(OR=13.71; 95%CI: 6.7-28.0) were independently correlated to suicidal ideation at
baseline. The 4-year cumulative incidence of suicidal ideation was 9.9%.
Longitudinally, the presence of a depressed mood (hazard ratio [HR]=2.05; 95%CI:
1.1-4.0) and use of benzodiazepines (HR=2.44; 95%CI: 1.2-5.0) at baseline were
independent predictors of incident suicidal ideation, whereas a previous suicide
attempt was not predictive.
LIMITATIONS: As suicidal ideation was assessed by only one item, and participants
were a selection of all HD mutation carriers, the prevalence of suicidal ideation
was likely underestimated.
CONCLUSIONS: Suicidal ideation in HD frequently occurs. Assessment of suicidal
ideation is a priority in mutation carriers with a depressed mood and in those
using benzodiazepines
Body mass index and complications following major gastrointestinal surgery: a prospective, international cohort study and meta-analysis.
- Author
- 6rhalmi J
- 6zkan Bb
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- \u160irok\ue1 M
- \u17debr\ue1k R
- Aarts E
- Abbas Z
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- Abdelgalil R
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- Sukumar S
- Suleman Yn
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- Tay Ay
- Tayeh S
- Taylor F
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- Teh Jw
- Teixeira da Silva M
- Tejero Pintor Fj
- Telfer R
- Temiz C
- Teng V
- Teoh Pj
- Ter Bruggen Ffja
- Ter Horst L
- Ter Weele K
- Thacoor A
- Thakker Ce
- Thakur H
- Tharakan Rg
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- Theodoreson Md
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- Thevathasan Aa
- Thirumal V
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- Thompson Od
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- Tirnaksiz Mb
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- Topham C
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- Trail M
- Traynor Bp
- Trecarten S
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- Trist Aj
- Troia A
- Trompetto M
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- Truss A
- Tsui Ay
- Tulum H
- Tung L
- Turaga S
- Turati L
- Turkmen M
- Turley H
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- Turner Ejh
- Turner J
- Turner L
- Turner M
- Turpan M
- Tutam Dn
- Ucar E
- Uctepe F
- Uittenbogaart M
- Ulkucu A
- Ulusahin M
- Unal Ag
- Ungcharoen N
- Uppal E
- Urquhart A
- Uzun B
- Uzun O
- Uzun S
- Uzunoglu Ec
- Vable T
- Valderrama P\ue9rez A
- Valli A
- Vallve-Bernal M
- Van Bruggen D
- van Dalen Ashm
- van de Ven Awh
- van der Harst E
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- Van der Lubbe M
- van der Pool Aem
- van der Zee C
- Van Dijck Wpm
- van Elst Tr
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- Van Grevenstein Wmu
- Van Heumen Tm
- van Leeuwen Bl
- van Rijckevorsel Vajim
- van Steensel L
- Van Tol Rr
- van Verschuer Vmt
- van Wijnbergen Jwm
- Vanmali P
- Varley R
- Varma D
- Varma N
- Varma Rk
- Varo Mu\uf1oz A
- Vasko P
- Vasquez G
- Vaughan R
- Vazquez-Gonzalez I
- Veenker Cgh
- Vela Polanco Ff
- Vendramin E
- Venn M
- Ventre Cm
- Venturini S
- Verardi L
- Verboeket B
- Verma K
- Verma S
- Vermaas M
- Vernon Ok
- Vi\uf1as-Salas J
- Villarejo Campos P
- Vinci A
- Vithanage Na
- Vivekanantham S
- Vives-Rodriguez E
- Vries Jjm
- Wadanamby S
- Waldron Rm
- Walford Ra
- Wali A
- Wall C
- Walsh Sl
- Wan Jc
- Wang A
- Wang S
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- Ward N
- Ward T
- Warren N
- Warwick Hl
- Watson N
- Watson Rp
- Weaver R
- Webb E
- Weinberg D
- Wells M
- Weston C
- Wetherall N
- Whacha C
- Whatling Ea
- Whewell H
- White A
- White Cj
- White U
- Whitehurst K
- Whitham Rdj
- Whittingham H
- Wiersema R
- Wiezer R
- Wijesekera M
- Wijffels N
- Wijnhoven Bpl
- Wild Jrl
- Wilkinson D
- Willems L
- Willems Yr
- Williams M
- Williams Mr
- Williams P
- Williams Rp
- Wills J
- Wilson H
- Wilson Hcp
- Wilson R
- Wilson T
- Wiltshire Jj
- Winarski A
- Wing Vc
- Wingfield Lr
- Winslow F
- Woin E
- Wong C
- Wong E
- Wong V
- Wood Ad
- Woodcock N
- Woodward H
- Woon E
- Wright A
- Wright Ev
- Wye J
- Wylam D
- Wylie J
- Wynell-Mayow Wm
- Xiao C
- Xu Gx
- Xylas D
- Y\u131gman S
- Yalcin Y
- Yaman S
- Yan A
- Yang T
- Yasar C
- Yates Ja
- Yauw S
- Yavuz G
- Yazkan Z
- Yekenkurul E
- Yener A
- Yeoh Tsl
- Yetiskin E
- Yildirim N
- Yildirim R
- Yildiz S
- Yildiz Ss
- Yildiz T
- Yilmaz I
- Yilmaz M
- Yilmaz S
- Yilmaz T
- Yim N
- Yoganathan S
- Yong Cs
- Yong N
- Yoruk I
- Yousif A
- Yow L
- Yuen R
- Yuksek B
- Yuksek Ma
- Yuksel A
- Yurdaor Ss
- Yurekli Am
- Zaidi R
- Zegeye Mi
- Zengin T
- Zhang Aa
- Zhao J
- Ziff O
- Zigiotto D
- Zijlmans Jl
- Zimmerman D
- Ziprin P
- Zope S
- Zuhair M
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2018
- Field of study
AIM:
Previous studies reported conflicting evidence on the effects of obesity on outcomes after gastrointestinal surgery. The aims of this study were to explore the relationship of obesity with major postoperative complications in an international cohort and to present a meta-analysis of all available prospective data.
METHODS:
This prospective, multicentre study included adults undergoing both elective and emergency gastrointestinal resection, reversal of stoma or formation of stoma. The primary end-point was 30-day major complications (Clavien-Dindo Grades III-V). A systematic search was undertaken for studies assessing the relationship between obesity and major complications after gastrointestinal surgery. Individual patient meta-analysis was used to analyse pooled results.
RESULTS:
This study included 2519 patients across 127 centres, of whom 560 (22.2%) were obese. Unadjusted major complication rates were lower in obese vs normal weight patients (13.0% vs 16.2%, respectively), but this did not reach statistical significance (P = 0.863) on multivariate analysis for patients having surgery for either malignant or benign conditions. Individual patient meta-analysis demonstrated that obese patients undergoing surgery for malignancy were at increased risk of major complications (OR 2.10, 95% CI 1.49-2.96, P < 0.001), whereas obese patients undergoing surgery for benign indications were at decreased risk (OR 0.59, 95% CI 0.46-0.75, P < 0.001) compared to normal weight patients.
CONCLUSIONS:
In our international data, obesity was not found to be associated with major complications following gastrointestinal surgery. Meta-analysis of available prospective data made a novel finding of obesity being associated with different outcomes depending on whether patients were undergoing surgery for benign or malignant disease
Search for a heavy top-quark partner in final states with two leptons with the ATLAS detector at the LHC
- Author
- Aad G
- Abajyan T
- Abbott B
- Abdallah J
- Abdelalim AA
- Abdinov O
- Aben R
- Abi B
- Abolins M
- AbouZeid OS
- Abramowicz H
- Abreu H
- Acerbia E
- Acharya BS
- Adam ER
- Adamczyk L
- Adams DL
- Addy TN
- Adelman J
- Adomeit S
- Adragna P
- Adye T
- Aefsky S
- Aguilar-Saavedra JA
- Agustoni M
- Aharrouche M
- Ahlen SP
- Ahles F
- Ahmad A
- Ahsan M
- Aielli G
- Akdogan T
- Akesson TPA
- Akimoto G
- Akimov AV
- Alam MA
- Alam MS
- Albert J
- Albrand S
- Aleksa M
- Aleksandrov IN
- Alessandria F
- Alexa C
- Alexander G
- Alexandre G
- Alexopoulos T
- Alhroob M
- Aliev M
- Alimonti G
- Alison J
- Allbrooke BMM
- Allport PP
- Allwood-Spiers SE
- Almenar CC
- Almond J
- Aloisio A
- Alon R
- Alonso A
- Alonso F
- Alviggi MG
- Amako K
- Amelung C
- Ammosov VV
- Amorim A
- Amram N
- Anastopoulos C
- Ancu LS
- Andari N
- Andeen T
- Anders CF
- Anders G
- Anderson KJ
- Andreazza A
- Andrei V
- Anduaga XS
- Anger P
- Angerami A
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- Publication venue
- Publication date
- 01/01/2012
- Field of study
Search for squarks and gluinos with the ATLAS detector in final states with jets and missing transverse momentum using s=8 TeV proton-proton collision data
- Author
- Aad G
- Abbott B
- Abdallah J
- Abdinov O
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- Åkesson TPA
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- Ženiš T
- Publication venue
- Springer Verlag
- Publication date
- 01/01/2014
- Field of study
Abstract: A search for squarks and gluinos in final states containing high-pT jets, missing transverse momentum and no electrons or muons is presented. The data were recorded in 2012 by the ATLAS experiment in (formula presented) TeV proton-proton collisions at the Large Hadron Collider, with a total integrated luminosity of 20.3 fb−1. Results are interpreted in a variety of simplified and specific supersymmetry-breaking models assuming that R-parity is conserved and that the lightest neutralino is the lightest supersymmetric particle. An exclusion limit at the 95% confidence level on the mass of the gluino is set at 1330 GeV for a simplified model incorporating only a gluino and the lightest neutralino. For a simplified model involving the strong production of first- and second-generation squarks, squark masses below 850 GeV (440 GeV) are excluded for a massless lightest neutralino, assuming mass degenerate (single light-flavour) squarks. In mSUGRA/CMSSM models with tan β = 30, A0 = −2m0 and μ > 0, squarks and gluinos of equal mass are excluded for masses below 1700 GeV. Additional limits are set for non-universal Higgs mass models with gaugino mediation and for simplified models involving the pair production of gluinos, each decaying to a top squark and a top quark, with the top squark decaying to a charm quark and a neutralino. These limits extend the region of supersymmetric parameter space excluded by previous searches with the ATLAS detector.[Figure not available: see fulltext.
Search for squarks and gluinos with the ATLAS detector in final states with jets and missing transverse momentum using (Formula presented.) TeV proton-proton collision data
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- Yusuff I
- Zabinski B
- Zaidan R
- Zaitsev AM
- Zaman A
- Zambito S
- Zanello L
- Zanzi D
- Zeitnitz C
- Zeman M
- Zemla A
- Zengel K
- Zenin O
- Zerwas D
- Zhang D
- Zhang F
- Zhang H
- Zhang J
- Zhang L
- Zhang X
- Zhang Z
- Zhao Z
- Zhemchugov A
- Zhong J
- Zhou B
- Zhou L
- Zhou N
- Zhu CG
- Zhu H
- Zhu J
- Zhu Y
- Zhuang X
- Zhukov K
- Zibell A
- Zieminska D
- Zimine NI
- Zimmermann C
- Zimmermann R
- Zimmermann S
- Zinonos Z
- Ziolkowski M
- Zobernig G
- Zoccoli A
- zur Nedden M
- Zurzolo G
- Zutshi V
- Zwalinski L
- Åkesson TPA
- Åsman B
- Ženiš T
- Publication venue
- Springer-Verlag Italia s.r.l.
- Publication date
- 01/01/2014
- Field of study
Abstract: A search for squarks and gluinos in final states containing high-pT jets, missing transverse momentum and no electrons or muons is presented. The data were recorded in 2012 by the ATLAS experiment in (Formula presented.) TeV proton-proton collisions at the Large Hadron Collider, with a total integrated luminosity of 20.3 fb−1. Results are interpreted in a variety of simplified and specific supersymmetry-breaking models assuming that R-parity is conserved and that the lightest neutralino is the lightest supersymmetric particle. An exclusion limit at the 95% confidence level on the mass of the gluino is set at 1330 GeV for a simplified model incorporating only a gluino and the lightest neutralino. For a simplified model involving the strong production of first- and second-generation squarks, squark masses below 850 GeV (440 GeV) are excluded for a massless lightest neutralino, assuming mass degenerate (single light-flavour) squarks. In mSUGRA/CMSSM models with tan β = 30, A0 = −2m0 and μ > 0, squarks and gluinos of equal mass are excluded for masses below 1700 GeV. Additional limits are set for non-universal Higgs mass models with gaugino mediation and for simplified models involving the pair production of gluinos, each decaying to a top squark and a top quark, with the top squark decaying to a charm quark and a neutralino. These limits extend the region of supersymmetric parameter space excluded by previous searches with the ATLAS detector.[Figure not available: see fulltext.]
Search for direct production of charginos, neutralinos and sleptons in final states with two leptons and missing transverse momentum in pp collisions at s = 8TeV with the ATLAS detector
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- A Heister
- A Lazopoulos
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- Y. Nagasaka
- Y. Nakahama
- Y. Ninomiya
- Y. Okumura
- Y. Oren
- Y. Qin
- Y. Rozen
- Y. S. Gao
- Y. Sakurai
- Y. Sasaki
- Y. Silver
- Y. Smirnov
- Y. Sugaya
- Y. Suzuki
- Y. Takahashi
- Y. Takubo
- Y. Tayalati
- Y. Unno
- Y. V. Grishkevich
- Y. Wu
- Y. Yamaguchi
- Y. Yamazaki
- Y. Yang
- Y. Yasu
- Y. Zhu
- Yu. A. Tikhonov
- Z. Barnovska
- Z. Czyczula
- Z. D. Greenwood
- Z. Dolezal
- Z. Gecse
- Z. H. Citron
- Z. Hajduk
- Z. Hubacek
- Z. J. Grout
- Z. Kohout
- Z. L. Ren
- Z. Liang
- Z. Marshall
- Z. Rurikova
- Z. V. Krumshteyn
- Z. Vykydal
- Z. Weng
- Z. Yan
- Z. Zhang
- Z. Zhao
- Z. Zinonos
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study