Resultaten en ambities : proef de vooruitgang!

In 2007 namen Ziekenhuis Gelderse Vallei in Ede en de afdeling Humane Voeding van Wageningen University het initiatief tot samenwerking en vormden zij de Alliantie Voeding Gelderse Vallei. De Alliantie Voeding koppelt preventie aan zorg. Voor jong tot oud is voorlichting over gezonde voeding van belang. Effectieve preventie én de integratie van preventie in de zorg levert gezondheidswinst en verhoging van kwaliteit van leven op individueel en populatie niveau. De Alliantie Voeding heeft hiertoe drie programma's opgesteld

Prevalence of overweight in Dutch children with Down syndrome

OBJECTIVE Prevalence of overweight in children is increasing, causing various health problems. This study aims to establish growth references for weight and to assess the prevalence rates of overweight and obesity in a nationwide sample of Dutch children with Down syndrome (DS), taking into account the influence of comorbidity. METHODS In 2009, longitudinal growth data from Dutch children with trisomy 21 who were born after 1982 were retrospectively collected from medical records of 25 Dutch regional specialized DS centers. "Healthy" was defined as not having concomitant disorders or having only a mild congenital heart defect. Weight and BMI references were calculated by using the LMS method, and prevalence rates of overweight and obesity by using cutoff values for BMI as defined by the International Obesity Task Force. Differences in prevalence rates were tested by multilevel logistic regression analyses to adjust for gender and age. RESULTS Growth data of 1596 children with DS were analyzed. Compared with the general Dutch population, healthy children with DS were more often overweight (25.5% vs 13.3% in boys, and 32.0% vs 14.9% in girls) and obese (4.2% vs 1.8%, and 5.1% vs 2.2%, respectively). Prevalence rates of overweight between DS children with or without concomitant disorders did not vary significantly. CONCLUSIONS Dutch children with DS have alarmingly high prevalence rates of overweight and obesity during childhood and adolescence. Health care professionals should be aware of the risk of overweight and obesity in children with DS to prevent complications.Prevention, Population and Disease management (PrePoD

Surgical removal of amyloid-laden lymph nodes: a possible therapeutic approach in a primary systemic AL amyloidosis patient with focal lymphadenopathy

We report a patient with primary systemic AL amyloidosis who suffered from remarkable bilateral cervical lymphadenopathy. Intensive chemotherapies, including two cycles of high-dose melphalan with autologous peripheral blood stem cell transplantation, were insufficiently effective for both the lymphadenopathy and amyloidogenic IgG lambda lambda-type M-protein in serum, but the patient showed complete haematological remission after extensive surgical removal of enlarged lymph nodes that had massive depositions of lambda lambda-type immunoglobulin light chain-derived amyloid. Lymphadenectomy may be a possible therapeutic approach with regard to both cosmetic and haematological aspects in primary systemic AL amyloidosis patients with focal lymphadenopathy.ArticleAMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS. 18(2):79-82 (2011)journal articl

Demographic, clinical and antibody characteristics of patients with digital ulcers in systemic sclerosis: data from the DUO Registry

OBJECTIVES: The Digital Ulcers Outcome (DUO) Registry was designed to describe the clinical and antibody characteristics, disease course and outcomes of patients with digital ulcers associated with systemic sclerosis (SSc). METHODS: The DUO Registry is a European, prospective, multicentre, observational, registry of SSc patients with ongoing digital ulcer disease, irrespective of treatment regimen. Data collected included demographics, SSc duration, SSc subset, internal organ manifestations, autoantibodies, previous and ongoing interventions and complications related to digital ulcers. RESULTS: Up to 19 November 2010 a total of 2439 patients had enrolled into the registry. Most were classified as either limited cutaneous SSc (lcSSc; 52.2%) or diffuse cutaneous SSc (dcSSc; 36.9%). Digital ulcers developed earlier in patients with dcSSc compared with lcSSc. Almost all patients (95.7%) tested positive for antinuclear antibodies, 45.2% for anti-scleroderma-70 and 43.6% for anticentromere antibodies (ACA). The first digital ulcer in the anti-scleroderma-70-positive patient cohort occurred approximately 5 years earlier than the ACA-positive patient group. CONCLUSIONS: This study provides data from a large cohort of SSc patients with a history of digital ulcers. The early occurrence and high frequency of digital ulcer complications are especially seen in patients with dcSSc and/or anti-scleroderma-70 antibodies

Voedselverspilling in de zorg : afvalmetingen in Ziekenhuis Gelderse Vallei geven opmerkelijke resultaten

Metingen in Ziekenhuis Gelderse Vallei hebben aangetoond dat een groot deel van de verstrekte maaltijden in de afvalbak verdwijnt. Het in juni 2012 uitgevoerde onderzoek geeft opmerkelijke resultaten. Zo blijkt bijvoorbeeld dat 30% van al het klaargemaakte voedsel al in de keuken zelf wordt weggegooid. Met de invoering van het maaltijdconcept At Your Request verwacht het ziekenhuis de voedselverspilling te minimaliseren

Resultaten en ambities : proef de vooruitgang!

In 2007 namen Ziekenhuis Gelderse Vallei in Ede en de afdeling Humane Voeding van Wageningen University het initiatief tot samenwerking en vormden zij de Alliantie Voeding Gelderse Vallei. De Alliantie Voeding koppelt preventie aan zorg. Voor jong tot oud is voorlichting over gezonde voeding van belang. Effectieve preventie én de integratie van preventie in de zorg levert gezondheidswinst en verhoging van kwaliteit van leven op individueel en populatie niveau. De Alliantie Voeding heeft hiertoe drie programma's opgesteld

At Your Request((R)) room service dining improves patient satisfaction, maintains nutritional status, and offers opportunities to improve intake

BACKGROUND: Malnutrition in hospitals may be combatted by improving the meal service. AIM: To evaluate whether At Your Request((R)), a meal service concept by Sodexo with a restaurant style menu card and room service, improved patient satisfaction, nutritional status, and food intake compared to the traditional 3-meals per day service. METHODS: We prospectively collected data in Hospital Gelderse Vallei (Ede, the Netherlands) before (2011/2012; n = 168, age 63 +/- 15 y) and after (2013/2014; n = 169, 66 +/- 15 y) implementing At Your Request((R)). RESULTS: Patient satisfaction increased after implementing At Your Request((R)) from 7.5 to 8.1 (scale 1-10) and from 124.5 to 132.9 points on a nutrition-related quality of life questionnaire (p /= 1; 47 vs 37). MUST scores improved in 18 patients in both periods. With At Your Request((R)) 0.92 g protein per kg (g/kg) bodyweight was ordered. Protein intake based on food records from patients on an energy and protein enriched diet was 0.84 g/kg during At Your Request((R)) (n = 38) versus 0.91 g/kg during the traditional meal service (n = 34). CONCLUSION: At Your Request((R)) is a highly rated hospital menu concept that helps patients to maintain nutritional status. The concept offers options for improving the intake of specific nutrients and foods, which should be evaluated in further studies

The sugar moiety is a major determinant of the absorption of dietary flavonoid glycosides in man

Flavonoids are antioxidants present in plant foods. They occur mainly as glycosides, i.e. linked with various sugars. It is uncertain to what extent dietary flavonoid glycosides are absorbed from the gut. We investigated how the nature of the sugar group affected absorption of one major flavonoid, quercetin. Quercetin linked with glucose, i.e. quercetin glucoside and quercetin linked with rutinose, i.e. quercetin rutinoside, both occur widely in foods. When we fed these compounds to nine volunteers, the peak concentration of quercetin (C(max)) in plasma was 20 times higher and was reached (T(max)) more than ten times faster after intake of the glucoside (C(max)=3.5±0.6 μM (mean±SE); T(max) < 0.5 h) than after the rutinoside (C(max) = 0.18 ± 0.04 μM; T(max) = 6.0 ± 1.2 h). The bioavailability of the rutinoside was only 20 f that of the glucoside. We suggest that quercetin glucoside is actively absorbed from the small intestine, whereas quercetin rutinoside is absorbed from the colon after deglycosylation. Absorption of other food components might also be enhanced by attachment of a glucose group

Meer patiënten eten bord leeg

Ziekenhuis Gelderse Vallei voerde in november 2012 het nieuwe maaltijd-serviceconcept At Your Request in. In april 2013 werd in een tussenmeting de hoeveelheid voedselverspilling gemeten. Eén van de uitkomsten is dat er veel minder voeding van patiënten terugkomt. Ook blijken zij daadwerkelijk meer te zijn gaan eten

Prevalence of Overweight in Dutch Children With Down Syndrome

Prevalence of overweight in children is increasing, causing various health problems. This study aims to establish growth references for weight and to assess the prevalence rates of overweight and obesity in a nationwide sample of Dutch children with Down syndrome (DS), taking into account the influence of comorbidity. METHODS: In 2009, longitudinal growth data from Dutch children with trisomy 21 who were born after 1982 were retrospectively collected from medical records of 25 Dutch regional specialized DS centers. “Healthy” was defined as not having concomitant disorders or having only a mild congenital heart defect. Weight and BMI references were calculated by using the LMS method, and prevalence rates of overweight and obesity by using cutoff values for BMI as defined by the International Obesity Task Force. Differences in prevalence rates were tested by multilevel logistic regression analyses to adjust for gender and age. RESULTS: Growth data of 1596 children with DS were analyzed. Compared with the general Dutch population, healthy children with DS were more often overweight (25.5% vs 13.3% in boys, and 32.0% vs 14.9% in girls) and obese (4.2% vs 1.8%, and 5.1% vs 2.2%, respectively). Prevalence rates of overweight between DS children with or without concomitant disorders did not vary significantly. CONCLUSIONS: Dutch children with DS have alarmingly high prevalence rates of overweight and obesity during childhood and adolescence. Health care professionals should be aware of the risk of overweight and obesity in children with DS to prevent complications