DIABETIC RETINOPATHY IMAGE CLASSIFICATION USING DEEP NEURAL NETWORK

Healthcare is an important field where image classification has an excellent value. An alarming healthcare problem recognized by the WHO that theworld suffers is diabetic retinopathy (DR). DR is a global epidemic which leads to the vision loss. Diagnosing the disease using fundus images is a timeconsuming task and needs experience clinicians to detect the small changes. Here, we are proposing an approach to diagnose the DR and its severity levels from fundus images using convolutional neural network algorithm (CNN). Using CNN, we are developing a training model which identifies the features through iterations. Later, this training model will classify the retina images of patients according to the severity levels. In healthcare field, efficiency and accuracy is important, so using deep learning algorithms for image classification can address these problems efficiently

Pathya Apathya of Visha w.s.r. to Prayoga Samucchaya

Agadatantra deals with the study of poison and its treatment and is given utmost importance among the branches of Ayurveda owing to its need for emergency management. Pathya Apathya is very important in the management of Visha Roga to keep the Dhatus in normal state and will not let them vitiated more by the action of Visha Gunas. People are exposed to different toxins, bites and stings and it’s the need of hour to understand properly about the Pathya Apathya to be followed in such conditions. This articles highlights the relevance of Pathya and Apathya in Visha Chikitsa from the malayalam text Prayoga Samucchaya

Microstrip antenna with DGS based on CSRR array for WiMAX applications

This paper reports a novel method for designing a miniaturized microstrip antenna with DGS based on CSRR array which operates in the frequency of 2.6GHz for low band WiMAX application. The proposed antenna is designed using ANSYS HFSS simulation software. The antenna with optimized parameters is fabricated using FR-4 substrate of thickness 1.6 mm. The simulated and measured performances of the antenna in terms of return loss, directivity and radiation patterns are presented in this work. When Complimentary Split Ring Resonators (CSRRs) array are placed on the ground plane, the resonant frequency is shifted  to a lower value and patch size is reduced .The measurements were taken and compared with the simulated results. The performance characteristics obtained from the measurements show that the proposed antenna is suited for WiMAX application at 2.6GHz

ROLE OF AGNI KARMA AND SNEHAPANA IN MANAGEMENT OF PAIN IN CERVICAL SPONDYLOSIS: A CASE STUDY

Introduction: Cervical spondylosis (Greevasthamba) is a degenerative condition with pain in cervical region as a major symptom. In modern science condition is usually treated with analgesic, corticosteroids, surgical decompression, traction etc. which not contribute much promising results. But in Ayurveda several methods like Snehana, Upanaha, Agnikarma, Raktamokshana and Panchakarma etc. are specified in management of pain. Case presentation: A male patient aged 42 years admitted CARIN-MSD, IPD with pain in the neck region since 2 months, which was also radiating to the right upper limb along with numbness up to the tip of fingers. Cervical active range of motions were painful during flexion, extension and lateral rotation. Spurling test and lhermittes sign were positive. Along with the support of X- ray and MRI investigations the patient was diagnosed with cervical spondylosis due to chronic postural strain. Management and Outcome:Patient was treated with Agnikarma and Snehapana, the pain score over visual analogue scale and NPQ percentage before treatment was Nine and 87.5 % respectively while after intervention it was reduced to Two and 33.33 % within seven days. Conclusion: In acute painful stage of cervical spondylosis Agnikarma and Snehapana can play a major role in management of pain

Treatment of wastewater from synthetic textile industry by electrocoagulation and electrooxidation

Treatment of wastewater from a textile industry that produces synthetic polyester cloths was studied employing electrochemical techniques. The sample was initially subjected to electrocoagulation to remove suspended solids. Mild steel and aluminum electrodes were tried as anodes; and aluminum was found to be effective for the removal of suspended solids. Using aluminum as anode, the chemical oxygen demand (COD) concentration of the effluent which was initially at the level of 1316 mg L−1 could be reduced to 429 mg L−1 by electrocoagulation. After electrocoagulation, the effluent was further subjected to electrooxidation using graphite and RuO2/IrO2/TaO2 coated titanium as anodes. During the electrooxidation tests, both COD and chloride ion were simultaneously estimated; and the effect of Cl− ion is discussed. The measurements have revealed the depletion of Cl− ion concentration implying the generation of free chlorine during electrooxidation. The depletion of Cl− ion concentration and the COD removal were observed to be comparatively high in the presence of graphite electrode. The effects of electrode materials and current density on COD removal are discussed. The instantaneous current efficiency (ICE), mass transfer coefficient and energy consumption were estimated

Contact Investigation of Bus Travelers Exposed to a Passenger with Contagious Tuberculosis

Multiple barriers exist to conducting contact investigations for tuberculosis after bus travel, and the degree of transmission risk to bus contacts is uncertain. We describe a patient with active infectious tuberculosis and the contact investigation that took place following her 5 hour bus trip across the United States-Canadian border

The platelet-surface thiol isomerase enzyme ERp57 modulates platelet function

Background: Thiol isomerases are a family of endoplasmic reticulum enzymes which orchestrate redox-based modifications of protein disulphide bonds. Previous studies have identified important roles for the thiol isomerases PDI and ERp5 in the regulation of normal platelet function. Objectives: Recently, we demonstrated the presence of a further five thiol isomerases at the platelet surface. In this report we aim to report the role of one of these enzymes - ERp57 in the regulation of platelet function. Methods/Results: Using enzyme activity function blocking antibodies, we demonstrate a role for ERp57 in platelet aggregation, dense granule secretion, fibrinogen binding, calcium mobilisation and thrombus formation under arterial conditions. In addition to the effects of ERp57 on isolated platelets, we observe the presence of ERp57 in the developing thrombus in vivo. Furthermore the inhibition of ERp57 function was found to reduce laser-injury induced arterial thrombus formation in a murine model of thrombosis. Conclusions: These data suggest that ERp57 is important for normal platelet function and opens up the possibility that the regulation of platelet function by a range of cell surface thiol isomerases may represent a broad paradigm for the regulation of haemostasis and thrombosis

PRESCRIPTION PATTERN OF ANTI-HYPERTENSIVE DRUGS IN A TERTIARY CARE HOSPITAL IN KERALA AND ADHERENCE TO JNC-8 GUIDELINES

Objective: Hypertension is a leading contributor to the global burden of cardiovascular morbidity and mortality. Worldwide prevalence is continuing to increase. Treatment for hypertension is constantly evolving and many new drugs are added at rapid pace. The objective of this study is to investigate utilization pattern of antihypertensive drugs in hypertensive patients in Azeezia institute of Medical Sciences and Research and to find its adherence to JNC-8 guidelines for management of hypertension. Methods: Descriptive drug utilization study was conducted on 266 hypertensive patients for period of 3 months. Data retrieved from patient's medical record. The study included all hypertensive patients with or without co-morbidities and above 18 yrs who attended out-patient department. Following classes of antihypertensive drugs were analyzed: Angiotensin Converting Enzyme Inhibitors (ACEI), Angiotensin Receptor blockers (ARB), beta blockers, calcium channel blockers, diuretics. ACEI/ARB was mostly prescribed which is in adherence to JNC-8 guidelines which recommends the use of ACEI/ARB as the first choice of drug. Results:  Hypertension is more prevalent in males than in females. ACEI/ARB are the most frequently prescribed classes of drugs alone or in combination, supporting the medication adherence to JNC-8 guidelines. Conclusion: The study concludes that the hypertension is more prevalent in males than in females, with its prevalence increasing with age. Peer Review History: Received 27 March 2018;   Revised 20 June; Accepted 8 July, Available online 15 July 2018 UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file:        Reviewer's Comments: Average Peer review marks at initial stage: 6/10 Average Peer review marks at publication stage: 8.5/10 Reviewer(s) detail: Dr. A.A. Mgbahurike, University of Port Harcourt, Nigeria, [email protected] Dr. Heba-Tallah Ahmed  Mohamed Moustafa, Heliopolis University Cairo, Egypt, [email protected] Similar Articles: CURRENT TREND OF RESISTANT FOR THE COMMONLY PRESCRIBED NEW FLUOROQUINOLONES AMONG HOSPITALISED PATIENTS IN SANA'A, YEME

Circularly Polarized Split Ring Resonator Loaded Slot Antenna

A compact circularly polarized printed slot antenna operating at 2.45 GHz is reported. The antenna consists of a pair of rotated square split ring resonators (SRR) inside a rectangular slot etched on the ground plane of an FR-4 dielectric substrate. A microstrip open-loop feed is etched on the backside of the dielectric substrate to feed the slot and the split ring resonators. The overall size of the antenna is 60x42x1.6 mm3. The measured -10dB impedance bandwidth is 10.48% (2.38-2.64 GHz) and the measured 3dB axial ratio (AR) bandwidth covers the entire impedance bandwidth

Environmental Fate of Zinc Oxide Nanoparticles: Risks and Benefits

Zinc oxide nanoparticles (ZnO-NPs) are among nanoscale materials displaying exponentially growing production due to their applications in the field of cosmetology, medicine, as antibacterial agent and catalyst. The ZnO nanomaterials release into the aquatic ecosystems through domestic and industrial wastewaters has the potential to induce pernicious effects on fish and other organisms. Increasing concerns on the environmental hazard to aquatic biota have been highlighted by the toxic potential of some metal-based nanomaterials. Several characteristics of ZnO-NPs (e.g. size, shape, surface charge and agglomeration state) play a central role in biological effects such as genotoxic, mutagenic or cytotoxic effects. Overall, Zn bioaccumulation, histopathological, and hematological changes with oxidative and cellular stress have been reported in ZnO-NPs exposed animals