Feynman-Jackson integrals

We introduce perturbative Feynman integrals in the context of q-calculus generalizing the Gaussian q-integrals introduced by Diaz and Teruel. We provide analytic as well as combinatorial interpretations for the Feynman-Jackson integrals.Comment: Final versio

Bispectrum signatures of a modified vacuum in single field inflation with a small speed of sound

Deviations from the Bunch-Davies vacuum during an inflationary period can leave a testable imprint on the higher-order correlations of the CMB and large scale structures in the Universe. The effect is particularly pronounced if the statistical non-Gaussianity is inherently large, such as in models of inflation with a small speed of sound, e.g. DBI. First reviewing the motivations for a modified vacuum, we calculate the non-Gaussianity for a general action with a small speed of sound. The shape of its bispectrum is found to most resemble the 'orthogonal' or 'local' templates depending on the phase of the Bogolyubov parameter. In particular, for DBI models of inflation the bispectrum can have a profound 'local' template feature, in contrast to previous results. Determining the projection into the observational templates allows us to derive constraints on the absolute value of the Bogolyubov parameter. In the small sound speed limit, the derived constraints are generally stronger than the existing constraint derived from the power spectrum. The bound on the absolute value of the Bogolyubov parameter ranges from the 10^-6 to the 10^-3 level for H/\Lambda_c = 10^-3, depending on the specific details of the model, the sound speed and the phase of the Bogolyubov parameter.Comment: 34 pages, 8 figures, 2 appendices. New in this version: added references, fixed typos, modified sentences. Version submitted to JCA

SAFT-γ force field for the simulation of molecular fluids: 8. hetero-group coarse-grained models of perfluoroalkylalkanes assessed with new vapour-liquid interfacial tension data

The air-liquid interfacial behaviour of linear perfluoroalkylalkanes (PFAAs) is reported through a combined experimental and computer simulation study. The surface tensions of seven liquid PFAAs (perfluorobutylethane, F4H2; perfluorobutylpentane, F4H5; perfluorobutylhexane, F4H6, perfluorobutyloctane, F4H8; perfluorohexylethane, F6H2; perfluorohexylhexane, F6H6; and perfluorohexyloctane, F6H8) are experimentally determined over a wide temperature range (276 to 350 K). The corresponding surface thermodynamic properties and the critical temperatures of the studied compounds are estimated from the temperature dependence of the surface tension. Experimental density and vapour pressure data are employed to parameterize a generic heteronuclear coarse-grained intermolecular potential of the SAFT- γ family for PFAAs. The resulting force field is used in direct molecular dynamics simulations to predict with quantitative agreement the experimental tensions and to explore the conformations of the molecules in the interfacial region revealing a preferential alignment of the PFAA molecules towards the interface and an enrichment of the perfluoro-groups at the outer interface region

Dosing strategies for switching from oral risperidone to paliperidone palmitate: Effects on clinical outcomes.

IntroductionThere are currently no guidelines for switching patients from oral risperidone to paliperidone palmitate (Invega Sustenna®). Furthermore, the paliperidone long-acting injectable (LAI) package insert does not recommend bridging with oral antipsychotics, which may result in inadequate serum concentrations in patients on ≥4 mg/d risperidone.MethodsThis study evaluated the effects of suboptimal dosing and bridging in patients switched from oral risperidone to paliperidone LAI on hospitalization days, emergency department (ED)/mental health urgent care visits, and no-shows/cancellations to mental health appointments. Patients were categorized into optimal or suboptimal dosing based on their loading and maintenance paliperidone doses. Patients on risperidone ≥4 mg/d were categorized as bridged if they received risperidone for ≥7 days after the first paliperidone injection.ResultsThere were no significant differences in outcomes between optimally and suboptimally dosed patients. There were statistically significant reductions in hospitalization days in patients who were bridged compared with patients who were not bridged. There were statistically significant reductions in hospitalization days and ED/mental health urgent care visits after switching to paliperidone LAI.DiscussionThe results of this study indicate that bridging patients who are on ≥4 mg/d risperidone, when converting to paliperidone LAI, is associated with reductions in hospitalization days. However, more research is required to determine the optimal dose and duration of the bridge. The results also indicate that switching patients from oral risperidone to paliperidone LAI, even if the dose is suboptimal, is associated with reductions in hospitalization days and ED/mental health urgent care visits

Imaging X-ray spectrometer

An X-ray spectrometer for providing imaging and energy resolution of an X-ray source is described. This spectrometer is comprised of a thick silicon wafer having an embedded matrix or grid of aluminum completely through the wafer fabricated, for example, by thermal migration. The aluminum matrix defines the walls of a rectangular array of silicon X-ray detector cells or pixels. A thermally diffused aluminum electrode is also formed centrally through each of the silicon cells with biasing means being connected to the aluminum cell walls and causes lateral charge carrier depletion between the cell walls so that incident X-ray energy causes a photoelectric reaction within the silicon producing collectible charge carriers in the form of electrons which are collected and used for imaging

Size-dependence of Strong-Coupling Between Nanomagnets and Photonic Cavities

The coherent dynamics of a coupled photonic cavity and a nanomagnet is explored as a function of nanomagnet size. For sufficiently strong coupling eigenstates involving highly entangled photon and spin states are found, which can be combined to create coherent states. As the size of the nanomagnet increases its coupling to the photonic mode also monotonically increases, as well as the number of photon and spin states involved in the system's eigenstates. For small nanomagnets the crystalline anisotropy of the magnet strongly localized the eigenstates in photon and spin number, quenching the potential for coherent states. For a sufficiently large nanomagnet the macrospin approximation breaks down and different domains of the nanomagnet may couple separately to the photonic mode. Thus the optimal nanomagnet size is just below the threshold for failure of the macrospin approximation.Comment: 10 pages, 7 figure

A PCA-based automated finder for galaxy-scale strong lenses

We present an algorithm using Principal Component Analysis (PCA) to subtract galaxies from imaging data, and also two algorithms to find strong, galaxy-scale gravitational lenses in the resulting residual image. The combined method is optimized to find full or partial Einstein rings. Starting from a pre-selection of potential massive galaxies, we first perform a PCA to build a set of basis vectors. The galaxy images are reconstructed using the PCA basis and subtracted from the data. We then filter the residual image with two different methods. The first uses a curvelet (curved wavelets) filter of the residual images to enhance any curved/ring feature. The resulting image is transformed in polar coordinates, centered on the lens galaxy center. In these coordinates, a ring is turned into a line, allowing us to detect very faint rings by taking advantage of the integrated signal-to-noise in the ring (a line in polar coordinates). The second way of analysing the PCA-subtracted images identifies structures in the residual images and assesses whether they are lensed images according to their orientation, multiplicity and elongation. We apply the two methods to a sample of simulated Einstein rings, as they would be observed with the ESA Euclid satellite in the VIS band. The polar coordinates transform allows us to reach a completeness of 90% and a purity of 86%, as soon as the signal-to-noise integrated in the ring is higher than 30, and almost independent of the size of the Einstein ring. Finally, we show with real data that our PCA-based galaxy subtraction scheme performs better than traditional subtraction based on model fitting to the data. Our algorithm can be developed and improved further using machine learning and dictionary learning methods, which would extend the capabilities of the method to more complex and diverse galaxy shapes

The (2√3×3)rect. phase of alkylthiolate self-assembled monolayers on Au(111): a symmetry-constrained structural solution

Low-energy electron-diffraction (LEED) patterns of the Au(111)(2√3×3)rect.-butylthiolate surface phase (a structure also seen in longer alkane chain thiolate self-assembled monolayers) show missing diffracted beams characteristic of glide symmetry, but do not show the larger set of missing beams found in surface x-ray diffraction (SXRD). The difference can be attributed to the greatly enhanced role of multiple scattering in LEED, but the combination of symmetry constraints placed on possible structural models by the observed SXRD and LEED beam extinctions greatly reduces the number of possible structural models. Only three such models are identified, one of which is clearly incompatible with other published experimental data. The relative merits of the remaining models, both involving Au adatom-thiolate moieties, are discussed in the light of the results of previous experimental studies