The non-linear evolution of bispectrum from the scale-free N-body simulation

We have accurately measured the bispectrum for four scale-free models of structure formation with the spectral index $n=1$, 0, -1, and -2. The measurement is based on a new method that can effectively eliminate the alias and numerical artifacts, and reliably extend the analysis into the strongly non-linear regime. The work makes use of a set of state-of-the art N-body simulations that have significantly increased the resolution range compared with the previous studies on the subject. With these measured results, we demonstrated that the measured bispectrum depends on the shape and size of $k$-triangle even in the strongly nonlinear regime. It increases with wavenumber and decreases with the spectral index. These results are in contrast with the hypothesis that the reduced bispectrum is a constant in the strongly non-linear regime. We also show that the fitting formula of Scoccimarro & Frieman (1999) does not describe our simulation results well (with a typical error about 40 percent). In the end, we present a new fitting formula for the reduced bispectrum that is valid for $-2 \leq n \leq 0$ with a typical error of 10 percent only.Comment: 33 pages, including 1 table, 14 figures, accepted by Ap

Accessing the Next Generation of Synthetic Mussel‐Glue Polymers via Mussel‐Inspired Polymerization

The formation of cysteinyldopa as biogenic connectivity in proteins is used to inspire a chemical pathway toward mussel-adhesive mimics. The mussel-inspired polymerization (MIPoly) exploits the chemically diverse family of bisphenol monomers that is oxidizable with 2-iodoxybenzoic acid to give bisquinones. Those react at room temperature with dithiols in Michael-type polyadditions, which leads to polymers with thiol–catechol connectivities (TCC). A set of TCC polymers proved adhesive behavior even on challenging poly(propylene) substrates, where they compete with commercial epoxy resins in dry adhesive strength. MIPoly promises facile scale up and exhibits high modularity to tailor adhesives, as proven on a small library where one candidate showed wet adhesion on aluminum substrates in both water and sea water models.Verband der Chemischen Industrie http://dx.doi.org/10.13039/100007215Deutsche Forschungsgemeinschaft http://dx.doi.org/10.13039/501100001659Peer Reviewe

Three-point correlation function of galaxy clusters in cosmological models: a strong dependence on triangle shape

In this paper, we use large \pppm N-body simulations to study the three-point correlation function \zeta of clusters in two theoretical models. The first model (LCDM) is a low-density flat model of \Omega_0=0.3, \Lambda_0=0.7 and h=0.75, and the second model (PIM) is an Einstein-de-Sitter model with its linear power spectrum obtained from observations. We found that the scaled function Q(r,u,v), which is defined as the ratio of \zeta (r, ru, ru+rv) to the hierarchical sum \xi (r)\xi (ru)+ \xi (ru) \xi (ru+rv) +\xi (ru+rv)\xi (r) (where \xi is the two-point correlation function of clusters), depends weakly on r and u, but very strongly on v. Q(r,u,v) is about 0.2 at v=0.1 and 1.8 at v=0.9. A model of Q(r,u,v)=\Theta 10^{1.3v^2} can fit the data of \zeta very nicely with \Theta\approx 0.14. This model is found to be universal for the LCDM clusters and for the PIM clusters. Furthermore, Q(r,u,v) is found to be insensitive to the cluster richness. We have compared our N-body results with simple analytical theories of cluster formation, like the peak theories or the local maxima theories. We found that these theories do not provide an adequate description for the three-point function of clusters. We have also examined the observational data of \zeta presently available, and have not found any contradiction between the observations and our model predictions. The v-dependence of q in a projected catalogue of clusters is shown to be much weaker than the v-dependence of Q found in the three-dimensional case. It would be important to search for the v-dependence of Q in redshift samples of rich clusters

Peptide-Assisted Design of Precision Polymer Sequences

Functional sequences of monodisperse, sequence‐defined oligo(amide‐urethane)s are designed based on a peptide sequence as blueprint. The translation of a discrete side‐chain functionality sequence from a known peptide‐based solubilizer of the photosensitizer meta‐tetra(hydroxyphenyl)‐chlorin, into a non‐peptidic precision polymer backbone is demonstrated. The resulting peptidomimetic precision polymers retain the functions of the parent peptide sequence, showing analogues sensitivity toward single monomer mutations/exchanges and even exceeding the parent peptide equivalent by reaching up to 69% higher payload capacities and more favored release kinetics.Peer Reviewe

Function of a Novel Checkpoint Protein in the Germ Line

Successful reproduction of Saccharomyces cerevisiae relies on the organism’s ability to complete the meiotic cell cycle and produce viable gametes. Zip1 is a protein that constitutes the central component of a protein structure that connects homologous chromosomes known as the synaptonemal complex. Zip1 is important for progression through the meiotic cell cycle. The C terminus of the coiled-coil Zip 1 protein is responsible for localization to the axes of the chromosomes. An internal deletion near the C terminus of Zip1, called zip1-c1, yields a stronger meiotic arrest than a mutation where Zip1 is completely deleted. The more efficient meiotic progression in a Zip1 deletion mutation versus the zip1-c1 mutant suggests that zip1-c1 prevents an alternative pathway of meiotic progression. A genomic screen of the Nasmyth genomic library revealed candidate plasmids N5 and N89 containing yeast genes which, when overexpressed, increase spore viability and bypass meiotic arrest in the zip1-c1 mutant. This has implications that the genes on the overexpression plasmids serve some function in correcting mistakes in meiosis when Zip1 is mutated.https://engagedscholarship.csuohio.edu/u_poster_2013/1014/thumbnail.jp

A cosmological model in Weyl-Cartan spacetime

We present a cosmological model for early stages of the universe on the basis of a Weyl-Cartan spacetime. In this model, torsion $T^{\alpha}$ and nonmetricity $Q_{\alpha \beta}$ are proportional to the vacuum polarization. Extending earlier work of one of us (RT), we discuss the behavior of the cosmic scale factor and the Weyl 1-form in detail. We show how our model fits into the more general framework of metric-affine gravity (MAG).Comment: 19 pages, 5 figures, typos corrected, uses IOP style fil

Complex Systems Science: Dreams of Universality, Reality of Interdisciplinarity

Using a large database (~ 215 000 records) of relevant articles, we empirically study the "complex systems" field and its claims to find universal principles applying to systems in general. The study of references shared by the papers allows us to obtain a global point of view on the structure of this highly interdisciplinary field. We show that its overall coherence does not arise from a universal theory but instead from computational techniques and fruitful adaptations of the idea of self-organization to specific systems. We also find that communication between different disciplines goes through specific "trading zones", ie sub-communities that create an interface around specific tools (a DNA microchip) or concepts (a network).Comment: Journal of the American Society for Information Science and Technology (2012) 10.1002/asi.2264

Ligating Catalytically Active Peptides onto Microporous Polymers: A General Route Toward Specifically-Functional High Surface Area Platforms

A versatile post-synthetic modification strategy to functionalize a high surface area microporous network (MPN-OH) by bio-orthogonal inverse electron-demand Diels-Alder (IEDDA) ligation is presented. While the polymer matrix is modified with a readily accessible norbornene isocyanate (Nor-NCO), a series of functional units presenting the robust asymmetric 1,2,4,5-tetrazine (Tz) allows easy functionalization of the MPN by chemoselective Nor/Tz ligation. A generic route is demonstrated, modulating the internal interfaces by introducing carboxylates, amides or amino acids as well as an oligopeptide d-Pro-Pro-Glu organocatalyst. The MPN-Pz-Peptide construct largely retains the catalytic activity and selectivity in an enantioselective enamine catalysis, demonstrates remarkable availability in different solvents, offers heterogeneous organocatalysis in bulk and shows stability in recycling settings.Peer Reviewe