897 research outputs found

    A new accurate approximation of the Gaussian Q-function with relative error less than 1 thousandth in a significant domain

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    The approximations of the Gaussian Q-function found in the literature have been often developed with the goal of obtaining high estimation accuracies in deriving the error probability for digital modulation schemes. Unfortunately, the obtained mathematical expressions are often too complex, even difficultly tractable. A new approximation for the Gaussian Q-function is presented in the form of the standard normal density multiplied by a rational function. The rational function is simply a linear combination of the first 5 integer negative powers of the same term, linear in x, using only 4 decimal constants. In this paper we make some considerations about the significant interval where to consider the Q-function in telecommunication theory. The relative error in absolute value of the given approximation is less than 0.06% in the considered significant interval

    Performance Study of a Class of Irregular Near Capacity Achieving LDPC Codes

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    This paper investigates the performance of a class of irregular low-density parity-check (LDPC) codes through a recently published low complexity upper bound on their beliefpropagation decoding thresholds. Moreover, their performance analysis is carried out through a recently published algorithmic method, presented in Babich et al. 2017 paper. In particular, the class considered is characterized by variable node degree distributions λ(x) of minimum degree i1 > 2: being, in this case, λ0(0) = λ2 = 0, this is useful to design LDPC codes presenting a linear minimum distance growth with the block length with probability 1, as shown in Di et al.'s 2006 paper. These codes unfortunately cannot reach capacity under iterative decoding, since the achievement of capacity requires λ2 ≠ 0. However, in this latter case, the block error probability might converge to a constant, as shown in the aforementioned paper

    Understanding the evolution of native pinewoods in Scotland will benefit their future management and conservation

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    Scots pine (Pinus sylvestris L.) is a foundation species in Scottish highland forests and a national icon. Due to heavy exploitation, the current native pinewood coverage represents a small fraction of the postglacial maximum. To reverse this decline, various schemes have been initiated to promote planting of new and expansion of old pinewoods. This includes the designation of seed zones for control of the remaining genetic resources. The zoning was based mainly on biochemical similarity among pinewoods but, by definition, neutral molecular markers do not reflect local phenotypic adaptation. Environmental variation within Scotland is substantial and it is not yet clear to what extent this has shaped patterns of adaptive differentiation among Scottish populations. Systematic, rangewide common-environment trials can provide insights into the evolution of the native pinewoods, indicating how environment has influenced phenotypic variation and how variation is maintained. Careful design of such experiments can also provide data on the history and connectivity among populations, by molecular marker analysis. Together, phenotypic and molecular datasets from such trials can provide a robust basis for refining seed transfer guidelines for Scots pine in Scotland and should form the scientific basis for conservation action on this nationally important habitat

    The critical dimension for a 4th order problem with singular nonlinearity

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    We study the regularity of the extremal solution of the semilinear biharmonic equation \bi u=\f{\lambda}{(1-u)^2}, which models a simple Micro-Electromechanical System (MEMS) device on a ball B\subset\IR^N, under Dirichlet boundary conditions u=νu=0u=\partial_\nu u=0 on B\partial B. We complete here the results of F.H. Lin and Y.S. Yang \cite{LY} regarding the identification of a "pull-in voltage" \la^*>0 such that a stable classical solution u_\la with 0 exists for \la\in (0,\la^*), while there is none of any kind when \la>\la^*. Our main result asserts that the extremal solution uλu_{\lambda^*} is regular (supBuλ<1)(\sup_B u_{\lambda^*} <1) provided N8 N \le 8 while uλu_{\lambda^*} is singular (supBuλ=1\sup_B u_{\lambda^*} =1) for N9N \ge 9, in which case 1C0x4/3uλ(x)1x4/31-C_0|x|^{4/3}\leq u_{\lambda^*} (x) \leq 1-|x|^{4/3} on the unit ball, where C0:=(λλ)1/3 C_0:= (\frac{\lambda^*}{\overline{\lambda}})^{1/3} and λˉ:=8/9(N2/3)(N8/3) \bar{\lambda}:= {8/9} (N-{2/3}) (N- {8/3}).Comment: 19 pages. This paper completes and replaces a paper (with a similar title) which appeared in arXiv:0810.5380. Updated versions --if any-- of this author's papers can be downloaded at this http://www.birs.ca/~nassif

    MLP: a MATLAB toolbox for rapid and reliable auditory threshold estimation

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    In this paper, we present MLP, a MATLAB toolbox enabling auditory thresholds estimation via the adaptive Maximum Likelihood procedure proposed by David Green (1990, 1993). This adaptive procedure is particularly appealing for those psychologists that need to estimate thresholds with a good degree of accuracy and in a short time. Together with a description of the toolbox, the current text provides an introduction to the threshold estimation theory and a theoretical explanation of the maximum likelihood adaptive procedure. MLP comes with a graphical interface and it is provided with several built-in, classic psychoacoustics experiments ready to use at a mouse click

    Results of the IGEC-2 search for gravitational wave bursts during 2005

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    The network of resonant bar detectors of gravitational waves resumed coordinated observations within the International Gravitational Event Collaboration (IGEC-2). Four detectors are taking part in this collaboration: ALLEGRO, AURIGA, EXPLORER and NAUTILUS. We present here the results of the search for gravitational wave bursts over 6 months during 2005, when IGEC-2 was the only gravitational wave observatory in operation. The network data analysis implemented is based on a time coincidence search among AURIGA, EXPLORER and NAUTILUS, keeping the data from ALLEGRO for follow-up studies. With respect to the previous IGEC 1997-2000 observations, the amplitude sensitivity of the detectors to bursts improved by a factor about 3 and the sensitivity bandwidths are wider, so that the data analysis was tuned considering a larger class of detectable waveforms. Thanks to the higher duty cycles of the single detectors, we decided to focus the analysis on three-fold observation, so to ensure the identification of any single candidate of gravitational waves (gw) with high statistical confidence. The achieved false detection rate is as low as 1 per century. No candidates were found.Comment: 10 pages, to be submitted to Phys. Rev.

    Genetic Determinants of Variability in Glycated Hemoglobin (HbA1c) in Humans: Review of Recent Progress and Prospects for Use in Diabetes Care

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    Glycated hemoglobin A1c (HbA1c) indicates the percentage of total hemoglobin that is bound by glucose, produced from the nonenzymatic chemical modification by glucose of hemoglobin molecules carried in erythrocytes. HbA1c represents a surrogate marker of average blood glucose concentration over the previous 8 to 12 weeks, or the average lifespan of the erythrocyte, and thus represents a more stable indicator of glycemic status compared with fasting glucose. HbA1c levels are genetically determined, with heritability of 47% to 59%. Over the past few years, inroads into understanding genetic predisposition by glycemic and nonglycemic factors have been achieved through genome-wide analyses. Here I review current research aimed at discovering genetic determinants of HbA1c levels, discussing insights into biologic factors influencing variability in the general and diabetic population, and across different ethnicities. Furthermore, I discuss briefly the relevance of findings for diabetes monitoring and diagnosis

    Global gene expression analysis of human erythroid progenitors

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    This article is available open access through the publisher’s website. Copyright @ 2011 American Society of Hematology. This article has an erratum: http://bloodjournal.hematologylibrary.org/content/118/26/6993.3.Understanding the pattern of gene expression during erythropoiesis is crucial for a synthesis of erythroid developmental biology. Here, we isolated 4 distinct populations at successive erythropoietin-dependent stages of erythropoiesis, including the terminal, pyknotic stage. The transcriptome was determined using Affymetrix arrays. First, we demonstrated the importance of using defined cell populations to identify lineage and temporally specific patterns of gene expression. Cells sorted by surface expression profile not only express significantly fewer genes than unsorted cells but also demonstrate significantly greater differences in the expression levels of particular genes between stages than unsorted cells. Second, using standard software, we identified more than 1000 transcripts not previously observed to be differentially expressed during erythroid maturation, 13 of which are highly significantly terminally regulated, including RFXAP and SMARCA4. Third, using matched filtering, we identified 12 transcripts not previously reported to be continuously up-regulated in maturing human primary erythroblasts. Finally, using transcription factor binding site analysis, we identified potential transcription factors that may regulate gene expression during terminal erythropoiesis. Our stringent lists of differentially regulated and continuously expressed transcripts containing many genes with undiscovered functions in erythroblasts are a resource for future functional studies of erythropoiesis. Our Human Erythroid Maturation database is available at https://cellline.molbiol.ox.ac.uk/eryth/index.html.National Health Service Blood and Transplant, National Institute for Health Research Biomedical Research Center Program, and National Institute for Health Research
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