87 research outputs found
Ultrastrong coupling between electron tunneling and mechanical motion
The ultrastrong coupling of single-electron tunneling and nanomechanical
motion opens exciting opportunities to explore fundamental questions and
develop new platforms for quantum technologies. We have measured and modelled
this electromechanical coupling in a fully-suspended carbon nanotube device and
report a ratio of , where ~MHz is the
coupling strength and ~MHz is the mechanical resonance
frequency. This is well within the ultrastrong coupling regime and the highest
among current electromechanical platforms. Even higher ratios could be achieved
with improvement on device design
Stability of long-sustained oscillations induced by electron tunneling
Self-oscillations are the result of an efficient mechanism generating
periodic motion from a constant power source. In quantum devices, these
oscillations may arise due to the interaction between single electron dynamics
and mechanical motion. Due to the complexity of this mechanism, these
self-oscillations may irrupt, vanish, or exhibit a bistable behavior causing
hysteresis cycles. We observe these hysteresis cycles and characterize the
stability of different regimes in single and double quantum dot configurations.
In particular cases, we find these oscillations stable for over 20 seconds,
many orders of magnitude above electronic and mechanical characteristic
timescales, revealing the robustness of the mechanism at play. The experimental
results are reproduced by our theoretical model that provides a complete
understanding of bistability in nanoelectromechanical devices.Comment: 11 pages, 10 figures, includes the complete paper and the
Supplemental Materia
Intraperitoneal adoptive transfer of mesenchymal stem cells enhances recovery from acid aspiration acute lung injury in mice
e-Pilly TROP Maladies infectieuses tropicales
L’e-Pilly TROP est un ouvrage d’infectiologie tropicale destiné aux médecins et aux étudiants en médecine des pays francophones du Sud. La prise en compte des différents niveaux de la pyramide sanitaire dans ces pays le rend aussi accessible aux infirmiers des centres de santé communautaires urbains et des structures de santé intermédiaires des zones rurales. Par définition, les Pays En Développement accroissant progressivement leurs capacités de diagnostic biologique et de traitement, les outils de prise en charge correspondent aux moyens des niveaux périphériques comme à ceux des niveaux hospitaliers de référence
Future Perspectives of Bone Tissue Engineering with Special Emphasis on Extracellular Vesicles
Peer reviewe
Constitutive activation of the ERK pathway in melanoma and skin melanocytes in Grey horses
Neutrophil expression of glucocorticoid-induced leucine zipper (GILZ) anti-inflammatory protein is associated with acute respiratory distress syndrome severity
Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome associated with COVID-19: An Emulated Target Trial Analysis.
RATIONALE: Whether COVID patients may benefit from extracorporeal membrane oxygenation (ECMO) compared with conventional invasive mechanical ventilation (IMV) remains unknown. OBJECTIVES: To estimate the effect of ECMO on 90-Day mortality vs IMV only Methods: Among 4,244 critically ill adult patients with COVID-19 included in a multicenter cohort study, we emulated a target trial comparing the treatment strategies of initiating ECMO vs. no ECMO within 7 days of IMV in patients with severe acute respiratory distress syndrome (PaO2/FiO2 <80 or PaCO2 ≥60 mmHg). We controlled for confounding using a multivariable Cox model based on predefined variables. MAIN RESULTS: 1,235 patients met the full eligibility criteria for the emulated trial, among whom 164 patients initiated ECMO. The ECMO strategy had a higher survival probability at Day-7 from the onset of eligibility criteria (87% vs 83%, risk difference: 4%, 95% CI 0;9%) which decreased during follow-up (survival at Day-90: 63% vs 65%, risk difference: -2%, 95% CI -10;5%). However, ECMO was associated with higher survival when performed in high-volume ECMO centers or in regions where a specific ECMO network organization was set up to handle high demand, and when initiated within the first 4 days of MV and in profoundly hypoxemic patients. CONCLUSIONS: In an emulated trial based on a nationwide COVID-19 cohort, we found differential survival over time of an ECMO compared with a no-ECMO strategy. However, ECMO was consistently associated with better outcomes when performed in high-volume centers and in regions with ECMO capacities specifically organized to handle high demand. This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives License 4.0 (http://creativecommons.org/licenses/by-nc-nd/4.0/)
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