Invitro Antibacterial Screening of Extracts from Selected Ethiopian Medicinal Plants

Indigenous knowledge, literature reports and ethnobotanical records suggest that plants are the basis for medicines. They constitute natural source of antimicrobial drugs that will provide novel or lead compounds for the fight against disease. In this study, the antimicrobial activity of three selected Ethiopian medicinal plants was studied with the objective of  screening their antibacterial activity. The fruits of Measalanceolata, aerial part of Cissus quadrangularis and leaf of Dodonae angustifolia were collected, air dried under shed, powdered and soaked in 80% methanol and extracted. In vitro antibacterial activity of the extracts was tested at different concentrations by using agar disc diffusion method and  measuring the zone of inhibition. The plant extracts showed broad  spectrum activity against gram positive (S. aureus) as well as gram  negative (E. coli) bacteria, except Cissus quadrangularis which did not show any activity against E. coli. Furthermore, the plant extracts had also  concentration dependant zone of inhibition against the tested bacteria. In fact, the highest activity was obtained for Dodonae angustifolia at  1000mg/ml against S. aureus. The activities are attributed to the presence of some secondary metabolites present in the tested plants which have been associated with antibacterial activities. This finding suggests that these medicinal plants can be potential source to isolate antibacterial drugs.Keywords: Antibacterial activity, Disc diffusion, E. coli, Plant extract and S. aureus

Hydrological Foundation as a Basis for a Holistic Environmental Flow Assessment of Tropical Highland Rivers in Ethiopia

The sustainable development of water resources includes retaining some amount of the natural flow regime in water bodies to protect and maintain aquatic ecosystem health and the human livelihoods and wellbeing dependent upon them. Although assessment of environmental flows is now occurring globally, limited studies have been carried out in the Ethiopian highlands, especially studies to understand flow-ecological response relationships. This paper establishes a hydrological foundation of Gumara River from an ecological perspective. The data analysis followed three steps: first, determination of the current flow regime flow indices and ecologically relevant flow regime; second, naturalization of the current flow regime looking at how flow regime is changing; and, finally, an initial exploration of flow linkages with ecological processes. Flow data of Gumara River from 1973 to 2018 are used for the analysis. Monthly low flow occurred from December to June; the lowest being in March, with a median flow of 4.0 m(3) s(-1). Monthly high flow occurred from July to November; the highest being in August, with a median flow of 236 m(3) s(-1). 1-Day low flows decreased from 1.55 m(3) s(-1) in 1973 to 0.16 m(3) s(-1) in 2018, and 90-Day (seasonal) low flow decreased from 4.9 m(3) s(-1) in 1973 to 2.04 m(3) s(-1) in 2018. The Mann-Kendall trend test indicated that the decrease in low flow was significant for both durations at alpha = 0.05. A similar trend is indicated for both durations of high flow. The decrease in both low flows and high flows is attributed to the expansion of pump irrigation by 29 km(2) and expansion of plantations, which resulted in an increase of NDVI from 0.25 in 2000 to 0.29 in 2019. In addition, an analysis of environmental flow components revealed that only four "large floods" appeared in the last 46 years; no "large flood" occurred after 1988. Lacking "large floods" which inundate floodplain wetlands has resulted in early disconnection of floodplain wetlands from the river and the lake; which has impacts on breeding and nursery habitat shrinkage for migratory fish species in Lake Tana. On the other hand, the extreme decrease in "low flow" components has impacts on pin smaller pools. These results serve as the hydrological foundation for continued studies in the Gumara catchment, with the eventual goal of quantifying environmental flow requirements.redators, reducing their mobility and ability to access prey concentrate

Brief communication: Low prevalence of HIV infection, and knowledge, attitude and practice on HIV/AIDS among high school students in Gondar, Northwest Ethiopia

HIV/AIDS is a major public health problem in Ethiopia. Therefore, a school based cross-sectional study was conducted in Gondar; Northwest Ethiopia to determine the seroprevalence of HIV infection and to assess Knowledge, attitude and practice related to HIV/AIDS. A total of 565 students were included in the study. The seroprevalence of HIV infection was 1.1%. Sexual contact with commercial sex worker or non-regular partner was reported by 16.7% of the students. Only 58.5% of those who practice sex used condoms. History of sexually transmitted diseases was reported by 10.7% of the sexually active students. The majority (96.6%) reported unprotected sex, unsafe blood transfusion, contaminated needles and mother to child transmissions as common ways of HIV transmission. Abstinence, faithfulness to one\'s partner and use of condom as means to prevent transmission of HIV was responded by 84.1%, 60.4% and 41.8% of the students, respectively. Over 82% demanded screening for HIV as a precondition for marriage and 97.2% agreed to have a VCT service. The findings of the study indicate that the prevalence of HIV infection is low among high school students in Gondar. The students had adequate knowledge about HIV/AIDS and VCT despite the risky practices. Continued health education is needed to bring behavioral changes.The Ethiopian Journal of Health Development Vol. 21 (2) 2007: pp. 179-18

Multiregional Satellite Precipitation Products Evaluation over Complex Terrain

An extensive evaluation of nine global-scale high-resolution satellite-based rainfall (SBR) products is performed using a minimum of 6 years (within the period of 2000-13) of reference rainfall data derived from rain gauge networks in nine mountainous regions across the globe. The SBR products are compared to a recently released global reanalysis dataset from the European Centre for Medium-Range Weather Forecasts (ECMWF). The study areas include the eastern Italian Alps, the Swiss Alps, the western Black Sea of Turkey, the French Cévennes, the Peruvian Andes, the Colombian Andes, the Himalayas over Nepal, the Blue Nile in East Africa, Taiwan, and the U.S. Rocky Mountains. Evaluation is performed at annual, monthly, and daily time scales and 0.25° spatial resolution. The SBR datasets are based on the following retrieval algorithms: Tropical Rainfall Measuring Mission Multisatellite Precipitation Analysis (TMPA), the NOAA/Climate Prediction Center morphing technique (CMORPH), Precipitation Estimation from Remotely Sensed Information Using Artificial Neural Networks (PERSIANN), and Global Satellite Mapping of Precipitation (GSMaP). SBR products are categorized into those that include gauge adjustment versus unadjusted. Results show that performance of SBR is highly dependent on the rainfall variability. Many SBR products usually underestimate wet season and overestimate dry season precipitation. The performance of gauge adjustment to the SBR products varies by region and depends greatly on the representativeness of the rain gauge network

Potential of Water Hyacinth Infestation on Lake Tana, Ethiopia: A Prediction Using a GIS-Based Multi-Criteria Technique

Water hyacinth is a well-known invasive weed in lakes across the world and harms the aquatic environment. Since 2011, the weed has invaded Lake Tana substantially posing a challenge to the ecosystem services of the lake. The major factors which affect the growth of the weed are phosphorus, nitrogen, temperature, pH, salinity, and lake depth. Understanding and investigating the hotspot areas is vital to predict the areas for proper planning of interventions. The main objective of this study is therefore to predict the hotspot areas of the water hyacinth over the surface of the lake using the geographical information system (GIS)-based multi-criteria evaluation (MCE) technique. The main parameters used in the multi-criteria analysis were total phosphorus (\u3e0.08 mg L−1), total nitrogen (\u3e1.1 mg L−1), temperature (\u3c26.2 °C), pH (\u3c8.6), salinity (\u3c0.011%), and depth (\u3c6 m). These parameters were collected from 143 sampling sites on the lake in August, December (2016), and March (2017). Fuzzy overlay spatial analysis was used to overlay the different parameters to obtain the final prediction map of water hyacinth infestation areas. The results indicated that 24,969 ha (8.1%), 21,568.7 ha (7.1%), and 24,036 ha (7.9%) of the lake are susceptible to invasion by the water hyacinth in August, December, and March, respectively. At the maximum historical lake level, 30,728.4 ha will be the potential susceptible area for water hyacinth growth and expansion at the end of the rainy season in August. According to the result of this study, the north and northeastern parts of the lake are highly susceptible for invasion. Hence, water hyacinth management and control plans shall mainly focus on the north and northeastern part of Lake Tana and upstream contributing watersheds

Undernutrition among Ethiopian adults living with HIV: a meta-analysis.

BackgroundMalnutrition and human immunodeficiency virus (HIV) are interlaced in a vicious cycle and worsened in low and middle-income countries. In Ethiopia, even though individuals are dually affected by both malnutrition and HIV, there is no a nationwide study showing the proportion of malnutrition among HIV-positive adults. Consequently, this review addressed the pooled burden of undernutrition among HIV-positive adults in Ethiopia.MethodsWe searched for potentially relevant studies through manual and electronic searches. An electronic search was carried out using the database of PubMed, Google Scholar, and Google for gray literature and reference lists of previous studies. A standardized data extraction checklist was used to extract the data from each original study. STATA Version 13 statistical software was used for our analysis. Descriptive summaries were presented in tables, and the quantitative result was presented in a forest plot. Heterogeneity within the included studies was examined using the Cochrane Q test statistics and I 2 test. Finally, a random-effects meta-analysis model was computed to estimate the pooled proportion of undernutrition among HIV-positive adults.ResultsAfter reviewing 418 studies, 15 studies met the inclusion criteria and were included in the meta-analysis. Findings from 15 studies revealed that the pooled percentage of undernutrition among HIV-positive adults in Ethiopia was 26% (95% CI: 22, 30%). The highest percentage of undernutrition (46.8%) was reported from Jimma University specialized hospital, whereas the lowest proportion of undernutrition (12.3%) was reported from Dilla Hospital. The subgroup analyses of this study also indicated that the percentage of undernourishment among HIV-positive adults is slightly higher in the Northern and Central parts of Ethiopia (27.5%) as compared to the Southern parts of Ethiopia (25%).ConclusionThis study noted that undernutrition among HIV-positive adults in Ethiopia was quite common. This study also revealed that undernutrition is more common among HIV-positive adults with advanced disease stage, anemia, diarrhea, CD4 count less than 200 cells/mm3, and living in rural areas. Based on our findings, we suggested that all HIV-positive adults should be assessed for nutritional status at the time of ART commencement

Forest and landscape restoration opportunities in the western catchment of Lake Ziway, Central Rift Valley, Ethiopia: technical report

Forest and landscape restoration measures could address landscape degradation, increase ecosystem services, and improve livelihoods. However, mapping potential areas for forest and landscape restoration measures and identifying enabling and constraining factors is crucial for effective implementation. This study was conducted in the western catchment of Lake Ziway, Central Rift Valley, Ethiopia, to identify potential forest and landscape restoration options, map potential areas, assess the benefits and cost of options, and investigate success and failure factors for implementing interventions. The study adopted the Restoration Opportunities Assessment Methodology (ROAM), which enables selecting and mapping forest and landscape restoration options. Data were collected using field surveys, key informant interviews, focus group discussion and literature reviews. We also employed GIS and remote sensing methods to characterize the long-term land use and land-cover dynamics and changes in the status of land degradation. Cost–benefit analysis was conducted to assess the economic viability of identified restoration options. The results suggested that over the last 20 years (2002 to 2022), the western catchment of Lake Ziway experienced severe forest and landscape degradation due to anthropogenic and climatic factors, resulting in multiple environmental and socioeconomic consequences. This study identified seven context-specific forest and landscape restoration measures to address the problem. They vary in cost, trajectory and specific economic and social outcomes. Most options were economically viable with additional environmental and social benefits. For example, the benefit of carbon sequestration for home garden agroforestry was estimated at USD 27,032.5 ha-1 over 20 years. It was also found that a considerable portion of the catchment area was potentially suitable for agroforestry practices (40%), particularly for scattered trees on farmlands. However, the potential areas suitable for full afforestation or reforestation and tree buffers are smaller (6%). Integrating multiple forest and landscape restoration measures in the catchment could maximize the environmental and socioeconomic outcomes. Opportunities to effectively implement and scale up the identified forest and landscape restoration options include the availability of adequate active labor, the diverse benefits of measures, and the existence of supporting policies and strategies, multiple potential financing mechanisms and active development of governmental and non-governmental organizations. However, the absence of guidelines for implementing legal issues, weak coordination among responsible institutions, and inadequate finance and incentives have been identified as major constraints to scale up forest and landscape restoration measures. The findings of this study may serve as a guide for the planning, design and implementation of restoration measures in the study catchment and similar future projects in other catchments

Using qualitative methods to explore lay explanatory models, health-seeking behaviours and self-care practices of podoconiosis patients in north-west Ethiopia

Background: Podoconiosis (endemic non-filarial elephantiasis) is a chronic, non-infectious disease resulting from exposure of bare feet to red-clay soil in tropical highlands. This study examined lay beliefs about three under-researched aspects of podoconiosis patients’ care: explanatory models, health-seeking behaviours and self-care. Methods: In-depth interviews and focus group discussions were undertaken with 34 participants (19 male, 15 female) between April-May 2015 at podoconiosis treatment centres across East and West Gojjam regions in north-west Ethiopia. Results: Explanatory models for podoconiosis included contamination from blood, magic, soil or affected individuals. Belief in heredity or divine punishment often delayed clinic attendance. All participants had tried holy water treatment and some, holy soil. Herbal treatments were considered ineffectual, costly and appeared to promote fluid escape. Motivators for clinic attendance were failure of traditional treatments and severe or disabling symptoms. Patients did not report self-treatment with antibiotics. Self-care was hindered by water being unavailable or expensive and patient fatigue. Conclusion: A pluralistic approach to podoconiosis self-treatment was discovered. Holy water is widely valued, though some patients prefer holy soil. Priests and traditional healers could help promote self-care and “signpost” patients to clinics. Change in behaviour and improving water access is key to self-care

Exploring temporality in socio-ecological resilience through experiences of the 2015–16 El Niño across the Tropics

In a context of both long-term climatic changes and short-term climatic shocks, temporal dynamics profoundly influence ecosystems and societies. In low income contexts in the Tropics, where both exposure and vulnerability to climatic fluctuations is high, the frequency, duration, and trends in these fluctuations are important determinants of socio-ecological resilience. In this paper, the dynamics of six diverse socio-ecological systems (SES) across the Tropics – ranging from agricultural and horticultural systems in Africa and Oceania to managed forests in South East Asia and coastal systems in South America – are examined in relation to the 2015–16 El Niño, and the longer context of climatic variability in which this short-term ‘event’ occurred. In each case, details of the socio-ecological characteristics of the systems and the climate phenomena experienced during the El Niño event are described and reflections on the observed impacts of, and responses to it are presented. Drawing on these cases, we argue that SES resilience (or lack of) is, in part, a product of both long-term historical trends, as well as short-term shocks within this history. Political and economic lock-ins and dependencies, and the memory and social learning that originates from past experience, all contribute to contemporary system resilience. We propose that the experiences of climate shocks can provide a window of insight into future ecosystem responses and, when combined with historical perspectives and learning from multiple contexts and cases, can be an important foundation for efforts to build appropriate long-term resilience strategies to mediate impacts of changing and uncertain climates