522 research outputs found
Coherent Time Evolution and Boundary Conditions of Two-Photon Quantum Walks
Multi-photon quantum walks in integrated optics are an attractive controlled
quantum system, that can mimic less readily accessible quantum systems and
exhibit behavior that cannot in general be accurately replicated by classical
light without an exponential overhead in resources. The ability to observe time
evolution of such systems is important for characterising multi-particle
quantum dynamics---notably this includes the effects of boundary conditions for
walks in spaces of finite size. Here we demonstrate the coherent evolution of
quantum walks of two indistinguishable photons using planar arrays of 21
evanescently coupled waveguides fabricated in silicon oxynitride technology. We
compare three time evolutions, that follow closely a model assuming unitary
evolution, corresponding to three different lengths of the array---in each case
we observe quantum interference features that violate classical predictions.
The longest array includes reflecting boundary conditions.Comment: 7 pages,7 figure
Cellular Internalization of Human Calcitonin Derived Peptides in MDCK Monolayers: A Comparative Study with Tat(47-57) and Penetratin(43-58)
ISSN:0724-8741ISSN:1573-904
The nonrelativistic limit of the Majorana equation and its simulation in trapped ions
We analyze the Majorana equation in the limit where the particle is at rest.
We show that several counterintuitive features, absent in the rest limit of the
Dirac equation, do appear. Among them, Dirac-like positive energy solutions
that turn into negative energy ones by free evolution, or nonstandard
oscillations and interference between real and imaginary spinor components for
complex solutions. We also study the ultrarelativistic limit, showing that the
Majorana and Dirac equations mutually converge. Furthermore, we propose a
physical implementation in trapped ions.Comment: 7 pages, 1 figure. Proceedings of 18th Central European Workshop on
Quantum Optics (CEWQO 2011), Madrid, Spai
On the experimental verification of quantum complexity in linear optics
The first quantum technologies to solve computational problems that are
beyond the capabilities of classical computers are likely to be devices that
exploit characteristics inherent to a particular physical system, to tackle a
bespoke problem suited to those characteristics. Evidence implies that the
detection of ensembles of photons, which have propagated through a linear
optical circuit, is equivalent to sampling from a probability distribution that
is intractable to classical simulation. However, it is probable that the
complexity of this type of sampling problem means that its solution is
classically unverifiable within a feasible number of trials, and the task of
establishing correct operation becomes one of gathering sufficiently convincing
circumstantial evidence. Here, we develop scalable methods to experimentally
establish correct operation for this class of sampling algorithm, which we
implement with two different types of optical circuits for 3, 4, and 5 photons,
on Hilbert spaces of up to 50,000 dimensions. With only a small number of
trials, we establish a confidence >99% that we are not sampling from a uniform
distribution or a classical distribution, and we demonstrate a unitary specific
witness that functions robustly for small amounts of data. Like the algorithmic
operations they endorse, our methods exploit the characteristics native to the
quantum system in question. Here we observe and make an application of a
"bosonic clouding" phenomenon, interesting in its own right, where photons are
found in local groups of modes superposed across two locations. Our broad
approach is likely to be practical for all architectures for quantum
technologies where formal verification methods for quantum algorithms are
either intractable or unknown.Comment: Comments welcom
Cooperativity of membrane-protein and protein–protein interactions control membrane remodeling by epsin 1 and affects clathrin-mediated endocytosis
Membrane remodeling is a critical process for many membrane trafficking events, including clathrin-mediated endocytosis. Several molecular mechanisms for protein-induced membrane curvature have been described in some detail. Contrary, the effect that the physico-chemical properties of the membrane have on these processes is far less well understood. Here, we show that the membrane binding and curvature-inducing ENTH domain of epsin1 is regulated by phosphatidylserine (PS). ENTH binds to membranes in a PI(4,5)P2-dependent manner but only induces curvature in the presence of PS. On PS-containing membranes, the ENTH domain forms rigid homo-oligomers and assembles into clusters. Membrane binding and membrane remodeling can be separated by structure-to-function mutants. Such oligomerization mutants bind to membranes but do not show membrane remodeling activity. In vivo, they are not able to rescue defects in epidermal growth factor receptor (EGFR) endocytosis in epsin knock-down cells. Together, these data show that the membrane lipid composition is important for the regulation of protein-dependent membrane deformation during clathrin-mediated endocytosis
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