2,807 research outputs found
Coupled Two-Way Clustering Analysis of Gene Microarray Data
We present a novel coupled two-way clustering approach to gene microarray
data analysis. The main idea is to identify subsets of the genes and samples,
such that when one of these is used to cluster the other, stable and
significant partitions emerge. The search for such subsets is a computationally
complex task: we present an algorithm, based on iterative clustering, which
performs such a search. This analysis is especially suitable for gene
microarray data, where the contributions of a variety of biological mechanisms
to the gene expression levels are entangled in a large body of experimental
data. The method was applied to two gene microarray data sets, on colon cancer
and leukemia. By identifying relevant subsets of the data and focusing on them
we were able to discover partitions and correlations that were masked and
hidden when the full dataset was used in the analysis. Some of these partitions
have clear biological interpretation; others can serve to identify possible
directions for future research
A Single Atom as a Mirror of an Optical Cavity
By tightly focussing a laser field onto a single cold ion trapped in front of
a far-distant dielectric mirror, we could observe a quantum electrodynamic
effect whereby the ion behaves as the optical mirror of a Fabry-P\'erot cavity.
We show that the amplitude of the laser field is significantly altered due to a
modification of the electromagnetic mode structure around the atom in a novel
regime in which the laser intensity is already changed by the atom alone. e
propose a direct application of this system as a quantum memory for single
photons.Comment: 7 pages, 3 figures, to appear in Physical Review Letter
Effective-range approach and scaling laws for electromagnetic strength in neutron-halo nuclei
We study low-lying multipole strength in neutron-halo nuclei. The strength
depends only on a few low-energy constants: the neutron separation energy, the
asymptotic normalization coefficient of the bound state wave function, and the
scattering length that contains the information on the interaction in the
continuum. The shape of the transition probability shows a characteristic
dependence on few scaling parameters and the angular momenta. The total E1
strength is related to the root-mean-square radius of the neutron wave function
in the ground state and shows corresponding scaling properties. We apply our
approach to the E1 strength distribution of 11Be.Comment: 4 pages, 1 figure (modified), additional table, extended discussion
of example, accepted for publication in Phys. Rev. Let
Turbofan forced mixer lobe flow modeling. Part 3: Application to augment engines
Military engines frequently need large quantities of thrust for short periods of time. The addition of an augmentor can provide such thrust increases but with a penalty of increased duct length and engine weight. The addition of a forced mixer to the augmentor improves performance and reduces the penalty, as well as providing a method for siting the required flame holders. In this report two augmentor concepts are investigated: a swirl-mixer augmentor and a mixer-flameholder augmentor. Several designs for each concept are included and an experimental assessment of one of the swirl-mixer augmentors is presented
QED with a spherical mirror
We investigate the Quantum-Electro-Dynamic properties of an atomic electron
close to the focus of a spherical mirror. We first show that the spontaneous
emission and excited state level shift of the atom can be fully suppressed with
mirror-atom distances of many wavelengths. A three-dimensional theory predicts
that the spectral density of vacuum fluctuations can indeed vanish within a
volume around the atom, with the use of a far distant mirror
covering only half of the atomic emission solid angle. The modification of
these QED atomic properties is also computed as a function of the mirror size
and large effects are found for only moderate numerical apertures. We also
evaluate the long distance ground state energy shift (Casimir-Polder shift) and
find that it scales as at the focus of a hemi-spherical mirror
of radius , as opposed to the well known scaling law for an
atom at a distance from an infinite plane mirror. Our results are relevant
for investigations of QED effects, and also free space coupling to single atoms
using high-numerical aperture lenses.Comment: 12 pages, 4 figure
Effective generation of cat and kitten states
We present an effective method of coherent state superposition (cat state)
generation using single trapped ion in a Paul trap. The method is
experimentally feasible for coherent states with amplitude using
available technology. It works both in and beyond the Lamb-Dicke regime.Comment: 11 pages, 8 figure
Experimental quantum information processing with 43Ca+ ions
For quantum information processing (QIP) with trapped ions, the isotope 43Ca+
offers the combined advantages of a quantum memory with long coherence time, a
high fidelity read out and the possibility of performing two qubit gates on a
quadrupole transition with a narrow-band laser. Compared to other ions used for
quantum computing, 43Ca+ has a relatively complicated level structure. In this
paper we discuss how to meet the basic requirements for QIP and demonstrate
ground state cooling, robust state initialization and efficient read out for
the hyperfine qubit with a single 43Ca+ ion. A microwave field and a Raman
light field are used to drive qubit transitions, and the coherence times for
both fields are compared. Phase errors due to interferometric instabilities in
the Raman field generation do not limit the experiments on a time scale of 100
ms. We find a quantum information storage time of many seconds for the
hyperfine qubit.Comment: 9 pages, 10 figure
Electromagnetically Induced Transparency from a Single Atom in Free Space
We report an absorption spectroscopy experiment and the observation of
electromagnetically induced transparency from a single trapped atom. We focus a
weak and narrowband Gaussian light beam onto an optically cooled Barium ion
using a high numerical aperture lens. Extinction of this beam is observed with
measured values of up to 1.3 %. We demonstrate electromagnetically induced
transparency of the ion by tuning a strong control beam over a two-photon
resonance in a three-level lambda-type system. The probe beam extinction is
inhibited by more than 75 % due to population trapping.Comment: 4 pages, 3 figure
Super-paramagnetic clustering of yeast gene expression profiles
High-density DNA arrays, used to monitor gene expression at a genomic scale,
have produced vast amounts of information which require the development of
efficient computational methods to analyze them. The important first step is to
extract the fundamental patterns of gene expression inherent in the data. This
paper describes the application of a novel clustering algorithm,
Super-Paramagnetic Clustering (SPC) to analysis of gene expression profiles
that were generated recently during a study of the yeast cell cycle. SPC was
used to organize genes into biologically relevant clusters that are suggestive
for their co-regulation. Some of the advantages of SPC are its robustness
against noise and initialization, a clear signature of cluster formation and
splitting, and an unsupervised self-organized determination of the number of
clusters at each resolution. Our analysis revealed interesting correlated
behavior of several groups of genes which has not been previously identified
Quasirelativistic quasilocal finite wave-function collapse model
A Markovian wave function collapse model is presented where the
collapse-inducing operator, constructed from quantum fields, is a manifestly
covariant generalization of the mass density operator utilized in the
nonrelativistic Continuous Spontaneous Localization (CSL) wave function
collapse model. However, the model is not Lorentz invariant because two such
operators do not commute at spacelike separation, i.e., the time-ordering
operation in one Lorentz frame, the "preferred" frame, is not the time-ordering
operation in another frame. However, the characteristic spacelike distance over
which the commutator decays is the particle's Compton wavelength so, since the
commutator rapidly gets quite small, the model is "almost" relativistic. This
"QRCSL" model is completely finite: unlike previous, relativistic, models, it
has no (infinite) energy production from the vacuum state.
QRCSL calculations are given of the collapse rate for a single free particle
in a superposition of spatially separated packets, and of the energy production
rate for any number of free particles: these reduce to the CSL rates if the
particle's Compton wavelength is small compared to the model's distance
parameter. One motivation for QRCSL is the realization that previous
relativistic models entail excitation of nuclear states which exceeds that of
experiment, whereas QRCSL does not: an example is given involving quadrupole
excitation of the Ge nucleus.Comment: 10 pages, to be published in Phys. Rev.
- …