624 research outputs found
The OLYMPUS Internal Hydrogen Target
An internal hydrogen target system was developed for the OLYMPUS experiment
at DESY, in Hamburg, Germany. The target consisted of a long, thin-walled,
tubular cell within an aluminum scattering chamber. Hydrogen entered at the
center of the cell and exited through the ends, where it was removed from the
beamline by a multistage pumping system. A cryogenic coldhead cooled the target
cell to counteract heating from the beam and increase the density of hydrogen
in the target. A fixed collimator protected the cell from synchrotron radiation
and the beam halo. A series of wakefield suppressors reduced heating from beam
wakefields. The target system was installed within the DORIS storage ring and
was successfully operated during the course of the OLYMPUS experiment in 2012.
Information on the design, fabrication, and performance of the target system is
reported.Comment: 9 pages, 13 figure
`TSMI:a CEN/TC51 standard for time specific problems in healthcare informatics and telematics'
Evaluation of early and late presentation of patients with ocular mucous membrane pemphigoid to two major tertiary referral hospitals in the United Kingdom
PURPOSE: Ocular mucous membrane pemphigoid (OcMMP) is a sight-threatening autoimmune disease in which referral to specialists units for further management is a common practise. This study aims to describe referral patterns, disease phenotype and management strategies in patients who present with either early or established disease to two large tertiary care hospitals in the United Kingdom.\ud
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PATIENTS AND METHODS: In all, 54 consecutive patients with a documented history of OcMMP were followed for 24 months. Two groups were defined: (i) early-onset disease (EOD:<3 years, n=26, 51 eyes) and (ii) established disease (EstD:>5 years, n=24, 48 eyes). Data were captured at first clinic visit, and at 12 and 24 months follow-up. Information regarding duration, activity and stage of disease, visual acuity (VA), therapeutic strategies and clinical outcome were analysed.\ud
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RESULTS: Patients with EOD were younger and had more severe conjunctival inflammation (76% of inflamed eyes) than the EstD group, who had poorer VA (26.7%=VA<3/60, P<0.01) and more advanced disease. Although 40% of patients were on existing immunosuppression, 48% required initiation or switch to more potent immunotherapy. In all, 28% (14) were referred back to the originating hospitals for continued care. Although inflammation had resolved in 78% (60/77) at 12 months, persistence of inflammation and progression did not differ between the two phenotypes. Importantly, 42% demonstrated disease progression in the absence of clinically detectable inflammation.\ud
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CONCLUSIONS: These data highlight that irrespective of OcMMP phenotype, initiation or escalation of potent immunosuppression is required at tertiary hospitals. Moreover, the conjunctival scarring progresses even when the eye remains clinically quiescent. Early referral to tertiary centres is recommended to optimise immunosuppression and limit long-term ocular damage.\ud
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A helical-shape scintillating fiber trigger and tracker system for the DarkLight experiment and beyond
The search for new physics beyond the Standard Model has interesting
possibilities at low energies. For example, the recent 6.8 anomaly
reported in the invariant mass of pairs from nuclear
transitions and the discrepancy between predicted and measured values of muon
g-2 give strong motivations for a protophobic fifth-force model. At low
energies, the electromagnetic interaction is well understood and produces
straightforward final states, making it an excellent probe of such models.
However, to achieve the required precision, an experiment must address the
substantially higher rate of electromagnetic backgrounds. In this paper, we
present the results of simulation studies of a trigger system, motivated by the
DarkLight experiment, using helical-shape scintillating fibers in a solenoidal
magnetic field to veto electron-proton elastic scattering and the associated
radiative processes. We also assess the performance of a tracking detector for
lepton final states using scintillating fibers in the same setup
The size of the proton - closing in on the radius puzzle
We analyze the recent electron-proton scattering data from Mainz using a
dispersive framework that respects the constraints from analyticity and
unitarity on the nucleon structure. We also perform a continued fraction
analysis of these data. We find a small electric proton charge radius, r_E^p =
0.84_{-0.01}^{+0.01} fm, consistent with the recent determination from muonic
hydrogen measurements and earlier dispersive analyses. We also extract the
proton magnetic radius, r_M^p = 0.86_{-0.03}^{+0.02} fm, consistent with
earlier determinations based on dispersion relations.Comment: 4 pages, 2 figures, fit improved, small modifications, section on
continued fractions modified, conclusions on the proton charge radius
unchanged, version accepted for publication in European Physical Journal
Environmental changes and violent conflict
This letter reviews the scientific literature on whether and how environmental changes affect the risk of violent conflict. The available evidence from qualitative case studies indicates that environmental stress can contribute to violent conflict in some specific cases. Results from quantitative large-N studies, however, strongly suggest that we should be careful in drawing general conclusions. Those large-N studies that we regard as the most sophisticated ones obtain results that are not robust to alternative model specifications and, thus, have been debated. This suggests that environmental changes may, under specific circumstances, increase the risk of violent conflict, but not necessarily in a systematic way and unconditionally. Hence there is, to date, no scientific consensus on the impact of environmental changes on violent conflict. This letter also highlights the most important challenges for further research on the subject. One of the key issues is that the effects of environmental changes on violent conflict are likely to be contingent on a set of economic and political conditions that determine adaptation capacity. In the authors' view, the most important indirect effects are likely to lead from environmental changes via economic performance and migration to violent conflict. © 2012 IOP Publishing Ltd
Search for Light Gauge Bosons of the Dark Sector at the Mainz Microtron
A new exclusion limit for the electromagnetic production of a light U(1)
gauge boson {\gamma}' decaying to e^+e^- was determined by the A1 Collaboration
at the Mainz Microtron. Such light gauge bosons appear in several extensions of
the standard model and are also discussed as candidates for the interaction of
dark matter with standard model matter. In electron scattering from a heavy
nucleus, the existing limits for a narrow state coupling to e^+e^- were reduced
by nearly an order of magnitude in the range of the lepton pair mass of 210
MeV/c^2 < m_e^+e^- < 300 MeV/c^2. This experiment demonstrates the potential of
high current and high resolution fixed target experiments for the search for
physics beyond the standard model.Comment: 4 pages, 7 figure
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