Exploring the differences between forward osmosis and reverse osmosis fouling

A comparison of alginate fouling in forward osmosis (FO) with that in reverse osmosis (RO) was made. A key experimental finding, corroborated by membrane autopsies, was that FO is essentially more prone to fouling than RO, which is opposite to a common claim in the literature where deductions on fouling are often based solely on the water flux profiles. Our theoretical analysis shows that, due to a decrease in the intensity of internal concentration polarization (ICP), and thus an increase in the effective osmotic driving force during FO fouling tests, the similarity of experimental water flux profiles for FO and RO is in accordance with there being greater fouling in FO than RO. The specific foulant resistance for FO was also found to be greater than that for RO. Possible explanations are discussed and these include the influence of reverse solute diffusion from draw solution. Whilst this explanation regarding specific foulant resistance is dependent on the draw solution properties, the finding of greater overall foulant accumulation in FO is considered to be a general finding. Additionally, the present study did not find evidence that hydraulic pressure in RO plays a critical role in foulant layer compaction. Overall this study demonstrated that although FO has higher fouling propensity, it offers superior water flux stability against fouling. For certain practical applications this resilience may be important

Energy management of virtual power plant considering distributed generation sizing and pricing

UID/EMS/00667/2019The energy management of virtual power plants faces some fundamental challenges that make it complicated compared to conventional power plants, such as uncertainty in production, consumption, energy price, and availability of network components. Continuous monitoring and scaling of network gain status, using smart grids provides valuable instantaneous information about network conditions such as production, consumption, power lines, and network availability. Therefore, by creating a bidirectional communication between the energy management system and the grid users such as producers or energy applicants, it will afford a suitable platform to develop more efficient vector of the virtual power plant. The paper is treated with optimal sizing of DG units and the price of their electricity sales to achieve security issues and other technical considerations in the system. The ultimate goal in this study to determine the active demand power required to increase system loading capability and to withstand disturbances. The effect of different types of DG units in simulations is considered and then the efficiency of each equipment such as converters, wind turbines, electrolyzers, etc., is achieved to minimize the total operation cost and losses, improve voltage profiles, and address other security issues and reliability. The simulations are done in three cases and compared with HOMER software to validate the ability of proposed model.publishersversionpublishe

Big Data and Predictive Analytics in Malaysian Micro, Small and Medium Businesses

Innovative technologies such as big data and predictive analytics are facilitating a global revolution in operational management. The present study aims to investigate the extent of their adoption among micro-, small and medium enterprises. The context of choice is Malaysia—a growing economy hosting some of the relatively more technologically advanced enterprises in ASEAN union. The research plan of the present paper pursued three objectives. First, we aimed to identify the general rate of adoption of BDPA. Second, we explored the most common uses of this set of innovations in Malaysian micro-, small, and medium enterprises. Third, we strove to abstract the antecedents and consequences of BDPA in micro-, small, and large firms in the manufacturing and service sectors. We discovered that BDPA are almost never used to outsource suppliers or to optimise spending and purchasing. Conversely, the most frequent applications of BDPA are in customer relationship management and in warehouse and operations improvement. Moreover, we smaller firms are more resilient to the challenges of adopting BDPA than their smaller and larger counterparts. Thus, this paper presents a snapshot of the BDPA dissemination in the micro-, small and medium ecosystem in Malaysia in 2021, while exploring opportunities for the future development and dissemination of this set of innovations

Experimental Insights into the Coupling of Methane Combustion and Steam Reforming in a Catalytic Plate Reactor in Transient Mode

The microstructured reactor concept is very promising technology to develop a compact reformer for distributed hydrogen generation. In this work, a catalytic plate reactor (CPR) is developed and investigated for the coupling of methane combustion (MC) and methane steam reforming (MSR) over Pt/Al2O3-coated microchannels in cocurrent and counter-current modes in transient experiments during start-up. A three-dimensional (3D) computational fluid dynamics (CFD) simulation shows uniform velocity and pressure distribution profiles in microchannels. For a channel velocity from 5.1 to 57.3 m/s in the combustor, the oxidation of methane is complete and self-sustainable without explosion, blow-off, or extinction; nevertheless, flashbacks are observed in counter-current mode. In the reformer, the maximum methane conversion is 84.9% in cocurrent mode, slightly higher than that of 80.2% in counter-current mode at a residence time of 33 ms, but at the cost of three times higher energy input in the combustor operating at ∼1000 °C. Nitric oxide (NO) is not identified in combustion products, but nitrous oxide (N2O) is a function of coupling mode and forms significantly in cocurrent mode. This research would be helpful to establish the start-up strategy and environmental impact of compact reformers on a small scale

Reverse osmosis and forward osmosis fouling: a comparison

Our previously reported exploration (Journal of Membrane Science 565 (2018) 241–253) on the differences between fouling in reverse osmosis (RO) and forward osmosis (FO), used alginate as a foulant with initial conditions that ensured that the starting fluxes were the same. That study found that for a cellulose triacetate (CTA) membrane the extent of fouling, based on the analysis of foulant resistance, was greater when the membrane was part of a FO system. Herein, using the same methodology, results for a thin film composite membrane with alginate as the foulant are presented and these confirm the same general conclusion namely that the extent of foulant accumulation in FO mode is more severe than in RO mode. Furthermore the specific fouling resistance with alginate fouling in FO is more than for RO. However examining the overall operation including cleaning as well as fouling, this study suggests that FO operation is potentially less sensitive to fouling phenomena than RO for similar feed materials. This is due to the driving force compensation coming from a changing level of ICP. Some preliminary work including that with silica particles is also reported

Efficacy of single pass UVC air treatment for the inactivation of coronavirus, MS2 coliphage and Staphylococcus aureus bioaerosols

Publication history: Accepted - 20 April 2022; Published online - 26 April 2022There is strong evidence that SARS-CoV-2 is spread predominantly by airborne transmission, with high viral loads released into the air as respiratory droplets and aerosols from the infected subject. The spread and persistence of SARS-CoV-2 in diverse indoor environments reinforces the urgent need to supplement distancing and PPE based approaches with effective engineering measures for microbial decontamination – thereby addressing the significant risk posed by aerosols. We hypothesized that a portable, single-pass UVC air treatment device (air flow 1254 L/min) could effectively inactivate bioaerosols containing bacterial and viral indicator organisms, and coronavirus without reliance on filtration technology, at reasonable scale. Robust experiments demonstrated UVC dose dependent inactivation of Staphylococcus aureus (UV rate constant (k) = 0.098 m2/J) and bacteriophage MS2, with up to 6-log MS2 reduction achieved in a single pass through the system (k = 0.119 m2/J). The inclusion of a PTFE diffuse reflector increased the effective UVC dose by up to 34% in comparison to a standard Al foil reflector (with identical lamp output), resulting in significant additional pathogen inactivation (1-log S. aureus and MS2, p < 0.001). Complete inactivation of bovine coronavirus bioaerosols was demonstrated through tissue culture infectivity (2.4-log reduction) and RT-qPCR analysis – confirming single pass UVC treatment to effectively deactivate coronavirus to the limit of detection of the culture-based method. Scenario-based modelling was used to investigate the reduction in risk of airborne person-to-person transmission based upon a single infected subject within the small room. Use of the system providing 5 air changes per hour was shown to significantly reduce airborne viral load and maintain low numbers of RNA copies when the infected subject remained in the room, reducing the risk of airborne pathogen transmission to other room users. We conclude that the application of single-pass UVC systems (without reliance on HEPA filtration) could play a critical role in reducing the risk of airborne pathogen transfer, including SARS-CoV2, in locations where adequate fresh air ventilation cannot be implemented.This research was partly funded through the Invest Northern Ireland Innovation Voucher Programme (IV130218200 and IV130232906). We are grateful to the Global Challenges Research Fund (GCRF) UK Research and Innovation (SAFEWATER; EPSRC Grant Reference EP/P032427/1) for supporting Mr Arsalan Afkhami, Dr William J Snelling and Dr Jeremy W.J. Hamilton. Research at AFBI is funded by US-Ireland Research and Development Partnership in Agriculture grants BRDC-Seq and BRDC-URTMVP. We wish to thank Jonathan McMaw at AFBI for acquisition of images

Molecular characterization of a Leishmania donovanii cDNA clone with similarity to human 20S proteasome a-type subunit1The sequence data reported in this paper have been submitted to EMBL/GenBank and DDJB data libraries under accession No. AF088882.1

AbstractUsing plasma from patients infected or previously infected with Leishmania donovanii, we isolated a L. donovanii cDNA clone with similarity to the proteasome a-type subunit from humans and other eukaryotes. The cDNA clone, designated LePa, was DNA sequenced and Northern blot analysis of L. donovanii poly(A+)mRNA indicated the isolation of a full length cDNA clone with a transcript size of 1.9 kb. The expressed recombinant LePa fusion protein induced proliferation of peripheral blood mononuclear cells in one out of seven patients who had suffered from visceral leishmaniasis. Plasma from 16 out of 25 patients with visceral leishmaniasis and four out of 18 patients with cutaneous leishmaniasis contained IgG antibodies which reacted with the purified LePa fusion protein as evaluated in an ELISA. The LePa DNA sequence was inserted into an eukaryotic expression vector and Balb/c mice were vaccinated. DNA vaccination of Balb/c mice with LePa generated an initial significant reduction in lesion size after challenge

CRT-700.05 Impella Utilization in High-Risk Percutaneous Coronary Intervention Mitigates the Risks of Procedural and Clinical Adverse Events Independent of Left Ventricular Ejection Fraction: The Protect III Study

Background: Left ventricular (LV) dysfunction is associated with an increased risk of adverse events in patients undergoing percutaneous coronary intervention (PCI). However, the impact of LV ejection fraction (LVEF) on the outcomes of Impella-supported high-risk PCI (HRPCI) is unknown. Methods: Patients enrolled in the prospective, multicenter, and observational PROTECT III study from March 2017 to March 2020 who underwent Impella-supported HRPCI at the operator’s discretion (non-cardiogenic shock). Patients were divided into three tertiles (T) based on baseline LVEF: T1 (the lowest), T2, and T3 (the highest). The primary outcome is the rate of 90-day major adverse cardiac and cerebrovascular events (MACCE), defined as the composite of all-cause death, myocardial infarction, stroke/transient ischemic attack, and repeated revascularization as adjudicated by an independent CEC. Results: Of 1237 patients, 940 with available baseline LVEF were analyzed. T1 included 353 patients (mean LVEF 19.6±4.7), T2 included 274 patients (mean LVEF 32.2±3.5), and T3 included 313 patients (mean LVEF 52.6±9.2). Patients in the higher tertiles were older, more likely to be females, presented more with acute coronary syndrome, and had more frequent left main disease. Also, severely calcified lesions and atherectomy utilization were more frequent in the higher tertiles. The rates of 90-day MACCE were comparable across all tertiles. Furthermore, PCI-related complications and 1-year mortality were also comparable (Table). After multivariable adjustment, 90-day MACCE was not significantly different between the LVEF tertiles (p=0.32). Conclusion: In patients with HRPCI supported by Impella, the rates of in-hospital adverse events, PCI-related complications, 90-day MACCE, and 1-year mortality were comparable among the different LVEF tertiles

Transgenic expression of the dicotyledonous pattern recognition receptor EFR in rice leads to ligand-dependent activation of defense responses

Plant plasma membrane localized pattern recognition receptors (PRRs) detect extracellular pathogen-associated molecules. PRRs such as Arabidopsis EFR and rice XA21 are taxonomically restricted and are absent from most plant genomes. Here we show that rice plants expressing EFR or the chimeric receptor EFR::XA21, containing the EFR ectodomain and the XA21 intracellular domain, sense both Escherichia coli- and Xanthomonas oryzae pv. oryzae (Xoo)-derived elf18 peptides at sub-nanomolar concentrations. Treatment of EFR and EFR::XA21 rice leaf tissue with elf18 leads to MAP kinase activation, reactive oxygen production and defense gene expression. Although expression of EFR does not lead to robust enhanced resistance to fully virulent Xoo isolates, it does lead to quantitatively enhanced resistance to weakly virulent Xoo isolates. EFR interacts with OsSERK2 and the XA21 binding protein 24 (XB24), two key components of the rice XA21-mediated immune response. Rice-EFR plants silenced for OsSERK2, or overexpressing rice XB24 are compromised in elf18-induced reactive oxygen production and defense gene expression indicating that these proteins are also important for EFR-mediated signaling in transgenic rice. Taken together, our results demonstrate the potential feasibility of enhancing disease resistance in rice and possibly other monocotyledonous crop species by expression of dicotyledonous PRRs. Our results also suggest that Arabidopsis EFR utilizes at least a subset of the known endogenous rice XA21 signaling components