68 research outputs found
Ultrasensitive force detection with a nanotube mechanical resonator
Since the advent of atomic force microscopy, mechanical resonators have been
used to study a wide variety of phenomena, such as the dynamics of individual
electron spins, persistent currents in normal metal rings, and the Casimir
force. Key to these experiments is the ability to measure weak forces. Here, we
report on force sensing experiments with a sensitivity of 12 zN Hz^(-1/2) at a
temperature of 1.2 K using a resonator made of a carbon nanotube. An
ultra-sensitive method based on cross-correlated electrical noise measurements,
in combination with parametric downconversion, is used to detect the
low-amplitude vibrations of the nanotube induced by weak forces. The force
sensitivity is quantified by applying a known capacitive force. This detection
method also allows us to measure the Brownian vibrations of the nanotube down
to cryogenic temperatures. Force sensing with nanotube resonators offers new
opportunities for detecting and manipulating individual nuclear spins as well
as for magnetometry measurements.Comment: Early version. To be published in Nature Nanotechnolog
Electrical and thermoelectrical transport in Dirac fermions through a quantum dot
We investigate the conductance and thermopower of massless Dirac fermions
through a quantum dot using a pseudogap Anderson model in the non-crossing
approximation. When the Fermi level is at the Dirac point, the conductance has
a cusp where the thermopower changes its sign. When the Fermi level is away
from the Dirac point, the Kondo temperature illustrates a quantum impurity
transition between an asymmetric strong coupling Kondo state and a localized
moment state. The conductance shows a peak near this transition and reaches the
unitary limit at low temperatures. The magnitude of the thermopower exceeds
, and the thermoelectric figure of merit exceeds unity.Comment: 5 pages, 4 figure
Statistical signatures of critical behavior in small systems
The cluster distributions of different systems are examined to search for
signatures of a continuous phase transition. In a system known to possess such
a phase transition, both sensitive and insensitive signatures are present;
while in systems known not to possess such a phase transition, only insensitive
signatures are present. It is shown that nuclear multifragmentation results in
cluster distributions belonging to the former category, suggesting that the
fragments are the result of a continuous phase transition.Comment: 31 pages, two columns with 30 figure
Geometric phases and Bloch sphere constructions for SU(N), with a complete description of SU(4)
A two-sphere ("Bloch" or "Poincare") is familiar for describing the dynamics
of a spin-1/2 particle or light polarization. Analogous objects are derived for
unitary groups larger than SU(2) through an iterative procedure that constructs
evolution operators for higher-dimensional SU in terms of lower-dimensional
ones. We focus, in particular, on the SU(4) of two qubits which describes all
possible logic gates in quantum computation. For a general Hamiltonian of SU(4)
with 15 parameters, and for Hamiltonians of its various sub-groups so that
fewer parameters suffice, we derive Bloch-like rotation of unit vectors
analogous to the one familiar for a single spin in a magnetic field. The
unitary evolution of a quantal spin pair is thereby expressed as rotations of
real vectors. Correspondingly, the manifolds involved are Bloch two-spheres
along with higher dimensional manifolds such as a four-sphere for the SO(5)
sub-group and an eight-dimensional Grassmannian manifold for the general SU(4).
This latter may also be viewed as two, mutually orthogonal, real
six-dimensional unit vectors moving on a five-sphere with an additional phase
constraint.Comment: 9 page
Properties of Graphene: A Theoretical Perspective
In this review, we provide an in-depth description of the physics of
monolayer and bilayer graphene from a theorist's perspective. We discuss the
physical properties of graphene in an external magnetic field, reflecting the
chiral nature of the quasiparticles near the Dirac point with a Landau level at
zero energy. We address the unique integer quantum Hall effects, the role of
electron correlations, and the recent observation of the fractional quantum
Hall effect in the monolayer graphene. The quantum Hall effect in bilayer
graphene is fundamentally different from that of a monolayer, reflecting the
unique band structure of this system. The theory of transport in the absence of
an external magnetic field is discussed in detail, along with the role of
disorder studied in various theoretical models. We highlight the differences
and similarities between monolayer and bilayer graphene, and focus on
thermodynamic properties such as the compressibility, the plasmon spectra, the
weak localization correction, quantum Hall effect, and optical properties.
Confinement of electrons in graphene is nontrivial due to Klein tunneling. We
review various theoretical and experimental studies of quantum confined
structures made from graphene. The band structure of graphene nanoribbons and
the role of the sublattice symmetry, edge geometry and the size of the
nanoribbon on the electronic and magnetic properties are very active areas of
research, and a detailed review of these topics is presented. Also, the effects
of substrate interactions, adsorbed atoms, lattice defects and doping on the
band structure of finite-sized graphene systems are discussed. We also include
a brief description of graphane -- gapped material obtained from graphene by
attaching hydrogen atoms to each carbon atom in the lattice.Comment: 189 pages. submitted in Advances in Physic
Hellmann-Feynman theorem and fluctuation-correlation analysis of the Calogero-Sutherland model
Exploiting the results of the exact solution for the ground state of the
one-dimensional spinless quantum gas of Fermions and impenetrable Bosons with
the mu/x_{ij}^2 particle-particle interaction, the Hellmann-Feynman theorem
yields mutually compensating divergences of both the kinetic and the
interaction energy in the limiting case mu to -1/4. These divergences result
from the peculiar behavior of both the momentum distribution (for large
momenta) and the pair density (for small inter-particle separation). The
available analytical pair densities for mu=-1/4, 0, and 2 allow to analyze
particle-number fluctuations. They are suppressed by repulsive interaction
(mu>0), enhanced by attraction (mu<0), and may therefore measure the kind and
strength of correlation. Other recently proposed purely quantum-kinematical
measures of the correlation strength arise from the small-separation behavior
of the pair density or - for Fermions - from the non-idempotency of the
momentum distribution and its large-momenta behavior. They are compared with
each other and with reference-free, short-range correlation-measuring ratios of
the kinetic and potential energies.Comment: 30 pages, 9 figures, revised version, short version appeared as PRB
62, 15279-15282 (2000
PSSA-2, a Membrane-Spanning Phosphoprotein of Trypanosoma brucei, Is Required for Efficient Maturation of Infection
The coat of Trypanosoma brucei consists mainly of glycosylphosphatidylinositol-anchored proteins that are present in several million copies and are characteristic of defined stages of the life cycle. While these major components of the coats of bloodstream forms and procyclic (insect midgut) forms are well characterised, very little is known about less abundant stage-regulated surface proteins and their roles in infection and transmission. By creating epitope-tagged versions of procyclic-specific surface antigen 2 (PSSA-2) we demonstrated that it is a membrane-spanning protein that is expressed by several different life cycle stages in tsetse flies, but not by parasites in the mammalian bloodstream. In common with other membrane-spanning proteins in T. brucei, PSSA-2 requires its cytoplasmic domain in order to exit the endoplasmic reticulum. Correct localisation of PSSA-2 requires phosphorylation of a cytoplasmic threonine residue (T305), a modification that depends on the presence of TbMAPK4. Mutation of T305 to alanine (T305A) has no effect on the localisation of the protein in cells that express wild type PSSA-2. In contrast, this protein is largely intracellular when expressed in a null mutant background. A variant with a T305D mutation gives strong surface expression in both the wild type and null mutant, but slows growth of the cells, suggesting that it may function as a dominant negative mutant. The PSSA-2 null mutant exhibits no perceptible phenotype in culture and is fully competent at establishing midgut infections in tsetse, but is defective in colonising the salivary glands and the production of infectious metacyclic forms. Given the protein's structure and the effects of mutation of T305 on proliferation and localisation, we postulate that PSSA-2 might sense and transmit signals that contribute to the parasite's decision to divide, differentiate or migrate
Gigahertz quantized charge pumping in graphene quantum dots
Single electron pumps are set to revolutionize electrical metrology by
enabling the ampere to be re-defined in terms of the elementary charge of an
electron. Pumps based on lithographically-fixed tunnel barriers in mesoscopic
metallic systems and normal/superconducting hybrid turnstiles can reach very
small error rates, but only at MHz pumping speeds corresponding to small
currents of the order 1 pA. Tunable barrier pumps in semiconductor structures
have been operated at GHz frequencies, but the theoretical treatment of the
error rate is more complex and only approximate predictions are available.
Here, we present a monolithic, fixed barrier single electron pump made entirely
from graphene. We demonstrate pump operation at frequencies up to 1.4 GHz, and
predict the error rate to be as low as 0.01 parts per million at 90 MHz.
Combined with the record-high accuracy of the quantum Hall effect and proximity
induced Josephson junctions, accurate quantized current generation brings an
all-graphene closure of the quantum metrological triangle within reach.
Envisaged applications for graphene charge pumps outside quantum metrology
include single photon generation via electron-hole recombination in
electrostatically doped bilayer graphene reservoirs, and for readout of
spin-based graphene qubits in quantum information processing.Comment: 13 pages, 11 figures, includes supplementary informatio
Diverse Roles and Interactions of the SWI/SNF Chromatin Remodeling Complex Revealed Using Global Approaches
A systems understanding of nuclear organization and events is critical for determining how cells divide, differentiate, and respond to stimuli and for identifying the causes of diseases. Chromatin remodeling complexes such as SWI/SNF have been implicated in a wide variety of cellular processes including gene expression, nuclear organization, centromere function, and chromosomal stability, and mutations in SWI/SNF components have been linked to several types of cancer. To better understand the biological processes in which chromatin remodeling proteins participate, we globally mapped binding regions for several components of the SWI/SNF complex throughout the human genome using ChIP-Seq. SWI/SNF components were found to lie near regulatory elements integral to transcription (e.g. 5′ ends, RNA Polymerases II and III, and enhancers) as well as regions critical for chromosome organization (e.g. CTCF, lamins, and DNA replication origins). Interestingly we also find that certain configurations of SWI/SNF subunits are associated with transcripts that have higher levels of expression, whereas other configurations of SWI/SNF factors are associated with transcripts that have lower levels of expression. To further elucidate the association of SWI/SNF subunits with each other as well as with other nuclear proteins, we also analyzed SWI/SNF immunoprecipitated complexes by mass spectrometry. Individual SWI/SNF factors are associated with their own family members, as well as with cellular constituents such as nuclear matrix proteins, key transcription factors, and centromere components, implying a ubiquitous role in gene regulation and nuclear function. We find an overrepresentation of both SWI/SNF-associated regions and proteins in cell cycle and chromosome organization. Taken together the results from our ChIP and immunoprecipitation experiments suggest that SWI/SNF facilitates gene regulation and genome function more broadly and through a greater diversity of interactions than previously appreciated
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Copia digital. Madrid : Ministerio de Educación, Cultura y Deporte, 201
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