Analysis of contents about sexuality and human reproduction in school textbooks in Spain

Objectives: The spread of sexually transmitted infections (STI) in adolescents and teenage pregnancy rates are increasing. A decrease in the average age of youth’s first sexual experience is also being noted. Sexual education programs in schools have an important role to play in addressing these issues. The objective of this study is to analyze the content of textbooks in the area of sexuality and human reproduction in order to evaluate the extent to which these textbooks promote healthy reproductive life styles, as well as risk behavior avoidance among the adolescent students. Study design: Descriptive study of school textbooks content. Methods: The study sample consisted of 12 textbooks (about 80% of all the textbooks) used in Spanish secondary school and edited in 2002. A content analysis evaluated the extent to which these books demonstrated reliable scientific information about: a) condom effectiveness; b) consequences, prevention, and treatment of STI; c) family planning methods; d) Assisted reproductive technologies and e) the promotion of healthy reproductive lifestyles. Results: All textbooks presented inaccurate information in the areas studied. Two hundred and eighty one quotes were identified that facilitated an incomplete perception of sexuality or enabled risky behavior. An average of 12.6 incorrect messages was identified in each textbook. Conclusions: The textbooks examined are neither appropriate nor comprehensive enough for adolescent education on issues of sexuality. Results suggest a need for alternative textbooks based on better scientific evidence. It is essential that textbooks empower adolescents to make healthy decisions through the promotion of useful life skills that provide a more integrated concept of sexuality. In any case, there is a need for approaches to sexual education to integrate values commonly held by parents of the youth that use such texts

La educación sexual en los textos escolares españoles: evaluación de un texto alternativo

Junto al aumento de la utilización de preservativos, asistimos también al aumento de la transmisión de infecciones de transmisión sexual, al adelanto en la edad de inicio de relaciones sexuales y al aumento de embarazos en adolescentes. En este sentido cobra especial importancia la educación sexual recibida en el último tramo de la educación obligatoria. Es importante, desde el punto de vista de la Salud Pública, desarrollar contenidos que permitan al alumno adquirir habilidades sociales que le ayuden a tomar decisiones más libres e informadas encaminadas a retrasar el inicio de las relaciones sexuales. En este trabajo se presentan los resultados de la evaluación comparativa sobre los contenidos de los libros escolares del área de Biología de 3º de la ESO en su capítulo sobre sexualidad y reproducción humana con un texto escolar alternativo. Se evalúa si posibilitan la consecución de los objetivos educativos señalados en el currículo y si promocionan estilos de vida saludables que lleguen a prevenir conductas de riesgo. ------------------------Together with the increase of condom use, the spread of sexually transmitted infections, earlier ages of sexual debut and pregnancies in teenagers are also increasing. Sexual education in schools plays an important role. It is therefore important, from a public health point of view, to develop materials with contents that can help students acquire the life skills that will enable them to make free and informed decisions concerning sexuality. In this study the results of a comparative evaluation of different school texts with an alternative we have elaborated for the area of sexuality and human reproduction are presented. The extent to which these books achieve official educational objectives, promote healthy life styles and convey information enabling the prevention of risky sexual behaviours was evaluated

Adapting and validating the Hospital Survey on Patient Safety Culture (HSOPS) for nursing students (HSOPS-NS): A new measure of Patient Safety Climate

Background: Patient Safety Culture and Patient Safety Climate (PSC) are different factors. PSC is the shared perception that is held within a hospital''s area or unit at a specific moment in time. This measure is necessary for designing activities for promoting and improving safety. It must include the perception of all the agents involved, including future nurses throughout their patient safety education. Objectives: The aim was to adapt and validate a new version of the Hospital Survey on Patient Safety Culture (HSOPS), targeted specifically at nursing students. It provides a new comprehensive and more complete measure of PSC that contributes to improving patient safety. Methods: Data were obtained from 654 undergraduate and postgraduate nursing students. PSC was tested using factor analyses and structural equation modeling. In order to facilitate the improvement of PSC, we examined differences in climate strength across different academic groups using the Rwg(j) and ICC measures of inter-rater agreement. Results: Factor analyses confirmed a five-factor solution that explained between 52.45% and 54.75% of the variance. The model was found to have adequate fit ¿ 2 (5) = 14.333, p =.014; CFI = 0.99; RMSEA = 0.05. Cronbach''s alphas for PSC were between 0.74 and 0.77. “Teamwork within units” was the highest rated dimension, and “Staffing” the lowest rated. Medium-to-high scores were obtained for PSC. The median of Rwg (j) was high in the five dimensions of the PSC survey, supporting the idea of shared climate perceptions (0.81–0.96) among undergraduate and postgraduate nursing students. Conclusions: HSOPS-NS is a useful and versatile tool for measuring the level and strength of PSC. It screens knowledge regarding patient safety in clinical practice placements and compares nursing students’ perceptions of the strength of PSC. Weaknesses perceived in relation to PSC help implement changes in patient safety learning

A Review of ENSO Influence on the North Atlantic. A Non-Stationary Signal

ReviewThe atmospheric seasonal cycle of the North Atlantic region is dominated by meridional movements of the circulation systems: from the tropics, where the West African Monsoon and extreme tropical weather events take place, to the extratropics, where the circulation is dominated by seasonal changes in the jetstream and extratropical cyclones. Climate variability over the North Atlantic is controlled by various mechanisms. Atmospheric internal variability plays a crucial role in the mid-latitudes. However, El Niño-Southern Oscillation (ENSO) is still the main source of predictability in this region situated far away from the Pacific. Although the ENSO influence over tropical and extra-tropical areas is related to different physical mechanisms, in both regions this teleconnection seems to be non-stationary in time and modulated by multidecadal changes of the mean flow. Nowadays, long observational records (greater than 100 years) and modeling projects (e.g., CMIP) permit detecting non-stationarities in the influence of ENSO over the Atlantic basin, and further analyzing its potential mechanisms. The present article reviews the ENSO influence over the Atlantic region, paying special attention to the stability of this teleconnection over time and the possible modulators. Evidence is given that the ENSO–Atlantic teleconnection is weak over the North Atlantic. In this regard, the multidecadal ocean variability seems to modulate the presence of teleconnections, which can lead to important impacts of ENSO and to open windows of opportunity for seasonal predictability.We thank the Climatic Research Unit (CRU), the National Centers for Environmental Prediction (NCEP), the Met Office Hadley Centre and the US National Hurricane Center (NHC) for the Land Precipitation, reanalysis, SST and HURDAT2 datasets, respectively. Belen Rodríguez-Fonseca, Roberto Suárez-Moreno, Jorge López-Parages, Iñigo Gómara, Elsa Mohino, Teresa Losada and Antonio Castaño-Tierno are supported by the research projects PREFACE (EUFP7/2007-2013 Grant Agreement 603521) and MULCLIVAR (CGL2012-38923-C02-01-Spanish Ministry of Economy and Competitiveness). Blanca Ayarzagüena is supported by the Natural Environment Research Council (grant number NE/M006123/1). Julián Villamayor is granted through a scholarship from the MICINN—Spanish government (BES-2013-063821

Analysis of HIV-1 Fusion Peptide inhibition by synthetic peptides from E1 protein of GB virus C

The aim of this study was to identify proteins that could inhibit the activity of the peptide sequence representing the N-terminal of the surface protein gp41 of HIV, corresponding to the fusion peptide of the virus (HIV-1 FP). To do this we synthesized and studied 58 peptides corresponding to the envelope protein E1 of the hepatitis G virus (GBV-C). Five of the E1 synthetic peptides: NCCAPEDIGFCLEGGCLV (P7), APEDIGFCLEGGCLVALG (P8), FCLEGGCL VALGCTICTD (P10), QAGLAVRPGKSAAQLVGE (P18) and AQLVGELGSLYGPLSVSA (P22) were capable of inhibiting the leakage of vesicular contents caused by HIV-1 FP. A series of experiments were carried out to determine how these E1 peptides interact with HIV-1 FP. Our studies analyzed the interactions with and without the presence of lipid membranes. Isothermal titration calorimetry revealed that the binding of P7, P18 and P22 peptides to HIV-1 FP is strongly endothermic, and that binding is entropy-driven. Gibbs energy for the process indicates a spontaneous binding between E1 peptides and HIV-1 FP. Moreover, confocal microscopy of Giant Unilamellar Vesicles revealed that the disruption of the lipid bilayer by HIV-1 FP alone was inhibited by the presence of any of the five selected peptides. Our results highlight that these E1 synthetic peptides could be involved in preventing the entry of HIV-1 by binding to the HIV-1 FP. Therefore, the continued study into the interaction between GBV-C peptides and HIV-1 FP could lead to the development of new therapeutic agents for the treatment of AIDS

Anticitrullinated peptide antibodies (ACPA) in the serum of heavy smokers without arthritis - a differential role of associated pulmonary disease?

2 páginas, 1 tabla.-- Póster presentado al 5º European Workshop on Immune-Mediated Inflammatory Diseases celebrado en Sitges (Barcelona) del 1 al 3 de Diciembre de 2010.An increased risk of RA has been described in smokers, but only in ACPA-positive RA patients. The frequency of ACPA in serum of heavy smokers is not known.Peer reviewe

Chilling accumulation in fruit trees in Spain under climate change

Growing trees are quite vulnerable to cold temperatures. To minimise the effect of these cold temperatures, they stop their growth over the coldest months of the year, a state called dormancy. In particular, endodormancy requires accumulating chilling temperatures to finish this sort of dormancy. The accumulation of cool temperatures according to specific rules is called chilling accumulation, and each tree species and variety has specific chilling requirements for correct plant development. Under global warming, it is expected that the fulfilment of the chilling requirements to break dormancy in fruit trees could be compromised. In this study, the impact of climate change on the chilling accumulation over peninsular Spain and the Balearic Islands was assessed. For this purpose, bias-adjusted results of 10 regional climate models (RCMs) under Representative Concentration Pathways (RCPs) 4.5 and 8.5 were used as inputs of four different models for calculating chilling accumulation, and the results for each model were individually compared for the 2021–2050 and 2071–2100 future periods under both RCPs. These results project a generalised reduction in chilling accumulation regardless of the RCP, future period or chilling calculation model used, with higher reductions for the 2071–2100 period and the RCP8.5 scenario. The projected winter chill decrease may threaten the viability of some tree crops and varieties in some areas where the crop is currently grown, but also shows scope for varieties with lower chilling requirements. The results are relevant for planning future tree plantations under climate change, supporting adaptation of spatial distribution of tree crops and varieties in Spain.</p

Novel Human Rotavirus Genotype G5P[7] from Child with Diarrhea, Cameroon

We report characterization of a genotype G5P[7] human rotavirus (HRV) from a child in Cameroon who had diarrhea. Sequencing of all 11 gene segments showed similarities to >5 genes each from porcine and human rotaviruses. This G5P[7] strain exemplifies the importance of heterologous animal rotaviruses in generating HRV genetic diversity through reassortment