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Sea ice–ocean feedbacks in the Antarctic shelf seas
Observed changes in Antarctic sea ice are poorly understood, in part due to the complexity of its interactions with the atmosphere and ocean. A highly simplified, coupled sea ice–ocean mixed layer model has been developed to investigate the importance of sea ice–ocean feedbacks on the evolution of sea ice and the ocean mixed layer in two contrasting regions of the Antarctic continental shelf ocean: the Amundsen Sea, which has warm shelf waters, and the Weddell Sea, which has cold and saline shelf waters. Modeling studies where we deny the feedback response to surface air temperature perturbations show the importance of feedbacks on the mixed layer and ice cover in the Weddell Sea to be smaller than the sensitivity to surface atmospheric conditions. In the Amundsen Sea the effect of surface air temperature perturbations on the sea ice are opposed by changes in the entrainment of warm deep waters into the mixed layer. The net impact depends on the relative balance between changes in sea ice growth driven by surface perturbations and basal-driven melting. The changes in the entrainment of warm water in the Amundsen Sea were found to have a much larger impact on the ice volume than perturbations in the surface energy budget. This creates a net negative ice albedo feedback in the Amundsen Sea, reversing the sign of this typically positive feedback mechanism
Geobase Information System Impacts on Space Image Formats
As Geobase Information Systems increase in number, size and complexity, the format compatability of satellite remote sensing data becomes increasingly more important. Because of the vast and continually increasing quantity of data available from remote sensing systems the utility of these data is increasingly dependent on the degree to which their formats facilitate, or hinder, their incorporation into Geobase Information Systems. To merge satellite data into a geobase system requires that they both have a compatible geographic referencing system. Greater acceptance of satellite data by the user community will be facilitated if the data are in a form which most readily corresponds to existing geobase data structures. The conference addressed a number of specific topics and made recommendations
Remote sensing applications to hydrologic modeling in the southern Sierra Nevada and portions of the San Joaquin Valley, volume 1
The author has identified the following significant results. Characteristics of LANDSAT MSS imagery present problems in using satellite radiation measurements to estimate the shortwave albedo of an alpine snow cover. Every 15 minute USGS quadrangle contains over 100,000 pixels which poses a computation problem if each pixel is to be evaluated individually. The sampling interval may be sufficiently great to mask some effects of terrain and vegetation on reflectance. Three frames of LANDSAT imagery are needed for complete coverage of the study area, yet less than one third of the area coverage from each frame covers an area of interest. Because of distortions inherent in the imagery, information regarding spacecraft altitude, attitude, and position must be statistically derived with respect to ground control points in the image whose geodetic locations are known. An inspection of shade points indicates that up to one third of the most heavily snow covered areas may saturate in bands 4 through 6. LANDSAT's 9 day repeat cycle is not optimum for snow cover reflectance modeling because the most pronounced changes in albedo occur most nearly following a new snowfall. Such a snowfall, occurring between overpasses, is inadequately represented by extrapolation from the previous overpasses
The effectiveness and cost-effectiveness of parent training/education programmes for the treatment of conduct disorder, including oppositional defiant disorder, in children
Objectives: To assess the clinical and cost-effectiveness of parent training programmes for the treatment of children with conduct disorder ( CD) up to the age of 18 years.
Data sources: Electronic databases.
Review methods: For the effectiveness review, relevant studies were identified and evaluated. A quantitative synthesis of behavioural outcomes across trials was also undertaken using two approaches: vote counting and meta-analysis. The economic analysis consisted of reviewing previous economic/cost evaluations of parent training/education programmes and the economic information within sponsor's submissions; carrying out a detailed exploration of costs of parent training/education programmes; and a de novo modelling assessment of the cost-effectiveness of parent training/education programmes. The potential budget impact to the health service of implementing such programmes was also considered.
Results: Many of the 37 randomised controlled trials that met the review inclusion and exclusion criteria were assessed as being of poor methodological quality. Studies were clinically heterogeneous in terms of the population, type of parent training/education programme and content, setting, delivery, length and child behaviour outcomes used. Both vote counting and meta-analysis revealed a consistent trend across all studies towards short-term effectiveness ( up to 4 months) of parent training/education programmes ( compared with control) as measured by a change in child behaviour. Pooled estimates showed a statistically significant improvement on the Eyberg Child Behaviour Inventory frequency and intensity scales, the Dyadic Parent - Child Interaction Coding System and the Child Behaviour Checklist. No studies reported a statistically significant result favouring control over parent training/education programmes. There were few statistically significant differences between different parent training/education programmes, although there was a trend towards more intensive interventions ( e. g. longer contact hours, additional child involvement) being more effective. The cost of treating CD is high, with costs incurred by many agencies. A recent study suggested that by age 28, costs for individuals with CD were around 10 times higher than for those with no problems, with a mean cost of 70,019 pound. Criminality incurs the greatest cost, followed by educational provision, foster and residential care and state benefits. Only a small proportion of these costs fall on health services. Using a 'bottom-up' costing approach, the costs per family of providing parent training/education programmes range from 629 pound to 3839 pound depending on the type and style of delivery. Using the conservative assumption that there are no cost savings from treatment, a total lifetime quality of life gain of 0.1 would give a cost per quality-adjusted life-year of between 38,393 pound and 6288 pound depending on the type of programme delivery and setting.
Conclusions: Parent training/education programmes appear to be an effective and potentially cost-effective therapy for children with CD. However, the relative effectiveness and cost-effectiveness of different models ( such as therapy intensity and setting) require further investigation. Further research is required on the impact of parent training/education programmes on the quality of life of children with CD and their parents/carers, as well as on longer term child outcomes
SPITZER SAGE Observations of Large Magellanic Cloud Planetary Nebulae
We present IRAC and MIPS images and photometry of a sample of previously
known planetary nebulae (PNe) from the SAGE survey of the Large Magellanic
Cloud (LMC) performed with the Spitzer Space Telescope. Of the 233 known PNe in
the survey field, 185 objects were detected in at least two of the IRAC bands,
and 161 detected in the MIPS 24 micron images. Color-color and color-magnitude
diagrams are presented using several combinations of IRAC, MIPS, and 2MASS
magnitudes. The location of an individual PN in the color-color diagrams is
seen to depend on the relative contributions of the spectral components which
include molecular hydrogen, polycyclic aromatic hydrocarbons (PAHs), infrared
forbidden line emission from the ionized gas, warm dust continuum, and emission
directly from the central star. The sample of LMC PNe is compared to a number
of Galactic PNe and found to not significantly differ in their position in
color-color space. We also explore the potential value of IR PNe luminosity
functions (LFs) in the LMC. IRAC LFs appear to follow the same functional form
as the well-established [O III] LFs although there are several PNe with
observed IR magnitudes brighter than the cut-offs in these LFs.Comment: 18 pages, 10 figures, 3 tables, to be published in the Astronomical
Journal. Additional online data available at
http://www.cfa.harvard.edu/irac/publications
Estimating the binary fraction of planetary nebulae central stars
During the past 20 years, the idea that non-spherical planetary nebulae (PN)
may need a binary or planetary interaction to be shaped was discussed by
various authors. It is now generally agreed that the varied morphologies of PN
cannot be fully explained solely by single star evolution. Observationally,
more binary central stars of planetary nebulae (CSPN) have been discovered,
opening new possibilities to understand the connections between binarity and
morphology. So far, \simeq 45 binary CSPN have been detected, most being close
systems detected via flux variability. To determine the PN binary fraction, one
needs a method to detect wider binaries. We present here recent results
obtained with the various techniques described, concentrating on binary
infrared excess observations aimed at detecting binaries of any separation.Comment: 2 pages, IAU 283: An Eye To The Future proceeding
The Atlantic Ocean surface microlayer from 50°N to 50°S is ubiquitously enriched in surfactants at wind speeds up to 13 m s−1
We report the first measurements of surfactant activity (SA) in the sea surface microlayer (SML) and in subsurface waters (SSW) at the ocean basin scale, for two Atlantic Meridional Transect from cruises 50°N to 50°S during 2014 and 2015. Northern Hemisphere (NH) SA was significantly higher than Southern Hemisphere (SH) SA in the SML and in the SSW. SA enrichment factors (EF = SASML/SASSW) were also higher in the NH, for wind speeds up to ~13 m s−1, questioning a prior assertion that Atlantic Ocean wind speeds >12 m s−1 poleward of 30°N and 30°S would preclude high EFs and showing the SML to be self-sustaining with respect to SA. Our results imply that surfactants exert a control on air-sea CO2 exchange across the whole North Atlantic CO2 sink region and that the contribution made by high wind, high latitude oceans to air-sea gas exchange globally should be reexamined
Spitzer IRAC observations of newly-discovered planetary nebulae from the Macquarie-AAO-Strasbourg H-alpha Planetary Nebula Project
We compare H-alpha, radio continuum, and Spitzer Space Telescope (SST) images
of 58 planetary nebulae (PNe) recently discovered by the Macquarie-AAO-Strasbo-
urg H-alpha PN Project (MASH) of the SuperCOSMOS H-alpha Survey. Using InfraRed
Array Camera (IRAC) data we define the IR colors of PNe and demonstrate good
isolation between these colors and those of many other types of astronomical
object. The only substantive contamination of PNe in the color-color plane we
illustrate is due to YSOs. However, this ambiguity is readily resolved by the
unique optical characteristics of PNe and their environs. We also examine the
relationships between optical and MIR morphologies from 3.6 to 8.0um and
explore the ratio of mid-infrared (MIR) to radio nebular fluxes, which is a
valuable discriminant between thermal and nonthermal emission. MASH emphasizes
late evolutionary stages of PNe compared with previous catalogs, enabling study
of the changes in MIR and radio flux that attend the aging process. Spatially
integrated MIR energy distributions were constructed for all MASH PNe observed
by the GLIMPSE Legacy Project, using the H-alpha morphologies to establish the
dimensions for the calculations of the Midcourse Space Experiment (MSX), IRAC,
and radio continuum (from the Molonglo Observatory Synthesis Telescope and the
Very Large Array) flux densities. The ratio of IRAC 8.0-um to MSX 8.3-um flux
densities provides a measure of the absolute diffuse calibration of IRAC at 8.0
um. We independently confirm the aperture correction factor to be applied to
IRAC at 8.0um to align it with the diffuse calibration of MSX. The result
agrees with the recommendations of the Spitzer Science Center and with results
from a parallel study of HII regions. These PNe probe the diffuse calibration
of IRAC on a spatial scale of 9-77 arcsec.Comment: 48 pages, LaTeX (aastex), incl. 18 PostScript (eps) figures and 3
tables. Accepted by Astrophysical Journa
The Chandra X-ray Survey of Planetary Nebulae (ChanPlaNS): Probing Binarity, Magnetic Fields, and Wind Collisions
We present an overview of the initial results from the Chandra Planetary
Nebula Survey (ChanPlaNS), the first systematic (volume-limited) Chandra X-ray
Observatory survey of planetary nebulae (PNe) in the solar neighborhood. The
first phase of ChanPlaNS targeted 21 mostly high-excitation PNe within ~1.5 kpc
of Earth, yielding 4 detections of diffuse X-ray emission and 9 detections of
X-ray-luminous point sources at the central stars (CSPNe) of these objects.
Combining these results with those obtained from Chandra archival data for all
(14) other PNe within ~1.5 kpc that have been observed to date, we find an
overall X-ray detection rate of ~70%. Roughly 50% of the PNe observed by
Chandra harbor X-ray-luminous CSPNe, while soft, diffuse X-ray emission tracing
shocks formed by energetic wind collisions is detected in ~30%; five objects
display both diffuse and point-like emission components. The presence of X-ray
sources appears correlated with PN density structure, in that molecule-poor,
elliptical nebulae are more likely to display X-ray emission (either point-like
or diffuse) than molecule-rich, bipolar or Ring-like nebulae. All but one of
the X-ray point sources detected at CSPNe display X-ray spectra that are harder
than expected from hot (~100 kK) central star photospheres, possibly indicating
a high frequency of binary companions to CSPNe. Other potential explanations
include self-shocking winds or PN mass fallback. Most PNe detected as diffuse
X-ray sources are elliptical nebulae that display a nested shell/halo structure
and bright ansae; the diffuse X-ray emission regions are confined within inner,
sharp-rimmed shells. All sample PNe that display diffuse X-ray emission have
inner shell dynamical ages <~5x10^3 yr, placing firm constraints on the
timescale for strong shocks due to wind interactions in PNe.Comment: 41 pages, 6 figures; submitted to the Astronomical Journa
The Impact of Body Mass Index Upon the Efficacy of Adalimumab in Hidradenitis Suppurativa
Elevated BMI in Hidradenitis Suppurativa is associated with decreased response to Adalimumab therapy. BMI is proposed to segregate distinct disease subtypes. It remains unresolved whether a threshold BMI exists above which increased dosages may provide clinical benefit. Individual patient data from 578 PIONEER Phase 3 participants were analyzed. Descriptive, multivariable regression analysis and receiver operating characteristic (ROC) curves were calculated to assess the relationship between BMI and clinical outcome measures using R v3.5.3. Participants in the overweight and obese BMI category had reduced odds (58 and 67%, respectively) of achieving HiSCR [OR = 0.42 (95%CI −0.19, 0.91) p = 0.03], [OR = 0.33 (95%CI 0.16, 0.67) p = 0.002] compared to participants with BMI < 25. Reduction in AN count and IHS4 score was not significantly associated. ROC analysis did not reveal any cut off value predictive of treatment outcome. No correlation between BMI and baseline disease activity or covariate interactions were identified. These findings suggest BMI is a significant covariate in the setting of lower baseline disease activity, supporting the concept of disease heterogeneity and differential therapeutic response to Adalimumab
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