1,055 research outputs found
Solving Scheduling Problems with Genetic Algorithms using a Priority Encoding Scheme
Scheduling problems are very hard computational tasks with several applications in multitude of domains. In this work we solve a practical problem motivated by a real industry situation, in which we apply a genetic algorithm for finding an acceptable solution in a very short time interval. The main novelty introduced in this work is the use of a priority based chromosome codification that determines the precedence of a task with respect to other ones, permitting to introduce in a very simple way all problem constraints, including setup costs and workforce availability. Results show the suitability of the approach, obtaining real time solutions for tasks with up to 50 products.Universidad de Málaga.Campus de Excelencia Internacional AndalucĂa Tech
Ethnic Concerns and Latino Party Identification [post-print]
The accelerated growth of the Latino population in the United States has made Latinos a coveted addition to each major political party\u27s base. In this paper we examine the influence of ethnic concerns on the party identification of Latinos in the U.S. In contrast to previous studies, we account for Latinos’ perceptions of the political parties’ concern for their ethnic interests, allowing such interests to be self-defined. In a multinomial logit analysis of pooled data from three surveys of Latinos taken in 1999, 2004, and 2006, we find such perceptions do affect Latino partisanship, along with variables such as nativity and country of origin or ancestry. We also find a tendency toward independence among Latinos. Finally, we find movement toward the Democratic Party in 2004, once ethnic concerns are taken into account. One implication of the findings is that the party that can best persuade Latinos of their concern for their interests is the party most likely to gain their loyalties; indeed, the parties must earn those loyalties
Towards the understanding of the activity of G9a inhibitors: an activity landscape and molecular modeling approach
In this work, we analyze the structure–activity relationships (SAR) of epigenetic inhibitors (lysine mimetics) against lysine
methyltransferase (G9a or EHMT2) using a combined activity landscape, molecular docking and molecular dynamics
approach. The study was based on a set of 251 G9a inhibitors with reported experimental activity. The activity landscape
analysis rapidly led to the identifcation of activity clifs, scafolds hops and other active an inactive molecules with distinct
SAR. Structure-based analysis of activity clifs, scafold hops and other selected active and inactive G9a inhibitors by means
of docking followed by molecular dynamics simulations led to the identifcation of interactions with key residues involved
in activity against G9a, for instance with ASP 1083, LEU 1086, ASP 1088, TYR 1154 and PHE 1158. The outcome of this
work is expected to further advance the development of G9a inhibitors
Three dimensional extended i m aging in the prenatal diagnosisof Galen vein aneurism: a case report
Galen vein aneurism (GVA) corresponds to a vascular dilation of the
sinus venous in central nervous system (CNS). GVA is a rare category
of congenital anomalies with a high mortality in neonatal and
pediatric life. Regular diagnostic methods consist of 2D ultrasound
and transvaginal neurosonogram when possible. Arteriovenous
malformation are a heterogeneous group of dilated deep vein
anomalies of Galen system with abnormal communications of the
mid line. It is presented in 1 : 250000 deliveries. Main complications include heart failure in the neonatal period, hydrocephalus, brain
calcifications, encephalomalacia, cerebral atrophy, bleeding and
neurological progressive compromise. We describe a case of GVA
diagnosed at 38 wo. Fetal evaluation was performed using Accuvix
V10 ultrasonographic equipment (Medison. Seoul-Korea). Cerebral
images were obtained using Virtual Organ Computer-aided AnaLysis
(VOCALTM , 3DXI, Medison Sonoview Pro, Seoul, Korea) with 30
degrees swept. The obtained volumes were analyzed in the postprocessor software 3DXI viewer and clinically correlated
Scale Invariance in a Non-Abelian Chern-Simons-Matter Model
The general method of reduction in the number of coupling parameters is
applied in a Chern-Simons-matter model with several independent couplings. We
claim that considering the asymptotic region, and expressing all dimensionless
coupling parameters as functions of the Chern-Simons coupling, it is possible
to show that all -functions vanish to any order of perturbative series.
Therefore, the model is asymptotically scale invariant.Comment: 8 pages, Latex2e, title changed, section 2 withdrawn and one
reference added. To appear in Phys.Lett.
X-boson cumulant approach to the periodic Anderson model
The Periodic Anderson Model (PAM) can be studied in the infinite U limit by
employing the Hubbard X operators to project out the unwanted states. We have
already studied this problem employing the cumulant expansion with the
hybridization as perturbation, but the probability conservation of the local
states (completeness) is not usually satisfied when partial expansions like the
Chain Approximation (CHA) are employed. Here we treat the problem by a
technique inspired in the mean field approximation of Coleman's slave-bosons
method, and we obtain a description that avoids the unwanted phase transition
that appears in the mean-field slave-boson method both when the chemical
potential is greater than the localized level Ef at low temperatures (T) and
for all parameters at intermediate T.Comment: Submited to Physical Review B 14 pages, 17 eps figures inserted in
the tex
A particle system with explosions: law of large numbers for the density of particles and the blow-up time
Consider a system of independent random walks in the discrete torus with
creation-annihilation of particles and possible explosion of the total number
of particles in finite time. Rescaling space and rates for
diffusion/creation/annihilation of particles, we obtain a stong law of large
numbers for the density of particles in the supremum norm. The limiting object
is a classical solution to the semilinear heat equation u_t =u_{xx} + f(u). If
f(u)=u^p, 1<p \le 3, we also obtain a law of large numbers for the explosion
time
The additive effect of adherence to multiple healthy lifestyles on subclinical atherosclerosis: Insights from the AWHS
Background: Public health strategies targeting multiple healthy behaviors, rather than individual factors, have been proposed as more efficient strategies to promote cardiovascular health. However, the additive effect of multiple targets on primary prevention has not been fully characterized. Objective: To examine how adherence to multiple healthy behaviors is associated with the presence of subclinical atherosclerosis, a measure of early cardiovascular disease.
Methods: Analysis of a baseline data from 1798 middle-aged men from the Aragon Workers Health Study conducted between 2009 and 2010. Healthy behaviors were defined according to American Heart Association recommendations, aligned with Spanish Nutritional recommendations and included moderate alcohol consumption, smoking abstinence, no abdominal adiposity, decreased sedentarism, and adherence to Alternate Mediterranean Dietary Index. Presence of coronary artery calcium and plaques in femoral and carotid was quantified by a 16-slice computed tomography scanner and 2D ultrasound.
Results: Moderate alcohol consumption, as well as adherence to Mediterranean diet is independently associated with a 6% lower risk of having subclinical atherosclerosis. Smoking abstinence is associated with a 11% lower risk of subclinical atherosclerosis. Those who follow 3 lifestyle behaviors (Mediterranean diet, nonsmoking, and moderate alcohol intake) have 18% lower odds of presenting subclinical atherosclerosis compared with those who do not follow these protective lifestyle habits.
Conclusion: Adoption of multiple healthy lifestyle behaviors early in life could be a key strategy to tackle the onset of atherosclerosis and reduce cardiovascular disease burden
Elastic Scattering of Pions From the Three-nucleon System
We examine the scattering of charged pions from the trinucleon system at a
pion energy of 180 MeV. The motivation for this study is the structure seen in
the experimental angular distribution of back-angle scattering for pi+ 3He and
pi- 3H but for neither pi- 3He nor pi+ 3H. We consider the addition of a double
spin flip term to an optical model treatment and find that, though the
contribution of this term is non-negligible at large angles for pi+ 3He and pi-
3H, it does not reproduce the structure seen in the experiment.Comment: 15 pages + 5 figure
Informe de la campaña de investigaciĂłn pesquera CentroamĂ©rica-PacĂfico 2010, 10 de noviembre al 16 de diciembre de 2010, B/O Miguel Oliver
Equipo de PesquerĂas Lejanas. Centro Oceanográfico de Vigo del IEO
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