MARKETING ESTRATÉGICO PARA SUBCULTURAS: UM ESTUDO SOBRE HOSPITALIDADE E GASTRONOMIA VEGETARIANA EM RESTAURANTES DA CIDADE DE SÃO PAULO

This study deals with hospitality from a perspective of receiving and welcoming in the commercial context of restaurants, whose existence in relation to consumers belonging to the vegetarian subculture is outlined based on the understanding of their motives and consumer habits. With the support of an exploratory survey, this work seeks, initially, to discover some consumer habits and attitudes of vegetarians who frequent restaurants in the city of São Paulo. With the data from this survey, a semi-structured observation script was formed. Seven restaurants were studied, in the same city, recommended by the subculture and considered appropriate for vegetarians. It was observed that even when serving a subculture, this does not always occur as a strategic decision, result of a market focus, a fact which could lead to its lack of success. The study of restaurants reveals nuances in vegetarian gastronomy that are unknown by the majority of catering establishments. Key words: Vegetarian gastronomy; Hospitality; Restaurants.Este estudio versa sobre la hospitalidad, bajo el enfoque del recibir y del acoger, en el contexto comercial de restaurantes, cuya existencia con relación a los consumidores pertenecientes a la subcultura vegetariana se delinea con la comprensión de sus motivaciones y de sus hábitos de consumo. Con el apoyo de una pesquisa exploratoria, se buscó, en una primera etapa, conocer algunos hábitos y actitudes de consumo de vegetarianos que frecuentan restaurantes en la ciudad de São Paulo. Con los datos de esta investigación, se formateó un plan semi-estructurado de observación. Se estudiaron siete restaurantes de la misma ciudad, indicados por la subcultura, considerados aptos a atender vegetarianos. Se percibe que, aún cuando hay atención a la subcultura, eso no siempre ocurre como una decisión estratégica, resultado del foco en el mercado, hecho que puede incurrir en su fracaso. El estudio de los restaurantes permitió revelar nuances de la gastronomía vegetariana, aún desconocida por gran parte de las empresas de servicios de alimentación. Palabras-clave: Gastronomía vegetariana; Hospitalidad; Restaurantes.Este estudo versa sobre a hospitalidade, sob o enfoque do receber e do acolher, no contexto comercial de restaurantes, cuja existência em relação aos consumidores pertencentes a subcultura vegetariana se delineia com a compreensão das suas motivações e dos seus hábitos de consumo. Com o apoio de uma pesquisa exploratória, buscou-se, em uma primeira etapa, conhecer alguns hábitos e atitudes de consumo de vegetarianos que freqüentam restaurantes na cidade de São Paulo. Com os dados desta pesquisa, formatou-se um roteiro semi-estruturado de observação. Foram estudados sete restaurantes da mesma cidade, indicados pela subcultura, considerados aptos a atender vegetarianos. Percebe-se que, mesmo quando há atendimento à subcultura, isso nem sempre ocorre como uma decisão estratégica, resultado do foco no mercado, fato que pode incorrer no seu insucesso. O estudo dos restaurantes permitiu revelar nuances da gastronomia vegetariana, ainda desconhecida por grande parte das empresas de serviços de alimentação. Palavras-chave: Gastronomia vegetariana; Hospitalidade; Restaurantes

Tratamento da leucemia linfóide aguda em crianças: uma revisão narrativa

A Leucemia Linfoide Aguda (LLA) é uma neoplasia caracterizada por uma proliferação de linfoides primitivos. É mais comum na infância com um maior predomínio antes dos 5 anos de idade e representa o décimo câncer mais comum no Brasil. O objetivo desse trabalho é o entendimento das manifestações da doença e seus tratamentos, além de mostrar uma nova terapia que tem uma significativa promessa para o futuro do tratamento da LLA. São discutidos ao longo deste trabalho os sinais clínicos e diagnóstico da leucemia. E ainda, descrito os métodos diagnósticos e tratamentos que podem ser realizados, com suas principais indicações e efeitos adversos. Esta pesquisa surge a partir de uma revisão bibliográfica, baseando em publicações cientificas dos últimos 12 anos, realizada através da busca bibliográfica nos bancos de dados PubMed, Scielo, Google Acadêmico, Biblioteca Virtual em Saúde (BVS) e Portal Capes. Conclui-se que a LLA é uma neoplasia com evolução rápida e que necessita de uma abordagem multidisciplinar com uma assistência especializada em decorrência dos efeitos colaterais dos tratamentos. A quimioterapia e o transplante de células tronco mostram resultados com maiores taxas de recidiva. No entanto, a imunoterapia CAR-T cell tem mostrado resultados eficientes e promissores causando uma perspectiva importante na sobrevida da LLA

Dietary patterns associated to clinical aspects in Crohn's disease patients

Diet is an important factor in both the pathogenesis and in the clinical course of Crohn’s disease (CD). However, data on dietary patterns of CD patients are rather limited in the literature. This cross-sectional study included 60 patients with CD, aged 18–60 years. Dietary intake was assessed using a validated food frequency questionnaire to measure food consumption patterns by principal component analysis (PCA). Multiple regression analysis was performed to investigate the association between dietary patterns and clinical and demographic variables. Three dietary patterns were identified: “Traditional + FODMAP” was associated with symptoms, gender, previous surgeries, and duration of the disease. “Fitness style” was positively associated with physical activity and negatively associated with body mass index and smoking. “Snacks and processed foods” was positively associated with duration of the disease and negatively associated with age. According to the weekly food consumption analysis, patients with active disease consumed less coffee and tea. We found significant associations between the three dietary patterns and the variables, but not with the stage of the disease. Prospective studies are necessary to determine the effects of food consumption patterns on the clinical course of CD10COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPESnão te

Strategies to select yeast starter cultures for production of flavour compounds in cachaça fermentations.

In this work, we have used classical genetics techniques to find improved starter strains to produce cachac¸a with superior sensorial quality. Our strategy included the selection of yeast strains resistant to 5,50,500-trifluor-D,L-leucine (TLF) and cerulenin, since these strains produce higher levels of higher alcohols and esters than parental strains. However, no clear relationship was observed when levels of flavoring compounds were compared with the levels expression of the genes (BAT1, BAT2, ATF2, EEB1 genes) involved with the biosynthesis of flavoring compounds. Furthermore, we determined the stability of phenotypes considered as the best indicators of the quality of the cachac¸a for a parental strain and its segregants. By applying the principal component analysis, a cluster of segregants, showing a high number of characteristics similar to the parental strain, was recognized. One segregant, that was resistant to TLF and cerulenin, also showed growth stability after six consecutive replications on plates containing high concentrations of sugar and ethanol. ‘‘Cachac¸a’’ produced at laboratory scale using a parental strain and this segregant showed a higher level of flavoring compounds. Both strains predominated in an open fermentative process through seven cycles, as was shown by mitochondrial restriction fragment length polymorphisms analysis. Based on the physical chemical composition of the obtained products, the results demonstrate the usefulness of the developed strategies for the selection of yeast strains to be used as starters in ‘‘cachac¸a’’ production

Prevalence evolution of SARS-CoV-2 infection in the city of São Paulo, 2020–2021

OBJECTIVE To estimate the evolution of the prevalence of SARS-CoV-2 virus infection among residents aged 18 years or over in the municipality of São Paulo. METHODS This is a population-based household survey conducted every 15 days, between June and September 2020, and January and February 2021. In total, the study comprised 11 phases. The presence of antibodies against SARS-CoV-2 was identified in venous blood using a lateral flow test, Wondfo Biotech. In the last phase, the researchers combined it with an immunoenzymatic test, Euroimmun. The participants also answered a semi-structured questionnaire on sociodemographic and economic factors, and on social distancing measures. Prevalence estimates and the 95% confidence interval were estimated according to regions, Human Development Index, sex, age group, ethnicity, education, income, and variables associated with risk or prevention of infection. To compare the frequencies among the categories of each variable, the chi-square test with Rao-Scott correction was used, considering a significance level of 5%. RESULTS In total, 23,397 individuals were interviewed and had their samples collected. The estimated prevalence of antibodies against SARS-CoV-2 ranged from 9.7% (95%CI: 7.9–11.8%) to 25.0% (95%CI: 21.7–28.7). The prevalence of individuals with antibodies against the virus was higher among black and brown people, people with lower schooling and income, and among residents of regions with lower Human Development Index. The lowest prevalences were associated with recommended measures of disease protection. The proportion of asymptomatic infection was 45.1%. CONCLUSION The estimated prevalence of the infection was lower than the cumulative incidence variation, except for the last phase of the study. The differences in prevalence estimates observed among subpopulations showed social inequality as a risk of infection. The lower prevalence observed among those who could follow prevention measures reinforce the need to maintain social distancing measures as a way to prevent SARS-CoV-2 infection

NEOTROPICAL CARNIVORES: a data set on carnivore distribution in the Neotropics

Mammalian carnivores are considered a key group in maintaining ecological health and can indicate potential ecological integrity in landscapes where they occur. Carnivores also hold high conservation value and their habitat requirements can guide management and conservation plans. The order Carnivora has 84 species from 8 families in the Neotropical region: Canidae; Felidae; Mephitidae; Mustelidae; Otariidae; Phocidae; Procyonidae; and Ursidae. Herein, we include published and unpublished data on native terrestrial Neotropical carnivores (Canidae; Felidae; Mephitidae; Mustelidae; Procyonidae; and Ursidae). NEOTROPICAL CARNIVORES is a publicly available data set that includes 99,605 data entries from 35,511 unique georeferenced coordinates. Detection/non-detection and quantitative data were obtained from 1818 to 2018 by researchers, governmental agencies, non-governmental organizations, and private consultants. Data were collected using several methods including camera trapping, museum collections, roadkill, line transect, and opportunistic records. Literature (peer-reviewed and grey literature) from Portuguese, Spanish and English were incorporated in this compilation. Most of the data set consists of detection data entries (n = 79,343; 79.7%) but also includes non-detection data (n = 20,262; 20.3%). Of those, 43.3% also include count data (n = 43,151). The information available in NEOTROPICAL CARNIVORES will contribute to macroecological, ecological, and conservation questions in multiple spatio-temporal perspectives. As carnivores play key roles in trophic interactions, a better understanding of their distribution and habitat requirements are essential to establish conservation management plans and safeguard the future ecological health of Neotropical ecosystems. Our data paper, combined with other large-scale data sets, has great potential to clarify species distribution and related ecological processes within the Neotropics. There are no copyright restrictions and no restriction for using data from this data paper, as long as the data paper is cited as the source of the information used. We also request that users inform us of how they intend to use the data