CLIL Implementation applied to Mathematics for Engineering

CLIL methodology aims to facilitate the learning of contents in a second language. Authors have tested an experience of implementation in English of these methods in subjects of Mathematics for Engineering at the University of Malaga.CLIL methodology aims to facilitate the learning of contents in a second language. Authors have tested an experience of implementation in English of these methods in subjects of Mathematics for Engineering at the University of Malaga. - Objectives: To create groups which will be taught in English. To try to integrate concepts and maths terminology in the target language, in this case English, maintaining the lessons in Spanish. To improve the integration of foreign students and our student’s knowledge in the target language in order to gain mobility to other universities where English is offered. To elaborate teaching materials and assessment tests in English. - Method: Experience has been developed for two academic years in Engineering degrees at Malaga University in the frame of the Educational Innovative Project PIE17-181. Many students hold an adequate level of English, but some others do not know it enough to follow full teaching in English without difficulties. By keeping lessons and assessments in Spanish, we integrated, in a gradual way, materials such as notes, summaries, exercises and powerpoint documents , all written in English. The use of ICTs has been important for the development of this implementation. - Results: This methodology improves the student's English, mainly in the field of scientific/technical terminology, without loss of content in mathematics. - Conclusions: Among others, we believe that the results are positive and we will continue with this experience.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Control of Immunoregulatory Molecules by miRNAs in T Cell Activation

MiRNA targeting of key immunoregulatory molecules fine-tunes the immune response. This mechanism boosts or dampens immune functions to preserve homeostasis while supporting the full development of effector functions. MiRNA expression changes during T cell activation, highlighting that their function is constrained by a specific spatiotemporal frame related to the signals that induce T cell-based effector functions. Here, we update the state of the art regarding the miRNAs that are differentially expressed during T cell stimulation. We also revisit the existing data on miRNA function in T cell activation, with a special focus on the modulation of the most relevant immunoregulatory molecules.We thank Dr M. Vicente-Manzanares for critical reading of the manuscript and for assistance with English editing. This study was supported by the following grants from the Spanish Ministry of Economy and Competitiveness, (grant SAF2017-82886-R to FSM), CIBER CARDIOVASCULAR and PIE 13.0004-BIOIMID from the Instituto de Salud Carlos III (Fondo de Investigacion Sanitaria del Instituto de Salud Carlos III with co-funding from the Fondo Europeo de Desarrollo Regional; FEDER), Programa de Actividades en Biomedicina de la Comunidad de Madrid-B2017/BMD-3671-INFLAMUNE to FS-M, and ERC-2011-AdG294340-GENTRIS to FS-M. The Centro Nacional de Investigaciones Cardiovasculares (CNIC) is supported by the Spanish Ministry of Economy and Competitiveness (MINECO) and the Pro-CNIC Foundation and is a Severo Ochoa Center of Excellence (MINECOaward SEV-2015-0505). AR-G is supported by the FPU program (Spanish Ministry of Education). LF-M is funded by the CIBER CARDIOVASCULAR.S

Innovative Tourism Clusters: Myth or Reality? Empirical Evidence from Benidorm

Paper submitted to TCVT3 Bozen/Bolzano, 10-12 April 2014, International workshop on Tourists as Consumers, Visitors, TravellersThis paper analyses the applicability of the cluster concept to tourist destinations, taking Benidorm as the reference for study: a destination on the Mediterranean coast of Spain which has attained a high degree of competitive success with the sun and sand product in which it has specialized. The main result obtained is that Benidorm's success is not derived from or favoured by the existence of a cluster in the destination, since important elements are present that prevent affirmation of its existence. This paper is the preliminary result of a research project that has been carried out within the framework of the project "Methodology, criteria and impementation of the cluster theory in consolidated tourism areas: innovation, competitiveness and territorial synergies" under the Spanish National R&D&I Plan 2008-2011 supported by the Ministry of Science and Innovation.This research has been carried out within the framework of the project “Methodology, criteria and implementation of the cluster theory in consolidated tourism areas: innovation, competitiveness and territorial synergies” under the Spanish National R&D&I Plan 2008-2011 supported by the Ministry of Science and Innovation

El cuestionario como medio de evaluación en la implementación de nuevos procesos de enseñanza/aprendizaje en la Electrónica de Potencia

Las Nuevas Tecnologías de la Información y la Comunicación (NTIC) invaden los medios educacionales, comunicacionales y empresariales. Y eso hace que, al mundo que conocemos tradicionalmente ("real"), se sumen los entornos "virtuales" y de comunicaciones. Aplicadas al entorno educativo, las NTIC favorecen estilos docentes más flexibles y personalizados, fomentan la participación y el trabajo en equipo, estimulan el interés y motivación, facilitan el aprendizaje autónomo y mejoran el rendimiento académico de los estudiantes, produciéndose diversos cambios y modificaciones en los procesos de enseñanza/aprendizaje, que son analizados y estudiados en este trabajo.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

RThybrid: A standardized and open-source real-time software model library for experimental neuroscience

Closed-loop technologies provide novel ways of online observation, control and bidirectional interaction with the nervous system, which help to study complex non-linear and partially observable neural dynamics. These protocols are often difficult to implement due to the temporal precision required when interacting with biological components, which in many cases can only be achieved using real-time technology. In this paper we introduce RTHybrid (www.github.com/GNB-UAM/RTHybrid), a free and open-source software that includes a neuron and synapse model library to build hybrid circuits with living neurons in a wide variety of experimental contexts. In an effort to encourage the standardization of real-time software technology in neuroscience research, we compared different open-source real-time operating system patches, RTAI, Xenomai 3 and Preempt-RT, according to their performance and usability. RTHybrid has been developed to run over Linux operating systems supporting both Xenomai 3 and Preempt-RT real-time patches, and thus allowing an easy implementation in any laboratory. We report a set of validation tests and latency benchmarks for the construction of hybrid circuits using this library. With this work we want to promote the dissemination of standardized, user-friendly and open-source software tools developed for open- and closed-loop experimental neuroscience.This work was supported by MINECO/FEDER DPI2015-65833-P, TIN2017-84452-R and ONRG grant N62909-14-1-N27

The Gut Microbiota and Its Implication in the Development of Atherosclerosis and Related Cardiovascular Diseases

Julio Plaza-Díaz is part of the “UGR Plan Propio de Investigación 2016” and the “Excellence actions: Unit of Excellence on Exercise and Health (UCEES), University of Granada”. We are grateful to Belen Vazquez-Gonzalez for assistance with the illustration service.The importance of gut microbiota in health and disease is being highlighted by numerous research groups worldwide. Atherosclerosis, the leading cause of heart disease and stroke, is responsible for about 50% of all cardiovascular deaths. Recently, gut dysbiosis has been identified as a remarkable factor to be considered in the pathogenesis of cardiovascular diseases (CVDs). In this review, we briefly discuss how external factors such as dietary and physical activity habits influence host-microbiota and atherogenesis, the potential mechanisms of the influence of gut microbiota in host blood pressure and the alterations in the prevalence of those bacterial genera affecting vascular tone and the development of hypertension. We will also be examining the microbiota as a therapeutic target in the prevention of CVDs and the beneficial mechanisms of probiotic administration related to cardiovascular risks. All these new insights might lead to novel analysis and CVD therapeutics based on the microbiota

Solitary colonic polypoid ganglioneuroma

This short report discusses a case of solitary colonic polypoid ganglioneuroma associated with melanosis coli in a woman with no systemic manifestations. To our knowledge this is the first ganglioneuroma reported in the literature in association with melanosis coli. The nature and significance of this event remains unclear, although this may be coincidental due to the laxative intake. Further investigation is necessary to clarify this point. The interest of this case lies moreover in the rarity of this entity and its endoscopic and histologic resemblance to sessile polyps frequent in the clinical practice