11 research outputs found
Transposição do enxerto vascularizado da fíbula pro fêmur diafisário sem microanastomoses
- Author
- Al-Qattan MM.
- Angrigiani C
- Baudet J
- Bertelli JA
- Bertelli JA
- Cariou JL.
- Cavadas PC
- Chang N
- Cheng HH
- Chow SP
- Clécio Seiji Yuhara
- Dan Carai Maia Viola
- De Boer HD
- dos Santos LF
- dos Santos LF.
- Fabiano Inácio de Souza
- Fernanda Bogdanovics Paganotti
- Francisco Perez Soro Neto
- Georgescu AlV
- Ger R.
- Ger R.
- Guilherme Pelosini Gaiarsa
- Hallock GG
- Harii K.
- Hsiang Wei Teng
- Ishida LH
- Koshima I
- Koshima I
- Koshima I
- Leonardo Franco Pinheiro Gaia
- Luciano Ruiz Torres
- Masquelet AC
- Masquelet AC
- Mathes SJ
- Mattar Junior R
- Mattar Junior R
- McCraw JB
- McCraw JB
- McCraw JB
- Molski M
- Morris A.
- Nassif TM
- Orticochea M.
- Rames Mattar Júnior
- Recalde Rocha JF
- Recalde Rocha JF
- Salibian AH
- Satoh K
- Taylor GI
- Teng HW
- Teng HW
- Teo TC
- Toh S
- Torres LR
- Wei FC
- Wood MB
- Wood MB
- Yoshimura M
- Zalavras CG
- Zumiotti AV
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- 01/01/2010
- Field of study
Sex difference and intra-operative tidal volume: Insights from the LAS VEGAS study
- Author
- Adeline Gerard
- Adem Bytyqi
- Aggeliki Pandazi
- Ahmed Abdel-Razek
- Ahmed Chishti
- Ahmed Mostafa El-Shaarawy
- Alar Sormus
- Alastair Rose
- Albert Prades
- Alberto Lisi
- Alberto Zangrillo
- Aleksandra Lazukic
- Alena Breidablik
- Alenka Spindler-Vesel
- Alessandro Bacuzzi
- Alexander Kulikov
- Alexander Lugovoy
- Alexandre Molin
- Alexandru Bogdan Prodan
- Alexey Gritsan
- Alexey Ovezov
- Ali Saltali
- Alice Werger
- Alida Moise
- Alistair Cain
- Alyson Andrew
- Amanda Datson
- Ambra Licia Di Parma
- Amir Rafi
- Amir Shafi-Kabir
- Ana de Abajo Larriba
- Ana Fernandez- Bustamante
- Ana Maria Petcu
- Ana Pekle-Golez
- Ana Ricardo
- Andre Gottschalk
- Andrea Bell
- Andrea Brunelli
- Andrea Cortegiani
- Andreas Gueldner
- Andreas Reske
- Andrew Donovan
- Andrey Babayants
- Andrey Lubnin
- Andriy Grynyuk
- Andriy Mazur
- Anette Bundy
- Angela Almagro
- Angela Monteirosa
- Angelo Gratarola
- Ann De Bruyne
- Anna Fouracres
- Anna Marija Pavicic
- Annamaria Campanile
- Anne Duvekot
- Annika Aun
- Antoine Petit
- Antonella Marrella
- Antonino Giarratano
- Antonio Martínez Simon
- Antonio Zilic
- Antonis Andreou
- Arieh Eden
- Ashok Das
- Ashok Raj
- Audrey Pospiech
- Aurika Karbonskiene
- Bahar Kuvaki
- Barbka Novak-Supe
- Bas in ‘t Veld
- Baturay Kansu Kazbek
- Bea Bastin
- Ben Creagh-Brown
- Ben Schwerdtfeger
- Ben Shelley
- Benedikt Pannen
- Benoit Plichon
- Bernhard Urbanek
- Binnekade Jan M
- Bjorn Heyse
- Branka Maldini
- Branka Mazul-Sunko
- Branka Strazisar
- Branwen Ellison
- Brigitte Leva
- Cait Goodall
- Carlo Alberto Volta
- Carlos Ferrando
- Carlos Puigbo
- Catalin-Traian Guran
- Caterina Valeria Pesce
- Ceren Sanlikarip
- Cesar Aldecoa Alvares-Santullano
- Charley Higham
- Charlotte Severijns
- Christa Boer
- Christian Nestler
- Christopher Uhlig
- Christos Nouris
- Chryssa Pourzitaki
- Claire West
- Clare Jackson
- Colin Barrett
- Concezione Tommasino
- Corrado Liperi
- Cristina Saiz Ruiz
- Dalip Muhardri
- Dan Corneci
- Dan Costea
- Dana Tomescu
- Daniel Ferreira
- Daniela Filipescu
- Daniela La Bella
- Daniele Sances
- Danielle Franklin
- Darija Azenic-Venzera
- Daryl Kor
- David Kahn
- David Portch
- David Rogerson
- Davide D'antini
- Debbie Fuller
- Deborah Clements
- Dejana Djonoviċ- Omanoviċ
- Demet Sulemanji
- Denny Tran Thiem
- Diana Westerheide
- Dimitri Dylst
- Dimitrios Valsamidis
- Dimitris Karapanos
- Diogo Martins
- Dmitri Bystritski
- Dubravka Ivic
- Dunja Mihajlovic
- Egle Kontrimaviciute
- Eiko Herodes
- Elaine Rogers
- Elena Sardo
- Elisa Brugnoni
- Elisabeth Andersson
- Elizabeth Homan
- Elizabeth Luzier
- Emily Calton
- Emmanuel Futier
- Emmanuel Marret
- Emre Camci
- Enrique Moret
- Erick Morais
- Erika Salciute
- Ernesto Pastor
- Eyup Aydogan
- Fatma Mine Karaman
- Fatma Nur Akgun
- Fatos Sada
- Federica Scavonetto
- Felicity Mackenzie
- Ferim Gunenc
- Fernande Lois
- Fevzi Toraman
- Filippo Bressan
- Foteini Zafeiropoulou
- Francesca Montalto
- Francesca Rapido
- Francesco Bona
- Francis Joseph Borg
- Francisco Hidalgo Martinez
- Frederic Rodenas
- Frode Fjellanger
- Gabija Tomkute
- Gabriela Droc
- Gabriele Sales
- Galina Gritsan
- Gama de Abreu Marcelo
- Gary Mills
- Gary Minto
- Gecaj-Gashi Agreta
- Georgia Tsaousi
- Georgios Antholopoulos
- Georgios Gkiokas
- Gerd Struber
- Gianluca Castellani
- Gianluca Spano
- Gianmarco Giacoletto
- Gilda Cinnella
- Giorgia Cerati
- Giovanni Landoni
- Gisela Perez
- Giulia Pellerano
- Giuseppe Musella
- Giuseppe Servillo
- Glória Tareco
- Goncalves Castro
- Gorjana Erceg
- Guy Rousseau
- Hana Harazim
- Hans Gombotz
- Hany Yassin
- Hedenstierna Goran
- Helen Roberts
- Helen Scholes
- Helfried Metzler
- Hemmes Sabrine N T
- Hermann Wrigge
- Hiesmayr Michael
- Hisham Hosny Abdelwahab
- Hol Liselotte
- Hollmann Markus W
- Hrvoje Vinkovic
- Ib Jammer
- Ines Arpino
- Inga Mladic-Batinica
- Ioana Cristina Grintescu
- Ioana Marina Grintescu
- Ioana Popescu Garotescu
- Iole Brunetti
- Iorel Gherghina
- Irene Wiersma
- Irina Grosu
- Irina Komissarova
- Iulia Cindea
- Ivan Kostadinov
- Ivan Mirkovic
- Ivana Oputric
- Ivana Volfova
- Jaber Samir
- Jadranka Pavicic Saric
- Jale Maral
- James Limb
- Jan Brujevic
- Jan Poelaert
- Jane Montgomery
- Janet Palmer
- Jannicke Mellin-Olsen
- Jasmina Markovic-Bozi
- Jasmina Pejakovic
- Jasminka Kopic
- Jasper De Jong
- Jaume Canet
- Jayne Foot
- Jaysimha Susarla
- Jens Hering
- Jens Krassler
- Jeroen van Melkebeek
- Jesus Rico
- Jill Deane
- Joana Amaral
- Johann Geib
- John Williams
- John Xuereb
- Jonathan Paddle
- Jose Antonio de Andrés Ibañez
- Jose Tatay Vivo
- Josep Fava
- Josip Zunic
- Julie Colley
- Juraj Sprung
- Jurgen Van Limmen
- Juri Karjagin
- Juri Oganjan
- Kaili Sarapuu
- Kamil Hudacek
- Karen Simeson
- Karginova Zalina
- Kassiani Theodoraki
- Katarina Bruncakova
- Katarina Liskova
- Katerina Jirmanova
- Katerina Vitkova
- Katharina Skirstad Hodt
- Kazimir Juricic
- Konstantinos Stroumpoulis
- Krishnan Kodaganallur
- Lars Gillberg
- Laura Pasin
- Laura Pistidda
- Leanne Welch
- Lenka Polakovicova
- Liliana Mirea
- Lisa Wayman
- Luc De Baerdemaeker
- Luca Brazzi
- Luca Montagnani
- Lucia Mirabella
- Lucia Stancombe
- Lucia Zamidei
- Lucian Horhota
- Lucy Brown
- Luigi Beretta
- Luigi Delunas
- Luigi Giancarlo
- Luiz Fernando
- Lynn Everett
- Madalina Dutu
- Magda Riciu
- Mahdy Abdelhady
- Maka Zuleika
- Manuel Granell
- Manuel Vico Avalos
- Mar Sendra
- Marc Solier
- Marcel Gama de Abreu
- Marco Baciarello
- Marco Venturino
- Marco Verri
- Marcos Vidal Melo
- Marcus J
- Marcus Schultz
- Margaret Szewczyk
- Mari Carmen Unzueta
- Maria de Lurdes
- Maria Jose Yepes Temino
- Maria Nadolski
- Maria Vargas
- Maria Zelinkova
- Marian Irinel Tudoroiu
- Mariana Correia
- Marie-Claire van Malderen
- Marina Juros-Zovko
- Marina Soro
- Mario Defez
- Marios-Konstantinos Tasoulis
- Mark Pulletz
- Markus Hollmann
- Marta Eugenia Sassone
- Martin Scharffenberg
- Martin Weiss
- Martina Kosinova
- Matea Bogdanovic Dvorscak
- Matthew Rucklidge
- Maud Beran
- Maudrian Burton
- Maureen Bezzina
- Maurizio Solca
- Maximilian Schaefer
- Merilin Mall
- Michael Hiesmayr
- Michael Lundberg
- Michal Drab
- Michela Generali
- Michele De Michele
- Mihai Popescu
- Mihaly Veres
- Mills Gary H
- Minca Voje
- Mine Yildiz
- Mirja Konrad
- Mirna Sehovic
- Miroljub Jovanov
- Mladen Carev
- Mohamed Magdy
- Mohamed Mahran
- Mona Momeni
- Monir Jawad
- Moses Chikungwa
- Mrutyunjaya Rambhatla
- Murat Yilmaz
- Mónica Rodriguez Nunez
- Natalia Anipchenko
- Natasa Dropulic
- Nathalie Roels
- Necmiye Hadimioglu
- Nenad Karanovic
- Nesil Coskunfirat
- Neval Boztug
- Nicholas Boyd
- Nijbroek Sunny G
- Nukhet Sivrikoz
- Nuzhet Mert Senturk
- Oguzhan Arun
- Oleg Korolkov
- Olga Smekalova
- Onur Selvi
- Otto Mohr
- Ozgur Senturk
- Pablo Monedero
- Panagiota Florou
- Paola Morelli
- Paolo Pelosi
- Paolo Severgnini
- Parizade Raymode
- Pasquale Raimondo
- Patrice Forget
- Paul Dennesen
- Paula Dzurnakova
- Pauline Mercer
- Pavel Prokoshev
- Peeter Kivik
- Pelosi Paolo
- Petar Miskovic
- Peter Carvalho
- Peter Kienbaum
- Peter Spieth
- Petr Stourac
- Philip Watt
- Philipp Simon
- Piet Wyffels
- Povilas Miliauskas
- Putensen Christian
- Rachel Walker
- Radek Filipsky
- Radovan Dudas
- Raquel Martinez
- Renatas Tikuisis
- Reuven Pizov
- Riccardo Ragazzi
- Rienk van Beek
- Roberto Dossi
- Roberto Zoppellari
- Rocio Perez
- Rosanna Sileo
- Ruby Molina
- Rupert Pearse
- Ruta Aukstakalniene
- Ruxandra Copotoiu
- Ruxandra Fota
- Sabrine Hemmes
- Salvatore Grasso
- Samir el Kafraw
- Samir Jaber
- Sanda-Maria Copotoiu
- Sandeep Kusre
- Sandeep Varma
- Sandrine Damster
- Santi Maurizio Raineri
- Sara Rodrigues
- Sara Sher
- Sarah Gibb
- Sarah Moreton
- Savino Spadaro
- Schmid Werner
- Schultz
- Selma Pernar
- Semih Kucukguclu
- Semra Kucukgoncu
- Septimiu Gheorghe Moldovan
- Sergei Fedorov
- Sergiy Vorotyntsev
- Serpa Neto Ary
- Serpil Ustalar Ozgen
- Severgnini Paolo
- Seyda Canli
- Shivarajan Algarsamy
- Silvius Negoita
- Simon Davies
- Simone Merzky
- Sipylaite Jurate
- Slavica Kvolik
- Sofia Appleton
- Sonja Skiljic
- Sopio Peradze
- Stanley Wutai
- Stefan de Hert
- Stefan Ivars
- Stefano Pezzatto
- Stefano Tredici
- Stephanie Jones
- Stephen Mowat
- Stijn van de Velde
- Suat Sanli
- Sudhakar Marri
- Suresh Venkatesh
- Susan Yates
- Susana Cadilha
- Suzana Parente
- Swart Pien
- Tanja Goranovic
- Tanja Treschan
- Tarek Metwally
- Tatiana Sidiropoulou
- Tatyana Kapkan
- Thais Creary
- Thea Koch
- Thomas Bluth
- Thomas Kiss
- Thomas Smith
- Thomas Wegscheider
- Toby Weingarten
- Tom Jacobs
- Tomas Kolacek
- Tomislav Radocaj
- Valentina Tarzia
- Valery Likhvantsev
- Vedran Frkovic
- Veerle van Mossevelde
- Vesna Novak-Jankovic
- Vicari Sottosanti
- Victoria Barsan
- Victoria Moral
- Vidal Melo Marcos F
- Villiam Sobona
- Vincenzo Russotto
- Vittoria Bartolini
- Werner Schmid
- Wolfgang Kroell
- Wrigge Hermann
- Yeo Tze
- Yigal Leykin
- Yousif Saeed
- Zeljka Gavranovic
- Zerrin Sungur
- Zivile Teberaite
- Zsolt Tolcser
- Zuleyha Kazak Bengisun
- Zuzana Kusnierikova
- Şule Ozbilgin
- Publication venue
- 'Ovid Technologies (Wolters Kluwer Health)'
- Publication date
- 01/01/2021
- Field of study
BACKGROUND: One key element of lung-protective ventilation is the use of a low tidal volume (VT). A sex difference in use of low tidal volume ventilation (LTVV) has been described in critically ill ICU patients.OBJECTIVES: The aim of this study was to determine whether a sex difference in use of LTVV also exists in operating room patients, and if present what factors drive this difference.DESIGN, PATIENTS AND SETTING: This is a posthoc analysis of LAS VEGAS, a 1-week worldwide observational study in adults requiring intra-operative ventilation during general anaesthesia for surgery in 146 hospitals in 29 countries.MAIN OUTCOME MEASURES: Women and men were compared with respect to use of LTVV, defined as VT of 8 ml kg-1 or less predicted bodyweight (PBW). A VT was deemed 'default' if the set VT was a round number. A mediation analysis assessed which factors may explain the sex difference in use of LTVV during intra-operative ventilation.RESULTS: This analysis includes 9864 patients, of whom 5425 (55%) were women. A default VT was often set, both in women and men; mode VT was 500 ml. Median [IQR] VT was higher in women than in men (8.6 [7.7 to 9.6] vs. 7.6 [6.8 to 8.4] ml kg-1 PBW, P < 0.001). Compared with men, women were twice as likely not to receive LTVV [68.8 vs. 36.0%; relative risk ratio 2.1 (95% CI 1.9 to 2.1), P < 0.001]. In the mediation analysis, patients' height and actual body weight (ABW) explained 81 and 18% of the sex difference in use of LTVV, respectively; it was not explained by the use of a default VT.CONCLUSION: In this worldwide cohort of patients receiving intra-operative ventilation during general anaesthesia for surgery, women received a higher VT than men during intra-operative ventilation. The risk for a female not to receive LTVV during surgery was double that of males. Height and ABW were the two mediators of the sex difference in use of LTVV.TRIAL REGISTRATION: The study was registered at Clinicaltrials.gov, NCT01601223
The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance
- Author
- Aanniz Tarek
- Abar Aden Elmi
- Abbad Anass
- Abdelfattah May
- Abdelhamid W.
- Abdella Saro
- Abdellah Faouzi
- Abdelmjid El Oualid
- Abdelmoula Fatma
- Abdelmoulah F.
- Abderrahmane Maaroufi
- Abderrazak Rfaki
- Abdillahi Idil Salah
- Abdissa Alemseged
- Abdo I.
- Abdoelraheem Mohamed Hassan
- Abe Haruka
- Abebe Markos
- Abechi Priscilla
- Abera Adugna
- Abi Rachid
- Abias Abe G.
- Abichu Getachew
- Abid N.
- Abid Nabil
- Abid Salma
- Abilio Nuro
- Abimbola Sharon
- Abo Shama Noura M
- Abosede O.
- Aboubaker Mohamed Houmed
- Abouelhoda Mohamed
- Abouelnaga S.
- Abualas Elamin
- Abubeker Ramalia Chabi
- Abuelenein Ehab Abdelkader
- Abuzaid Nadir
- Abworo Edward O.
- Ada Diosdado Odjama Nseng
- Addidle Michael
- Adegbola Richard
- Adegnika Akim A.
- Adegnika Ayola Akim
- Adel Abd Monaem
- Adeniji Johnson A.
- Adepetun Tomiwa
- Adesegun A.
- Adesuyi Omoare
- Adetifa Ifedayo M. O.
- Adewumi Olubusuyi M.
- Adewumi Oluwatimilehin
- Adewumi Praise
- Adeyemi Kayode T.
- Adhikari Bishwo N.
- Adil El Hamouchi
- Adjiratou Aissatou B. A.
- Adnew Bethlehem
- Adu Bright
- Adu Eric
- Adusei-Poku Mildred
- Agbenyo Seyram Bless
- Agbodzi B.
- Ageez A.M.
- Agoti Charles N.
- Aguenaou Hassan
- Agwa Sara Hassan
- Agweyu Ambrose
- Ahmed El Bara
- Ahmed Elhadi A.
- Ahmed Hatem
- Ahmed M.
- Ahmed O. S.
- Ahmed Rahma
- Ahmed Shymaa S.
- Ahmed Side Mohamed
- Ahmed Yahaya Ali
- Ahouidi Ambroise
- Ahuka-Mundeke Steve
- Ahumibe Anthony
- Ahyong Vida
- Aissam El Aliani
- Ajayi Nnennaya A.
- Ajibaye Solomon
- Ajili F.
- Ajogbasile F.V.
- Ajogbasile Fehintola V.
- Akanbi Olusola Anuoluwapo
- Akenji Blaise MBoringong
- Akhoud Youssef
- Akinola Monilade
- Akogbeto Petas
- Akoua-Koffi Chantal G.
- Akpede George O.
- Al Onifade Fattah
- Alain Etoundi Mballa
- Alaoui Afaf
- Alaoui-Amine Sanaa
- Alarif Ahlam
- Alaruusi A. M.
- Albert Mélanie
- AlEmam Adba Alfatih
- Alemayehu Dawit Hailu
- Alemu Fekadu
- Algheriani Raiva
- Ali Abraham
- Ali M.A.
- Ali Mohamed Ahmed
- Ali Mushal
- Ali Wael
- Alkarim Mona O.A.
- Allam Loubna
- Allam Mushal
- Allam Mushal
- Altamura Settimia
- Amar Narjis
- Amenga-Etego Lucas N.
- Amer K. E.
- Amer Khaled
- Amira Souissi
- Amoako Daniel G.
- Amoo Olufemi Samuel
- Amoth Patrick
- Amougou Marie
- Ampofo William K.
- Amuri Adrienne A.
- Amuzu Dominic S. Y.
- Amzazi Saaïd
- Anang Abraham Kwabena
- Anas Abbad
- Andeko Julia C.
- Andersen Kristian
- Andersson Hana Sofia
- Andika Brian
- Andres Moreira-Soto
- Andriam Soa Fy
- Andriamandimby Soa Fy
- Anga Latifa
- Ange Dossou
- Angelov Angel
- Anna-Lena Sander
- Annajr B.
- Anoh Etilé A.
- Anscombe Catherine
- Antwerpen Markus H.
- Anu Campbell
- Anyaneji Ugochukwu J.
- Anyika Chinyere
- Aouni M.
- Appiah Vincent
- Appiah-Kubi Joyce
- Arena Fabio
- Arjaquah Augustina
- Arjarquah A.
- Armand Edang-Minko
- Armanious Riad Mounir
- Armoo Samuel
- Arnaldo Paulo
- Arnold Catherine E.
- Arrouchi Housna
- Artesi Maria
- Aryeetey Sherihane
- Asamoah Jesse Addo
- Asante Ivy A.
- Asare K.M.
- Ashton Philip
- Ashton Phillip
- Asiedu Ernest
- Asiedu-Bekoe Franklyn Egbe
- Asiimwe Stephen
- Askander Omar
- Asmamaw Kominist
- Assane Hamadi
- Assoumou Samira Zoa
- Atiga N.
- Attiku Keren Okyerebea
- Audu Rosemary A.
- Auld A.
- Awandare Gordon A.
- Awinda George
- Awunyo Sena
- Ayansola Oyeronke
- Ayei James
- Ayekaba Mitoha Ondo’o
- Ayivor-Djanie Reuben
- Aymane Bouzidi
- Ayo-Ale B.
- Ayoade F.
- Ayoola Joy
- Ayouba Ahidjo
- Aziz Ramy Karam
- Aziza Amuri
- Azman Andrew
- Aïssi Melchior A. Joël
- Ba-Diallo Awa
- Babatunde Sunday
- Baboo S. B.
- Badjo Ange
- Badou Yvette
- Bagaya Bernard Ssentalo
- Bah Mamadou Saliou
- Bahadoor B. S.
- Bahnassy A.A.
- Bajjou Tahar
- Baker David
- Baker Noah
- Bakhash Shah Mohamed
- Bakry U.
- Balde Aladje
- Balde Aladje
- Balm Michelle
- Bamourou Diané
- Banda R.
- Bane S.
- Barasa Edwine
- Barbet Marion
- Bareng Ontlametse T.
- Barilar Ivan
- Barkat Amina
- Barnes Kayla
- Barreh Guedi Ali
- Bashein Abdulla
- Bassène Hubert
- Batchi-Bouyou Armel L.
- Batchi-Bouyou Armel L.
- Bates Matthew
- Batra Dhwani
- Batra R.
- Bauer Peter
- Baxter Cheryl
- Bayih Abebe Genetu
- Bbosa Nicholas
- Bedford Trevor
- Bediako Yaw
- Bedié
- Bedri Shahinaz.A.
- Behillil Sylvie
- Bejon Philip
- Belarbi Essia
- Belfquih Bouchra
- Belkhir A.B.
- Bellefquih Abdelkrim Meziane
- Beloufa Mohamed Amine
- Belournou Grace Angong
- Ben Alaya Nissaf
- Ben Ayed I.
- Ben Boubaker Ilhem Boutiba
- Ben Boubaker Ilhem Boutiba
- Ben Kahla Alia
- Ben Khelil Jalila
- Ben Moussa Mohamed
- Ben Othman Roua
- Ben Romdhane Habiba
- Ben Sassi Manel
- Ben Sassi Mouna
- Benaissa Elmostafa
- Benhida Rachid
- Benkeroum Samira
- Benkirane Hasnae
- Bennett Andrew J.
- Benrahma Houda
- Bensaid M.
- Bensalem Aicha
- Benyahia Amel
- Bestehorn-Willmann Malena S.
- Bester Phillip A.
- Beyene Getachew Tesfaye
- Bhiman Jinal N.
- Bighignoli B.
- Bikangui Rodrigue
- Bimouhen Abderrahmane
- Bingono Sam O'neilla Oye
- Biscornet Leon
- Bishop-Lilly Kimberly A.
- Bitew Molalegne
- Bitrou S.M.
- Bizard Méline
- Bióté Simão Tchuda
- Blackmore Timothy
- Blakiston Matt
- Bloomfield Max
- Bnouyahia Ikram
- Boatemaa Linda
- Bolajoko Bankole
- Bonney Evelyn Y.
- Bonney Joseph H. K.
- Bonney Kofi
- Bontems Sébastien
- Bootsma Sacha
- Borrmann Steffen
- Boter Marjan
- Boujemla Bouchra
- Bours Vincent
- Boussoukou Ismael Pierrick Mikelet
- Bouzid Amal
- Bouzid Jawad
- Bracchitta Fiorenza
- Brechar Ludivine
- Bridges Daniel J.
- Briese Thomas
- Brisebarre Angela
- Brook Cara
- Bssaibis Fatna
- Budiaki Sylvie L.
- BUHARI Mikhail Olayinka
- Bulimo Wallace D
- Bunga Sudhir
- Butel Christelle
- Butera Yvan
- Bwogi Josephine
- Camara Alimou
- Camara Makhtar
- Campbell Allan
- Campbell Julian
- Cancino Irving
- Candé Adul
- Capel Camille
- Carey Omondi Francis
- Carniel Elisabeth
- Carr Rosina A. A.
- Carri Valeria Delli
- Carvalho Kevin S.
- Cassama Faatu
- Cedola Donatella
- Cer Regina Z.
- Chabert-Consen Marie Madeleine
- Chabuka L. B.
- Chabuka Lucious
- Chambaro H.
- Chammam Sara
- Chamman Sarra
- Chanda D.
- Changula K.
- Charlene Sonal P.
- Chawech H.
- Chenaoui Mohamed
- Chenwi Collins
- Chestakova Irina
- Chgouri Fatima
- Chilufya C.
- Chilufya Moses
- Chimedza Jasper
- Chinedu Ugwu
- Chipimo P.J.
- Chitanga S.
- Chitechi Esther
- Chitenje M.
- Chiwaula M. J.
- Choga Wonderful T.
- Chouati Taha
- Chouikha Anissa
- Christoffels Alan
- Chtourou A.
- Chukwu Chimaobi
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- Cigolo Jean-Claude Makangara
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- Clarisse Murebwayire
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- Crespin Xavier
- Cá Milanca Agostinho
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- Daghfous Riadh
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- Damaris Matoke-Muhia
- Damena D.
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- Diarra B.
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- Diaw Papa Alassane
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- Dieng Alle Baba
- Dieng Assane
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- Diop Mamadou
- Diop Oumy
- Djimde Abdoulaye
- Djingarey Mamoudou Harouna
- Djomsi Dowbiss Meta
- Djontu Jean Claude
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- Embaló Bubacar Delgado Pinto
- Emna Gaies
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- Raharinosy Vololoniaina
- Rahoui Jalila
- Raimond Petra
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- Tefera D.A.
- Tefera Dessalegn Abeje
- Tegally Houriiyah
- Tegomoh Bryan
- Tegueni Kokou
- Tei-Maya
- Teka Gizaw
- Tembo John
- Tesfaye Abraham
- Tesfaye Gelanew
- Tesfaye Kassahun
- Tessema Sofonias K.
- Testimony Olumade
- Thiam Aminata Sileymane
- Thilliez Gaetan
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- Tia Alie
- Tinto Halidou
- Tollera Getachew
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- Tsiry R.
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- Ulrich M.
- Umumararungu Esperance
- Umuringa Jeanne d’Arc
- Upton Arlo
- Ushijima Yuri
- Ussher James
- Utpatel Christian
- Uwanibe Jessica N.
- Uwituze Arlene
- van der Eijk Annemiek
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- Van Rooyen G.
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- Vanmechelen Bert
- Vanpeene Maud
- Velavan Thirumalaisamy P.
- Venter Marietjie
- Vernet Marie-Astrid
- Viana R.
- Vickos U.
- Victoir Kathleen
- Vida Ahyong
- Vidal Nicole
- Viegas Sofia
- Vincent Grace
- Vinze Anika
- Voegtly Logan J.
- von Gottberg Anne
- Waberi Zeinab Ali
- Wadi Amira Suliaman
- Wadonda N.
- Wadula J.
- Wagner Philipp
- Wahab Kolawole Wasiu
- Waitumbi John
- Walter Mathias C.
- Wamala Joseph F.
- Wandera Dennis N.
- Wang Jing
- Wang Xiuhua
- Wani Gregory
- Wanjohi Dorcas W.
- Wanok Stephen
- Waruhiu C.N.
- Waruhiu Cecilia
- Wasfi Fares
- Watters Chaselynn M.
- Wawina-Bokalanga Tony
- Wayengera Misaki
- Wayoro Oby
- Webby R.
- Webby Richard
- Weldemariam A.G.
- Weldemariam Atsbeha G.
- Werno Anja
- Wiley Michael R.
- Wilkinson David
- Wilkinson Eduan
- Williamson Carolyn
- Wilson Shannon
- Woelfel R.
- Wohl Shirlee
- Wolh S.
- Wolter Nicole
- Wuduri Zara
- Wulf Ben
- Wurie I.
- Wurie Isatta
- Xavier Joicymara S.
- Xiang Zuzheng
- Xie Hong
- Yadouleton Anges
- Yadouleton Yahya
- Yakout Mostfa
- Yandoko Rivalyn Nakoune
- Yang Qi
- Yao Kouadio T.
- Yassine Kasmi
- Yassine Zouheir
- Yasuda Jiro
- Yatassaye Bouna
- Yeboah C.
- Yeboah Richmond
- Yeboah-Manu Dorothy
- Yemi Bright K.
- Yiaba Cyrus
- Yiaba Warren Cyrus
- Yu Popova A.
- Yusuf Nyam Itse
- Yusuf Yacob Mohamed
- Zablon J. Matoke D.
- Zablon J.O.
- Zaher Tarek Refaat Elnagdy Raafat
- Zahra El Ansari Fatima
- Zahran Manal Hamdy
- Zekri Abdel-Rahman N.
- Zhang J.
- Zhou Pei
- Zinyowera Sekesai
- Zong Minko O.
- Zongo Arsène
- Zorgani A.
- Zouaki Amal
- Zulu P.
- Zumla Ali
- Zumla Alimuddin
- Zuze Boitumelo
- Publication venue
- 'American Association for the Advancement of Science (AAAS)'
- Publication date
- 07/10/2022
- Field of study
INTRODUCTION
Investment in Africa over the past year with regard to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing has led to a massive increase in the number of sequences, which, to date, exceeds 100,000 sequences generated to track the pandemic on the continent. These sequences have profoundly affected how public health officials in Africa have navigated the COVID-19 pandemic.
RATIONALE
We demonstrate how the first 100,000 SARS-CoV-2 sequences from Africa have helped monitor the epidemic on the continent, how genomic surveillance expanded over the course of the pandemic, and how we adapted our sequencing methods to deal with an evolving virus. Finally, we also examine how viral lineages have spread across the continent in a phylogeographic framework to gain insights into the underlying temporal and spatial transmission dynamics for several variants of concern (VOCs).
RESULTS
Our results indicate that the number of countries in Africa that can sequence the virus within their own borders is growing and that this is coupled with a shorter turnaround time from the time of sampling to sequence submission. Ongoing evolution necessitated the continual updating of primer sets, and, as a result, eight primer sets were designed in tandem with viral evolution and used to ensure effective sequencing of the virus. The pandemic unfolded through multiple waves of infection that were each driven by distinct genetic lineages, with B.1-like ancestral strains associated with the first pandemic wave of infections in 2020. Successive waves on the continent were fueled by different VOCs, with Alpha and Beta cocirculating in distinct spatial patterns during the second wave and Delta and Omicron affecting the whole continent during the third and fourth waves, respectively. Phylogeographic reconstruction points toward distinct differences in viral importation and exportation patterns associated with the Alpha, Beta, Delta, and Omicron variants and subvariants, when considering both Africa versus the rest of the world and viral dissemination within the continent. Our epidemiological and phylogenetic inferences therefore underscore the heterogeneous nature of the pandemic on the continent and highlight key insights and challenges, for instance, recognizing the limitations of low testing proportions. We also highlight the early warning capacity that genomic surveillance in Africa has had for the rest of the world with the detection of new lineages and variants, the most recent being the characterization of various Omicron subvariants.
CONCLUSION
Sustained investment for diagnostics and genomic surveillance in Africa is needed as the virus continues to evolve. This is important not only to help combat SARS-CoV-2 on the continent but also because it can be used as a platform to help address the many emerging and reemerging infectious disease threats in Africa. In particular, capacity building for local sequencing within countries or within the continent should be prioritized because this is generally associated with shorter turnaround times, providing the most benefit to local public health authorities tasked with pandemic response and mitigation and allowing for the fastest reaction to localized outbreaks. These investments are crucial for pandemic preparedness and response and will serve the health of the continent well into the 21st century
Transposição do enxerto vascularizado da fíbula pro fêmur diafisário sem microanastomoses
- Author
- Publication venue
- Sociedade Brasileira de Ortopedia e Traumatologia
- Publication date
- 01/01/2010
- Field of study
OBJETIVO: O estudo descreve uma maneira nova e simples de transplantar o enxerto ósseo vascularizado da fíbula pro fêmur diafisário sem necessidade de microcirurgia, demonstra o caso clínico operado com bom resultado quanto a vascularização e consolidação óssea e, por último, especula sobre possíveis outras aplicações dentro da cirurgia reconstrutiva. MÉTODOS: A fíbula vascularizada é transportada até o fêmur sem necessidade de microcirurgia, alcançando até sua metáfise proximal através das comunicações das perfurantes do músculo gêmeo lateral com as septais fibulares via retalho de pele póstero-lateral da perna que intersecciona os dois sistemas. RESULTADOS: O paciente operado evoluiu sem infecção. Cintilografia esquelética precoce demonstrou vascularização óssea. CONCLUSÃO: O retalho gêmeo fibular é nova arma no arsenal do cirurgião. Sua técnica é factível, reprodutível, seu tempo cirúrgico reduzido e o princípio de construção com ponte através de ilhas de pele e perfurantes poderá ser aplicado na construção de novos retalhos
Intraoperative ventilator settings and their association with postoperative pulmonary complications in neurosurgical patients: post-hoc analysis of LAS VEGAS study
- Author
- Adeline Gerard
- Adem Bytyqi
- Aggeliki Pandazi
- Agreta Gecaj-Gashi
- Ahmed Abdel-Razek
- Ahmed Chishti
- Ahmed Gouda Ahmed
- Ahmed Mostafa El-Shaarawy
- Alar Sormus
- Alastair Rose
- Albert Prades
- Alberto Lisi
- Alberto Zangrillo
- Aleksandra Lazukic
- Alena Breidablik
- Alenka Spindler-Vesel
- Alessandro Bacuzzi
- Alexander Kulikov
- Alexander Lugovoy
- Alexandre Molin
- Alexandru Bogdan Prodan
- Alexey Gritsan
- Alexey Ovezov
- Ali Saltali
- Alice Werger
- Alida Moise
- Alistair Cain
- Alyson Andrew
- Amanda Datson
- Ambra Licia Di Parma
- Amir Rafi
- Amir Shafi-Kabiri
- Ana de Abajo Larriba
- Ana Fernandez-Bustamante
- Ana Maria Petcu
- Ana Pekle-Golez
- Ana Ricardo
- Andre Gottschalk
- Andrea Bell
- Andrea Brunelli
- Andrea Cortegiani
- Andreas Gueldner
- Andreas Reske
- Andrew Donovan
- Andrey Babayants
- Andrey Lubnin
- Andriy Grynyuk
- Andriy Mazur
- Anette Bundy
- Angela Almagro
- Angela Monteirosa
- Angelo Gratarola
- Ann De Bruyne
- Anna Fouracres
- Anna Marija Pavicic
- Annamaria Campanile
- Anne Duvekot
- Annika Aun
- Antoine Petit
- Antonella Marrella
- Antonino Giarratano
- Antonio Martínez Simon
- Antonio Zilic
- Antonis Andreou
- Arieh Eden
- Ashok Das
- Ashok Raj
- Audrey Pospiech
- Aurika Karbonskiene
- Bahar Kuvaki
- Ball L
- Barbka Novak-Supe
- Bas In 't Veld
- Battaglini D
- Baturay Kansu Kazbek
- Bea Bastin
- Ben Creagh-Brown
- Ben Schwerdtfeger
- Ben Shelley
- Benedikt Pannen
- Benoit Plichon
- Bernhard Urbanek
- Bjorn Heyse
- Bluth T
- Branka Maldini
- Branka Mazul-Sunko
- Branka Strazisar
- Branwen Ellison
- Brigitte Leva
- Cait Goodall
- Canet J
- Carlo Alberto Volta
- Carlos Ferrando
- Carlos Puigbo
- Catalin-Traian Guran
- Caterina Valeria Pesce
- Ceren Sanlikarip
- Cesar Aldecoa Alvares-Santullano
- Charley Higham
- Charlotte Severijns
- Christa Boer
- Christian Nestler
- Christopher Uhlig
- Christos Nouris
- Chryssa Pourzitaki
- Claire West
- Clare Jackson
- Colin Barrett
- Concezione Tommasino
- Corrado Liperi
- Cristina Saiz Ruiz
- Dalip Muhardri
- Dan Corneci
- Dan Costea
- Dana Tomescu
- Daniel Ferreira
- Daniela Filipescu
- Daniela La Bella
- Daniele Sances
- Danielle Franklin
- Darija Azenic-Venzera
- Daryl Kor
- David Kahn
- David Portch
- David Rogerson
- Davide D'antini
- Debbie Fuller
- Deborah Clements
- Dejana Djonoviċ-Omanoviċ
- Demet Sulemanji
- Denny Tran Thiem
- Diana Westerheide
- Dimitri Dylst
- Dimitrios Valsamidis
- Dimitris Karapanos
- Diogo Martins
- Dmitri Bystritski
- Dubravka Ivic
- Dunja Mihajlovic
- Egle Kontrimaviciute
- Eiko Herodes
- Elaine Rogers
- Elena Sardo
- Elisa Brugnoni
- Elisabeth Andersson
- Elizabeth Homan
- Elizabeth Luzier
- Emily Calton
- Emmanuel Futier
- Emmanuel Marret
- Emre Camci
- Enrique Moret
- Erick Morais
- Erika Salciute
- Ernesto Pastor
- Eyup Aydogan
- Fatma Mine Karaman
- Fatma Nur Akgun
- Fatos Sada
- Federica Scavonetto
- Felicity Mackenzie
- Ferim Gunenc
- Fernande Lois
- Fevzi Toraman
- Filippo Bressan
- Foteini Zafeiropoulou
- Francesca Montalto
- Francesca Rapido
- Francesco Bona
- Francis Joseph Borg
- Francisco Hidalgo Martinez
- Frederic Rodenas
- Frode Fjellanger
- Gabija Tomkute
- Gabriela Droc
- Gabriele Sales
- Galina Gritsan
- Gama de Abreu M
- Gary Mills
- Gary Minto
- Georgia Tsaousi
- Georgios Antholopoulos
- Georgios Gkiokas
- Gerd Struber
- Gianluca Castellani
- Gianluca Spano
- Gianmarco Giacoletto
- Gilda Cinnella
- Giorgia Cerati
- Giovanni Landoni
- Gisela Perez
- Giulia Pellerano
- Giuseppe Musella
- Giuseppe Servillo
- Glória Tareco
- Gorjana Erceg
- Guy Rousseau
- Hana Harazim
- Hans Gombotz
- Hany Yassin
- Helen Nutt
- Helen Roberts
- Helen Scholes
- Helfried Metzler
- Hemmes SNT
- Hermann Wrigge
- Hiesmayr M
- Hisham Hosny Abdelwahab
- Hollmann MW
- Hrvoje Vinkovic
- Ib Jammer
- Ines Arpino
- Inga Mladic-Batinica
- Ioana Cristina Grintescu
- Ioana Marina Grintescu
- Ioana Popescu Garotescu
- Iole Brunetti
- Iorel Gherghina
- Irene Wiersma
- Irina Grosu
- Irina Komissarova
- Iulia Cindea
- Ivan Kostadinov
- Ivan Mirkovic
- Ivana Oputric
- Ivana Volfova
- Jaber S
- Jadranka Pavicic Saric
- Jale Maral
- James Limb
- Jan Binnekade
- Jan Brujevic
- Jan Poelaert
- Jane Montgomery
- Janet Palmer
- Jannicke Mellin-Olsen
- Jasmina Markovic-Bozic
- Jasmina Pejakovic
- Jasminka Kopic
- Jasper De Jong
- Jaume Canet
- Jayne Foot
- Jaysimha Susarla
- Jens Hering
- Jens Krassler
- Jeroen van Melkebeek
- Jesus Rico
- Jill Deane
- Joana Amaral
- Johann Geib
- John Williams
- John Xuereb
- Jonathan Paddle
- Jose Antonio de Andrés Ibañez
- Jose Tatay Vivo
- Josep Fava
- Josip Zunic
- Julie Colley
- Juraj Sprung
- Jurgen Van Limmen
- Juri Karjagin
- Juri Oganjan
- Kaili Sarapuu
- Kamil Hudacek
- Karen Simeson
- Karginova Zalina
- Kassiani Theodoraki
- Katarina Bruncakova
- Katarina Liskova
- Katerina Jirmanova
- Katerina Vitkova
- Katharina Skirstad Hodt
- Kazimir Juricic
- Konstantinos Stroumpoulis
- Krishnan Kodaganallur
- Lars Gillberg
- Laura Pasin
- Laura Pistidda
- Leanne Welch
- Lenka Polakovicova
- Lieuwe Bos
- Liliana Mirea
- Lisa Wayman
- Luc De Baerdemaeker
- Luca Brazzi
- Luca Montagnani
- Lucia Mirabella
- Lucia Stancombe
- Lucia Zamidei
- Lucian Horhota
- Lucy Brown
- Luigi Beretta
- Luigi Delunas
- Luigi Giancarlo
- Luiz Fernando
- Lynn Everett
- Madalina Dutu
- Magda Riciu
- Mahdy Abdelhady
- Maka Zuleika
- Manuel Granell
- Manuel Vico Avalos
- Mar Sendra
- Marc Solier
- Marcel Gama de Abreu
- Marco Baciarello
- Marco Venturino
- Marco Verri
- Marcos Vidal Melo
- Marcus Schultz
- Margaret Szewczyk
- Mari Carmen Unzueta
- Maria de Lurdes Goncalves Castro
- Maria Jose Yepes Temino
- Maria Nadolski
- Maria Vargas
- Maria Zelinkova
- Marian Irinel Tudoroiu
- Mariana Correia
- Marie-Claire van Malderen
- Marina Juros-Zovko
- Marina Soro
- Mario Defez
- Marios-Konstantinos Tasoulis
- Mark Pulletz
- Markus Hollmann
- Marta Eugenia Sassone
- Martin Scharffenberg
- Martin Weiss
- Martina Kosinova
- Matea Bogdanovic Dvorscak
- Matthew Rucklidge
- Maud Beran
- Maudrian Burton
- Maureen Bezzina
- Maurizio Solca
- Maximilian Schaefer
- Merilin Mall
- Michael Hiesmayr
- Michael Lundberg
- Michal Drab
- Michela Generali
- Michele De Michele
- Mihai Popescu
- Mihaly Veres
- Mills GH
- Minca Voje
- Mine Yildiz
- Mirja Konrad
- Mirna Sehovic
- Miroljub Jovanov
- Mladen Carev
- Mohamed Magdy
- Mohamed Mahran
- Mona Momeni
- Monir Jawad
- Moses Chikungwa
- Mrutyunjaya Rambhatla
- Murat Yilmaz
- Mónica Rodriguez Nunez
- Natalia Anipchenko
- Natasa Dropulic
- Nathalie Roels
- Necmiye Hadimioglu
- Nenad Karanovic
- Nesil Coskunfirat
- Neval Boztug
- Nicholas Boyd
- Nukhet Sivrikoz
- Nuzhet Mert Senturk
- Oguzhan Arun
- Oleg Korolkov
- Olga Smekalova
- Onur Selvi
- Otto Mohr
- Ozgur Senturk
- Pablo Monedero
- Panagiota Florou
- Paola Morelli
- Paolo Pelosi
- Paolo Severgnini
- Parizade Raymode
- Pasquale Raimondo
- Patrice Forget
- Paul Dennesen
- Paula Dzurnakova
- Pauline Mercer
- Pavel Prokoshev
- Peeter Kivik
- Pelosi P
- Petar Miskovic
- Peter Carvalho
- Peter Kienbaum
- Peter Spieth
- Petr Stourac
- Philip Watt
- Philipp Simon
- Piet Wyffels
- Povilas Miliauskas
- Putensen C
- Rachel Walker
- Radek Filipsky
- Radovan Dudas
- Raquel Martinez
- Renatas Tikuisis
- Reuven Pizov
- Riccardo Ragazzi
- Rienk van Beek
- Robba C
- Roberto Dossi
- Roberto Zoppellari
- Rocio Perez
- Rosanna Sileo
- Ruby Molina
- Rupert Pearse
- Ruta Aukstakalniene
- Ruxandra Copotoiu
- Ruxandra Fota
- Sabrine Hemmes
- Salvatore Grasso
- Samir El Kafrawy
- Samir Jaber
- Sanda-Maria Copotoiu
- Sandeep Kusre
- Sandeep Varma
- Sandrine Damster
- Santi Maurizio Raineri
- Sara Rodrigues
- Sara Sher
- Sarah Gibb
- Sarah Moreton
- Savino Spadaro
- Schmid W
- Schultz MJ
- Selma Pernar
- Semih Kucukguclu
- Semra Kucukgoncu
- Septimiu Gheorghe Moldovan
- Sergei Fedorov
- Sergiy Vorotyntsev
- Serpa Neto A
- Serpil Ustalar Ozgen
- Severgnini P
- Seyda Canli
- Shivarajan Algarsamy
- Silvius Negoita
- Simon Davies
- Simone Merzky
- Sipylaite Jurate
- Slavica Kvolik
- Sofia Appleton
- Sonja Skiljic
- Sopio Peradze
- Stanley Wutai
- Stefan de Hert
- Stefan Ivars
- Stefano Pezzatto
- Stefano Tredici
- Stephanie Jones
- Stephen Mowat
- Stijn van de Velde
- Suat Sanli
- Sudhakar Marri
- Suresh Venkatesh
- Susan Yates
- Susana Cadilha
- Suzana Parente
- Tanja Goranovic
- Tanja Treschan
- Tarek Metwally
- Tatiana Sidiropoulou
- Tatyana Kapkan
- Thais Creary
- Thea Koch
- Thomas Bluth
- Thomas Kiss
- Thomas Smith
- Thomas Wegscheider
- Toby Weingarten
- Tom Jacobs
- Tomas Kolacek
- Tomislav Radocaj
- Valentina Tarzia
- Valery Likhvantsev
- Vedran Frkovic
- Veerle van Mossevelde
- Vesna Novak-Jankovic
- Vicari Sottosanti
- Victoria Barsan
- Victoria Moral
- Vidal Melo MF
- Villiam Sobona
- Vincenzo Russotto
- Vittoria Bartolini
- Wael Fathy Hasan
- Werner Schmid
- Wolfgang Kroell
- Wrigge H
- Yeo Tze
- Yigal Leykin
- Yousif Saeed
- Zeljka Gavranovic
- Zerrin Sungur
- Zivile Teberaite
- Zsolt Tolcser
- Zuleyha Kazak Bengisun
- Zuzana Kusnierikova
- Şule Ozbilgin
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2020
- Field of study
Background: Limited information is available regarding intraoperative ventilator settings and the incidence of postoperative pulmonary complications (PPCs) in patients undergoing neurosurgical procedures. The aim of this post-hoc analysis of the 'Multicentre Local ASsessment of VEntilatory management during General Anaesthesia for Surgery' (LAS VEGAS) study was to examine the ventilator settings of patients undergoing neurosurgical procedures, and to explore the association between perioperative variables and the development of PPCs in neurosurgical patients.
Methods: Post-hoc analysis of LAS VEGAS study, restricted to patients undergoing neurosurgery. Patients were stratified into groups based on the type of surgery (brain and spine), the occurrence of PPCs and the assess respiratory risk in surgical patients in Catalonia (ARISCAT) score risk for PPCs.
Results: Seven hundred eighty-four patients were included in the analysis; 408 patients (52%) underwent spine surgery and 376 patients (48%) brain surgery. Median tidal volume (VT) was 8 ml [Interquartile Range, IQR = 7.3-9] per predicted body weight; median positive end-expiratory pressure (PEEP) was 5 [3 to 5] cmH20. Planned recruitment manoeuvres were used in the 6.9% of patients. No differences in ventilator settings were found among the sub-groups. PPCs occurred in 81 patients (10.3%). Duration of anaesthesia (odds ratio, 1.295 [95% confidence interval 1.067 to 1.572]; p = 0.009) and higher age for the brain group (odds ratio, 0.000 [0.000 to 0.189]; p = 0.031), but not intraoperative ventilator settings were independently associated with development of PPCs.
Conclusions: Neurosurgical patients are ventilated with low VT and low PEEP, while recruitment manoeuvres are seldom applied. Intraoperative ventilator settings are not associated with PPCs
Association between night-time surgery and occurrence of intraoperative adverse events and postoperative pulmonary complications
- Author
- Abdel-Razek Ahmed
- Abdelhady Mahdy
- Abdelwahab Hisham Hosny
- Ahmed Ahmed Gouda
- Akgun Fatma Nur
- Aldecoa Alvares-Santullano Cesar
- Algarsamy Shivarajan
- Almagro Angela
- Amaral Joana
- Andersson Elisabeth
- Andreou Antonis
- Andrew Alyson
- Anipchenko Natalia
- Antholopoulos Georgios
- Appleton Sofia
- Arpino Ines
- Arun Oguzhan
- Aukstakalniene Ruta
- Aun Annika
- Avalos Manuel Vico
- Aydogan Eyup
- Azenic-Venzera Darija
- Babayants Andrey
- Baciarello Marco
- Bacuzzi Alessandro
- Ball L
- Barrett Colin
- Barsan Victoria
- Bartolini Vittoria
- Bastin Bea
- Bell Andrea
- Bengisun Zuleyha Kazak
- Beran Maud
- Beretta Luigi
- Bezzina Maureen
- Binnekade Jan
- Bluth Thomas
- Boer Christa
- Bona Francesco
- Borg Francis Joseph
- Bos Lieuwe
- Boyd Nicholas
- Boztug Neval
- Brazzi Luca
- Breidablik Alena
- Bressan Filippo
- Brown Lucy
- Brugnoni Elisa
- Brujevic Jan
- Bruncakova Katarina
- Brunelli Andrea
- Brunetti Iole
- Bundy Anette
- Burton Maudrian
- Bystritski Dmitri
- Bytyqi Adem
- Cadilha Susana
- Cain Alistair
- Calton Emily
- Camci Emre
- Campanile Annamaria
- Canet J
- Canli Seyda
- Carev Mladen
- Carmen Unzueta Mari
- Carvalho Peter
- Castellani Gianluca
- Cerati Giorgia
- Chikungwa Moses
- Chishti Ahmed
- Cindea Iulia
- Cinnella Gilda
- Clements Deborah
- Colley Julie
- Copotoiu Ruxandra
- Copotoiu Sanda-Maria
- Corneci Dan
- Correia Mariana
- Cortegiani A
- Coskunfirat Nesil
- Costea Dan
- Creagh-Brown Ben
- Creary Thais
- D'antini Davide
- Damster Sandrine
- Das Ashok
- Datson Amanda
- Davies Simon
- de Abajo Larriba Ana
- de Andres Ibanez Jose Antonio
- De Baerdemaeker Luc
- De Bruyne Ann
- De Hert Stefan
- De Jong Jasper
- De Michele Michele
- Deane Jill
- Defez Mario
- Delunas Luigi
- Dennesen Paul
- Di Parma Ambra Licia
- Djonovic-Omanovic Dejana
- Donovan Andrew
- Dossi Roberto
- Drab Michal
- Droc Gabriela
- Dropulic Natasa
- Dudas Radovan
- Dutu Madalina
- Duvekot Anne
- Dvorscak Matea Bogdanovic
- Dylst Dimitri
- Dzurnakova Paula
- Eden Arieh
- el Kafrawy Samir
- El-Shaarawy Ahmed Mostafa
- Ellison Branwen
- Erceg Gorjana
- Everett Lynn
- Fava Josep
- Fedorov Sergei
- Fernandez-Bustamante Ana
- Fernando Luiz
- Ferrando Carlos
- Ferreira Daniel
- Filipescu Daniela
- Filipsky Radek
- Fjellanger Frode
- Florou Panagiota
- Foot Jayne
- Forget Patrice
- Fota Ruxandra
- Fouracres Anna
- Franklin Danielle
- Frkovic Vedran
- Fuller Debbie
- Futier Emmanuel
- Gama de Abreu M
- Garotescu Ioana Popescu
- Gavranovic Zeljka
- Gecaj-Gashi Agreta
- Geib Johann
- Generali Michela
- Gerard Adeline
- Gherghina Iorel
- Giacoletto Gianmarco
- Giarratano Antonino
- Gibb Sarah
- Gillberg Lars
- Gkiokas Georgios
- Gombotz Hans
- Goncalves Castro Maria de Lurdes
- Goodall Cait
- Goranovic Tanja
- Gottschalk Andre
- Granell Manuel
- Grasso Salvatore
- Gratarola Angelo
- Gregoretti C
- Grintescu Ioana Cristina
- Grintescu Ioana Marina
- Gritsan Alexey
- Gritsan Galina
- Grosu Irina
- Grynyuk Andriy
- Gueldner Andreas
- Gunenc Ferim
- Guran Catalin-Traian
- Hadimioglu Necmiye
- Harazim Hana
- Hasan Wael Fathy
- Hemmes Sabrine
- Hemmes SNT
- Hering Jens
- Herodes Eiko
- Heyse Bjorn
- Hidalgo Martinez Francisco
- Hiesmayr M
- Hiesmayr Michael
- Higham Charley
- Hodt Katharina Skirstad
- Hollmann Markus
- Hollmann MW
- Homan Elizabeth
- Horhota Lucian
- Hudacek Kamil
- in 't Veld Bas
- Ivars Stefan
- Ivic Dubravka
- Jaber Samir
- Jackson Clare
- Jacobs Tom
- Jammer Ib
- Jawad Monir
- Jirmanova Katerina
- Jones Stephanie
- Jovanov Miroljub
- Jurate Sipylaite
- Juricic Kazimir
- Juros-Zovko Marina
- Kahn David
- Kapkan Tatyana
- Karaman Fatma Mine
- Karanovic Nenad
- Karapanos Dimitris
- Karbonskiene Aurika
- Karjagin Juri
- Kazbek Baturay Kansu
- Kienbaum Peter
- Kiss Thomas
- Kivik Peeter
- Koch Thea
- Kodaganallur Krishnan
- Kolacek Tomas
- Komissarova Irina
- Konrad Mirja
- Kontrimaviciute Egle
- Kopic Jasminka
- Kor Daryl
- Korolkov Oleg
- Kosinova Martina
- Kostadinov Ivan
- Krassler Jens
- Kroell Wolfgang
- Kucukgoncu Semra
- Kucukguclu Semih
- Kulikov Alexander
- Kusnierikova Zuzana
- Kusre Sandeep
- Kuvaki Bahar
- Kvolik Slavica
- La Bella Daniela
- Landoni Giovanni
- Lazukic Aleksandra
- Leva Brigitte
- Leykin Yigal
- Likhvantsev Valery
- Limb James
- Liperi Corrado
- Lisi Alberto
- Liskova Katarina
- Lois Fernande
- Lubnin Andrey
- Lugovoy Alexander
- Lundberg Michael
- Luzier Elizabeth
- Mackenzie Felicity
- Magdy Mohamed
- Mahran Mohamed
- Maldini Branka
- Mall Merilin
- Maral Jale
- Markovic-Bozic Jasmina
- Marrella Antonella
- Marret Emmanuel
- Marri Sudhakar
- Martinez Simon Antonio
- Martinez Raquel
- Martins Diogo
- Mazul-Sunko Branka
- Mazur Andriy
- Mellin-Olsen Jannicke
- Melo Marcos Vidal
- Melo MFV
- Mercer Pauline
- Merzky Simone
- Metwally Tarek
- Metzler Helfried
- Mihajlovic Dunja
- Miliauskas Povilas
- Mills Gary
- Mills GH
- Minto Gary
- Mirabella Lucia
- Mirea Liliana
- Mirkovic Ivan
- Miskovic Petar
- Mladic-Batinica Inga
- Mohr Otto
- Moise Alida
- Moldovan Septimiu Gheorghe
- Molin Alexandre
- Molina Ruby
- Momeni Mona
- Monedero Pablo
- Montagnani Luca
- Montalto Francesca
- Monteirosa Angela
- Montgomery Jane
- Morais Erick
- Moral Victoria
- Morelli Paola
- Moret Enrique
- Moreton Sarah
- Mowat Stephen
- Muhardri Dalip
- Musella Giuseppe
- Nadolski Maria
- Negoita Silvius
- Nestler Christian
- Neto AS
- Nouris Christos
- Novak-Jankovic Vesna
- Novak-Supe Barbka
- Nutt Helen
- Oganjan Juri
- Oputric Ivana
- Ovezov Alexey
- Ozbilgin Sule
- Ozgen Serpil Ustalar
- Paddle Jonathan
- Palmer Janet
- Pandazi Aggeliki
- Pannen Benedikt
- Parente Suzana
- Pasin Laura
- Pastor Ernesto
- Pavicic Anna Marija
- Pearse Rupert
- Pejakovic Jasmina
- Pekle-Golez Ana
- Pellerano Giulia
- Pelosi P
- Peradze Sopio
- Perez Gisela
- Perez Rocio
- Pernar Selma
- Pesce Caterina Valeria
- Petcu Ana Maria
- Petit Antoine
- Pezzatto Stefano
- Pistidda Laura
- Pizov Reuven
- Plichon Benoit
- Poelaert Jan
- Polakovicova Lenka
- Popescu Mihai
- Portch David
- Pospiech Audrey
- Pourzitaki Chryssa
- Prades Albert
- Prodan Alexandru Bogdan
- Prokoshev Pavel
- Puigbo Carlos
- Pulletz Mark
- Putensen C
- Radocaj Tomislav
- Rafi Amir
- Ragazzi Riccardo
- Raimondo Pasquale
- Raineri Santi Maurizio
- Raj Ashok
- Rambhatla Mrutyunjaya
- Rapido Francesca
- Raymode Parizade
- Reske Andreas
- Ricardo Ana
- Riciu Magda
- Rico Jesus
- Roberts Helen
- Rodenas Frederic
- Rodrigues Sara
- Rodriguez Nunez Monica
- Roels Nathalie
- Rogers Elaine
- Rogerson David
- Rose Alastair
- Rousseau Guy
- Rucklidge Matthew
- Russotto Vincenzo
- Sada Fatos
- Saeed Yousif
- Saiz Ruiz Cristina
- Salciute Erika
- Sales Gabriele
- Saltali Ali
- Sances Daniele
- Sanli Suat
- Sanlikarip Ceren
- Sarapuu Kaili
- Sardo Elena
- Saric Jadranka Pavicic
- Sassone Marta Eugenia
- Scavonetto Federica
- Schaefer Maximilian
- Scharffenberg Martin
- Schmid W
- Schmid Werner
- Scholes Helen
- Schultz Marcus
- Schultz MJ
- Schwerdtfeger Ben
- Sehovic Mirna
- Selvi Onur
- Sendra Mar
- Senturk Nuzhet Mert
- Senturk Ozgur
- Servillo Giuseppe
- Severgnini P
- Severgnini Paolo
- Severijns Charlotte
- Shafi-Kabiri Amir
- Shelley Ben
- Sher Sara
- Sidiropoulou Tatiana
- Sileo Rosanna
- Simeson Karen
- Simon Philipp
- Sivrikoz Nukhet
- Skiljic Sonja
- Smekalova Olga
- Smith Thomas
- Sobona Villiam
- Solca Maurizio
- Solier Marc
- Sormus Alar
- Soro Marina
- Sottosanti Luigi Giancarlo Vicari
- Spadaro Savino
- Spano Gianluca
- Spieth Peter
- Spindler-Vesel Alenka
- Sprung Juraj
- Stancombe Lucia
- Stourac Petr
- Strazisar Branka
- Stroumpoulis Konstantinos
- Struber Gerd
- Sulemanji Demet
- Sungur Zerrin
- Susarla Jaysimha
- Szewczyk Margaret
- Tareco Gloria
- Tarzia Valentina
- Tasoulis Marios-Konstantinos
- Tatay Vivo Jose
- Teberaite Zivile
- Theodorak Kassiani
- Thiem Denny Tran
- Tikuisis Renatas
- Tolcser Zsolt
- Tomescu Dana
- Tomkute Gabija
- Tommasino Concezione
- Toraman Fevzi
- Tredici Stefano
- Treschan Tanja
- Tsaousi Georgia
- Tudoroiu Marian Irinel
- Tze Yeo
- Uhlig Christopher
- Urbanek Bernhard
- Valsamidis Dimitrios
- van Beek Rienk
- van de Velde Stijn
- Van Limmen Jurgen
- van Malderen Marie-Claire
- van Melkebeek Jeroen
- van Mossevelde Veerle
- Vargas Maria
- Varma Sandeep
- Venkatesh Suresh
- Venturino Marco
- Veres Mihaly
- Verri Marco
- Vinkovic Hrvoje
- Vitkova Katerina
- Voje Minca
- Volfova Ivana
- Volta Carlo Alberto
- Vorotyntsev Sergiy
- Walker Rachel
- Watt Philip
- Wayman Lisa
- Wegscheider Thomas
- Weingarten Toby
- Weiss Martin
- Welch Leanne
- Werger Alice
- West Claire
- Westerheide Diana
- Wiersma Irene
- Williams John
- Wrigge H
- Wrigge Hermann
- Wutai Stanley
- WYFFELS PIET
- Xuereb John
- Yassin Hany
- Yates Susan
- Yepes Temino Maria Jose
- Yildiz Mine
- Yilmaz Murat
- Zafeiropoulou Foteini
- Zalina Karginova
- Zamidei Lucia
- Zangrillo Alberto
- Zelinkova Maria
- Zilic Antonio
- Zoppellari Roberto
- Zuleika Maka
- Zunic Josip
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2019
- Field of study
Background: The aim of this post hoc analysis of a large cohort study was to evaluate the association between night-time surgery and the occurrence of intraoperative adverse events (AEs) and postoperative pulmonary complications (PPCs).
Methods: LAS VEGAS (Local Assessment of Ventilatory Management During General Anesthesia for Surgery) was a prospective international 1-week study that enrolled adult patients undergoing surgical procedures with general anaesthesia and mechanical ventilation in 146 hospitals across 29 countries. Surgeries were defined as occurring during 'daytime' when induction of anaesthesia was between 8: 00 AM and 7: 59 PM, and as 'night-time' when induction was between 8: 00 PM and 7: 59 AM.
Results: Of 9861 included patients, 555 (5.6%) underwent surgery during night-time. The proportion of patients who developed intraoperative AEs was higher during night-time surgery in unmatched (43.6% vs 34.1%; P<0.001) and propensity-matched analyses (43.7% vs 36.8%; P = 0.029). PPCs also occurred more often in patients who underwent night-time surgery (14% vs 10%; P = 0.004) in an unmatched cohort analysis, although not in a propensity-matched analysis (13.8% vs 11.8%; P = 0.39). In a multivariable regression model, including patient characteristics and types of surgery and anaesthesia, night-time surgery was independently associated with a higher incidence of intraoperative AEs (odds ratio: 1.44; 95% confidence interval: 1.09-1.90; P = 0.01), but not with a higher incidence of PPCs (odds ratio: 1.32; 95% confidence interval: 0.89-1.90; P = 0.15).
Conclusions: Intraoperative adverse events and postoperative pulmonary complications occurred more often in patients undergoing night-time surgery. Imbalances in patients' clinical characteristics, types of surgery, and intraoperative management at night-time partially explained the higher incidence of postoperative pulmonary complications, but not the higher incidence of adverse events
Intraoperative ventilator settings and their association with postoperative pulmonary complications in neurosurgical patients: Post-hoc analysis of LAS VEGAS study
- Author
- Abdel-Razek Ahmed
- Abdelhady Mahdy
- Abdelwahab Hisham Hosny
- Ahmed Ahmed Gouda
- Akgun Fatma Nur
- Algarsamy Shivarajan
- Almagro Angela
- Alvares-Santullano Cesar Aldecoa
- Amaral Joana
- Andersson Elisabeth
- Andreou Antonis
- Andrew Alyson
- Anipchenko Natalia
- Antholopoulos Georgios
- Appleton Sofia
- Arpino Ines
- Arun Oguzhan
- Aukstakalniene Ruta
- Aun Annika
- Avalos Manuel Vico
- Aydogan Eyup
- Azenic-Venzera Darija
- Babayants Andrey
- Baciarello Marco
- Bacuzzi Alessandro
- Ball Lorenzo
- Barrett Colin
- Barsan Victoria
- Bartolini Vittoria
- Bastin Bea
- Battaglini Denise
- Bell Andrea
- Bengisun Zuleyha Kazak
- Beran Maud
- Beretta Luigi
- Bezzina Maureen
- Binnekade Jan
- Bluth Thomas
- Bluth Thomas
- Boer Christa
- Bona Francesco
- Borg Francis Joseph
- Bos Lieuwe
- Boyd Nicholas
- Boztug Neval
- Brazzi Luca
- Breidablik Alena
- Bressan Filippo
- Brown Lucy
- Brugnoni Elisa
- Brujevic Jan
- Bruncakova Katarina
- Brunelli Andrea
- Brunetti Iole
- Bundy Anette
- Burton Maudrian
- Bystritski Dmitri
- Bytyqi Adem
- Cadilha Susana
- Cain Alistair
- Calton Emily
- Camci Emre
- Campanile Annamaria
- Canet Jaume
- Canet Jaume
- Canli Seyda
- Carev Mladen
- Carvalho Peter
- Castellani Gianluca
- Cerati Giorgia
- Chikungwa Moses
- Chishti Ahmed
- Cindea Iulia
- Cinnella Gilda
- Clements Deborah
- Colley Julie
- Copotoiu Ruxandra
- Copotoiu Sanda-Maria
- Corneci Dan
- Correia Mariana
- Cortegiani Andrea
- Coskunfirat Nesil
- Costea Dan
- Creagh-Brown Ben
- Creary Thais
- D'Antini Davide
- Damster Sandrine
- Das Ashok
- Datson Amanda
- Davies Simon
- de Abajo Larriba Ana
- de Abreu Marcel Gama
- de Andrés Ibañez Jose Antonio
- de Baerdemaeker Luc
- de Bruyne Ann
- de Hert Stefan
- de Jong Jasper
- de Lurdes Goncalves Castro Maria
- de Michele Michele
- Deane Jill
- Defez Mario
- Delunas Luigi
- Dennesen Paul
- di Parma Ambra Licia
- Djonoviċ-Omanoviċ Dejana
- Donovan Andrew
- Dossi Roberto
- Drab Michal
- Droc Gabriela
- Dropulic Natasa
- Dudas Radovan
- Dutu Madalina
- Duvekot Anne
- Dvorscak Matea Bogdanovic
- Dylst Dimitri
- Dzurnakova Paula
- Eden Arieh
- el Kafrawy Samir
- el-Shaarawy Ahmed Mostafa
- Ellison Branwen
- Erceg Gorjana
- Everett Lynn
- Fava Josep
- Fedorov Sergei
- Fernandez-Bustamante Ana
- Fernando Luiz
- Ferrando Carlos
- Ferreira Daniel
- Filipescu Daniela
- Filipsky Radek
- Fjellanger Frode
- Florou Panagiota
- Foot Jayne
- Forget Patrice
- Fota Ruxandra
- Fouracres Anna
- Franklin Danielle
- Frkovic Vedran
- Fuller Debbie
- Futier Emmanuel
- Gama de Abreu Marcelo
- Garotescu Ioana Popescu
- Gavranovic Zeljka
- Gecaj-Gashi Agreta
- Geib Johann
- Generali Michela
- Gerard Adeline
- Gherghina Iorel
- Giacoletto Gianmarco
- Giancarlo Luigi
- Giarratano Antonino
- Gibb Sarah
- Gillberg Lars
- Gkiokas Georgios
- Gombotz Hans
- Goodall Cait
- Goranovic Tanja
- Gottschalk Andre
- Granell Manuel
- Grasso Salvatore
- Gratarola Angelo
- Grintescu Ioana Cristina
- Grintescu Ioana Marina
- Gritsan Alexey
- Gritsan Galina
- Grosu Irina
- Grynyuk Andriy
- Gueldner Andreas
- Gunenc Ferim
- Guran Catalin-Traian
- Hadimioglu Necmiye
- Harazim Hana
- Hasan Wael Fathy
- Hemmes Sabrine
- Hemmes Sabrine N. T.
- Hering Jens
- Herodes Eiko
- Heyse Bjorn
- Hiesmayr Michael
- Hiesmayr Michael
- Higham Charley
- Hodt Katharina Skirstad
- Hollmann M. Wiersma
- Hollmann Markus
- Homan Elizabeth
- Horhota Lucian
- Hudacek Kamil
- in 't Veld Bas
- Ivars Stefan
- Ivic Dubravka
- Jaber Samir
- Jaber Samir
- Jackson Clare
- Jacobs Tom
- Jammer Ib
- Jawad Monir
- Jirmanova Katerina
- Jones Stephanie
- Jovanov Miroljub
- Jurate Sipylaite
- Juricic Kazimir
- Juros-Zovko Marina
- Kahn David
- Kapkan Tatyana
- Karaman Fatma Mine
- Karanovic Nenad
- Karapanos Dimitris
- Karbonskiene Aurika
- Karjagin Juri
- Kazbek Baturay Kansu
- Kienbaum Peter
- Kiss Thomas
- Kivik Peeter
- Koch Thea
- Kodaganallur Krishnan
- Kolacek Tomas
- Komissarova Irina
- Konrad Mirja
- Kontrimaviciute Egle
- Kopic Jasminka
- Kor Daryl
- Korolkov Oleg
- Kosinova Martina
- Kostadinov Ivan
- Krassler Jens
- Kroell Wolfgang
- Kucukgoncu Semra
- Kucukguclu Semih
- Kulikov Alexander
- Kusnierikova Zuzana
- Kusre Sandeep
- Kuvaki Bahar
- Kvolik Slavica
- la Bella Daniela
- Landoni Giovanni
- Lazukic Aleksandra
- Leva Brigitte
- Leykin Yigal
- Likhvantsev Valery
- Limb James
- Liperi Corrado
- Lisi Alberto
- Liskova Katarina
- Lois Fernande
- Lubnin Andrey
- Lugovoy Alexander
- Lundberg Michael
- Luzier Elizabeth
- Mackenzie Felicity
- Magdy Mohamed
- Mahran Mohamed
- Maldini Branka
- Mall Merilin
- Maral Jale
- Markovic-Bozic Jasmina
- Marrella Antonella
- Marret Emmanuel
- Marri Sudhakar
- Martinez Francisco Hidalgo
- Martinez Raquel
- Martins Diogo
- Mazul-Sunko Branka
- Mazur Andriy
- Mellin-Olsen Jannicke
- Melo Marcos Vidal
- Mercer Pauline
- Merzky Simone
- Metwally Tarek
- Metzler Helfried
- Mihajlovic Dunja
- Miliauskas Povilas
- Mills Gary
- Mills Gary H.
- Minto Gary
- Mirabella Lucia
- Mirea Liliana
- Mirkovic Ivan
- Miskovic Petar
- Mladic-Batinica Inga
- Mohr Otto
- Moise Alida
- Moldovan Septimiu Gheorghe
- Molin Alexandre
- Molina Ruby
- Momeni Mona
- Monedero Pablo
- Montagnani Luca
- Montalto Francesca
- Monteirosa Angela
- Montgomery Jane
- Morais Erick
- Moral Victoria
- Morelli Paola
- Moret Enrique
- Moreton Sarah
- Mowat Stephen
- Muhardri Dalip
- Musella Giuseppe
- Nadolski Maria
- Negoita Silvius
- Nestler Christian
- Nouris Christos
- Novak-Jankovic Vesna
- Novak-Supe Barbka
- Nunez M. nica Rodriguez
- Nutt Helen
- Oganjan Juri
- Oputric Ivana
- Ovezov Alexey
- Ozbilgin Şule
- Ozgen Serpil Ustalar
- Paddle Jonathan
- Palmer Janet
- Pandazi Aggeliki
- Pannen Benedikt
- Parente Suzana
- Pasin Laura
- Pastor Ernesto
- Pavicic Anna Marija
- Pearse Rupert
- Pejakovic Jasmina
- Pekle-Golez Ana
- Pellerano Giulia
- Pelosi Paolo
- Pelosi Paolo
- Peradze Sopio
- Perez Gisela
- Perez Rocio
- Pernar Selma
- Pesce Caterina Valeria
- Petcu Ana Maria
- Petit Antoine
- Pezzatto Stefano
- Pistidda Laura
- Pizov Reuven
- Plichon Benoit
- Poelaert Jan
- Polakovicova Lenka
- Popescu Mihai
- Portch David
- Pospiech Audrey
- Pourzitaki Chryssa
- Prades Albert
- Prodan Alexandru Bogdan
- Prokoshev Pavel
- Puigbo Carlos
- Pulletz Mark
- Putensen Christian
- Radocaj Tomislav
- Rafi Amir
- Ragazzi Riccardo
- Raimondo Pasquale
- Raineri Santi Maurizio
- Raj Ashok
- Rambhatla Mrutyunjaya
- Rapido Francesca
- Raymode Parizade
- Reske Andreas
- Ricardo Ana
- Riciu Magda
- Rico Jesus
- Robba Chiara
- Roberts Helen
- Rodenas Frederic
- Rodrigues Sara
- Roels Nathalie
- Rogers Elaine
- Rogerson David
- Rose Alastair
- Rousseau Guy
- Rucklidge Matthew
- Ruiz Cristina Saiz
- Russotto Vincenzo
- Sada Fatos
- Saeed Yousif
- Salciute Erika
- Sales Gabriele
- Saltali Ali
- Sances Daniele
- Sanli Suat
- Sanlikarip Ceren
- Sarapuu Kaili
- Sardo Elena
- Saric Jadranka Pavicic
- Sassone Marta Eugenia
- Scavonetto Federica
- Schaefer Maximilian
- Scharffenberg Martin
- Schmid Werner
- Schmid Werner
- Scholes Helen
- Schultz Marcus
- Schultz Marcus J.
- Schwerdtfeger Ben
- Sehovic Mirna
- Selvi Onur
- Sendra Mar
- Senturk Nuzhet Mert
- Senturk Ozgur
- Serpa Neto Ary
- Servillo Giuseppe
- Severgnini Paolo
- Severgnini Paolo
- Severijns Charlotte
- Shafi-Kabiri Amir
- Shelley Ben
- Sher Sara
- Sidiropoulou Tatiana
- Sileo Rosanna
- Simeson Karen
- Simon Antonio Martínez
- Simon Philipp
- Sivrikoz Nukhet
- Skiljic Sonja
- Smekalova Olga
- Smith Thomas
- Sobona Villiam
- Solca Maurizio
- Solier Marc
- Sormus Alar
- Soro Marina
- Sottosanti Vicari
- Spadaro Savino
- Spano Gianluca
- Spieth Peter
- Spindler-Vesel Alenka
- Sprung Juraj
- Stancombe Lucia
- Stourac Petr
- Strazisar Branka
- Stroumpoulis Konstantinos
- Struber Gerd
- Sulemanji Demet
- Sungur Zerrin
- Susarla Jaysimha
- Szewczyk Margaret
- Tareco Glória
- Tarzia Valentina
- Tasoulis Marios-Konstantinos
- Teberaite Zivile
- Temino Maria Jose Yepes
- Theodoraki Kassiani
- Thiem Denny Tran
- Tikuisis Renatas
- Tolcser Zsolt
- Tomescu Dana
- Tomkute Gabija
- Tommasino Concezione
- Toraman Fevzi
- Tredici Stefano
- Treschan Tanja
- Tsaousi Georgia
- Tudoroiu Marian Irinel
- Tze Yeo
- Uhlig Christopher
- Unzueta Mari Carmen
- Urbanek Bernhard
- Valsamidis Dimitrios
- van Beek Rienk
- van de Velde Stijn
- van Limmen Jurgen
- van Malderen Marie-Claire
- van Melkebeek Jeroen
- van Mossevelde Veerle
- Vargas Maria
- Varma Sandeep
- Venkatesh Suresh
- Venturino Marco
- Veres Mihaly
- Verri Marco
- Vidal Melo Marcos F.
- Vinkovic Hrvoje
- Vitkova Katerina
- Vivo Jose Tatay
- Voje Minca
- Volfova Ivana
- Volta Carlo Alberto
- Vorotyntsev Sergiy
- Walker Rachel
- Watt Philip
- Wayman Lisa
- Wegscheider Thomas
- Weingarten Toby
- Weiss Martin
- Welch Leanne
- Werger Alice
- West Claire
- Westerheide Diana
- Wiersma Irene
- Williams John
- Wrigge Hermann
- Wrigge Hermann
- Wutai Stanley
- Wyffels Piet
- Xuereb John
- Yassin Hany
- Yates Susan
- Yildiz Mine
- Yilmaz Murat
- Zafeiropoulou Foteini
- Zalina Karginova
- Zamidei Lucia
- Zangrillo Alberto
- Zelinkova Maria
- Zilic Antonio
- Zoppellari Roberto
- Zuleika Maka
- Zunic Josip
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 02/04/2020
- Field of study
Background: Limited information is available regarding intraoperative ventilator settings and the incidence of postoperative pulmonary complications (PPCs) in patients undergoing neurosurgical procedures. The aim of this post-hoc analysis of the 'Multicentre Local ASsessment of VEntilatory management during General Anaesthesia for Surgery' (LAS VEGAS) study was to examine the ventilator settings of patients undergoing neurosurgical procedures, and to explore the association between perioperative variables and the development of PPCs in neurosurgical patients. Methods: Post-hoc analysis of LAS VEGAS study, restricted to patients undergoing neurosurgery. Patients were stratified into groups based on the type of surgery (brain and spine), the occurrence of PPCs and the assess respiratory risk in surgical patients in Catalonia (ARISCAT) score risk for PPCs. Results: Seven hundred eighty-four patients were included in the analysis; 408 patients (52%) underwent spine surgery and 376 patients (48%) brain surgery. Median tidal volume (VT) was 8 ml [Interquartile Range, IQR = 7.3-9] per predicted body weight; median positive end-expiratory pressure (PEEP) was 5 [3 to 5] cmH20. Planned recruitment manoeuvres were used in the 6.9% of patients. No differences in ventilator settings were found among the sub-groups. PPCs occurred in 81 patients (10.3%). Duration of anaesthesia (odds ratio, 1.295 [95% confidence interval 1.067 to 1.572]; p = 0.009) and higher age for the brain group (odds ratio, 0.000 [0.000 to 0.189]; p = 0.031), but not intraoperative ventilator settings were independently associated with development of PPCs. Conclusions: Neurosurgical patients are ventilated with low VT and low PEEP, while recruitment manoeuvres are seldom applied. Intraoperative ventilator settings are not associated with PPCs
Association between night-time surgery and occurrence of intraoperative adverse events and postoperative pulmonary complications
- Author
- Abdel-Razek Ahmed
- Abdelhady Mahdy
- Abdelwahab Hisham Hosny
- Ahmed Ahmed Gouda
- Akgun Fatma Nur
- Aldecoa Alvares-Santullano Cesar
- Algarsamy Shivarajan
- Almagro Angela
- Amaral Joana
- Andersson Elisabeth
- Andreou Antonis
- Andrew Alyson
- Anipchenko Natalia
- Antholopoulos Georgios
- Appleton Sofia
- Arpino Ines
- Arun Oguzhan
- Aukstakalniene Ruta
- Aun Annika
- Avalos Manuel Vico
- Aydogan Eyup
- Azenic-Venzera Darija
- Babayants Andrey
- Baciarello Marco
- Bacuzzi Alessandro
- Ball L.
- Barrett Colin
- Barsan Victoria
- Bartolini Vittoria
- Bastin Bea
- Bell Andrea
- Bengisun Zuleyha Kazak
- Beran Maud
- Beretta Luigi
- Bezzina Maureen
- Binnekade Jan
- Bluth Thomas
- Boer Christa
- Bona Francesco
- Borg Francis Joseph
- Bos Lieuwe
- Boyd Nicholas
- Boztug Neval
- Brazzi Luca
- Breidablik Alena
- Bressan Filippo
- Brown Lucy
- Brugnoni Elisa
- Brujevic Jan
- Bruncakova Katarina
- Brunelli Andrea
- Brunetti Iole
- Bundy Anette
- Burton Maudrian
- Bystritski Dmitri
- Bytyqi Adem
- Cadilha Susana
- Cain Alistair
- Calton Emily
- Camci Emre
- Campanile Annamaria
- Canet J.
- Canli Seyda
- Carev Mladen
- Carmen Unzueta Mari
- Carvalho Peter
- Castellani Gianluca
- Cerati Giorgia
- Chikungwa Moses
- Chishti Ahmed
- Cindea Iulia
- Cinnella Gilda
- Clements Deborah
- Colley Julie
- Copotoiu Ruxandra
- Copotoiu Sanda-Maria
- Corneci Dan
- Correia Mariana
- Cortegiani A.
- Coskunfirat Nesil
- Costea Dan
- Creagh-Brown Ben
- Creary Thais
- D'antini Davide
- Damster Sandrine
- Das Ashok
- Datson Amanda
- Davies Simon
- de Abajo Larriba Ana
- de Abreu M. Gama
- de Andres Ibanez Jose Antonio
- De Baerdemaeker Luc
- De Bruyne Ann
- de Hert Stefan
- De Jong Jasper
- De Michele Michele
- Deane Jill
- Defez Mario
- Delunas Luigi
- Dennesen Paul
- Di Parma Ambra Licia
- Djonovic-Omanovic Dejana
- Donovan Andrew
- Dossi Roberto
- Drab Michal
- Droc Gabriela
- Dropulic Natasa
- Dudas Radovan
- Dutu Madalina
- Duvekot Anne
- Dvorscak Matea Bogdanovic
- Dylst Dimitri
- Dzurnakova Paula
- Eden Arieh
- el Kafrawy Samir
- El-Shaarawy Ahmed Mostafa
- Ellison Branwen
- Erceg Gorjana
- Everett Lynn
- Fava Josep
- Fedorov Sergei
- Fernandez-Bustamante Ana
- Fernando Luiz
- Ferrando Carlos
- Ferreira Daniel
- Filipescu Daniela
- Filipsky Radek
- Fjellanger Frode
- Florou Panagiota
- Foot Jayne
- Forget Patrice
- Fota Ruxandra
- Fouracres Anna
- Franklin Danielle
- Frkovic Vedran
- Fuller Debbie
- Futier Emmanuel
- Garotescu Ioana Popescu
- Gavranovic Zeljka
- Gecaj-Gashi Agreta
- Geib Johann
- Generali Michela
- Gerard Adeline
- Gherghina Iorel
- Giacoletto Gianmarco
- Giarratano Antonino
- Gibb Sarah
- Gillberg Lars
- Gkiokas Georgios
- Gombotz Hans
- Goncalves Castro Maria de Lurdes
- Goodall Cait
- Goranovic Tanja
- Gottschalk Andre
- Granell Manuel
- Grasso Salvatore
- Gratarola Angelo
- Gregoretti C.
- Grintescu Ioana Cristina
- Grintescu Ioana Marina
- Gritsan Alexey
- Gritsan Galina
- Grosu Irina
- Grynyuk Andriy
- Gueldner Andreas
- Gunenc Ferim
- Guran Catalin-Traian
- Hadimioglu Necmiye
- Harazim Hana
- Hasan Wael Fathy
- Hemmes S. N. T.
- Hemmes Sabrine
- Hering Jens
- Herodes Eiko
- Heyse Bjorn
- Hidalgo Martinez Francisco
- Hiesmayr M.
- Hiesmayr Michael
- Higham Charley
- Hodt Katharina Skirstad
- Hollmann M. W.
- Hollmann Markus
- Homan Elizabeth
- Horhota Lucian
- Hudacek Kamil
- in 't Veld Bas
- Ivars Stefan
- Ivic Dubravka
- Jaber Samir
- Jackson Clare
- Jacobs Tom
- Jammer Ib
- Jawad Monir
- Jirmanova Katerina
- Jones Stephanie
- Jovanov Miroljub
- Jurate Sipylaite
- Juricic Kazimir
- Juros-Zovko Marina
- Kahn David
- Kapkan Tatyana
- Karaman Fatma Mine
- Karanovic Nenad
- Karapanos Dimitris
- Karbonskiene Aurika
- Karjagin Juri
- Kazbek Baturay Kansu
- Kienbaum Peter
- Kiss Thomas
- Kivik Peeter
- Koch Thea
- Kodaganallur Krishnan
- Kolacek Tomas
- Komissarova Irina
- Konrad Mirja
- Kontrimaviciute Egle
- Kopic Jasminka
- Kor Daryl
- Korolkov Oleg
- Kosinova Martina
- Kostadinov Ivan
- Krassler Jens
- Kroell Wolfgang
- Kucukgoncu Semra
- Kucukguclu Semih
- Kulikov Alexander
- Kusnierikova Zuzana
- Kusre Sandeep
- Kuvaki Bahar
- Kvolik Slavica
- La Bella Daniela
- Landoni Giovanni
- Lazukic Aleksandra
- Leva Brigitte
- Leykin Yigal
- Likhvantsev Valery
- Limb James
- Liperi Corrado
- Lisi Alberto
- Liskova Katarina
- Lois Fernande
- Lubnin Andrey
- Lugovoy Alexander
- Lundberg Michael
- Luzier Elizabeth
- Mackenzie Felicity
- Magdy Mohamed
- Mahran Mohamed
- Maldini Branka
- Mall Merilin
- Maral Jale
- Markovic-Bozic Jasmina
- Marrella Antonella
- Marret Emmanuel
- Marri Sudhakar
- Martinez Simon Antonio
- Martinez Raquel
- Martins Diogo
- Mazul-Sunko Branka
- Mazur Andriy
- Mellin-Olsen Jannicke
- Melo M. F. V.
- Melo Marcos Vidal
- Mercer Pauline
- Merzky Simone
- Metwally Tarek
- Metzler Helfried
- Mihajlovic Dunja
- Miliauskas Povilas
- Mills G. H.
- Mills Gary
- Minto Gary
- Mirabella Lucia
- Mirea Liliana
- Mirkovic Ivan
- Miskovic Petar
- Mladic-Batinica Inga
- Mohr Otto
- Moise Alida
- Moldovan Septimiu Gheorghe
- Molin Alexandre
- Molina Ruby
- Momeni Mona
- Monedero Pablo
- Montagnani Luca
- Montalto Francesca
- Monteirosa Angela
- Montgomery Jane
- Morais Erick
- Moral Victoria
- Morelli Paola
- Moret Enrique
- Moreton Sarah
- Mowat Stephen
- Muhardri Dalip
- Musella Giuseppe
- Nadolski Maria
- Negoita Silvius
- Nestler Christian
- Neto A. S.
- Nouris Christos
- Novak-Jankovic Vesna
- Novak-Supe Barbka
- Nutt Helen
- Oganjan Juri
- Oputric Ivana
- Ovezov Alexey
- Ozbilgin Sule
- Ozgen Serpil Ustalar
- Paddle Jonathan
- Palmer Janet
- Pandazi Aggeliki
- Pannen Benedikt
- Parente Suzana
- Pasin Laura
- Pastor Ernesto
- Pavicic Anna Marija
- Pearse Rupert
- Pejakovic Jasmina
- Pekle-Golez Ana
- Pellerano Giulia
- Pelosi P.
- Peradze Sopio
- Perez Gisela
- Perez Rocio
- Pernar Selma
- Pesce Caterina Valeria
- Petcu Ana Maria
- Petit Antoine
- Pezzatto Stefano
- Pistidda Laura
- Pizov Reuven
- Plichon Benoit
- Poelaert Jan
- Polakovicova Lenka
- Popescu Mihai
- Portch David
- Pospiech Audrey
- Pourzitaki Chryssa
- Prades Albert
- Prodan Alexandru Bogdan
- Prokoshev Pavel
- Puigbo Carlos
- Pulletz Mark
- Putensen C.
- Radocaj Tomislav
- Rafi Amir
- Ragazzi Riccardo
- Raimondo Pasquale
- Raineri Santi Maurizio
- Raj Ashok
- Rambhatla Mrutyunjaya
- Rapido Francesca
- Raymode Parizade
- Reske Andreas
- Ricardo Ana
- Riciu Magda
- Rico Jesus
- Roberts Helen
- Rodenas Frederic
- Rodrigues Sara
- Rodriguez Nunez Monica
- Roels Nathalie
- Rogers Elaine
- Rogerson David
- Rose Alastair
- Rousseau Guy
- Rucklidge Matthew
- Russotto Vincenzo
- Sada Fatos
- Saeed Yousif
- Saiz Ruiz Cristina
- Salciute Erika
- Sales Gabriele
- Saltali Ali
- Sances Daniele
- Sanli Suat
- Sanlikarip Ceren
- Sarapuu Kaili
- Sardo Elena
- Saric Jadranka Pavicic
- Sassone Marta Eugenia
- Scavonetto Federica
- Schaefer Maximilian
- Scharffenberg Martin
- Schmid W.
- Schmid Werner
- Scholes Helen
- Schultz M. J.
- Schultz Marcus
- Schwerdtfeger Ben
- Sehovic Mirna
- Selvi Onur
- Sendra Mar
- Senturk Nüzhet Mert
- Senturk Ozgur
- Servillo Giuseppe
- Severgnini P.
- Severgnini Paolo
- Severijns Charlotte
- Shafi-Kabiri Amir
- Shelley Ben
- Sher Sara
- Sidiropoulou Tatiana
- Sileo Rosanna
- Simeson Karen
- Simon Philipp
- Sivrikoz Nukhet
- Skiljic Sonja
- Smekalova Olga
- Smith Thomas
- Sobona Villiam
- Solca Maurizio
- Solier Marc
- Sormus Alar
- Soro Marina
- Sottosanti Luigi Giancarlo Vicari
- Spadaro Savino
- Spano Gianluca
- Spieth Peter
- Spindler-Vesel Alenka
- Sprung Juraj
- Stancombe Lucia
- Stourac Petr
- Strazisar Branka
- Stroumpoulis Konstantinos
- Struber Gerd
- Sulemanji Demet
- Sungur Zerrin
- Susarla Jaysimha
- Szewczyk Margaret
- Tareco Gloria
- Tarzia Valentina
- Tasoulis Marios-Konstantinos
- Tatay Vivo Jose
- Teberaite Zivile
- Theodorak Kassiani
- Thiem Denny Tran
- Tikuisis Renatas
- Tolcser Zsolt
- Tomescu Dana
- Tomkute Gabija
- Tommasino Concezione
- Toraman Fevzi
- Tredici Stefano
- Treschan Tanja
- Tsaousi Georgia
- Tudoroiu Marian Irinel
- Tze Yeo
- Uhlig Christopher
- Urbanek Bernhard
- Valsamidis Dimitrios
- van Beek Rienk
- van de Velde Stijn
- Van Limmen Jurgen
- van Malderen Marie-Claire
- van Melkebeek Jeroen
- van Mossevelde Veerle
- Vargas Maria
- Varma Sandeep
- Venkatesh Suresh
- Venturino Marco
- Veres Mihaly
- Verri Marco
- Vinkovic Hrvoje
- Vitkova Katerina
- Voje Minca
- Volfova Ivana
- Volta Carlo Alberto
- Vorotyntsev Sergiy
- Walker Rachel
- Watt Philip
- Wayman Lisa
- Wegscheider Thomas
- Weingarten Toby
- Weiss Martin
- Welch Leanne
- Werger Alice
- West Claire
- Westerheide Diana
- Wiersma Irene
- Williams John
- Wrigge H.
- Wrigge Hermann
- Wutai Stanley
- Wyffels Piet
- Xuereb John
- Yassin Hany
- Yates Susan
- Yepes Temino Maria Jose
- Yildiz Mine
- Yilmaz Murat
- Zafeiropoulou Foteini
- Zalina Karginova
- Zamidei Lucia
- Zangrillo Alberto
- Zelinkova Maria
- Zilic Antonio
- Zoppellari Roberto
- Zuleika Maka
- Zunic Josip
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2019
- Field of study
Background: The aim of this post hoc analysis of a large cohort study was to evaluate the association between night-time surgery and the occurrence of intraoperative adverse events (AEs) and postoperative pulmonary complications (PPCs)
Prospective observational cohort study on grading the severity of postoperative complications in global surgery research
- Author
- Abayasinghe Chamika
- Abbas Muntadhar
- Abbott T. E. F.
- Abbott Tom
- Abdullah Noor Hairiza
- Abdur-Rahman Lukman
- Abeloos Jacques
- Abernethy Caroline
- Abidin Ucu Nurhadiat
- Abrunhosa Alexandra
- Absar Mohammed
- Adam Suwayba
- Adams George
- Adamson Michael
- Adekola Oyebola
- Adelaja Yemi
- Ademola Adeyinka
- Adenekan Anthony
- Adenike Odewabi
- Adeolu Augustine A
- Adetoye Adedapo
- Adewale Badru
- Adigun Tinuola
- Adolfsson Anne
- Aflori Laura
- Africander Cucu
- Afshari Arash
- Agarwal Vandana
- Agodirin Olayide
- Aguzzoli Crisitiano
- Ahmad Abdurrahman
- Ahmad Norfaizan
- Ahmad T.
- Ahmad Tahania
- Ahmad Yousra
- Ahmed Ahmed
- Ahmed Jamil
- Ahmed Tahania
- Ai Yanqiu
- Aignatoaie Mariana
- Aimoniotou-Georgiou Eleni
- Akanmu Olanrewaju
- Akerman Nik
- Akinwale Mukaila
- Al Amri Khalid
- Al Hussaini Sabah
- Al-Soudaine Yassr
- Aladin Hafiz
- Alagbe-Briggs Olubusola
- Albaj Safauldeensalem
- Alcock David
- Alcock Liam
- Aldecoa Cesar
- Aldecoa Cesar
- Aleixo Fábia Berganton
- Alexander Hazel
- Alexander Maini
- Alexander-Sefre Farhad
- Alherz Fadhel
- Ali Hani
- Ali Marlynn
- Ali Sarah
- Alias Abdul Hafiz
- Alias Anita
- Alias Raja Liza Raja
- Allen Samantha
- Allen Sara Jane
- Allison Joanna
- Alloj Chiara
- Allorto Nikki Leigh
- Allsop Joanne
- Almeida William
- Alonso Eduardo
- Alonso José Ignacio
- Alphonsus Christella
- Alvares Danielle
- Alves Maria Joao
- Amador Juan Carlos Bravo
- Ameer Yusuf
- Amendola Cristina Prata
- Ami Noam
- Amstrup-Hansen Louise
- Anagnou Athina
- Andersen Cheme
- Anderson Charlotte
- Anderson Colette
- Anderson Frank
- Anderson Philip
- Andreadaki Evangelia
- Andreou Alexandros
- Andreou Prematie
- Andrew Alyson
- Andrews Emma
- Angel Miguel Paludi
- Angermair Stefan
- Angus Kirsty
- Anillo Victor
- Anizi Mashel Al
- Antal Oana
- Antill Philip
- Antoniadou Eleni
- Apagaki Eymorfia
- Apostolou Konstantinos
- Applewhaite Christopher
- Applewhaite Christopher
- Aquino Laura Patricia González
- Ar Praburaj
- Araujo Daniela Marques
- Arawwawala Dilshan
- Ardern Diane
- Argue Ruth
- Aribawa Mahaalit Alit
- Arkalaki Eleni
- Armaganidis Apostolos
- Armstrong John
- Armstrong Richard
- Arnaoutoglou Christina
- Arnaoutoglou Elena
- Arnold Glenn
- Arrandale Lindsay
- Arrich James
- Arrigo Mario
- Arshad Homa
- Arshad Mohammed Asif
- Artiles Tania Socorro
- Arumugam Swarna
- Arustei Mirela
- Arvaniti Kostoula
- Arvaniti Kostoula
- Arya Aryabiantara
- Arya Shobhit
- Asimakos Andreas
- Aslam M
- Asudo Felicia
- Athanasakis Elias
- Atiku Mamuda
- Attrill Elizabeth
- Attwood Clare
- Auer Patrick
- Avidan Michael
- Avila Erendira Jocelin Dominguez
- Avis Joanne
- Awad Hadi
- Axioti Elena
- Azam Ummi Azmira Ahmad
- Azambuja Pedro
- Azevedo Caroline
- Aziz Faizal Zuhri
- Baas Peter
- Baghirzada Leyla
- Bai Hui-Ping
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- Cherrett Veronica
- Chetty Rubendraj R
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- Deacon Matthew
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- Del Valle Santiago Garcia
- Delgado García David R
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- Dempster Angie
- Denham Samuel
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- Futier E.
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- Futier Emmanuel
- Gaitanakis Stylianos
- Gall Lewis
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- Gama N Sibusiso
- Gambhir Rajiv
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- Ganter Michael T
- Gao Hong
- Garcia Carolina Soledad Romero
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- Goebel Ulrich
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- Goldberg Olivia
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- Gray Carol
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- Greaves K. E.
- Greaves Rosanna
- Green Garyth M
- Green-Thompson Randolph
- Greene Michael
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- Grey Ben
- Griffiths Ewen
- Grigoras Ioana
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- Haddow J.
- Haddow James
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- Hariharan Vimal
- Harrichandparsad R
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- Hobrok Maria
- Hodgkiss Tracey
- Hodgson Richard E
- Hodzovic Emil
- Hoedt Marielle
- Hoeft Andreas
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- Hofer Christoph
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- Xiong Xiapei
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- Xouplidis Kyriakos
- Xu Guan-Jie
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- Yagnik Anmol
- Yan Yixiu
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- Yang Yang
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- Yao Yurui
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- Yeh Erlinda
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- Yun Bai
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- Zakynthinos Spyros
- Zamudio Diana
- Zangrillo Alberto
- Zapata Darcy Danitza Mari
- Zbitnew Geoff
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- Zeidan Lisa
- Zeng Qiuting
- Zettergren Jan
- Zhang Baoling
- Zhang Enman
- Zhang Huaigen
- Zhang Huan
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- Zhang Mingxiao
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- Zhang Yuan
- Zhao Bing
- Zhao Bo
- Zhao Chong
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- Zhao Jinning
- Zhao Lei
- Zhao Shuna
- Zhao Ting
- Zhao Weihong
- Zhao Weilu
- Zhao Xiaoying
- Zhen Jungang
- Zheng Kang
- Zheng Lina
- Zheng Tianzhao
- Zhong Yi
- Zhou Ce
- Zhou Dachun
- Zhou Haidong
- Zhou Haiyan
- Zhou Jiali
- Zhou Jialong
- Zhou Jing
- Zhou Xian-jin
- Zhu Xiaomao
- Zhu Yi
- Zhu Zhipeng
- Zhuang Xiuxiu
- Zilis Georgios
- Zin Nor Hafizah Mohd
- Zingerle Nicolette
- Zingg Urs
- Zoerner Frank
- Zonneveldt Harry
- Zou Xiaohua
- Zoulamoglou Menelaos
- Zsisku Lajos
- Zundert Tom
- Zyl Rebekka
- åkring Irene
- Ögren Katrin
- Publication venue
- 'Wiley'
- Publication date
- 22/10/2018
- Field of study
Background
The Clavien–Dindo classification is perhaps the most widely used approach for reporting postoperative complications in clinical trials. This system classifies complication severity by the treatment provided. However, it is unclear whether the Clavien–Dindo system can be used internationally in studies across differing healthcare systems in high- (HICs) and low- and middle-income countries (LMICs).
Methods
This was a secondary analysis of the International Surgical Outcomes Study (ISOS), a prospective observational cohort study of elective surgery in adults. Data collection occurred over a 7-day period. Severity of complications was graded using Clavien–Dindo and the simpler ISOS grading (mild, moderate or severe, based on guided investigator judgement). Severity grading was compared using the intraclass correlation coefficient (ICC). Data are presented as frequencies and ICC values (with 95 per cent c.i.). The analysis was stratified by income status of the country, comparing HICs with LMICs.
Results
A total of 44 814 patients were recruited from 474 hospitals in 27 countries (19 HICs and 8 LMICs). Some 7508 patients (16·8 per cent) experienced at least one postoperative complication, equivalent to 11 664 complications in total. Using the ISOS classification, 5504 of 11 664 complications (47·2 per cent) were graded as mild, 4244 (36·4 per cent) as moderate and 1916 (16·4 per cent) as severe. Using Clavien–Dindo, 6781 of 11 664 complications (58·1 per cent) were graded as I or II, 1740 (14·9 per cent) as III, 2408 (20·6 per cent) as IV and 735 (6·3 per cent) as V. Agreement between classification systems was poor overall (ICC 0·41, 95 per cent c.i. 0·20 to 0·55), and in LMICs (ICC 0·23, 0·05 to 0·38) and HICs (ICC 0·46, 0·25 to 0·59).
Conclusion
Caution is recommended when using a treatment approach to grade complications in global surgery studies, as this may introduce bias unintentionally
The surgical safety checklist and patient outcomes after surgery: a prospective observational cohort study, systematic review and meta-analysis
- Author
- Ab Majid Mohd Azuan
- Ab Rahman Ahmad Sufian
- Ab Rahman Rusnah
- Abayasinghe Chamika
- Abbas Muntadhar
- Abbott T. E. F.
- Abbott Tom
- Abd Ghafar Fara Nur Idayu
- Abd Hadi Husni Zaeem
- Abdel Goad Ehab Helmy
- Abdullah Noor Hairiza
- Abdur-Rahman Lukman
- Abeloos Jacques
- Abernethy Caroline
- Abidin Ucu Nurhadiat
- Abrunhosa Alexandra
- Absar Mohammed
- Adam Suwayba
- Adams David
- Adams George
- Adamson Michael
- Adekola Oyebola
- Adelaja Yemi
- Ademola Adeyinka
- Adenekan Anthony
- Adenike Odewabi
- Adeolu Augustine A.
- Adetoye Adedapo
- Adewale Badru
- Adigun Tinuola
- Adolfsson Anne
- Africander Cucu
- Afshari Arash
- Agarwal Vandana
- Agodirin Olayide
- Aguzzoli Crisitiano
- Ahamed khader null
- Ahmad Azam Ummi Azmira
- Ahmad Abdurrahman
- Ahmad Norfaizan
- Ahmad T.
- Ahmad Tahania
- Ahmad Yousra
- Ahmed Ahmed
- Ahmed Jamil
- Ahmed Tahania
- Ai Yanqiu
- Aignatoaie Mariana
- Aimoniotou-Georgiou Eleni
- Akanmu Olanrewaju
- Akerman Nik
- Akinwale Mukaila
- Al Anizi Mashel
- Al hussaini Sabah
- Al'Amri Khalid
- Al-Soudaine Yassr
- Aladin Hafiz
- Alagbe-Briggs Olubusola
- Albaj Safauldeensalem
- Alberto Lisi Zaheer Moolla
- AlbertoVolta Carlo
- Alcock David
- Alcock Liam
- Aldecoa Cesar
- Aleixo Fábia Berganton
- Alexander Hazel
- Alexander Maini
- Alexander-Sefre Farhad
- Alherz Fadhel
- Ali Hani
- Ali Marlynn
- Ali Sarah
- Alias Abdul Hafiz
- Alias Anita
- Alit Mahaalit Aribawa
- Allen Samantha
- Allen Sara Jane
- Allison Joanna
- Alloj Chiara
- Allorto Nikki Leigh
- Allsop Joanne
- Almeida William
- Alonso Eduardo
- Alonso José Ignacio
- Alphonsus Christella
- Alvares Danielle
- Alves Maria Joao
- Amador Juan Carlos Bravo
- Ameer Yusuf
- Amendola Cristina Prata
- Ami Noam
- Amstrup-Hansen Louise
- Anagnou Athina
- Andersen Cheme
- Anderson Charlotte
- Anderson Colette
- Anderson Frank
- Anderson Philip
- Andreadaki Evangelia
- Andreou Alexandros
- Andreou Prematie
- Andrew Alyson
- Andrews Emma
- Angermair Stefan
- Angus Kirsty
- Anillo Victor
- Antal Oana
- Antill Philip
- Antoniadou Eleni
- Antonina Webombesa
- Apagaki Eymorfia
- Apostolou Konstantinos
- Applewhaite Christopher
- Aquino Laura Patricia González
- Ar Praburaj
- Arawwawala Dilshan
- Ardern Diane
- Argue Ruth
- Arkalaki Eleni
- Arlo whitehouse null
- Armaganidis Apostolos
- Armstrong John
- Armstrong Richard
- Arnaoutoglou Christina
- Arnaoutoglou Elena
- Arnold Glenn
- Arrandale Lindsay
- Arrich James
- Arrigo Mario
- Arshad Homa
- Arshad Mohammed Asif
- Artiles Tania Socorro
- Arumugam Swarna
- Arustei Mirela
- Arvaniti Kostoula
- Arya Aryabiantara
- Arya Shobhit
- Asimakos Andreas
- Aslam F Noorbhai M.
- Asudo Felicia
- Athanasakis Elias
- Atiku Mamuda
- Attrill Elizabeth
- Attwood Clare
- Auer Patrick
- Avidan Michael
- Avila Erendira Jocelin Dominguez
- Avis Joanne
- Awad Hadi
- Axioti Elena
- Azambuja Pedro
- Azevedo Caroline
- Aziz Faizal Zuhri
- Baas Peter
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- Baio Thalissa Hermínia
- Bairaktari Aggeliki
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- Balain Birender
- Balaji Packianathaswamy
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- Balanescu Andreea
- Balasubramaniam Madhu
- Baldisserotto Sérgio
- Baldwin Jacqueline
- Baldwin Matthew
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- Bandeira Maria Expedito
- Banerjee Robin
- Bankewitz Carla
- Banner-Goodspeed Valerie
- Bao Qi
- Barcraft-Barnes Helena
- Barneto Lisa
- Barnett Andrew
- Baroselli Antonio
- Barraclough James
- Barras Jean-Pierre
- Barrett Stephen
- Barrett Wendy Joan
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- Bates Alexander
- Bates Sarah
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- Bauchmuller Kris
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- Baxter Linden
- Beaton Ceri
- Beattie Scott
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- Beavis Vanessa
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- Bejia Tarek
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- Belda Margarita Tormo
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- Beltran Anna Valle
- Ben-Menachem Erez
- Benavent Pau
- Benedikt Preckel Osne Kirzner
- Benevento Angelo
- Bengeri Sheshagiri
- Bennett Cambell
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- Beretta Luigi
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- Bester Delia
- Bester Marlet
- Bettega Fernanda
- Bettinelli Alessandra
- Bhardwaj Neeraj
- Bhatia Kailash
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- Bi Yanbing
- Biais Matthieu
- Biccard B. M.
- Biccard Bruce
- Biccard Bruce M.
- Bidd Heena
- Bidgoli Jawad
- Biffen Andrew
- Bignami Elena
- Bilolikar Anjali
- Bin Mustapha Mohd Tarmimi
- Birch Julie
- Bishop David Gray
- Biyase Thuli
- Bizios Christol
- Blackwell Clare
- Blackwood Douglas
- Blaj Mihaela
- Blakemore Stephen P.
- Bland Martin
- Blunt Mark
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- Bocchino Speranza
- Bodansky Daniella
- Bodger Phoebe
- Boer Christa
- Boereboom Catherine
- Boggiano Victoria
- Bogner Gerhard
- Bokkel-Andela Janneke ten
- Bolaji Benjamin
- Bolton David
- Boone Myles
- Boschi Luca
- Boshier Piers
- Botes Marisa
- Botis Ioannis
- Bottini Corrado
- Bottrill Fiona
- Bouchez Stefaan
- Boulton Kerenza
- Bouris Vasilios
- Bourner Lynsey
- Boutsikos Georgios
- Bouwman Arthur
- Bowrey Sarah
- Boxall Leigh
- Boyd Christine
- Bradburn Mike
- Bradley Jacqueline
- Branagan Graham
- Branco Teresa
- Brand Bastiaan
- Brandsborg Birgitte
- Breitenstein Stefan
- Brennan Andrew
- Brennan Emma
- Brenner Laura
- Brincat Maximilian
- Briscoe Richard
- Bristogiannis Sotirios
- Brooke Jenny
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- Broomby Rupert
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- Brown Andrew
- Brown Caroline Wrey
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- Brown Lynne
- Brown Richard
- Brown Robyn
- Browning Julie
- Bruma Dana
- Brunete Tamara
- Brunswicker Annemarie
- Bryant Helen
- Bua Emmanuel
- Buccimazza Ines
- Buckley Sarah
- Buerkle Christian
- Buhre Wolfgang
- Builu Pierre Monji
- Buise Marc
- Bullock Clare
- Bunwarie Bimalshakth
- Burns Karen
- Burrows Lorna
- Burrows Tom
- Burston Ben
- Burtenshaw Andrew
- Burton Megan
- Busuioc Mihai
- Butryn Izabella
- Butt Georgina
- Byrne Kelly
- Bührer Thomas
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- Cang Jing
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- Cao Ying
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- Cardellino Silvano
- Cardosa Jorge
- Cardoso Gutemberg
- Cardy Jon
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- Carr Adrienne
- Carrera Ronald
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- Carroll Jo
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- Chandra Susilo
- Chandrasekharan Shardha
- Chang Yuan Hsuan
- Chaniotaki Fotini
- Charitos Efthimios
- Charlalampidoy Alexandra
- Charles Rob
- Chatterjee Devnandan
- Chatterjee Jayanta
- Chatzimichali Chatzimichali Aikaterini
- Chau Simon
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- Cheah Clarissa
- Cheah Seleen
- Cheeseman Michelle
- Cheing Yushio
- Chen Chao
- Chen Chen
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- Chen Hong
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- Chen Junping
- Chen Lee-lynn
- Chen Linbi
- Chen Liyong
- Chen Pushan
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- Chen Rong
- Chen Shasha
- Chen Shiyu
- Chen Sijia
- Chen Yaqiu
- Chen Yijiao
- Chen Yijun
- Chen Yongjie
- Chen Zhang
- Cheng Baoli
- Cheng Ka Ho
- Cheng Zhonggui
- Cheong Edward
- Cherian Ritchie
- Cherrett Veronica
- Chetty Rubendraj R.
- Chew M. S.
- Chew Michelle
- Chhabra Ashok
- Chicken Dennis-Wayne
- Chilinciuc Ion
- Chin Im Im
- Chirkut Subash
- Chlorou Dimitra
- Choi Hyun-min David
- Choi Stephen
- Chow Lorraine
- Christian Rachel
- Christiansen Ida Cecilie
- Christmas Natasha
- Christodoulidis Gregory
- Christodoulopoulou Theodora
- Christofaki Maria
- Christoforidis Dimitri
- Chronis Christos
- Chu Hiu Man
- Chu Susanna
- Chua Pandora
- Chukkambotla Srikanth
- Chung Chun Kwong Eric
- Cifra Elna
- Ciobanu Cristina
- Ciobotaru Oana Roxana
- Cirstea Emanuel
- Clark Richard
- Clarkson Aisling
- Clarkson Rachel
- Clavien Pierre-Alain
- Claxton Andrew
- Clemmons Karen
- Cloro Luigi Maria
- Clyde Antony
- Cobzaru Isabelle
- Codita Anisoara
- Colangelo Antonio
- Colangelo Chiara
- Colling Kerry
- Collins Hannah
- Collins Michelle
- Collins Nwokoro
- Colvin Carolyn
- Commey Thelma
- Comptaer Nicolas
- Conde Carlos
- Conradie Alae
- Constantin Kathryn
- Cook Tim
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- Copaciu Elena
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- Coppens Marc
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- Cornell Jonathan
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- Dai Hanying
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- Dalampini Eleftheria
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- Duca Alejandro
- Dudgeon Lucy
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- Dunay Artem
- Dunk Nigel
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- Dursin Ade Nurkacan
- Durst Alexander
- Duttchen Kaylene
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- El-Sayed Ahmed
- Elabib Ali
- Elena Gkonezou
- Elferink-Vonk Renske
- Elgasim Magdi
- Ellis Jessica
- Ellis Kate
- Elna Cifra
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- Foord Denise
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- Hodzovic Emil
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- Hoeft Andreas
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- Madansein Rajhmum
- Madaree Anil
- Madiba Thandinkosi E.
- Maharaj Kapil
- Maia Bernardo
- Maiden Jane
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- Matthewman Madeline Coxwell
- Matthews Lewis
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- Mawdsley Matthew
- Maybrier Hannah
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- Naicker Darshan
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- Navarro Carlos Delgado
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- Neela Fiona Mc
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- O'Connor John
- O'connor Laura
- O'Connor Patrick
- O'Donohoe Lynn
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- Odeberg-Wernerman Suzanne
- Oestervig Rebecca Monett
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- Olsen Karsten Skovgaard
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- Omer Omer
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- Oyedepo Olanrewaju Olubukola
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- Pabel Svenja
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- Packianathaswamy Balaji
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- Paikou Fotini
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- Palikyra Iliana
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- Palomares Ana Izquierdo
- Paltoglou Josef
- Paludi Miguel Angel
- Pan Yan
- Pan Yuanming
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- Panagou Georgia-Laura
- Panckhurst Jonathan
- Pande Swati
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- Papaioannou Alexandra
- Papakonstantinou Nikolaos
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- Papapostolou Konstantinos
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- Yagnik Anmol
- Yan Yixiu
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- Yang Yang
- Yao Shanglong
- Yao Yurui
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- Yassaee Arrash
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- Yegnaram Shashikant
- Yeh Erlinda
- Yin Ning
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- Yong Johnny
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- Yuan Jing
- Yuan Yazhuo
- Yuliana Annika
- Zaimi Donika
- Zakynthinos Spyros
- Zamudio Diana
- Zangrillo Alberto
- Zapata Darcy Danitza Mari
- Zbitnew Geoff
- Zeidan Lisa
- Zeng Qiuting
- Zerman Luiza
- Zettergren Jan
- Zhang Baoling
- Zhang Enman
- Zhang Hongyan
- Zhang Huaigen
- Zhang Huan
- Zhang Jie
- Zhang Kai
- Zhang Lina
- Zhang Min
- Zhang Mingxiao
- Zhang Qin
- Zhang Ruilin
- Zhang Shihai
- Zhang Weiwei
- Zhang Xiaoguang
- Zhang Xiaolin
- Zhang Xiaoyan
- Zhang Xuekang
- Zhang Yan
- Zhang Yapping
- Zhang Ye
- Zhang Yuan
- Zhao Bing
- Zhao Bo
- Zhao Chong
- Zhao Jiashi
- Zhao Jinning
- Zhao Lei
- Zhao Lili
- Zhao Shuna
- Zhao Ting
- Zhao Weihong
- Zhao Weilu
- Zhao Xiaoying
- Zhen Jungang
- Zheng Kang
- Zheng Lina
- Zheng Tianzhao
- Zhong Yi
- Zhou Ce
- Zhou Dachun
- Zhou Haidong
- Zhou Haiyan
- Zhou Jiali
- Zhou Jialong
- Zhou Jing
- Zhou Xian-jin
- Zhu Xiaomao
- Zhu Xiaoping
- Zhu Yi
- Zhu Zhipeng
- Zhuang Xiuxiu
- Zilis Georgios
- Zingerle Nicolette
- Zingg Urs
- Zoerner Frank
- Zonneveldt Harry
- Zou Xiaohua
- Zoulamoglou Menelaos
- Zsisku Lajos
- Åkring Irene
- Ögren Katrin
- Publication venue
- Health Sciences Research Commons
- Publication date
- 30/10/2017
- Field of study
© 2017 British Journal of Anaesthesia Background: The surgical safety checklist is widely used to improve the quality of perioperative care. However, clinicians continue to debate the clinical effectiveness of this tool. Methods: Prospective analysis of data from the International Surgical Outcomes Study (ISOS), an international observational study of elective in-patient surgery, accompanied by a systematic review and meta-analysis of published literature. The exposure was surgical safety checklist use. The primary outcome was in-hospital mortality and the secondary outcome was postoperative complications. In the ISOS cohort, a multivariable multi-level generalized linear model was used to test associations. To further contextualise these findings, we included the results from the ISOS cohort in a meta-analysis. Results are reported as odds ratios (OR) with 95% confidence intervals. Results: We included 44 814 patients from 497 hospitals in 27 countries in the ISOS analysis. There were 40 245 (89.8%) patients exposed to the checklist, whilst 7508 (16.8%) sustained ≥1 postoperative complications and 207 (0.5%) died before hospital discharge. Checklist exposure was associated with reduced mortality [odds ratio (OR) 0.49 (0.32–0.77); P\u3c0.01], but no difference in complication rates [OR 1.02 (0.88–1.19); P=0.75]. In a systematic review, we screened 3732 records and identified 11 eligible studies of 453 292 patients including the ISOS cohort. Checklist exposure was associated with both reduced postoperative mortality [OR 0.75 (0.62–0.92); P\u3c0.01; I2=87%] and reduced complication rates [OR 0.73 (0.61–0.88); P\u3c0.01; I2=89%). Conclusions: Patients exposed to a surgical safety checklist experience better postoperative outcomes, but this could simply reflect wider quality of care in hospitals where checklist use is routine