4,981 research outputs found

    Los jóvenes y su relación con los juegos y las plataformas móviles

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    En este artículo se abordan, como marco de referencia, el lugar de la cultura en la vida cotidiana, el papel que el juego ha desempeñado en la cultura y su rol en el ámbito del consumo y práctica cultural. Se analiza la evolución y desarrollo del juego en relación con los avances tecnológicos, la posición preponderante que ocupa esta actividad lúdica en el tiempo libre de los individuos, y la cada vez mayor integración de los dispositivos de plataforma digital en la dinámica del devenir humano

    Videojuegos: un marco de referencia para el estudio de su influencia en el aprendizaje significativo de los jóvenes universitarios

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    Esta investigación presentará los efectos que produce el consumo de los viedojuegos en la comunidad universitaria, en particular en los jóvenes estudiantes. El objetivo es mostrar su relación con otras prácticas de consumo cultural como la lectura, la televisión, la música, el uso de la computadora y los teléfonos inteligentes. Es una reflexión acerca de los cambios que la sociedad ha sufrido en su forma de interactuar a partir del consumo y la práctica virtual de los videojuegos y su relación con los nuevos espacios para su consumo, la interacción con las nuevas plataformas, el aprendizaje significativo que de alguna forma se presenta al consumir este bien cultural a través del manejo de nuevas tecnologías, y a partir de los resultados obtenidos, sugerir nuevos modelos de enseñanza-aprendizaje y la construcción de nuevas políticas culturale

    Postpartum ovarian activity and response to progestagen treatment in rustic beef cows (Spanish Retinta) underfed to simulate their typical ranging conditions

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    Retinta cattle, a rustic beef breed raised in free-ranging conditions in the Southwest of Spain, are adapted to seasonal pasture scarcity but exhibit a prolonged calving interval. This study characterized the ovarian activity and response to progestagen treatment (Synchromate-B type) in feed-restricted, postpartum Retinta cows. Forty cows were fed a restricted diet so that competition among cows resulted in a range of body condition scores (BCS) of 2 through 6 on a 1-9 scale. On the 90th postpartum day, a Norgestomet ear implant was administered to Treated cows (n = 20) for 9 days, followed by a 48-hour period of calf withdrawal. The remaining 20 cows served as Controls. For both groups, daily to weekly blood samples were collected from the 2nd to the 9th month postpartum and assayed for 17-[beta]-estradiol and progesterone. Intact bulls were used for breeding and estrous detection. Calves were weaned at 7-7.5 months of age. Twenty-seven cows showed estrus (on the 16-35th week postpartum) and 24 cows were confirmed pregnant (on the 19-35th week postpartum) by the end of the experiment. Treatment neither affected the conception rate nor the interval from calving to first estrus or to conception. High-BCS cows had greater conception rate and resumed estrous cyclicity and conceived earlier than low-BCS cows. Cows remaining nonpregnant by weaning had a lower and more rapidly decreasing BCS than cows conceiving before weaning. The weekly mean of cumulative progesterone release up to the 3rd week of pregnancy was not affected by treatment but it was greater and increased more rapidly in high- versus low-BCS cows. Peak progesterone values were considerably higher than the values usually reported for other beef cattle breeds. In summary, the Retinta cows in this study exhibited a marked refractoriness to estrous induction/synchronization treatment and had a prolonged postpartum anestrus either at low or adequate BCS levels. Further, undernutrition prolonged the postpartum interval to estrus and conception

    Sex neutralization of heavy pigs from Iberian Peninsula breeds: solutions and limitations

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    This report gives an overview of the production system with Alentejano and Iberian swine breeds, the need for sexual neutralization of these pigs and the possible limitations related to the use of immunocastration (IC). The Alentejano (AL, in Portugal) and Iberian (IB, in Spain) pig breeds are genetically related and are produced under the same free-range system. For the certification of high grade dry-cured products like the ‘Pata Negra’ ham, the animals are slaughtered with an age of at least 14 months and a body weight range of 145-210 kg. During the fattening period pigs have access to acorns and grass from the Mediterranean forest. Until now the gonadectomy of both males (avoid boar taint and aggressive and sexual behaviour) and females (avoid mating by wild boars) is a common practice. The foreseen voluntary end of surgical castration (SC) without pain relief in the EU requires the use of alternatives in these swine breeds management. Taking into account that age and weight are key factors for the final products, the only options are SC with pain relief or IC. However, IC in these systems entails various difficulties and raise questions regarding effectiveness, practicability and effects. Studies in IB pig have shown that for females a 3 dose protocol starting before puberty is effective until the usual slaughter age, suppressing ovarian cyclicity. For males a 3 dose protocol is also needed but in this case the immunisation efficacy has been variable, although a 100% efficacy was recently reached with a protocol in which the 3rd dose was administrated before the acorn-feeding. The effects of IC on male meat quality seem limited, but no information is available regarding cured products. Also, no scientific studies on IC vaccine are available for AL breed. Further studies for protocol optimization and impact of IC on final high grade products from AL and IB pigs are needed

    Undercovering the molecular mechanisms of lipid signalling at ER-PM contact sites in tomato (Solanum lycopersicum) under abiotic stress conditions

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    Abiotic stresses cause large reductions in crop production. Therefore, is important to understand how plants respond in order to develop varieties with increased resistance. Lipid-transport proteins (LTP) are emerging as key players of lipid signaling in response to numerous stresses. Specifically, SYT1, a protein first identified by its role in abiotic stress tolerance, is now recognized as an endoplasmic reticulum-plasma membrane contact site tether capable. Our recent data support that SYT1 in involved on non-vesicular lipid-transport of diacyl glycerol (DAG) through its SMP domain. This data together with the interaction of SYT1 with a diacyl glycerol kinase (DGK) suggest a lipid signaling pathway where the product of phospholipase C, diacylglycerol, might be simultaneously translocated from the plasma membrane to the endoplasmic-reticulum by SYT1 and phosphorylated to phosphatidic acid by DGK at the plasma membrane. Using in vitro biochemical approaches we are investigating the affinity of specific lipid species transported by SYT1 using lipid-competition assays, where a fluorescent lipid competes for SYT1 binding-pocket with different lipid species. Using bioinformatic we are obtaining insight into the lipid signal pathway involving PHOSPHOLIPASE C (PLC), DIACYLGLYCEROL KINASE (DGK) and SYNAPTOTAGMIN1 (SYT1) in tomatoUniversidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

    Sedación y analgesia en pacientes con ventilación mecánica en unidades de cuidado intensivo: una revisión narrativa

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    Trabajo fin de grado en EnfermeríaObjetivo: En el presente trabajo se pretende identificar las últimas líneas de revisión y recomendación de las prácticas de sedoanalgesia en pacientes sometidos a Ventilación Mecánica (VM) en Unidades de Cuidados Intensivos (UCI), observar la representación del rol de la enfermera y la importancia otorgada a esta figura, y explorar la monitorización utilizada para los niveles de sedación y necesidad de analgesia en este contexto. Metodología: Revisión narrativa. La búsqueda se realizó en cinco bases de datos cuya especialización es las Ciencias de la Salud: CUIDEN, SciELO, Cochrane, CINAHL y PUBMED, desde 2013 a 2018. Resultados: 17 de los artículos cumplían los criterios de exclusión e inclusión. Las mayores barreras para la evolución de las prácticas de sedoanalgesia son la falta educativa del personal y el miedo a la sedación ligera y aumento de carga de trabajo, siendo más común en enfermería. Las enfermeras tienen un rol esencial en la monitorización y manejo de la sedoanalgesia, además del uso de escalas. Las más utilizadas para la valoración de pacientes son las RASS y la CPOT. Se observa la importancia de las recomendaciones de las guías PAD en los protocolos/ estrategias implementadas. Conclusiones: Es preciso trabajar la educación del personal, en especial el de enfermería, que presenta más barreras para el avance de la sedoanalgesia, siendo un pilar básico en la monitorización y manejo del paciente crítico. Se debe promover la concienciación del personal de UCI en el seguimiento y aceptación de protocolos/estrategias en vez de centrar la investigación en su renovaciónObjective: This work identifies the latest information about sedoanalgesia practices in patients with Mechanical Ventilation (MV) admitted in Intensive Care Units (ICU), followed by an observation into the responsibilities of the nurse and the importance given to this figure. Moreover, a review of the monitoring techniques used to quantify sedation and pain levels. Methodology: A narrative review was conducted with the use of five databases that specialize in health sciences; notably, CUIDEN, SciELO, Cochrane, CINAHL and PUBMED during the time-period of 2013 to 2018. Results: seventeen of the articles met the exclusion and inclusion criteria. Some of great limitations to the evolution of sedoanalgesia practices are due to staff having a lack of vital knowledge and the fear of light sedation and increased workload, which is becoming increasingly common amongst nurses. Nurses have a fundamental role in monitoring and adjusting sedoanalgesia, in addition to using scales. RASS and the CPOT were commonly used during out assessments of the patients. The importance of the recommendations of the PAD guidelines in the protocols and strategies implemented is observed. Conclusions: we deduced that it was fundamentally important to further educate the staff, specifically nurses that are responsible for preventing the advancement of sedoanalgesia whilst caring and managing the critical patient. The awareness of UCI staff in the monitoring and acceptance of protocols and strategies should be promoted instead of focusing the research on its renewa

    Analysis and Improvement of Knowledge Management Processes in Organizations Using the Business Process Model Notation

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    [EN] Successful knowledge management is one of the main challenges for any kind of organization. This paper aims to enhance knowledge management processes within companies and institutions, by analyzing different processes that are part of common stages along all knowledge management lifecycles de-scribed in the literature. The processes have been modeled using the Business Process Model and Notation with a high abstraction level, in order to cover a wide range of organizations. The paper also presents a possible evolution and enhancement of knowledge management processes using the Business Process Model and Notation diagrams, including the use of superior and better perform-ing technological solutions to support knowledge management processes. As a result, we propose a set of improvements that can be extrapolated to other knowledge management-related business processes

    Kinetic study of pilot-scale supercritical CO2 extraction of rosemary (Rosmarinus officinalis) leaves

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    NOTICE: This is the author’s version of a work that was accepted for publication in Journal of Supercritical Fluids. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Journal of Supercritical Fluids, 55 (2011). http://dx.doi.org/10.1016/j.supflu.2010.09.030Rosmarinus officinalis (rosemary) extracts were obtained in a supercritical pilot-scale plant. Based on experimental information available in the literature for analytical or low-scale processes, extraction temperature and pressure were selected to be 313 K and 30 MPa. At these extraction conditions, the kinetic behavior of the pilot-scale overall extraction curve were determined with respect to yield, antioxidant activity and carnosic acid content. The overall extraction curve was represented using Sovova’s model; the average deviation between measured and calculated yields was lower than 2%. Mass transfer coefficients in the fluid and solid phases were determined and were compared with previous data reported in the literature for low-scale rosemary supercritical extraction. A two-stage depressurization procedure was accomplished and the effect of both on-line fractionation and extraction time on the antioxidant activity of the samples collected was studied. The antioxidant activity of the different fractions could be straight correlated with the carnosic acid content with a regression coefficient of 0.92This work has been financed by Universidad Autónoma de Madrid and Comunidad Autónoma de Madrid (ALIBIRD-S2009/AGR-1469) and project FUN-C-FOOD, CSD2007-00063 (CONSOLIDER-INGENIO) from Ministerio de Ciencia e Innovación, Spain
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