Estrutura financeira empresas ramo de calçados: determinantes entre o modelo tradicional liquidez e modelo dinâmico

The footwear industry in the Brazilian market is made up of 7,700 companies, occupies the third place worldwide in production and the fourth place worldwide as the consumer market. In this context, this research aims to analyze and evaluate the financial results of four publicly traded organizations in the footwear business through the balance sheets for the period 2012 to 2016 published on the website of the Brazilian Securities and Exchange Commission. The work was developed based on the calculations and analysis of liquidity ratios of the traditional model and the dynamic model. The dynamic model first required the reclassification of the balance sheet accounts in order to calculate the base indexes of the model with which the structure that represents the level of financial risk of each organization was identified. This research sought to present a joint analysis between the traditional liquidity model and the dynamic model so that actions are taken that seek the financial balance of organizations both in the short and long term. The methodology applied in the research carried out was characterized as descriptive, as it sought to discover the existence of associations and behaviors of the financial indexes calculated in the analyzed period, being liquidity analysis in the traditional method and in the dynamic method. According to the research result, three structures and financial situations were identified according to the classification proposed in the dynamic model, namely: solid situation, for the company Grendene, unsatisfactory, for the company Alpargatas and terrible for the companies Cambuci and Vulcabrás. A summary table was presented to compare the structure and financial situation, as well as the ranking considering the index that each company used of its short-term resources to finance its long-term investments. Keywords: Financial Structure. Shoes Branch. Traditional Model. Dynamic Model.Esta investigación tiene como objetivo analizar y evaluar los resultados financieros de cuatro organizaciones que cotizan en bolsa en la industria del calzado a través de los balances del período 2012 a 2016 publicados en el sitio web de la Comisión de Bolsa y Valores de Brasil. El trabajo se desarrolló en base a los cálculos y análisis de los índices de liquidez del modelo tradicional y el modelo dinámico. El modelo dinámico primero requería la reclasificación de las cuentas del balance general para calcular los índices básicos del modelo con el que se identificaba la estructura que representa el nivel de riesgo financiero de cada organización. Esta investigación buscó presentar un análisis conjunto entre el modelo de liquidez tradicional y el modelo dinámico para que se tomen medidas que busquen el equilibrio financiero de las organizaciones a corto y largo plazo. La investigación realizada se caracterizó como descriptiva, ya que buscó descubrir la existencia de asociaciones y el comportamiento de los índices financieros calculados en el período analizado. Según el resultado de la investigación, se identificaron tres estructuras y situaciones financieras de acuerdo con la clasificación propuesta en el modelo dinámico, a saber: situación sólida, insatisfactoria y terrible. Se presentó una tabla resumen para comparar la estructura financiera y la situación, así como la clasificación considerando el índice que cada compañía utilizó de sus recursos a corto plazo para financiar sus inversiones a largo plazo.A indústria de calçados no mercado brasileiro é composta por 7,7 mil empresas, ocupa o terceiro lugar mundial em produção e o quarto lugar mundial como mercado consumidor. Neste contexto, esta pesquisa tem por objetivo analisar e avaliar os resultados financeiros de quatro organizações de capital aberto do ramo de calçados por meio dos balanços patrimoniais do período de 2012 a 2016 publicados no site da Comissão de Valores Mobiliários. O trabalho foi desenvolvido com base nos cálculos e análise de índices de liquidez do modelo tradicional e do modelo dinâmico. O modelo dinâmico exigiu primeiramente a reclassificação das contas do balanço patrimonial para que fossem calculados os índices base do modelo com os quais foi identificada a estrutura que representa o nível de risco financeiro de cada organização. Esta pesquisa buscou apresentar uma análise conjunta entre o modelo tradicional de liquidez e o modelo dinâmico para que sejam tomadas ações que busquem o equilíbrio financeiro das organizações tanto no curto como no longo prazo. A metodologia aplicada na pesquisa realizada foi caracterizada como do tipo descritiva, pois buscou descobrir a existência de associações e comportamentos dos índices financeiros calculados no período analisado, sendo análise de liquidez no método tradicional e no método dinâmico. De acordo com o resultado da pesquisa foram identificadas três estruturas e situações financeiras segundo a classificação proposta no modelo dinâmico, sendo elas: situação sólida, para a empresa Grendene, insatisfatória, para a empresa Alpargatas e péssima para as empresas Cambuci e Vulcabrás. Foi apresentado um quadro resumo para comparação da estrutura e situação financeira bem como o ranking considerando o índice que cada empresa utilizou de seus recursos de curto prazo para financiar seus investimentos de longo prazo. Palavras-chaves: Estrutura Financeira. Ramo Calçados. Modelo Tradicional. Modelo Dinâmico

Influência da crise financeira mundial na estrutura econômica das instituições financeiras bancárias brasileiras e seus reflexos no Índice de Basiléia: Uma abordagem comparativa

Amid Credit Crisis that hit financial institutions in several countries between 2008 and 2009, this study aims to examine their effects on the largest Brazilian banks, conducting a study to understand what aspects are involved. And yet, do a survey of the BIS ratio of the first quarter of 2006 until the last quarter of 2011 to assess the impact on the content and variation in the Balance Sheet which contributed to the changes in the index. Its main issue: what is the impact of the credit crisis on the results of the balance sheets of financial institutions, and examining how changes in the BIS ratio? Aims to identify the consequences of the worsening global financial crisis in the index of Basel II on Financial Institutions. It was felt a great influence of Credit Risk in the composition of the Risk of Domestic financial institutions. Risk that intensified after the impact of the crisis, indeed justifiable given the difficulty in obtaining external credit.Em meio a Crise de Crédito que atingiu instituições financeiras de vários países, entre 2008 e 2009, este trabalho pretende analisar seus efeitos para os maiores bancos brasileiros, realizando um estudo para compreender quais aspectos estão envolvidos. E ainda, faz um levantamento do índice de Basiléia do primeiro trimestre de 2006 até o último trimestre de 2009, para avaliar o impacto no índice e na variação no Balanço Patrimonial que mais contribuiu para as modificações no índice. Tem como questão problema: qual o impacto causado pela crise de crédito nos resultados dos balanços das instituições financeiras, tendo como análise as modificações no índice de Basiléia? Tem como objetivo Identificar os reflexos do agravamento da crise financeira mundial no índice de Basiléia II das Instituições Financeiras. Percebeu-se uma grande influência do Risco de Crédito na composição dos Riscos das Instituições Financeiras Nacionais. Risco este intensificado após o impacto da crise, fato justificável diante da dificuldade na obtenção de crédito externo

Impact of SNPs/haplotypes of IL10 and IFNG on the development of diffuse large B-Cell lymphoma

The purpose of this study was to assess the influence of single-nucleotide polymorphisms (SNPs) on cytokine genes in the development of diffuse large B-cell lymphoma (DLBCL). One hundred and twelve patients and 221 controls were investigated. Among them, 97 patients treated with R-CHOP were subdivided into two groups: (i) complete remission of the disease and (ii) patients who progressed to death, relapsed, or had disease progression. The SNPs investigated by PCR-SSP were TNF -308G>A (rs1800629), IFNG +874A>T (rs2430561), IL6 -174G>C (rs1800795), IL10 -1082A>G (rs1800896), IL10 -819C>T (rs1800871), IL10 -592C>A (rs1800872), and TGFB1 codon10T>C (rs1982073) and codon25G>C (rs1800471). In general, the genotypes that have been associated in the literature with lower production or intermediate production of IL-10 and higher production of IFN-gamma were associated with the protection of the development of the disease, possibly favoring the Th1 immune response and diminishing the capacity of cell proliferation. However, patients receiving R-CHOP treatment presented unfavorable prognoses in the presence of genotypes related to the intermediate production of IL-10 and high production of TGF-beta 1, indicating that cytokines may be related to the response to treatment and action mechanisms of Rituximab2019CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQCOORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPESFUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESPnão temnão temnão te

Plant Macromolecules as Biomaterials for Wound Healing

Natural biomolecules are increasingly relevant for biomedical applications and tissue engineering for being able to produce an effect on chemical signals, organization of cells, and restitution of extracellular matrix in lesioned tissues. In this chapter, we will address the potential of plant macromolecules, in particular, carbohydrates and proteins such as hemicelluloses and lectins. While lectins are mostly carbohydrate-binding proteins, which can interact with cell surfaces to initiate anti-inflammatory pathways, as well as immunomodulatory functions, hemicelluloses are remarkably known by their ability to form viscous solutions even at low concentrations, which makes them an excellent candidate as vehicle to carry different sorts of biomolecules. Taking into account the complexity of the whole healing process, as an overlapping and coordinated cascade of events, most of the properties presented here by those materials may be of interest to the wound-care market

International multicenter observational study on assessment of ventilatory management during general anaesthesia for robotic surgery and its effects on postoperative pulmonary complication (AVATaR) : study protocol and statistical analysis plan

Introduction: Robotic-assisted surgery (RAS) has emerged as an alternative minimally invasive surgical option. Despite its growing applicability, the frequent need for pneumoperitoneum and Trendelenburg position could significantly affect respiratory mechanics during RAS. AVATaR is an international multicenter observational study aiming to assess the incidence of postoperative pulmonary complications (PPC), to characterise current practices of mechanical ventilation (MV) and to evaluate a possible association between ventilatory parameters and PPC in patients undergoing RAS. Methods and analysis: AVATaR is an observational study of surgical patients undergoing MV for general anaesthesia for RAS. The primary outcome is the incidence of PPC during the first five postoperative days. Secondary outcomes include practice of MV, effect of surgical positioning on MV, effect of MV on clinical outcome and intraoperative complications. Ethics and dissemination: This study was approved by the Institutional Review Board of the Hospital Israelita Albert Einstein. The study results will be published in peer-reviewed journals and disseminated at international conferences. Trial registration number: NCT02989415; Pre-results

The VISCACHA survey-deep and resolved photometry of star clusters in the Magellanic Clouds

The VISCACHA (VIsible Soar photometry of star Clusters in tApii and Coxi HuguA†) Survey is an ongoing project based on deep and spatially resolved photometric observations of Magellanic Cloud star clusters, collected using the SOuthern Astrophysical Research (SOAR) telescope together with the SOAR Adaptive Module Imager. So far we have used >300h of telescope time to observe ∼150 star clusters, mostly with low mass (M < 104M⊠) on the outskirts of the LMC and SMC. With this high-quality data set, we homogeneously determine physical properties using deep colour-magnitude diagrams (ages, metallicities, reddening, distances, mass, luminosity and mass functions) and structural parameters (radial density profiles, sizes) for these clusters which are used as a proxy to investigate the interplay between the Magellanic Clouds and their evolution. We present the VISCACHA survey and its initial results, based on our first two papers. The project's long term goals and expected legacy to the community are also addressed.Fil: Dias, Bruno. European Southern Observatory Chile; Chile. Universidad Andrés Bello; ChileFil: Maia, Francisco. Universidade Federal do Rio de Janeiro; BrasilFil: Kerber, Leandro. Universidade Estadual de Santa Cruz; BrasilFil: Dos Santos, João F. C.. Universidade Federal de Minas Gerais; BrasilFil: Bica, Eduardo. Universidade Federal do Rio Grande do Sul; BrasilFil: Armond, Tina. Universidade Federal de São João del Rei; BrasilFil: Barbuy, Beatriz. Universidade de Sao Paulo; BrasilFil: Fraga, Luciano. Laboratório Nacional de Astrofísica; BrasilFil: Hernandez Jimenez, Jose A.. Universidad Andrés Bello; ChileFil: Katime Santrich, Orlando J.. Universidade Estadual de Santa Cruz; BrasilFil: Oliveira, Raphael A. P.. Universidade de Sao Paulo; BrasilFil: Pérez Villegas, Angeles. Universidade de Sao Paulo; BrasilFil: Piatti, Andres Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Astronomía Teórica y Experimental. Universidad Nacional de Córdoba. Observatorio Astronómico de Córdoba. Instituto de Astronomía Teórica y Experimental; ArgentinaFil: Quint, Bruno. Observatorio Gemini; ChileFil: Sanmartin, David. Observatorio Gemini; ChileFil: Angelo, Mateus S.. Centro Federal de Educação Tecnológica de Minas Gerais; BrasilFil: Souza, Stefano O.. Universidade de Sao Paulo; BrasilFil: Vieira, Rodrigo G.. Universidade de Sao Paulo; BrasilFil: Westera, Pieter. Universidad Federal Do Abc; BrasilFil: Parisi, Maria Celeste. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Astronomía Teórica y Experimental. Universidad Nacional de Córdoba. Observatorio Astronómico de Córdoba. Instituto de Astronomía Teórica y Experimental; ArgentinaFil: Geisler, Doug. Universidad de La Serena; Chile. Universidad de Concepción; ChileFil: Minniti, Dante. Universidad Andrés Bello; Chile. Millennium Institute of Astrophysics; Chile. Vatican Observatory; ItaliaFil: Saito, Roberto. Universidade Federal de Santa Catarina; BrasilFil: Bassino, Lilia Patricia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Astrofísica La Plata. Universidad Nacional de La Plata. Facultad de Ciencias Astronómicas y Geofísicas. Instituto de Astrofísica La Plata; ArgentinaFil: de Bórtoli, Bruno Javier. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Astrofísica La Plata. Universidad Nacional de La Plata. Facultad de Ciencias Astronómicas y Geofísicas. Instituto de Astrofísica La Plata; ArgentinaFil: Figueiredo, André. Universidade de Sao Paulo; BrasilFil: Rímulo, Leandro. Universidad de los Andes; Colombi

Measurement of the cosmic ray spectrum above 4×10184{\times}10^{18} eV using inclined events detected with the Pierre Auger Observatory

A measurement of the cosmic-ray spectrum for energies exceeding $4{\times}10^{18}$ eV is presented, which is based on the analysis of showers with zenith angles greater than $60^{\circ}$ detected with the Pierre Auger Observatory between 1 January 2004 and 31 December 2013. The measured spectrum confirms a flux suppression at the highest energies. Above $5.3{\times}10^{18}$ eV, the "ankle", the flux can be described by a power law $E^{-\gamma}$ with index $\gamma=2.70 \pm 0.02 \,\text{(stat)} \pm 0.1\,\text{(sys)}$ followed by a smooth suppression region. For the energy ($E_\text{s}$) at which the spectral flux has fallen to one-half of its extrapolated value in the absence of suppression, we find $E_\text{s}=(5.12\pm0.25\,\text{(stat)}^{+1.0}_{-1.2}\,\text{(sys)}){\times}10^{19}$ eV.Comment: Replaced with published version. Added journal reference and DO