293 research outputs found

    A Second Report on the Experiments with Programs for the Simulation of Large Scale Automata on a Digital Computer

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    Control Systems Laboratory changed its name to Coordinated Science LaboratoryContract DA-36-039-SC-5669

    Experiments with Programs for the Simulation of Large Scale Automata on a Digital Computer

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    Control Systems Laboratory changed its name to Coordinated Science LaboratoryContract DA-36-039-SC-5669

    A Simple Colorimetric Method for the Estimation of Relative Numbers of Lactobacilli in the Saliva

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/67295/2/10.1177_00220345400190040101.pd

    Revised timing of cenozoic atlantic incursions and changing hinterland sediment sources during southern patagonian orogenesis

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    New detrital zircon U-Pb geochronology data from the Cenozoic Magallanes-Austral Basin in Argentina and Chile ~51° S establish a revised chronostratigraphy of Paleocene-Miocene foreland synorogenic strata and document the rise and subsequent isolation of hinterland sources in the Patagonian Andes from the continental margin. The upsection loss of zircons derived from the hinterland Paleozoic and Late Jurassic sources between ca. 60 and 44Ma documents a major shift in sediment routing due to Paleogene orogenesis in the greater Patagonian-Fuegian Andes. Changes in the proportion of grains from hinterland thrust sheets, comprised of Jurassic volcanics and Paleozoic metasedimentary rocks, provide a trackable signal of long-term shifts in orogenic drainage divide and topographic isolation due to widening of the retroarc fold-thrust belt. The youngest detrital zircon U-Pb ages confirm timing of Maastrichtian-Eocene strata but require substantial age revisions for part of the overlying Cenozoic basinfill during the late Eocene and Oligocene. The upper Río Turbio Formation, previously mapped as middle to late Eocene in the published literature, records a newly recognized latest Eocene-Oligocene (37-27Ma) marine incursion along the basin margin. We suggest that these deposits could be genetically linked to the distally placed units along the Atlantic coast, including the El Huemul Formation and the younger San Julián Formation, via an eastward deepening within the foreland basin system that culminated in a basin-wide Oligocene marine incursion in the Southern Andes. The overlying Río Guillermo Formation records onset of tectonically generated coarse-grained detritus ca. 24.3Ma and a transition to the first fully nonmarine conditions on the proximal Patagonian platform since Late Cretaceous time, perhaps signaling a Cordilleran-scale upper plate response to increased plate convergence and tectonic plate reorganization.Fil: Fosdick, Julie C.. University of Connecticut; Estados UnidosFil: VanderLeest, R. A.. University of Connecticut; Estados UnidosFil: Bostelmann, J. E.. Universidad de Chile; ChileFil: Leonard, J. S.. Arizona State University; Estados UnidosFil: Ugalde, R.. Universidad Mayor; ChileFil: Oyarzún, J. L.. Parque Geo-paleontológico la Cumbre-baguales; ChileFil: Griffin, Miguel. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. División Paleozoología Invertebrados; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentin

    On general measures of deformation

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    Each particle of a continuum is assigned a second order tensor which is taken as a measure of the deformation of some neighborhood of the particle, and which is determined by a functional depending on the configurations of that neighborhood. Two invariance restrictions are imposed on the functional whose values are spatial strain tensors, that is, associated with the deformed configuration. The first requirement is that a time shift and rigid transformation of the deformed configuration leave the spatial deformation tensor unaltered relative to it. The second requires that if particles of distinct continua undergo the same deformation, the corresponding deformation tensors should be the same. For the special case in which the functional depends on the deformation in the smallest neighborhood of a particle, the restrictions imply that the deformation tensors associated with the deformed and reference configurations are isotropic functions of the left and right Cauchy-Green tensors, respectively. Jedem Teilchen eines Kontinuums wird ein Tensor zweiter Stufe als Maß für die Deformation einer gewissen Nachbarschaft dieses Teilchen zugeordnet, der durch ein Funktional bestimmt wird, das von der Konfiguration dieser Nachbarschaft abhängt. Zwei Invarianzbedingungen werden diesem Funktional, dessen Werte räumliche Verzerrungstensoren darstellen, auferlegt, und zwar im Hindblick auf die deformierte Konfiguration. Die erste Forderung besagt, daß eine Zeitverschiebung und eine starre Transformation der deformierten Konfiguration den räumlichen Verzerrungstensor im Hinblick auf diese ungeändert lassen. Die zweite Einschränkung besagt, daß entsprechende Deformationstensoren von Partikeln verschiedener Kontinua, die dieselbe Verformung erlitten haben, gleich sein sollen. Im Spezialfall, daß die Funktionale nur von der Deformation in der nächsten Umgebung des Partikels abhängen, beinhalten die Einschränkungen die Aussage, daß die mit dem deformierten und dem undeformierten Zustand verknüpften Deformationstensoren nur isotrope Funktionen des linken und des rechten Cauchy-Green Tensors sein können.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/41717/1/707_2005_Article_BF01172146.pd

    Toll-Like Receptor 8 Agonist and Bacteria Trigger Potent Activation of Innate Immune Cells in Human Liver

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    This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.The study was supported by a Grant core funding from the Agency for Science Technology and Research (A*STAR, Singapore) and a Singapore Translational Research Investigator Award (NRMC/StaR/013/2012) to AB as well as NIHR Biomedical Centre, Oxford, WT 091663MA, NIAID1U19AI082630-01, Oxford Martin School funding and an NIHR Senior Investigator award to PK

    Thermomechanical couplings in shape memory alloy materials

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    In this work we address several theoretical and computational issues which are related to the thermomechanical modeling of shape memory alloy materials. More specifically, in this paper we revisit a non-isothermal version of the theory of large deformation generalized plasticity which is suitable for describing the multiple and complex mechanisms occurring in these materials during phase transformations. We also discuss the computational implementation of a generalized plasticity based constitutive model and we demonstrate the ability of the theory in simulating the basic patterns of the experimentally observed behavior by a set of representative numerical examples
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